Advanced search
Publication Cover
Scandinavian Journal of Clinical and Laboratory Investigation Volume 30, 1972 - Issue 2
Submit an article Journal homepage
6
Views
36
CrossRef citations to date
0
Altmetric
Original Article

Intracellular pH of the Brain in Arterial Hypoxemia, Evaluated with the CO2Method and from the Creatine Phosphokinase Equilibrium

V. Macmillan Brain Research Laboratory, E-Blocket, University Hospital, Lund, Sweden
&
B. K. Siesjö Brain Research Laboratory, E-Blocket, University Hospital, Lund, Sweden
Pages 117-125 | Received 28 Mar 1972, Accepted 14 Jul 1972, Published online: 08 Jul 2009

References

  • Danforth W. H. Activation of glycolytic pathway in muscle. Control of Energy Metabolism, B. Chance, R. W. Estabrook, J. R. Williamson. Academic Press, New York 1968; 287–297
  • Eklöf B., MacMillan V., Siesjö B. K. The effect of hypercapnic acidosis upon the energy metabolism of the brain in arterial hypotension caused by bleeding. Acta physiol. scand. 1972, Submitted for publication
  • Krebs H. A., Veech R. L. Regulation of the redox-state of the pyridine nucleotides in rat liver. Pyridine Nucleotide-dependent Dehydrogenases, H. Sund. Springer Verlag, New York 1970; 413–438
  • Kuby S. A., Noltmann E. A. ATP-creatine transphosphorylase. The Enzymes, P. D. Boyer, H. Lardy, K. Myrbäck. Academic Press, New York 1962; Vol. 6: 515–596
  • Lowry O. H., Passonneau J. V. Kinetic evidence for multiple binding sites on phosphofructokinase. J. biol. Chem. 1966; 241: 2268
  • MacMillan V., Siesjö B. K. The effect of arterial hypoxemia upon acid-base parameters in arterial blood and cisternal cerebrospinal fluid of the rat. Acta physiol. scand. 1971; 83: 454
  • MacMillan V., Siesjö B. K. Brain energy metabolism in hypoxemia. Scand. J. clin. Lab. Invest. 1972; 30: 127
  • Mitchell R. A., Herbert D. A., Carman C. T. Acid-base constants and temperature coefficients for cerebrospinal fluid. J. appl. Physiol. 1965; 20: 27
  • Noda L., Kuby S. A., Lardy H. A. Adenosinetriphosphate-creatine transphosphorylase. J. biol. Chem. 1954; 210: 83
  • Pontén U., Siesjö B. K. A method for the determination of the total carbon dioxide content of frozen tissues. Acta physiol. scand. 1964; 60: 297
  • Pontén U., Siesjö B. K. Gradients of CO2tension in the brain. Acta physiol. scand. 1966; 67: 129
  • Rall D. P., Fenstermacher J. D. Volume of cerebral extracellular fluids. Ion Homeostasis of the Brain, B. K. Siesjö, S. C. Sörensen. Munksgaard, Copenhagen 1971; 29–33
  • Rose I. A. The state of magnesium in cells as estimated from the adenylate kinase equilibrium. Proc. nat. Acad. Sci. (Wash.) 1968; 80: 235
  • Severinghaus J. W. Blood gas concentration. Handbook of Physiology. Section 3. Respiration, W. O. Fenn, H. Rahn. American Physiology Society, Washington, D. C. 1965; 1475–1487
  • Siesjö B. K. The solubility of carbon dioxide in cerebral cortical tissue of cats, with a note on the solubility of carbon dioxide in water, 0.16 M NaCl and cerebrospinal fluid. Acta physiol. scand. 1962; 55: 325
  • Siesjö B. K., Nilsson L. The influence of arterial hypoxemia upon labile phosphates and upon extracellular and intracellular lactate and pyruvate concentration in the rat brain. Scand. J. clin. Lab. Invest. 1971; 27: 83
  • Siesjö B. K., Messeter K. Factors determining intracellular pH. Ion Homeostasis of the Brain, B. K. Siesjö, S. C. Sörensen. Munksgaard, Copenhagen 1971; 244–262
  • Siesjö B. K., Folbergrová J., MacMillan V. The effect of hypercapnia upon intracellular pH in the brain evaluated with the bicarbonate-carbonic acid method and from the creatine phosphokinase equilibrium. J. Neurochem. 1972, In press
  • Siggaard-Andersen O. Blood acid-base alignment nomogram. Scand. J. clin. Lab. Invest. 1963; 15: 211
  • Woodward D. L., Reed D. J., Woodbury D. M. Extracellular space of rat cerebral cortex. Amer. J. Physiol. 1967; 212: 367

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.