Effect of loss of regional fat assessed by DXA on insulin resistance and dyslipidaemia in obese men

References

• Bjørntorp P. Metabolic implications of body fat distribution. Diabetes Care 1991;14:1132–43.
   PubMed Web of Science ®Google Scholar
• Despres J-P. Abdominal obesity as important component of insulin resistance syndrome. Nutrition 1993;9:452–9.
   PubMed Web of Science ®Google Scholar
• Tankó LB, Bagger YZ, Alexandersen P, Larsen PJ, Christiansen C. Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women. Circulation 2003;107:1626–31.
   PubMed Web of Science ®Google Scholar
• Williams MJ, Hunter GR, Kekes-Szabo T, Snyder S, Treuth MS. Regional fat distribution in women and risk of cardiovascular disease. Am J Clin Nutr 1997;65:855–60.
   PubMed Web of Science ®Google Scholar
• Van Pelt RE, Evans EM, Schechtman KB, Ehsani AA, Kohrt WM. Contribution of total and regional fat mass to risk for cardiovascular disease in older women. Am J Physiol Endocrinol Metab 2002;282:E1023–E28.
   PubMed Web of Science ®Google Scholar
• Tatsukawa M, Kurokawa M, Tamari Y, Yoshimatsu H, Sakata T. Regional fat deposition in the legs is useful as a presumptive marker of antiatherogenesity in Japanese. Proc Soc Exp Bio Med 2000;223:156–62.
   PubMed Web of Science ®Google Scholar
• Snijder MB, Dekker JM, Visser M, Bouter LM, Stehouwer CD, Yudkin JS, Heine RJ, Nijpels G, Seidell JC. Trunk fat and leg fat have independent and opposite associations with fasting and postload glucose levels. Diabetes Care 2004;27:372–7.
   PubMed Web of Science ®Google Scholar
• Goodpaster BH, Kelley DE, Wing RR, Meier A, Thaete L. Effects of weight loss on regional fat distribution and insulin sensitivity in obesity. Diabetes 1999;48:839–47.
   PubMed Web of Science ®Google Scholar
• Abate N, Garg A, Peshock RM, Stray-Gundersen J, Grundy SM. Relationship of generalized and regional adiposity to insulin sensitivity in men. J Clin Invest 95;96:88–98.
   Google Scholar
• Aasen G, Fagertun H, Halse J. Regional fat mass by DXA: high leg fat mass attenuates the relative risk of insulin resistance and dyslipidaemia in obese but not in overweight postmenopausal women. Scand J Clin Lab Invest 2008; 68:204–11.
   PubMed Web of Science ®Google Scholar
• Paradisi G, Smith L, Burtner C, Leaming R, Garvey WT, Hook G, Johnson A, Cronin J, Steinberg HO, Baron AD. Dual energy X-ray absorptiometry assessment of fat mass distribution and its association with the insulin resistance syndrome. Diabetes Care 1999;22:1310–7.
   PubMed Web of Science ®Google Scholar
• Aasen G, Fagertun H, Halse J. Leg fat mass measured by dual X-ray absorptiometry (DXA) impacts insulin resistance differently in obese women versus men. Scand J Clin Lab Invest 2009:69:181–9.
   PubMed Web of Science ®Google Scholar
• Colman E, Katzel LI, Rogus E, Coon P, Muller D, Goldberg AP. Weight loss reduces abdominal fat and improves insulin action in middle-aged and older men with impaired glucose tolerance. Metabolism 1995;44:1502–8.
   PubMedGoogle Scholar
• Katzel LI, Bleeker ER, Colman EG, Rogus EM, Sorkin JD, Goldberg AP. Effects of weight loss vs. aerobic exercise training on risk factors for coronary disease in healthy, obese middle-aged and older men: a randomised controlled trial. JAMA 1995;274:1915–21.
   PubMed Web of Science ®Google Scholar
• Rosenfalck AM, Hendel H, Rasmussen MH, Almdal T, Anderson T, Madsbad S. Minor long-term changes in weight have beneficial effect on sensitivity and beta-cell function in obese subjects. Diabetes Obes Metab 2002;4:19–28.
   PubMedGoogle Scholar
• Cornier MA, Donahoo WT, Pereira R, Gurevich I, Westergren R, Enerback S, Eckel PJ, Goalstone ML, Hill JO, Eckel RH, Draznin B. Insulin sensitivity determines the effectiveness of dietary macronutrient composition on weight loss in obese women. Obes Res 2005;13:703–9.
   PubMedGoogle Scholar
• McLaughlin T, Abbasi F, Carantoni M, Schaaf P, Reaven G. Differences in insulin resistance do not predict weight loss in response to hypocaloric diets in healthy obese women. J Clin Endocrinol Metab 1999;84:578–81.
   PubMed Web of Science ®Google Scholar
• De Luis DA, Aller R, Izaola O, Gonzales SM, Conde R. Differences in glycaemic status do not predict weight loss in response to hypocaloric diets in obese patients. Clin Nutr 2006;25:117–22.
   PubMedGoogle Scholar
• Aasen G, Fagertun H, Halse J. Body composition analysis by dual X-ray absorptiometry: in vivo and in vitro comparison of three different fan-beam instruments. Scand J Clin Lab invest 2006;66:659–66.
   PubMed Web of Science ®Google Scholar
• Aasen G, Fagertun H, Halse J. Effect of regional fat loss assessed by DXA on insulin resistance and dyslipidaemia in obese women. Scand J Clin Lab Invest 2010;70:229–236.
   PubMed Web of Science ®Google Scholar
• Matthews DR, Hosker JP, Rudenski AS, Maylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28: 412–19.
   PubMed Web of Science ®Google Scholar
• Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggianai F, Zenner MB, Monauni T, Muggero M. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity. Diabetes Care 2000;23:57–63.
   PubMed Web of Science ®Google Scholar
• Katz A, Nambi SS, Mather K, Baron AD, Follman DA, Sullivan G, Quon MJ. Quantitative insulin sensitivity check index: a simple accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000; 85:2402–10.
   PubMed Web of Science ®Google Scholar
• Yokoyama H, Emoto M, Fujiwara S, Motomyama K, Morioka T, Komatsu M, Tahara H, Shoji T, Nishizawa Y. Quantitative insulin sensitivity check index and the reciprocal index of homeostasis model assessment in normal weight range and moderately obese type 2 diabetic patients. Diabetes Care 2003;26:426–32.
   Web of Science ®Google Scholar
• Friedewald WR, Levy RI, Fredichson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 1972;18:499–502.
   PubMed Web of Science ®Google Scholar
• Chaston TB, Dixon JB. Factors associated with per cent change in visceral versus subcutaneous abdominal fat tissue during weight loss: findings from a systematic review. Int J Obes (Lond) 2008;32:619–28.
   PubMed Web of Science ®Google Scholar
• Janssen I, Ross R. Effects of sex on the changes in visceral, subcutaneous adipose tissue and skeletal muscle in response to weight loss. Int J Obes Relat Metab Disord 1999;23: 1035–46.
   PubMed Web of Science ®Google Scholar
• Doucet E, St-Pierre S, Almeras N, Imbeault P, Mauriege P, Pascot A, Despres J-P Tremblay A. Reduction of visceral adipose tissue during weight loss. Eur J Clin Nutr 2002;56: 297–303.
   PubMedGoogle Scholar
• Kuk JL, Ross R. Influence of sex on total and regional fat loss in overweight and obese men and women. Int J Obes 2009;33:629–34.
   PubMed Web of Science ®Google Scholar
• Buemann B, Sørensen TIA, Pedersen O, Black E, Holst C, Toubro S, Echwald S, JJ Holst, Rasmussen C, Astrup A. Lower-body fat mass as an independent marker of insulin sensitivity – the role of adiponectin. Int J Obes 2005;29: 624–31.
   Google Scholar
• Kopp HP, Krzyzanowska K, Mohlig M, Spranger J, Pfiffer AF, Schernthaner G, Effects of marked weight loss on plasma levels of adiponectin, markers of chronic subclinical inflammation and insulin resistance in morbidly obese women. Int J Obes (Lond) 2005;29:766–71.
   PubMed Web of Science ®Google Scholar
• Abbasi F, Lamendola C, Mc Laughlin T, Hayden J, Reaven GM, Reaven PD. Plasma adiponectin concentrations do not increase in association with moderate weight loss in insulin-resistant, obese women. Metabolism 2004;53:280–3.
   Google Scholar
• Keogh JB, Brinkworth GD, Noakes N, Belobrajdic DP, Buckley JD, Clifton PM. Effects of weight loss from a very-low-carbohydrate diet on endothelial function and markers of cardiovascular disease risk in subjects with abdominal obesity. Am J Clin Nutr 2008;87:567–76.
   PubMed Web of Science ®Google Scholar
• Keogh JB, Brinkworth GD, Clifton PM. Effects of weight loss on a low-carbohydrate diet on flow-mediated dilatation, adhesion molecules and adiponectin. Br J Nutr 2007;29: 852–9.
   Google Scholar
• Madsen EL, Rissanen A, Bruun JM, Skogstrand K, Tonstad S, Hougaard DM, Richelsen B. Weight loss larger than 10% may be needed for general improvement of circulating levels of adiponectin and markers of inflammation in obese subjects: a 3- year weight loss study. Eur J Endocrinol 2008; 158:179–187.
   PubMed Web of Science ®Google Scholar
• Marcovic TP, Campbell LV, Balasubramanian S, Jenkins A, Fleury AC, Simons LA, Chrisholm DJ. Beneficial effect on average lipid levels from energy restriction and fat loss in obese individuals with or without type 2 diabetes. Diabetes Care 1998;21:695–700.
   PubMedGoogle Scholar
• Muscelli E, Camastra S, Catalano C, Q Galvan, Ciociaro D, Baldi S, Ferrannini E. Metabolic and cardiovascular assessment in moderate obesity: effect of weight loss. J Clin Endocrinol Metab 1997;82:2937–43.
   PubMed Web of Science ®Google Scholar
• Ditschuneit HH, Fletcher-Mors M, Johnson TD, Adler G. Metabolic and weight-loss effects of a long-term dietary intervention in obese patients. Am J Clin Nutr 1999;69:198–204.
   PubMed Web of Science ®Google Scholar
• Nordmann AJ, Nordmann A, Briel M, Keller U, Yancy WS, Brehm BJ, Bucher HC. Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors. A meta-analyses of randomized controlled trials. Arch Int Med 2006:166;285–93.
   PubMed Web of Science ®Google Scholar
• Kelley GA. Kelley KS, Vu Tran Z. Aerobic exercise, lipids and lipoproteins in overweight and obese adults: a meta-analysis of randomized controlled trials. Int J Obes (Lond), 2005;29:881–93.
   PubMed Web of Science ®Google Scholar
• Kuk J, Kilpatrick K, Davidson LE, Hudson R, Ross R. Whole-body skeletal muscle mass is not related to glucose tolerance or insulin sensitivity in overweight and obese men and women. Appl Physiol Nutr Metab 2008;33:769–74.
   PubMed Web of Science ®Google Scholar
• Douketis JD, Macie C, Thabane L, Williamson DF. Systematic review of long-term weight loss studies in obese adults: clinical significance and applicability to clinical practice. Int J Obes (Lond) 2005;29:1153–67.
   PubMed Web of Science ®Google Scholar
• Hanley AJG, Williams K, Stern MP, Haffner SM. Homeostasis model assessment of insulin resistance of cardiovascular disease. The San Antonio Heart Study. Diabetes Care 2002;25: 1177–84.
   PubMed Web of Science ®Google Scholar