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Research Article

Key questions in Vitamin D research

Pages 154-162 | Published online: 26 Apr 2012

References

  • Institute of Medicine. Dietary reference intakes for calcium and Vitamin D. Ross AC, Taylor CL, Yaktine AL, Del Vale HB (eds). National Academies Press, Washington DC. 2011.
  • Cranney A, Horsley T, O'Donnell S, Weiler H, Puil L, Ooi D, Atkinson S, Ward L, Moher D, Hanley D, Fang M, Yazdi F, Garritty C, Sampson M, Barrowman N, Tsertsvadze A, Mamaladze V. Effectiveness and safety of vitamin d in relation ot bone health. Evidence report/technology/assessment no 158. AHRQ publication no -7-EO13. Rockville, MD: Agency for Healthcare Research and Quality, 2007. Internet: http://www.ahrq.gov/downloads/pub/evidence/pdf/vitamind/vitad.pdf (accessed 2/20/2012).
  • Brannon PM, Yetley EA, Regan BL, Picciano MF. Summary of roundtable discussion on vitamin D research needs. Am J Clin Nutr 2008;88(suppl):587S–592S.
  • Brannon PM, Picciano MF. Vitamin D in pregnancy and lactation in humans. Annu Rev Nutr 2011; 21;31:89–115.
  • Cashman KD, Kiely, M. Towards prevention of vitamin D deficiency and beyond: knowledge gaps and research needs in vitamin D nutrition and public health. Br J Nutr 2011;106:1617–1627.
  • Chung M, Balk EM, Brendel M, Ip S, Lau J, Lee J, Lichtenstein A, Patel K, Raman G, Tatsioni A, Terasawa T, Trikalinos TA. Vitamin D and calcium: a systematic review of health outcomes. Evidence Report No. 183. (Prepared by the Tufts Evidence-based Practice Center under Contract No. HHSA 290–2007–10055-I.) AHRQ Publication No. 09-E015. Rockville, MD: Agency for Healthcare Research and Quality. August, 2009. Internet: http://www.ahrq.gov/downloads/pub/evidence/pdf/vitadcal/vitadcal.pdf (accessed 2/20/2012).
  • Brannon PM, Yetley, EA, Bailey RL, Picciano MF. Overview of the conference “Vitamin D and Health in the 21st Centurey: An Update.” Am J Clin Nutr 2008;88(suppl): 483S–90S.
  • Chun RF, Lauridsen AL, Suon L, Zella LA, Pike JW, Modlin RL, Marineau AR, Wilkinson RJ, Adams J, Hewison M. Vitamin D binding protein directs moncyte responses to 25hydroxy- and 1,25-dihydroxyvitamin D. J Clin Endocrinol Metab 2010;95:3368–3376.
  • Willnow TE, Nykiaer A. Cellular uptake of steroid carrier proteins- mechanisms and implications. Mol Cell Endocrinol 2010;316:93–102.
  • Esteban C, Genakens M, Ena JM, Mishal Z, Machot A, Torres JM, Uriel J. Receptor-mediated uptake and processing of vitamin D binding protein in human B-lymphoid cells. J Biol Chem 1992;267:10177–83.
  • Rowling MJ, Kemmis CM, Taffany DA, Welsh J. Megalin-mediated endocytosis of vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells. J Nutr 2006;136:2754–60.
  • Gressner OA, Lahme B, Gressner AM. Gc-globulin (vitamin D binding protein) is synthesized and secreted by hepatocytes and internalized by hepatic stellate cells through Ca(2 +)-dependent interaction with the megalin/gp330 receptor. Clin Chim Acta 2008;390(1–2):28–37.
  • Atkins GJ, Anderson PH, Findlay DM, Welldon KJ, Vincent C, Zannettino AC, O'Loughlin PD, Morris HA. Metabolism of vitamin D3 in human osteoblasts: evidence for autocrine and paracrine activities of 1 alpha,25-dihydroxyvitamin D3. Bone 2007;40(6):1517–28.
  • Weinstein SJ, Stolzenberg-Solomog RZ, Kopp W, Rager H, Virtano J, Allbanes D. Impact of circulating vitamin D binding protein levels on the association between 25-hydroxyvitamin D and pancreatic cancer risk: a nested case-control study. Cancer Res 2012;72:1–9.
  • Cashman KD, Fitzgerald AP, Kiely M, Seamans KM. A systematic review and meta-regression analysis of the vitamin D intake-serum 25-hydroxyvitamin D relationship to inform European recommendations. Br J Nutr 2011; 106(11):1638–48.
  • Gallagher JC, Sai A, Templin T 2nd, Smith L. Dose response to vitamin d supplementation in postmenopausal women: a randomized trial. Ann Intern Med 2012;156:425–437.
  • Hollis BW, Johnson D, Hulsey TC, Ebeling M, Wagner CL. Vitamin D supplementation during pregnancy: Double blind, randomized clinical trial of safety and effectiveness. J Bone Miner Res 2011;18(6):371–5.
  • Wagner D, Hanwell HE, Schnabl K, Yazdanpanah M, Kimball S, Fu L, Sidhom G, Rousseau D, Cole DE, Vieth R. The ratio of serum 24,25-dihydroxyvitamin D(3) to 25-hydroxyvitamin D(3) is predictive of 25-hydroxyvitamin D(3) response to vitamin D(3) supplementation. J Steroid Biochem Mol Biol 2011;126:72–7.
  • Farrell CJ, Martin S, McWhinney B, Straub I, Williams P, Hermann M. State of the art vitamin D assays: a comparison of automated immunoassays with liquid chromatography tandem mass spectrometry methods. Clin Chem 2012; 58:531–42.
  • Mann HW, Cho JH, Hur M, Song J, Oh GY, P CM, Yun YM, Kim JQ. Comparison of four current 25-hydroxyvitamin D assays. Clin Biochem 2012;45:326–30.
  • Heijboer AC, Blankenstein MA, Kema IP, Buijs MM. Accuracy of 6 routine 25-hydroxyvitamin D assays influence: influence of vitamin D binding protein concentration. Clin Chem 2012;58:543–8.
  • McGrath JJ, Saba S, Burne THH, Eyles DW. A systematic review of the associationbetween common single nucleotide polymorphisms and 25-hydroxyvitamin D concentrations. J Steroid Biochem Mol Biol 2010;471–477.
  • Hibler EA, Hu C, Jurutka PW, Martinez ME, Jacobs ET. Polymorphic variation in the GC and CASR Genes and associations with vitamin D metabolite concentration and, metachronous colorectal neoplasia. Cancer Epidemiol Biomarkers Prev 2012;21:368–75.
  • Bu FX, Armas L, Lappe J, Zhou Y, Gao G, Wang HW, Recker R, Zhan LJ. Comprehensive association analysis of nine candidate genes with serum 25-hydroxy vitamin D levels among healthy Caucasian subjects. Hum Genet 2010; 128:549–556.
  • Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, Kiel DP, Streeten EA, Ohlsson C, Koller DL, Peltonen L, Cooper JD, O'Reilly PF, Houston DK, Glazer NL, Vandenput L, Peacock M, Shi J, Rivadeneira F, McCarthy MI, Anneli P, de Boer IH, Mangino M, Kato B, Smyth DJ, Booth SL, Jacques PF, Burke GL, Goodarzi M, Cheung CL, Wolf M, Rice K, Goltzman D, Hidiroglou N, Ladouceur M, Wareham NJ, Hocking LJ, Hart D, Arden NK, Cooper C, Malik S, Fraser WD, Hartikainen AL, Zhai G, Macdonald HM, Forouhi NG, Loos RJ, Reid DM, Hakim A, Dennison E, Liu Y, Power C, Stevens HE, Jaana L, Vasan RS, Soranzo N, Bojunga J, Psaty BM, Lorentzon M, Foroud T, Harris TB, Hofman A, Jansson JO, Cauley JA, Uitterlinden AG, Gibson Q, Järvelin MR, Karasik D, Siscovick DS, Econs MJ, Kritchevsky SB, Florez JC, Todd JA, Dupuis J, Hyppönen E, Spector TD. Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 2010;7;376:180–8.
  • Ahn J, Yu K, Stolzenberg-Solomon R, Simon KC, McCullough ML, Gallicchio L, Jacobs EJ, Ascherio A, Helzlsouer K, Jacobs KB, Li Q, Weinstein SJ, Purdue M, Virtamo J, Horst R, Wheeler W, Chanock S, Hunter DJ, Hayes RB, Kraft P, Albanes D. Genome-wide association study of circulating vitamin D levels. Hum Mol Genet 2010;1;19:2739–45.
  • Kurt O, Yilmaz-Aydogan H, Uyar M, Isbir T, Seyhan MF, Can A. Evaluation of ERα and VDR gene polymorphisms in relation to bone mineral density in Turkish postmenopausal women. Mol Biol Rep 2012;(in press).
  • Lee YH, Choi SJ, Ji JD, Song GG. Vitamin D receptor ApaI, TaqI, BsmI, and FokI polymorphisms and psoriasis susceptibility: a meta-analysis. Mol Biol Rep 2012; (in press).
  • Lee YH, Bae SC, Choi SJ, Ji JD, Song GG. Associations between vitamin D receptor polymorphisms and susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis. Mol Biol Rep 2011;38:3643–51.
  • Morley R, Carlin JB, Pasco JA, Wark JD, Ponsonby AL. Maternal 25-hydroxyvitamin D concentration and offspring birth size: effect modification by infant VDR genotype. Eur J Clin Nutr 63:2009;802–4.
  • Swamy GK, Garrett ME, Miranda ML, Ashley-Koch AE. Maternal vitamin D receptor genetic variation contributes to infant birthweight among black mothers. Am J Med Genet A 2011;155A:1264–71.
  • Ramos-Lopez E, Kahles H, Weber S, Kukic A, Penna-Martinez M, Badenhoop K, Louwen F. Gestational diabetes mellitus and vitamin D deficiency: genetic contribution of CYP27B1 and CYP2R1 polymorphisms. Diabetes Obes Metab 2008;10:683–5.
  • Brannon PM. Vitamin D and adverse pregnancy outcomes: beyond bone health and growth. Proc Nutr Soc 2012; 20:1–8.
  • Bhlon TM, Taffany DA, Welsh, Rowling, MJ. Retinoids modulate expression of the endocytic partners megalin, cubulin and disabled-2 and uptake of vitamin D binding protein in human mammary cells. J Nutr 2008;138:1323–28.
  • Reboul E, Goncalves A, Comera C, Bott R, Nowicki M, Landrier JF, Jourdheuil-Rahmani D, Dufour C, Collet X, Borel P. Vitamin D intestinal absorption is not a simple passive diffusion: evidences for involvement of cholesterol transporters. Mol Nutr Food Res 2011;55:691–702.
  • Bodnar LM, Catov JM, Zmuda JM, Cooper ME, Parrott MS, Roberts JM, Marazita ML, Simhan HN. Maternal serum 25-hydroxyvitamin D concentrations are associated with small-for-gestational age births in white women. J Nutr 2010;140:999–1006.
  • Mahon P, Harvey N, Crozier S, Inskip H, Robinson S, Arden N, Swaminathan R, Cooper C, Godfrey K; SWS Study Group. Low maternal vitamin D status and fetal bone development: cohort study. J Bone Miner Res 2010;25:14–9.
  • McGrath JJ, Eyles DW, Pedersen CB, Anderson C, Ko P, Burne TH, Norgaard-Pedersen B, Hougaard DM, Mortensen PB. Neonatal vitamin D status and risk of schizophrenia: a population-based case-control study. Arch Gen Psychiatry 2010;67:889–94.
  • Gale CR, Robinson SM, Harvey NC, Javaid MK, Jiang B, Martyn CN, Godfrey KM, Cooper C; Princess Anne Hospital Study Group. Maternal vitamin D status during pregnancy and child outcomes. Eur J Clin Nutr 2008; 62: 68–77.
  • Amer M, Qayyum R. elation between serum 25-hydroxyvitamin D and C-reactive protein in asymptomatic adults (from the continuous National Health and Nutrition Examination Survey 2001 to 2006). Am J Cardiol 2012;109:226–30.
  • Ensrud KE, Ewing SK, Fredman L, Hochberg MC, Cauley JA, Hillier TA, Cummings SR, Yaffe K, Cawthon PM; Study of Osteoporotic Fractures Research Group. Circulating 25-hydroxyvitamin D levels and frailty status in older women. J Clin Endocrinol Metab 2010;95:5266–5273.
  • Tuohimaa P, Tenkanen L, Ahonen M, Lumme S, Jellum E, Hallmans G, Stattin P, Harvei S, Hakulinen T, Luostarinen T, Dillner J, Lehtinen M, Hakama M. Both high and low levels of blood vitamin D are associated with a higher prostate cancer risk: a longitudinal, nested case-control study in the Nordic countries. Int J Cancer 2004;108:104–8.
  • Vieth R. Enzyme kinetics hypothesis to explain the U-shaped risk curve for prostate cancer vs. 25-hydroxyvitamin D in nordic countries. Int J. Cancer 2004;111:468.
  • Jones G. Pharmacokinetics of vitamin D toxicity. Am J Clin Nutr 2008;88(suppl):582S–586S.

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