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REVIEW

Research status of the regulation of miRNA on BACE1

, &
Pages 474-477 | Received 26 Aug 2013, Accepted 19 Oct 2013, Published online: 21 Nov 2013

References

  • Shioya M, Obayashi S, Tabunoki H, Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3. Neuropathol Appl Neurobiol 2010;36(4):320–30.
  • Russo G, Giordano A. miRNAs: from biogenesis to networks. Methods Mol Biol 2009;563:303–52.
  • Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: microRNAs can up-regulate translation. Science 2007;318(5858):1931–4.
  • Sun X, Bromley-brits K, Song W. Regulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer's disease. J Neuronchem 2012;1:62–70.
  • Matsui T, Ingelsson M, Fukumoto H, Expression of APP pathway mRNAs and proteins in Alzheimer's disease. Brain Res 2007;1161:116–23.
  • Bigl M, Apelt J, Luschekina EA, Expression of beta-secretase mRNA in transgenic Tg2576 mouse brain with Alzheimer plaque pathology. Neurosci Lett 2000; 292(2): 107–10.
  • Ling KH, Brautigan PJ, Hahn CN, Deep sequencing analysis of the developing mouse brain reveals a novel microRNA. BMC Genomics 2011;12:176.
  • Kole AJ, Swahari V, Hammond SM, miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis. Genes Dev 2011;25(2):125–30.
  • Hébert SS, Horré K, Nicolaï L, Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci USA 2008;105(17):6415–20.
  • Zong Y, Wang H, Dong W, miR-29c regulates BACE1 protein expression. Brain Res 2011;1395:108–15.
  • Wang WX, Rajeev BW, Stromberg AJ, The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 2008;28(5):1213–23.
  • Nelson PT, Wang WX. MiR-107 is reduced in Alzheimer disease brain neocortex: validation study. J Alzheimers Dis 2010;21(1):75–9.
  • Boissonneault V, Plante I, Rivest S, MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1. J Biol Chem 2009; 284(4):1971–81.
  • Faghihi MA, Zhang M, Huang J, Evidence for natural antisense transcript-mediated inhibition of microRNA function. Genome Biol 2010;11(5):R56.
  • Yu JY, Chung KH, Deo M, MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation. Exp Cell Res 2008;314(14):2618-33.
  • Lim LP, Lau NC, Garrett- Engele P, Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005;433(7027):769–73.
  • Makeyev EV, Zhang J, Carrasco MA, The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell 2007;27(3):435–48.
  • Smith P, Al Hashimi A, Girard J, In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs. J Neurochem 2011;116(2):240–7.
  • Marong Fang, Jing Wang, Xiaobing Zhang, The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease. Toxicol Lett 2012;209(1):94–105.
  • Finnerty JR, Wang WX, Hébert SS, The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases. J Mol Biol 2010;402(3):491–509.
  • Zhu HC, Wang LM, Wang M, MicroRNA-195 downregulates Alzheimer's disease amyloid-β production by targeting BACE1. Brain Res Bull 2012;88(6):596–601.
  • Ding Y, Tian M, Liu J, Expression profile of miRNAs in APP swe/PSΔE9 transgenic mice. Nan Fang Yi Ke Da Xue Xue Bao 2012;32(9):1280–3.
  • Tian M, Ding Y, Hou DR, Real-time PCR for detecting differential expressions of microRNAs in the brain of a transgenic mouse model of Alzheimer's disease. Nan Fang Yi Ke Da Xue Xue Bao 2013;33(2):262–6.
  • Roberds SL, Anderson J, Basi G, BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics. Hum Mol Genet 2001;10(12):1317–24.
  • Luo Y, Bolon B, Damore MA, BACE1 (beta-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over time. Neurobiol Dis 2003;14(1):81–8.
  • Li Q, Südhof TC. Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1. J Biol Chem 2004;279(11):10542–50.
  • Falls DL. Neuregulins: functions, forms, and signaling strategies. Exp Cell Res 2003;284(1):14–30.
  • McEver RP, Cummings RD. Perspectives series: cell adhesion in vascular biology. Role of PSGL-1 binding to selectins in leukocyte recruitment. J Clin Invest 1997;100(3):485–91.
  • Hitt B, Riordan SM, Kukreja L, β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects. J Biol Chem 2012;287(46):38408–25.
  • Willem M, Garratt AN, Novak B, Control of peripheral nerve myelination by the beta-secretase BACE1. Science 2006;314(5799):664–6.

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