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Original Article

Effect of Verapamil on pancreatic glucagon release from the isolated, perfused canine pancreas

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Pages 139-142 | Received 22 Sep 1976, Accepted 09 Dec 1976, Published online: 08 Jul 2009

References

  • Devis G., Somers G., Van Obberghen E., Malaisse W. J. Calcium antagonists and islet function. I. Inhibition of insulin release by Verapamil. Diabetes 1975; 24: 547
  • Fleckenstein A. Specific inhibitors and promoters of calcium action in the excitation-contraction coupling of heart muscle and their role in prevention or production of myocardial lesions. Calcium and the Heart, P. Harris, L. Opie. Academic Press, London 1971; 135
  • Fleckenstein A., Grun G., Tritthart H., Byon K. Uterus-relaxation durch hochaktive Ca++ antagonistische Hemmstoffe der elektro-mechanischen Koppelung wie Isoptin (Verapamil, Iproveratril), Substanz D600 und Segontin (Prenylamin). Klin. Wschr. 1971; 49: 32
  • Grodsky G. M., Bennett L. L. Cation requirements for insulin secretion in the isolated, perfused pancreas. Diabetes 1966; 15: 910
  • Hermansen K., Iversen J. Calcium, glucose and glucagon release. Diabetologia 1976; 12: 398
  • Ivcrsen J. Secretion of glucagon from the isolated, perfused canine pancreas. J. clin. Invest. 1971; 50: 2123
  • Iversen J. Adrenergic receptors and the secretion of glucagon and insulin from the isolated, perfused canine pancreas. J. clin. Invest. 1973; 52: 2102
  • Malaisse W. J., Devis G., Pipeleers D. G., Somers G. Calcium antagonists and islet function. IV. Effect of D600. Diabetologia 1976; 12: 77
  • Malaisse W. J., Herchuelz A., Levy J., Somers G., Devis G., Ravazzola M., Malaisse-Lagae F., Orci L. Insulin release and the movements of calcium in the pancreatic islets. Calcium transport in contraction and secretion, E. Carafoli, F. Clementi, W. Drabikowski, A. Margreth. North-Holland Publishing Company Amsterdam-Oxford. American Elsevier Publishing Company, Inc., New York 1975; 211
  • Milner R. D. G., Hales C. N. The role of calcium and magnesium in insulin secretion from rabbit pancreas studied in vitro. Diabetologia 1967; 3: 47
  • ørskov H., Thomsen H. G., Yde H. Wick chromatography for rapid and reliable immunoassay of insulin, glucagon and growth hormone. Nature 1968; 219: 193

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