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Original Article

Studies on Tryptophan Metabolism in Male Subjects Treated with Progestational Agents

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Pages 237-249 | Received 09 Dec 1969, Accepted 19 Feb 1970, Published online: 08 Jul 2009

References

  • Altman K., Greengard O. Correlation of kynurenine excretion with liver tryptophan pyrrolase levels in disease and after hydro cortisone induction. J. clin. Invest. 1966; 45: 1525
  • Braunshtein A. E., Goryochenkova E. V., Paskinaja T. S. Enzymatic formation of alanine from L-kynurenine and L-tryptophan, and the role of vitamin B6 in this process. Biochemistry (Leningr.) 1949; 14: 163
  • Brown R. R. The isolation and determination of hydroxy-kynurenine. J. biol. Chem. 1957; 227: 649
  • Brown R. R., Price J. M. Quantitative studies on metabolism of tryptophan in the urine of dog, cat, rat and man. J. biol. Chem. 1956; 219: 985
  • Brown R. R., Rose D. P., Price J. M., Wolf H. Tryptophan metabolism as affected by anovulatory agents. Ann. N. Y. Acad. Sci. 1969; 166: 44
  • Brown R. R., Thornton M. J., Price J. M. The effect of vitamin supplementation on the urinary excretion of tryptophan metabolites by pregnant women. J. clin. Invest. 1961; 40: 617
  • Edgren R. A., Jones R. C. A biological classification of progestational agents. Fertil. and Steril. 1967; 18: 238
  • Elton R. L., Edgren R. A. Biological actions of 17α-(2-methallyl)-19-nortestosterone, an oral ly active progestational agent. Endocrinology 1958; 63: 464
  • Hansson O. Effect of 4-deoxypyridoxine on the initial excretion rates of 3-hydroxykynurenine and 3-hydroxyanthranilic acid after tryptophan loading. Acta Soc. Med. upsalien. 1968; 73: 19
  • Michael A. F., Drummond K. N., Doeden D., Anderson J. A., Good R. A. Trypto phan metabolism in man. J. clin. Invest. 1964; 43: 1730
  • Price J. M., Brown R. R., Ellis M. E. Quantitative studies on the urinary excretion of tryptophan metabolites by humans ingesting a constant diet. J. Nutr. 1956; 60: 323
  • Price J. M., Brown R. R., Larson F. C. Quantitative studies on human urinary meta bolites of tryptophan as affected by isoniazid and deoxypyridoxine. J. clin. Invest. 1957; 36: 1600
  • Price J. M., Brown R. R., Yess N. Testing the functional capacity of the tryptophan -niacin pathway in man by analysis of urinary metabolites. Advanc. Metab. Dis. 1965; 2: 159
  • Reddy S. K., Reynolds M. S., Price J. M. The determination of 4-pyridoxic acid in human urine. J. biol. Chem. 1958; 233: 691
  • Rose D. P. The influence of oestrogens on tryptophan metabolism in man. Clin. Sci. 1966; 31: 265
  • Rose D. P., Brown R. R., Price J. M. The metabolism of tryptophan to nicotinic acid derivatives by women taking oestrogen-proges togen preparations. Nature 1968; 219: 1259
  • Rose D. P., McGinty F. The influence of adrenocortical hormones and vitamins upon tryptophan metabolism in man. Clin. Sci. 1968; 35: 1
  • Satoh K., Price J. M. Fluorometric deter mination of kynurenic acid and xanthurenic acid in human urine. J. biol. Chem. 1958; 230: 781
  • Sprince H., Lowy R. S., Folsome C. E., Behrman J. S. Studies on the urinary excretion of ‘xanthurenic acid’ during normal and ab normal pregnancy: A survey of the excretion of ‘xanthurenic acid’ in normal non-pregnant, normal pregnant, pre-eclamptic and eclamptic women. Amer. J. Obstet. Gynec. 1951; 62: 84
  • Vandelli I. The use of vitamin B6 (pyridoxine) for suppressing the elimination of xanthurenic acid in pregnant and non-pregnant women following the oral intake of measured quantity of tryptophan. Acta vitamin. (Milano) 1951; 5: 55
  • Vivian V. M., Reynolds M. S., Price J. M. Use of ion-exchange resins for the determina tion of N1-methylnicotinamide in human urine. Analyt. Biochem. 1965; 10: 274
  • Wachstein M., Gudaitis A. Disturbance of vitamin B6 metabolism in pregnancy. II. The influence of various amounts of pyridoxine hydrochloride upon the abnormal tryptophan load test in pregnant women. J. Lab. clin. Med. 1953; 42: 98
  • Walters C. J., Brown R. R., Kaihara M., Price J. M. The excretion of N-methyl-2-pyri-done-5-carboxamide by man following ingestion of several known or potential precursors. J. biol. Chem. 1955; 217: 489
  • Weber F., Wiss O. Über die unterschiedliche Beeinflussung des Tryptophan-Stoffwechsels durch Vitamin-B6-Mangel in der Ratte. Z. Physiol. Chem 1963; 331: 124
  • Wertz A. W., Lojkin M. E., Bouchard B. S., Derby M. B. Tryptophan—niacin relation ships in pregnancy. J. Nutr. 1958; 64: 339
  • Wolf H., Brown R. R., Price J. M., Madsen P. O. The effect of hydrocortisone on trypto phan metabolism in human male subjects, In preparation
  • Wolf H., Brown R. R., Price J. M., Mad sen P. O. The effect of hormones on the bio synthesis of nicotinic acid from tryptophan in man. J. clin. Endocr. Metab. 1970; 30: 38
  • Wolf H., Madsen P. O., Price J. M. Studies on the metabolism of tryptophan in patients with benign prostatic hypertrophy or cancer of the prostate. J. Urol. 1968; 100: 537
  • Wolf H., Price J. M., Brown R. R., Madsen P. O. The effect of estrogens on pyridoxal phosphate dependent enzymes in patients with cancer of the prostate. J. Urol, in print
  • Wolf H., Thornton M. J. Unpublished ob servations
  • Yess N., Price J. M., Brown R. R., Swan P. B., Linkswiler H. Vitamin B6 depletion in man: urinary excretion of tryptophan meta bolites. J. Nutr. 1964; 84: 229

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