314
Views
26
CrossRef citations to date
0
Altmetric
Original Article

Combining restricted diet with forced or voluntary exercises improves hippocampal BDNF and cognitive function in rats

, , &
Pages 366-373 | Received 02 Dec 2014, Accepted 23 Jan 2015, Published online: 05 Jun 2015

References

  • Bouchard C, Blair SN, Haskell WL. Physical activity and health. Champaign, IL: Human Kinetics; 2007. xiii, 409 pp.
  • Gomez-Pinilla F. Brain foods: the effects of nutrients on brain function. Nat Rev Neurosci 2008;9(7):568–78.
  • van Praag H. Exercise and the brain: something to chew on. Trends Neurosci 2009;32(5):283–90.
  • Hillman CH, Erickson KI, Kramer AF. Be smart, exercise your heart: exercise effects on brain and cognition. Nat Rev Neurosci 2008;9(1):58–65.
  • Mello PB, Benetti F, Cammarota M, Izquierdo I. Effects of acute and chronic physical exercise and stress on different types of memory in rats. An Acad Bras Cienc 2008;80(2):301–9.
  • Autry AE, Monteggia LM. Brain-derived neurotrophic factor and neuropsychiatric disorders. Pharmacol Rev 2012;64(2):238–58.
  • Greenberg ME, Xu B, Lu B, Hempstead BL. New insights in the biology of BDNF synthesis and release: implications in CNS function. J Neurosci 2009;29(41):12764–7.
  • Khabour OF, Alzoubi KH, Alomari MA, Alzubi MA. Changes in spatial memory and BDNF expression to concurrent dietary restriction and voluntary exercise. Hippocampus 2010;20(5):637–45.
  • Khabour OF, Alzoubi KH, Alomari MA, Alzubi MA. Changes in spatial memory and BDNF expression to simultaneous dietary restriction and forced exercise. Brain Res Bull 2012;90:19–24.
  • Alomari MA, Khabour OF, Alzoubi KH, Alzubi MA. Forced and voluntary exercises equally improve spatial learning and memory and hippocampal BDNF levels. Behav Brain Res 2013;247:34–9.
  • Schultz RL, Swallow JG, Waters RP, et al. Effects of excessive long-term exercise on cardiac function and myocyte remodeling in hypertensive heart failure rats. Hypertension 2007;50(2):410–6.
  • Alzoubi KH, Abdul-Razzak KK, Khabour OF, et al. Adverse effect of combination of chronic psychosocial stress and high fat diet on hippocampus-dependent memory in rats. Behav Brain Res 2009;204(1):117–23.
  • Alzoubi KH, Khabour OF, Salah HA, Abu Rashid BE. The combined effect of sleep deprivation and western diet on spatial learning and memory: role of BDNF and oxidative stress. J Mol Neurosci 2012;50(1):124–33.
  • Alzoubi KH, Srivareerat M, Tran TT, Alkadhi KA. Role of alpha7- and alpha4beta2-nAChRs in the neuroprotective effect of nicotine in stress-induced impairment of hippocampus-dependent memory. Int J Neuropsychopharmacol 2013;16(5):1105–13.
  • Pedersen BK, Pedersen M, Krabbe KS, et al. Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals. Exp Physiol 2009;94(12):1153–60.
  • Alzoubi KH, Khabour OF, Salah HA, Hasan Z. Vitamin E prevents high-fat high-carbohydrates diet-induced memory impairment: the role of oxidative stress. Physiol Behav 2013;119C:72–8.
  • Moyse E, Bedard K, Segura S, et al. Effects of aging and caloric restriction on brainstem satiety center signals in rats. Mech Ageing Dev 2012;133(2–3):83–91.
  • Murray AJ, Knight NS, Cochlin LE, et al. Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding. FASEB J 2009;23(12):4353–60.
  • Zoladz JA, Pilc A. The effect of physical activity on the brain derived neurotrophic factor: from animal to human studies. J Physiol Pharmacol 2010;61(5):533–41.
  • Knaepen K, Goekint M, Heyman EM, Meeusen R. Neuroplasticity - exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects. Sports Med 2010;40(9):765–801.
  • Coelho FG, Gobbi S, Andreatto CA, et al. Physical exercise modulates peripheral levels of brain-derived neurotrophic factor (BDNF): a systematic review of experimental studies in the elderly. Arch Gerontol Geriatr 2013;56(1):10–5.
  • Gomez-Pinilla F. The combined effects of exercise and foods in preventing neurological and cognitive disorders. Prev Med 2011;52(Suppl 1):S75–80.
  • Pinilla FG. The impact of diet and exercise on brain plasticity and disease. Nutr Health 2006;18(3):277–84.
  • Wu A, Ying Z, Gomez-Pinilla F. Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition. Neuroscience 2008;155(3):751–9.
  • Chytrova G, Ying Z, Gomez-Pinilla F. Exercise contributes to the effects of DHA dietary supplementation by acting on membrane-related synaptic systems. Brain Res 2010;1341:32–40.
  • Stranahan AM, Lee K, Martin B, et al. Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice. Hippocampus 2009;19(10):951–61.
  • Arida RM, Scorza CA, da Silva AV, et al. Differential effects of spontaneous versus forced exercise in rats on the staining of parvalbumin-positive neurons in the hippocampal formation. Neurosci Lett 2004;364(3):135–8.
  • Leasure JL, Jones M. Forced and voluntary exercise differentially affect brain and behavior. Neuroscience 2008;156(3):456–65.
  • Zoladz JA, Majerczak J, Zeligowska E, et al. Moderate-intensity interval training increases serum brain-derived neurotrophic factor level and decreases inflammation in Parkinson's disease patients. J Physiol Pharmacol 2014;65(3):441–8.
  • Rojas Vega S, Struder HK, Vera Wahrmann B, et al. Acute BDNF and cortisol response to low intensity exercise and following ramp incremental exercise to exhaustion in humans. Brain Res 2006;1121(1):59–65.
  • Ferris LT, Williams JS, Shen CL. The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function. Med Sci Sports Exer 2007;39(4):728–34.
  • Gomez-Pinilla F, Ying Z, Roy RR, et al. Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity. J Neurophysiol 2002;88(5):2187–95.
  • Dupont-Versteegden EE, Houle JD, Dennis RA, et al. Exercise-induced gene expression in soleus muscle is dependent on time after spinal cord injury in rats. Muscle Nerve 2004;29(1):73–81.
  • Lindholm D, Castrén E, Berzaghi MdP, Thoenen H, eds. Effects of neurotransmitters and hormones on neuronal production of neurotrophins. Seminars Neurosci 1993;5(4):279–83.
  • Lindholm D, Castren E, Berzaghi M, et al. Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain–implications for neuronal plasticity. J Neurobiol 1994;25(11):1362–72.
  • Alomari MA, Keewan EF, Qhatan R, et al. Blood pressure and circulatory relationships with physical activity level in young normotensive individuals: IPAQ validity and reliability considerations. Clin Exp Hypertens 2011;33(5):345–53.
  • Pescatello LS, Franklin BA, Fagard R, et al. American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exer 2004;36(3):533–53.
  • Cornelissen VA, Fagard RH. Effects of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors. Hypertension 2005;46(4):667–75.
  • Wan R, Weigand LA, Bateman R, et al. Evidence that BDNF regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability. J Neurochem 2014;129(4):573–80.
  • Julius S, Esler M. Autonomic nervous cardiovascular regulation in borderline hypertension. Am J Cardiol 1975;36(5):685–96.
  • Convertino VA. Gender differences in autonomic functions associated with blood pressure regulation. Am J Physiol 1998;275(6 Pt 2):R1909–20.
  • Schmolesky MT, Webb DL, Hansen RA. The effects of aerobic exercise intensity and duration on levels of brain-derived neurotrophic factor in healthy men. J. Sports Sci Med 2013;12(3):502–11.
  • Schmidt-Kassow M, Schadle S, Otterbein S, et al. Kinetics of serum brain-derived neurotrophic factor following low-intensity versus high-intensity exercise in men and women. Neuroreport 2012;23(15):889–93.
  • Aguiar AS, Jr., Tuon T, Pinho CA, et al. Intense exercise induces mitochondrial dysfunction in mice brain. Neurochem Res 2008;33(1):51–8.
  • Dabidi RV, Hosseinzadeh S, Mahjoub S, et al. Endurance exercise training and diferuloyl methane supplement: changes in neurotrophic factor and oxidative stress induced by lead in rat brain. Biol Sport/Inst. Sport 2013;30(1):41–6.
  • Heyman E, Gamelin FX, Goekint M, et al. Intense exercise increases circulating endocannabinoid and BDNF levels in humans–possible implications for reward and depression. Psychoneuroendocrinology 2012;37(6):844–51.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.