10
Views
3
CrossRef citations to date
0
Altmetric
Original Article

Sialic Acid and Epithelial Differentiation in Colorectal Polyps and Cancer – A Morphological, Mucin and Lectin Histochemical Study

&
Pages 233-242 | Accepted 20 Jul 1992, Published online: 06 Jul 2009

References

  • Culling C FA, Reid PE., Worth A J, Dunn W L. A new histochem-ical technique of use in the interpretation and diagnosis of adenocarcinoma and villous lesions in the large intestine. J Clin Pathol 1977; 30: 1056–62
  • Reid P E, Culling C FA, Dunn W L. Differences between the O-acetylated sialic acids of the epithelial mucins of human colonic tumours and normal controls: A correlative chemical and histochemical study. J Histochem Cytochem 1980; 28: 217–22
  • Cooper H S. Peanut lectin binding sites in large bowel carcinoma. Lab Invest 1982; 47: 383–90
  • Cooper H S, Reuter V E. Peanut lectin-binding sites in polyps of the colon and rectum. Lab Invest 1983; 49: 655–61
  • Greaves P, Filipe M I, Abbas S, Ormerod M G. Sialomucins and carcinoembryonic antigen in the evolution of colorectal cancer. Histopathology 1984; 8: 825–34
  • Eide T J, Nielsen K, Solberg S. Dysplasia in colorectal adenomas related to the presence of O-acetylated sialic mucin and to morpho-metric measurements. Acta Pathol Microbiol Scand (Sect A) 1987; 95: 365–9
  • Agawa S, Jass J R. Sialic acid histochemistry and the adenoma-carcinoma sequence in colorectum. J Clin Pathol 1990; 43: 528–32
  • Sugihara K, Jass J R. Colorectal goblet cell sialomucin heterogeneity: its relation to malignant disease. J Clin Pathol 1986; 39: 1088–95
  • Jass J R, England J, Miller K. Value of mucin histochemistry in follow up surveillance of patients with long standing ulcerative colitis. J Clin Pathol 1986; 39: 393–8
  • Agawa S, Muto T, Morioka Y. Mucin abnormality of colonic mucosa in ulcerative colitis associated with carcinoma and/or dysplasia. Dis Colon Rectum 1988; 31: 387–9
  • Jass J R, Sugihara K, Love S B. Basis of sialic acid heterogeneity in ulcerative colitis. J Clin Pathol 1988; 41: 388–92
  • Jass J R, Ml Filipe, Abbas E. A morphologic and histochem-ical study of metaplastic polyps of the colorectum. Cancer 1984; 53: 510–5
  • Lance P, Lev R. Colonic oligosaccharide structures deduced from lectin-binding before and after desialylation. Hum Pathol 1991; 22: 307–12
  • Leathern A, Atkins N. Lectin binding to formalin-fixed paraffin sections. J Clin Pathol 1983; 36: 747–50
  • Veh R W, Meessen D, Kuntz D, May B. Colonic carcinogenesis, RA Malt, RCN Williamson. MTP Press Ltd, Lancaster 1982; 355–65
  • Lotan R, Skutelsky E, Danon D, Sharon N. The purification composition and specificity of the anti-T lectin from peanut (Arachis hypogaea). J Biol Chem 1875; 250: 8518–23
  • Picard J K, Feizi T. Peanut lectin and anti-li antibodies reveal structural differences among human gastrointestinal glycoproteins. Mol Immunol 1983; 20: 1215–20
  • Ørntoft T F, Harving N, Langkilde N C. O-linked mucin-type glycoproteins in normal and malignant colon mucosa: lack of T-antigen expression and accumulation of Tn and sialosyl-Tn antigens in carcinomas. Int J Cancer 1990; 45: 666–72
  • Sata T, Roth J, Zuber C. Studies on the Thomsen-Friedenreich antigen in human colon with the lectin Amaranthin. Normal and neoplastic epithelium express only cryptic T antigen. Lab Invest 1992; 66: 175–86
  • Richman P I, Bodmer W F. Monoclonal antibodies to human colorectal epithelium: markers for differentiation and tumour characterisation. Int J Cancer 1987; 39: 317–28
  • Hughes N R, Newland R C. Colorectal polyps in an Australian population. A histological and immunohistochemical study. J Pathol 1990; 160: 41–50
  • Hanksi C, Bornhoeft G, Topf N, Hermann U, Stein H, Riecken E O. Detection of a mucin marker for the adenoma-carcinoma sequence in human colonic mucosa by monoclonal antibody AM-3. J Clin Pathol 1990; 43: 379–84
  • Fuller C E, Davies R P, Williams G T, Williams E D. Crypt restricted loss of sialomucin O-acetylation in the human colon – a marker of somatic mutation. J Pathol 1989; 157: 174A
  • Ørntoft T F, Langkilde N C, Wiener H, Ottosen P D. Cellular localization of PNA binding in colorectal adenomas: Comparison with differentiation nuclear: cell height ratio and effect of desialylation. APMIS 1991; 99: 275–81
  • Boland C R, Montgomery C K, Kim Y S. A cancer-associated mucin alteration in benign colonic polyps. Gastroenterology 1982; 82: 664–72
  • Boland C R, Montgomery C K, Kim Y S. Alterations in human colonic mucin occurring with cellular differentiation and malignant transformation. Proc Natl Acad Sci 1982; 79: 2051–5
  • Quincey C, Raitt N, Bell J, Ellis I O. Intracytoplasmic lumina – a useful diagnostic feature of adenocarcinoma. Histopathology 1991; 19: 83–7
  • Longacre T A, Fenoglio-Preiser C M. Mixed hyperplastic adenomatous polyps/serrated adenomas. A distinct form of colorectal neoplasia. Am J Surg Pathol 1990; 14: 524–37
  • Feizi T, Gooi H C, Childs R A. Tumour-associated and differentiation antigens on the carbohydrate moieties of mucin-type glycoproteins. Biochem Soc Trans 1984; 12: 591–6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.