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Editorial Article

The Pineal Gland and Multiple Sclerosis

Pages 205-215 | Published online: 07 Jul 2009

References

  • Adeloye A., Felson B. Incidence of normal pineal gland calcification in skull roengenograms of black and white Americans. American Journal of Radiology 1974; 122: 503–507
  • Ader R. Psychoneuroimmunology. Academic Press, New York 1981
  • Aldegunde M., Miguez I., Veira J. Effects of pinealectomy on regional brain serotonin metabolism. International Journal of Neuroscience 1985; 26: 9–13
  • Antel J. P., Cashman N. R. Human retrovirus and multiple sclerosis. Mayo Clinic Proceedings 1991; 66: 752–755
  • Anton-Tay F. Melatonin: effects on brain function. Advances in Biochemical Psychopharma-cology 1974; 11: 315–324
  • Arendt J. Melatonin assays in body fluids. Journal of Neural Transmission 1978; 265–278, (suppl 13)
  • Aschoff J. Disorders of the circadian system as discussed in psychiatric research. Circadian rhythms in psychiatry, T. A. Wehr, F. K. Goodwin. Boxwood Press, Pacific Grove, California 1983
  • Axelrod J. The pineal gland: a neurochemical transducer. Chemical signals from nerves regulate synthesis of melatonin and convey information about internal clocks. Science 1974; 184: 1341–1348
  • Bamford C. R., Sibley W. A., Thies C. Seasonal variation of MS exacerbations in Arizona. Neurology 1983; 33: 1537–1544
  • Bardasano J. L., Meyer A. J., Picazo L. Ultrastructure of the pineal cells of the homing pigeon Columba livia and magnetic fields (first trials). Journal fuer Hirnforschung 1985; 26: 471–475
  • Beebe G. W., Kurtzke J. F., Karland L. T., Auth T. L., Nagler B. Studies on the natural history of multiple sclerosis. 3. Epidemiologic analysis of the army experience in World War II. Neurology 1967; 17: 1–17
  • Birk K., Rudick R. Pregnancy and multiple sclerosis. Archives of Neurology 1986; 43: 719–726
  • Cernacek A. J. Navrh koncepce perspektiniho rozvoje neurologie v CCSR. Ceskoslovenka Neu-rologie 1971; 34: 167–174
  • Chiba M., Yamada M. About calcification of the pineal gland in Japanese. Foliopsychiatry Neurology Japan 1948; 2: 301–303
  • Cottrell S. S., Wilson S. A. K. The affective symptomatology of disseminated sclerosis: a study of 100 cases. Journal of Neurology and Psychopathology 1929; 7: 1–30
  • Cremer-Bartels G., Krause K., Kuechle H. J. Influence of low magnetic field-strength variations on the retina and pineal gland of quails and humans. Graefe's Archives of Clinical and Experimental Ophthalmology 1983; 220: 248–252
  • Dalos N. P., Rabins P. V., Brooks B. R. Disease activity and emotional state in multiple sclerosis. Annals of Neurology 1983; 13: 573–577
  • Daramola G. F., Olowu A. O. Physiological and radiological implications of a low incidence of pineal calcification in nigeria. Neuroendocrinology 1972; 9: 41–57
  • Datta P. C., King M. G. Melatonin: effects on brain and behavior. Neuroscience & Bio-behavioral Reviews 1980; 4: 451–458
  • Dean G. Annual incidence, prevalence and mortality of multiple sclerosis in white South African-born and in white immigrants to South Africa. British Medical Journal 1967; 2: 724–730
  • Demaine C., Semm P. The avian pineal gland as an independent magnetic sensor. Neuroscience Letters 1985; 62: 119–122
  • Dyke C. G. Indirect signs of brain tumor as noted in routine roentgen examinations: Displacement of the pineal shadow: A survey of 3,000 consecutive skull examinations. American Journal of Radiology 1930; 23: 598–606
  • Ebadi M. Regulation of the synthesis of melatonin and its significance to neuroendocrinology. The pineal gland, R. J. Reiter. Raven Press, New York 1984; 1–37
  • Ebers G.C, Bulman D. E. Sadovnik. A population based study of multiple sclerosis in twins. New England Journal of Medicine 1986; 318: 1638–1642
  • Erlich S. S., Apuzzo M. L. J. The pineal gland: anatomy, physiology, and clinical significance. Journal of Neurosurgery 1985; 63: 321–341
  • Francis D. A., Batchelor J. R., MacDonald W. I. Multiple sclerosis in northeast Scotland. Brain 1987; 110: 181–196
  • Freeman W. Treatment with special reference to fever therapy prolonged rest and diamato-therapy. Medical Annals of the District of Columbia 1944; 13: 58–67
  • Hippocrates. Aphorisms. IV Hippocrates, W. H. S. Jones. University Press, Cambridge 1959
  • Hughes R. A. C. Prospects for the treatment of multiple sclerosis. Journal of the Royal Society of Medicine 1991; 84: 63–65
  • Hyyppa M. T., Jolma T., Riekkinen P., Rinne U. K. Effects of L-tryptophan on central indoleamine metabolism and short-lasting neurologic disturbances in multiple sclerosis. Journal of Neural Transmission 1975; 37: 297–304
  • Jankovic B. D., Isakovic K., Petrovic S. Effect of pinealectomy on immune reactions in the rat. Immunology 1970; 18: 1–5
  • Joffe R. T., Lippert G. P., Gray T. A. Mood disorder and multiple sclerosis. Archives of Neurology 1987; 44: 376–378
  • Johansson B., Roos B. E. 5-hydroxyindoleacetic acid in cerebrospinal fluid of patients with neurological diseases. European Neurology 1974; 11: 37–45
  • Johnson R. T. Viral aspects of multiple sclerosis. Handbook of clinical neurology, demyelinating diseases, P. J. Vinken, G. W. Bruyn, H. L. Klawans, J. C. Koetsier. Elsevier, Amsterdam 1985; 319–336
  • Kellner C. H., Davenport Y., Post R. M., Ross R. J. Rapidly cycling bipolar disorder and multiple sclerosis. American Journal of Psychiatry 1984; 141: 112–113
  • Koprowski H., DeFreitas E. C., Harper M. E. Multiple sclerosis and human T cell lym-photropic retroviruses. Nature 1985; 318: 154–160
  • Kripke D. F., Gillin J. C., Mullaney D. J. Treatment of major depressive disorders by bright white light for five years. Chronobiology and neuropsychiatry disorders, A. Halaris. Elsevier, New York 1987
  • Kumar M. S. A., Chen C. L., Sharp D.C, Liu J. M., Kalra P. S., Kalra S. P. Diurnal fluctuations in methionine-enkephalin levels in the hypothalamus and preoptic area of the male rat: effects of pinealectomy. Neuroendocrinology 1982; 35: 28–31
  • Kurtzke J. F. A reassessment of the distribution of multiple sclerosis. Part one, part two. Acta Neurologica Scandinavica 1975; 51: 110–136
  • Kurtzke J. F. The geographic distribution of multiple sclerosis: an update with special reference to Europe and the Mediterranean region. Acta Neurologica Scandinavica 1980; 62: 62–80
  • Kurtzke J. F., Beebe G. W., Norman J. E. Epidemiology of multiple sclerosis in US veterans I. Race, sex, and geographic distribution. Neurology 1979; 29: 1228–1235
  • Lewy A. J., Sack R. L. Phase typing and bright light therapy of chronobiologic sleep and mood disorders. Chronobiology and psychiatric disorders, A. Halaris. Elsevier, New York 1987; 181–206
  • Lewy A. J., Wehr T. A., Goodwin F. K., Newsome D. A., Rosenthal N. E. Manic depressive patients may be supersensitive to light. Lancet 1981; 1: 383–384
  • Lewy A. J., Nurnberger J. I., Wehr T. A., Pack D., Becker L. E., Powell R. L., Newsome D. A. Supersensitivity to light: Possible trait marker for manic depressive illness. American Journal of Psychiatry 1985; 142: 725–727
  • Limburg C. C. The geographic distribution of multiple sclerosis and its estimated prevalence in the U.S. Proceedings of the Association for Research in Nervous and Mental Diseases 1950; 28: 15–24
  • Lindstedt M. Multiple sclerosis-is research on the wrong track. Medical Hypotheses 1991; 34: 69–72
  • Maestroni G. J. M., Conti A., Pierpaoli W. The pineal gland and the circadian, opiatergic, immunoregulatory role of melatonin. Annals of the New York Academy of Science 1987a; 496: 67–77
  • Maestroni G. J. M., Conti A., Pierpaoli W. Melatonin counteracts the effect of acute stress on the immune system via an opiatergic system. Fundamentals and clinics in pineal research, G. P. Trentini, C. De Gaetani, P. Pevet. Raven Press, New York 1987b; vol. 44: 277–279
  • Maestroni G. J. M., Conti A., Pierpaoli W. Role of the pineal gland in immunity. Ill: Melatonin antagonizes the immunosuppressive effect of acute stress via an opiatergic mechanism. Immunology 1988; 63: 465–469
  • Matthews W. B., Acheson E. D., Batchelor J. R., Weller R. O. McAlpines multiple sclerosis. Churchill Livingstone, Edinburgh 1985
  • McDonald W. I. The mystery of the origin of multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry 1986; 49: 113–123
  • McFarlin D. E., McFarland H. Multiple sclerosis. New England Journal of Medicine 1982; 307: 1183–1188
  • McLvor G. P., Riklan M., Reznikoff M. Depression in multiple sclerosis as a function of length and severity of illness, age, remission and perceived social support. Journal of Clinical Psychology 1984; 40: 1028–1033
  • Miles A., Philbrick D. R. S. Melatonin and psychiatry. Biological Psychiatry 1988; 23: 405–425
  • Mohr J. P. Multiple sclerosis. Manual of clinical problems in neurology, J. P. Mohr. Little Brown, Boston 1984; 273–277
  • Monaco F., Fumcro S., Mondino A., Mutani R. Plasma and cerebrospinal fluid tryptophan in multiple sclerosis and degenerative diseases. Journal of Neurology, Neurosurgery and Psychiatry 1979; 42: 640–641
  • Norman J. E., Kurtzke J. F., Beebe G. W. Epidemiology of multiple sclerosis in US veterans 2. Latitude, climate and the risk of multiple sclerosis. Journal of Chronic Disease 1983; 36: 551–560
  • Oksenberg J. R., Mantegazza R., Sakai K., Bernard C. C. A., Steinman L. HTLV-1 sequences are not detected in peripheral blood genomic DNA or in brain cDNA of multiple sclerosis patients. Annals of Neurology 1990; 28: 574–577
  • Olcese J., Reuss S. Magnetic field effects on pineal gland melatonin synthesis: comparative studies on albino and pigmented rodents. Brain Research 1986; 369: 365–368
  • O'Reilly M. A. R., O'Reilly P. M. R. Temporal influences on relapses of multiple sclerosis. European Neurology 1991; 31: 391–395
  • Parry B. L., Berga S. L., Mostofi N., Sependa P. A., Kripke D. F., Gillin J. C. Morning versus evening bright light treatment of late luteal phase dysphoric disorder. American Journal of Psychiatry 1987; 146: 1215–1217
  • Pierpaoli W., Maestroni G. J. M. Neuroimmunomodulation: some recent views and findings. International Journal of Neuroscience 1988; 39: 165–175
  • Pierpaoli W., Yi C. The involvement of pineal gland and melatonin in immunity and aging. I. Thymus-mediated, immunoreconstituting and antiviral activity of thyrotropin-releasing hormone. Journal of Neuroimmunology 1990; 27: 99–109
  • Poskanzer D.C, Terasaki P. I., Prenney L. B., Sheridan J. L., Park M. S. Multiple sclerosis in the Orkney and Shetland Islands. 3: Histocompatibility determinants. Journal of Epidemiology and Community Health 1980; 34: 253–257
  • Prineas J. W. The etiology and pathogenesis of multiple sclerosis. Multiple sclerosis and other demyelinating diseases, P. J. Vinken, G. W. Bruyn. North Holland, Amsterdam 1970; 107–160
  • Ralph C. L. Pineal bodies and thermoregulation. The pineal gland, R. J. Rciter. Raven Press, New York 1978; 193–219
  • Rella W., Lapin V. Immunocompetence of pinealectomized and simulateneously pinealec-tomized and thymectomized rats. Oncology 1976; 33: 3–6
  • Relkin R., Schneck L. Effects of pinealectomy on rat brain myelin. Proceedings of the Society for Experimental Biology and Medicine 1975; 148: 337–338
  • Relkin R., Fok W. Y., Schneck L. Pinealectomy and brain myelination. Endocrinology 1973; 92: 1426–1428
  • Romijn H. J. The pineal, a tranquillizing organ. Life Sciences 1978; 23: 2257–2274
  • Rosenstein R. E., Cardinali D. P. Melatonin increases in vivo GABA accumulation in rat hypothalamus, cerebellum, cerebral cortex and the pineal gland. Brain Research 1985; 398: 403–406
  • Rosenthal N. E., Sack D. A., Carpenter C. J., Parry B., Mendelson W. B., Wehr T. A. Antidepressant effects of light in seasonal affective disorder. American Journal of Psychiatry 1986; 142: 163–170
  • Rozencwaig R., Grad B. R., Ochota J. The role of melatonin and serotonin in aging. Medical Hypotheses 1987; 23: 337–352
  • Rudolph K., Wirz-Justice A., Krauchi K., Feer H. Static magnetic fields decrease nocturnal pineal cAMP in the rat. Brain Research 1988; 446: 159–160
  • Sandyk R. The pineal gland and the clinical course of multiple sclerosis. International Journal of Neuroscience 1992; 62: 65–74
  • Sandyk R., Awerbuch G. I. The pineal gland in multiple sclerosis. International Journal of Neuroscience 1991; 61: 61–67
  • Schiffer R. B. The spectrum of depression in multiple sclerosis. An approach for clinical management. Archives of Neurology 1987; 44: 596–599
  • Schiffer R. B., Babigian H. M. Behavioral disorders in multiple sclerosis, temporal lobe epilepsy, and amyotrophic lateral sclerosis: an epidemiologic study. Archives of Neurology 1984; 41: 1067–1069
  • Schiffer R. B., Caine E. D., Bamford K. A. Depressive episodes in patients with multiple sclerosis. American Journal of Psychiatry 1983; 140: 1498–1500
  • Schiffer R. B., Wineman N. M., Weitkamp L. R. Association between bipolar affective disorder and multiple sclerosis. American Journal of Psychiatry 1986; 143: 94–95
  • Semm P. Neurobiological investigations on the magnetic sensitivity of the pineal gland in rodents and pigeons. Comparative Biochemistry and Physiology 1983; 76A: 683–689
  • Shibasaki H. Clinical and epidemiological aspects of multiple sclerosis in Asia. Progress in Clinical Neurosciences 1985; 2: 56–64
  • Sibley W. A., Foley J. M. Seasonal variation in multiple sclerosis and retrobulbar neuritis in northeastern ohio. Transmission of the American Neurological Association 1965; 90: 295–297
  • Sibley W. A., Paty D. W. A comparison of multiple sclerosis in Arizona (USA) and Ontario (Canada)–preliminary report. Acta Neurologica Scandinavica (suppl 87) 1981; 64: 60–65
  • Skegg D. C. G. Multiple sclerosis: nature or nurture. British Medical Journal 1991; 320: 247–248
  • Sonninen V., Riekkinen P., Rinne U. K. Acid monoamine metabolites in cerebrospinal fluid in multiple sclerosis. Neurology 1973; 23: 760–763
  • Spielman R. S., Nathanson N. The genetics of susceptibility to multiple sclerosis. Epidemiological Reviews 1982; 4: 45–65
  • Stehle J., Reuss S., Vollrath L. Electrophysiological characterization of the pineal gland of golden hamsters. Experimental Brain Research 1987; 67: 27–32
  • Surridge D. An investigation into some aspects of multiple sclerosis. British Journal of Psychiatry 1969; 115: 149–164
  • Swingler R. J., Compston D. A. S. The distribution of multiple sclerosis in Britain. Journal of Neurology, Neurosurgery and Psychiatry 1986; 49: 1115–1124
  • Taub R. G., Rucker C. W. The relationship of retrobulbar neuritis to multiple sclerosis. American Journal of Opthalmology 1954; 37: 494–497
  • Thompson C, Stinson D., Smith A. Seasonal affective disorder and season-dependent abnormalities of melatonin suppression by light. Lancet 1990; 336: 703–706
  • Vogel G. W. Evidence for REM sleep deprivation as the mechanism of action of antidepressant drugs. Progress in Neuropsychopharmacology & Biological Psychiatry 1983; 7: 343–349
  • Wehr T. A., Goodwin F. K. Circadian rhythm desynchronization as a basis for manic-depressive cycles. Psychopharmacology Bulletin 1980; 16: 19–20
  • Wehr T. A., Rosenthal N. E. Seasonality and affective illness. American Journal of Psychiatry 1989; 146: 829–839
  • Welker H. A., Semm P., Willig R. P., Commentz J.C, Wiltschko W., Vollrath L. Effects of an artificial magnetic field on serotonin N-acetyltransferase activity and melatonin content of the rat pineal gland. Experimental Brain Research 1983; 50: 426–432
  • Wever R. Einfluss Schwacher Elektro-magnetischer Felder auf die Circadiane Periodik des Menschen. Naturwissenschaften 1968; 55: 29–32
  • Whitlock F. A., Siskind M. M. Depression as a major symptom of multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry 1980; 43: 861–865
  • Wuetrich R., Rieder H. P. The seasonal incidence of multiple sclerosis in Switzerland. European Neurology 1970; 3: 257–264
  • Zeigler L. H. Multiple sclerosis: a clinical review and follow-up study. Minnesota Medicine 1929; 12: 778–783

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