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Original Article

References

Pages 64-72 | Published online: 08 Jul 2009

References

  • Al-Adnani M. S., McGee J. O'D. C1q production and secretion by fibroblasts. Nature 1976; 263: 145–146
  • Atkins E. D. T., Phelps C. F., Sheehan J. K. The conformation of the mucopolysaccharides. Hyaluronates. Biochem. J. 1972; 128: 1255–1263
  • Atkins E. D. T., Sheehan J. K. Hyaluronates: relation between molecular conformations. Science 1973; 179: 562–564
  • Bacon P. A., Cracchiolo A., Bluestone R., Goldberg L. S. Cell mediated immunity to synovial antigens in RA. Ann. rheum. Dis. 1975; 34: 196–197
  • Balazs E. A., Gibbs D. A. The rheological properties and biological function of hyaluronic acid. Chemistry and Molecular Biology of the Intercellular Matrix, E. A. Balazs. Acad. Press, London and New York 1970; Vol. 3: 1241–1253
  • Balazs E. A., Watson D., Duff I. F., Roseman S. Hyaluronic acid in synovial fluid. Arthritis Rheum. 1967; 10: 357–376
  • Barker S. A., Young N. M. Isolation of hyaluronic acid by gel filtration on agarose. Carbohydrate Res. 1966; 2: 363–370
  • Barland P., Novikoff A. B., Hamerman D. The structure and cytochemistry of the rheumatoid synovial membrane with special reference to lysosomes. Amer. J. Path. 1964; 44: 853–866
  • Barland P., Smith C., Hamerman D. Localization of hyaluronic acid in synovial cells by radioautography. J. Cell Biol. 1968; 37: 13–26
  • Bartfeld H. Rheumatoid arthritic and non-rheumatoid synovium in cell culture: morphological observations, acridine orange and fluorescent fraction II studies. Ann. rheum. Dis. 1965; 24: 31–39
  • Bingham R. W., Burke D. C. Isolation of plasma membrane and endoplasmic reticulum fragments from chick embryo fibroblasts. Biochim. Biophys. Acta 1972; 274: 348–352
  • Subcellular Components2nd ed., G. D. Birnie. Butterworths, London 1972; 320
  • Blau S., Janis R., Hamerman D., Sandson J. Cellular origin of hyaluronate-protein in the human synovial membrane. Science 1965; 150: 353–355
  • Bonner W. M., Laskey R. A. A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. Eur. J. Biochem. 1974; 46: 83–88
  • Bornstein P. The biosynthesis of collagen. Ann. Rev. Biochem. 1974; 43: 567–603
  • Castor C. W. Production of mucopolysaccharides by synovial cells in a simplified tissue culture medium. Proc. Soc. exp. Biol. Med. 1957; 94: 51–56
  • Castor C. W. Regulation of collagen and hyaluronate formation in human synovial fibroblast cultures. J. Lab. Clin. Med. 1970; 75: 798–810
  • Castor C. W. Abnormalities of connective tissue cells cultured from patients with rheumatoid arthritis. II. Defective regulation of hyaluronate and collagen formation. J. Lab. Clin. Med. 1971a; 77: 63–75
  • Castor C. W. Connective tissue activation I. The nature, specificity, measurement and distribution of connective tissue activating peptide. Arthritis Rheum. 1971b; 14: 41–54
  • Castor C. W. Connective tissue activation II. Abnormalities of cultured rheumatoid synovial cells. Arthritis Rheum. 1971c; 14: 55–66
  • Castor C. W. Connective tissue activation III. Observations of the mechanism of action of connective tissue activating peptide. J. Lab. Clin. Med. 1972; 79: 285–301
  • Castor C. W. Synovial cell activation induced by a polypeptide mediator. Ann. N. Y. Acad. Sci. 1975; 256: 304–317
  • Castor C. W., Dorstewitz E. L. Abnormalities of connective tissue cells from patients with rheumatoid arthritis. I. Relative unresponsiveness of rheumatoid synovial cells to hydrocortisone. J. Lab. Clin. Med. 1966; 68: 300–313
  • Castor C. W., Fries F. F. Composition and function of human synovial connective tissue cells measured in vitro. J. Lab. Clin. Med. 1961; 57: 394–407
  • Castor C. W., Lewis R. B. Connective tissue activation X. Current studies of the process and its mediators. Scand. J. Rheumatol. 1976; 5(Suppl. 12)41–54
  • Castor C. W., Muirden K. D. Collagen formation in monolayer cultures of human fibroblasts. The effects of hydrocortisone. Lab. Invest. 1964; 13: 560–574
  • Castor C. W., Rowe K. Collagen formation by rheumatoid and non-rheumatoid cell strains: regulation by ascorbic acid and hydrocortisone. Arthritis Rheum. 1968; 11: 819
  • Chayen J., Bitensky L. Lysosomal enzymes and inflammation with particular reference to rheumatoid diseases. Ann. rheum. Dis. 1971; 30: 522–536
  • Clarris B. J., Fraser R. E. Barrier around synovial cells in vitro. Nature 1967; 214: 1159
  • Cracchiolo A., Michaeli D., Goldberg L. S., Fudenberg H. H. The occurrence of antibodies to collagen in synovial fluids. Clin. Immunol. Immunopathol. 1975; 3: 567–574
  • Davidson J. M., McEmeany L. S. G., Bornstein P. Intermediates in the limited proteolytic conversion of procollagen to collagen. Biochemistry 1975; 14: 5188–5194
  • Dea I. C. M., Moorhouse R., Rees D. A., Arnott S., Guss J. M., Balazs E. A. Hyaluronic acid: a novel, double helical molecule. Science 1973; 179: 560–562
  • de Duve C. The role of lysosomes in the pathogeny of disease. Scand. J. Rheumatol. 1976; 5(Suppl. 12)63–66
  • Earl D. C. N., Korner A. The isolation and properties of cardiac ribosomes and polysomes. Biochem J. 1965; 94: 721–734
  • Egelius N., Jonsson E., Sundblad L. Studies of hyaluronic acid in rheumatoid arthritis. Ann. rheum. Dis. 1956; 15: 357–363
  • Epstein E. H., Jr. [α1 (III)]3human skin collagen. Release by pepsin digestion and preponderance in fetal life. J. Biol. Chem. 1974; 249: 3225–3231
  • Epstein E. H., Jr., Munderloh N. H. Isolation and characterization of CNBr peptides of human [α1 (III)]3 collagen and tissue distribution of [α1 (I)]2 α2 and [α1 (III)]3 collagens. J. Biol. Chem. 1975; 250: 9304–9312
  • Evanson J. M. Collagen degradation by explanted synovial tissue. Chemistry and Molecular Biology of the Intercellular Matrix, E. A. Balazs. Acad. Press, London and New York 1970; Vol. 3: 1637–1652
  • Evanson J. M., Jeffrey J. J., Krane S. M. A collagenolytic enzyme from rheumatoid synovium in tissue culture. Clin. Res. 1967; 15: 293
  • Eyre D. R., Muir H. Type-III collagen in synovium. Lancet 1975a; i: 609–610
  • Eyre D. R., Muir H. Type III collagen: a major constituent of rheumatoid and normal human synovial membrane. Conn. Tis. Res. 1975b; 4: 11–16
  • Farr M., Kendall M. J., Shuttleworth R., Meynell M. J., Hawkins C. F. Source and significance of 5′-nucleotidase in synovial fluid. Ann. rheum. Dis. 1973; 32: 326–330
  • Ferguson J., Boyle J. A., Nuki G. Rheological evidence for the existence of dissociated macromolecular complexes in rheumatoid synovial fluid. Clin. Sci. 1969; 37: 739–750
  • Fessler L. I., Morris N. P., Fessler J. H. Procollagen: biological scission of amino and carboxy extension peptides. Proc. Nat. Acad. Sci. USA 1975; 72: 4905–4909
  • Fraser J. R. E., Catt K. J. Human synovial-cell culture. Use of a new method in a study of rheumatoid arthritis. Lancet 1961; ii: 1437–1439
  • Gahmberg C. G., Simons K. Isolation of plasma membrane fragments from BHK 21 cells. Acta Pathol. Microbiol. Scand. B 1970; 78: 176–182
  • Gardner D. L. The Pathology of Rheumatoid Arthritis. Edward Arnold, London 1972
  • Ghadially F. N., Roy S. Ultrastructure of synovial membrane in rheumatoid arthritis. Ann. rheum. Dis. 1967; 26: 426–443
  • Ghadially F. N., Roy S. Ultrastructure of Synovial Joints in Health and Disease. Butterwirths, London 1969
  • Ghose T., Woodbury J. F., Hansell N. M. Interaction in vitro between synovial cells and autologous lymphocytes and sera from arthritis patients. J. Clin. Pathol. 1975; 28: 550–558
  • Gianetto R., de Duve G. Tissue fractionation studies. 4. Comparative study of the binding of acid phosphatase, β-glucuronidase and cathepsin by rat-liver particles. Biochem. J. 1955; 59: 433–438
  • Goldbarg J. A., Rutenburg A. M. The colorimetric determination of leucine aminopeptidase in urine and serum of normal subjects and patients with cancer and other diseases. Cancer 1958; 11: 283–291
  • Goldfisher S., Smith C., Hamerman D. Altered acid hydrolase activities in rheumatoid synovial cells in culture. Amer. J. Path. 1968; 52: 569–578
  • Graham J. M. Isolation and characterization of membranes from normal and transformed tissue-culture cells. Biochem. J. 1972; 130: 1113–1124
  • Granda J. L., Ranawat C. S., Posner A. S. Levels of three hydrolases in rheumatoid and regenerated synovium. Arthritis Rheum. 1971; 14: 223–230
  • Grant M. E., Prockop D. J. The biosynthesis of collagen. N. Eng. J. Med., 286: 194–199; 242–249; 291–300
  • Griffiths M. M., Ward J. R., Smith C. B. Cytotoxicity of rheumatoid lymphocytes for synovial cells. Arthritis Rheum. 1975; 18: 403–404
  • Grossfeld H., Meyer K., Godman G. Differentiation of fibroblasts in tissue culture, as determined by mucopolysaccharide production. Proc. Soc. exp. Biol. Med. 1955; 88: 31–35
  • Hamerman D. Evidence for an infectious etiology of rheumatoid arthritis. Ann. N. Y. Acad. Sci. 1975; 256: 25–38
  • Hamerman D., Barland P., Janis R. The structure and chemistry of the synovial membrane in health and disease. The Biological Bases of Medicine, E. E. Bittar, N. Bittar. Acad. Press, London and New York 1969; 269–309
  • Hedberg H., Moritz U. Biosynthesis of hyaluronic acid in tissue cultures of human synovial membrane. Proc. Soc. exp. Biol. Med. 1958; 98: 80–84
  • Hedberg H., Moritz U. Intrinsic viscosity of hyaluronic acid synthetized in tissue culture in the presence of normal and rheumatoid arthritic serum respectively. Acta rheum. Scand. 1959; 5: 169–178
  • Hendry N. G., Carr A. L. A glycosidase abnormality in synovial membrane in joint disease. Nature 1963; 199: 392
  • Hinton R. H., Dobrota M., Fitzsimons J. T. R., Reid E. Preparation of a plasma membrane fraction from rat liver by zonal centrifugation. Eur. J. Biochem. 1970; 12: 349–359
  • Arthritis and Allied Conditions, J. L. Hollander. Lea & Febiger, Philadelphia 1972
  • Hopwood J. J., Robinson H. C. The molecular-weight distribution of glycosaminoglycans. Biochem. J. 1973; 135: 631–637
  • How M. J., Lang V. J. W., Stanworth D. R. The association of hyaluronic acid with protein in human synovial fluid. Biochim. Biophys. Acta 1969; 194: 81–90
  • Hunter M. J., Commerford S. L. Pressure homogenization of mammalian tissues. Biochim. Biophys. Acta 1961; 47: 580–586
  • Ishimoto N., Temin H. M., Strominger J. L. Studies on carcinogenesis by avian sarcoma viruses. II Virus-induced increase in hyaluronic acid synthetase in chicken fibroblasts. J. Biol. Chem. 1966; 241: 2052–2057
  • Israel A., Verjus M.-A., Semmel M. Isolation and characterization of surface membranes from chorioallantoin cells and chick fibroblasts. Biochim. Biophys. Acta 1973; 318: 155–166
  • Jacobson B. The biosynthesis of hyaluronic acid. Chemistry and Molecular Biology of the Intercellular Matrix, E. A. Balazs. Acad. Press, London and New York 1970; Vol. 2: 763–781
  • Janis R., Sandson J., Smith C., Hamerman D. Synovial cell synthesis of a substance immunologically like cartilage proteinpolysaccharide. Science 1967; 158: 1464–1467
  • Jeanloz R. W. Mucopolysaccharides (Acid glycosaminoglycans). Comprehensive Biochemistry, M. Florkin, E. H. Stotz. Elsevier, Amsterdam 1963; Vol. 5: 262–296
  • Jessar R. A. The study of synovial fluid. Arthritis and Allied Conditions, J. L. Hollander. Lea & Febiger, Philadelphia 1972; 67–81
  • Kar N. C., Cracchiolo A., Mirra J., Pearson C. M. Acid, neutral and alkaline hydrolases in arthritis synovium. Amer. J. clin. Path. 1976; 65: 220–228
  • Keski-Oja J., Mosher D. F., Vaheri A. Dimeric character of fibronectin, a major cell surface-associated glycoprotein. Biochem. Biophys. Res. Comm. 1977, in press
  • Kinsella T. D., Baum J., Ziff M. Studies of isolated synovial lining cells of rheumatoid and nonrheumatoid synovial membranes. Arthritis Rheum. 1970; 13: 734–753
  • Kivirikko K. I. Urinary excretion of hydroxyproline in health and disease. International Review of Connective Tissue Research, D. A. Hall, D. S. Jackson. Acad. Press, London and New York 1970; Vol. 5: 93–163
  • Kivirikko K. I., Risteli L. Biosynthesis of collagen and its alterations in pathological states. Medic. Biol. 1976; 54: 159–186
  • Kling D. H., Levine M. G., Wise S. Mucopolysaccharides in tissue cultures of huan and mammalian synovial membrane. Proc. Soc. exp. Biol. Med. 1955; 89: 261–263
  • Kornfeld S., Ginsburg V. The metabolism of glucosamine by tissue culture cells. Exp. Cell Res. 1966; 41: 592–600
  • Krane S. M. Collagenase production by human synovial tissues. Ann. N. Y. Acad. Sci. 1975a; 256: 289–303
  • Krane S. M. Degradation of collagen in connective tissue diseases. Rheumatoid arthritis. Dynamics of Connective Tissue Macromolecules, P. M. C. Burleigh, A. R. Poole. North Holland, Amsterdam and Oxford 1975b; 309–24
  • Kühn K., Fietzek P. P. The structure of collagen. Collagen Metabolism in the Liver, H. Popper, K. Becker. Stratton, New York 1975; 15–28
  • Kulonen E. Studies on hyaluronic acid and hyaluronidase in the animal organism. Acta physiol. Scand. 1951; 24(Suppl. 88)100
  • Kulonen E. Studies on experimental granuloma. Chemistry and Molecular Biology of the Intercellular Matrix, E. A. Balazs. Acad. Press, London and New York 1970; 1811–1820
  • Kulonen E. Reactivity of the connective tissue. Biology of Fibroblast, E. Kulonen, J. Fikkarainen. Acad. Press, London and New York 1973; 3–7
  • Kulonen E., Mäkisara P., Seppälä P., Näntö V. Physicochemical properties of synovial fluid with reference to rheumatoid disease and the effect of hydrocortisone treatment. Feder. Proc. 1966; 25: 1141–1143
  • Biology of Fibroblast, E. Kulonen, J. Pikkarainen. Acad. Press, London and New York 1973
  • Kulonen E., Seppälä P., Näntö V. Synovial fluid in rheumatoid arthritis and the action of glucocorticoids. Rheumatoid Arthritis, W. Müller, H.-G. Harwerth, K. Fehr. Acad. Press, London and New York 1971; 585–588
  • Lack C. H. Lysosomes in relation to arthritis. Lysosomes in Biology and Pathology I, J. T. Dingle, H. B. Fell. North-Holland, Amsterdam 1969; 493–508
  • Laskey R. A., Mills A. D. Quantitative film detection of 3H and 14C in polyacryl- amide gels by fluorography. Eur. J. Biochem. 1975; 56: 335–341
  • Lauf P. K. Antigen-antibody reactions and cation transport in biomembranes: immuno- physiological aspects. Biochim. Biophys. Acta 1975; 435: 173–229
  • Laurent T. C. Structure of hyaluronic acid. Chemistry and Molecular Biology of the Intercellular Matrix, E. A. Balazs. Acad. Press, London and New York 1970; Vol. 2: 703–732
  • Layman D. L., McGoodwin E. B., Martin G. R. The nature of the collagen synthetized by cultured human fibroblasts. Proc. Nat. Acad. Sci. USA 1971; 68: 454–458
  • Lehtinen P., Känkänen L., Kulonen E. Properties of plasma membranes from granulation tissue with reference to extracellular matrix. Acta chem. Scaud. 1975a; 29: 963–968
  • Lehtinen P., Vuorio E., Kulonen E. Plasma membranes from experimental granulation tissue. Biochem. J. 1975b; 146: 565–573
  • Lelievre L. Plasma membranes from fibroblastic cells in culture. Isolation, morphological and enzymatic identification. Biochim. Biophys. Acta 1973; 291: 662–670
  • Lichtenstein J. R., Byers P. H., Smith B. D., Martin G. R. Identification of the collagenous proteins synthetized by cultured cells from human skin. Biochemistry 1975; 14: 1589–1594
  • Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951; 193: 265–275
  • Luscombe M. Acid phosphatase and catheptic activity in rheumatoid synovial tissue. Nature 1963; 197: 1010
  • Mäkinen (Mäkisara) P. Synovial fluid in rheumatoid arthritis. Ann. Med. exp. biol. Fenn. 1958; 36(Suppl. 7)70
  • Marsh J. M., Spencer S., Wiebkin O., Maini R. N., Dumonde D. C., Muir H. Heterogeneity of human synovial tissue cultures. Ann. rheum. Dis. 1974; 33: 578
  • Martin G. R., Byers P. H., Piez K. A. Procollagen. Adv. Enzymol. 1975; 42: 167–191
  • Martin J. B., Doty D. M. Determination of inorganic phosphate. Anal. Chem. 1949; 21: 965–967
  • Matalon R., Dorfman A. The structure of acid mucopolysaccharides produced by Hurler fibroblasts in tissue culture. Proc. Nat. Acad. Sci. USA. 1968; 60: 179–185
  • Meyer K. Hyaluronidases. The Enzymes3rd edition, P. D. Boyer. Acad. Press, London and New York 1971; Vol. V: 307–320
  • Michaeli D., Fudenberg H. H. The incidence and antigenic specificity of antibodies against denatured human collagen in rheumatoid arthritis. Clin. Immunol. Immunopathol. 1974; 2: 153–159
  • Michell R. H., Hawthorne J. N. The site of diphosphoinositide synthesis in rat liver. Biochem. Biophys. Res. Comm. 1965; 21: 333–338
  • Miller E. J., Epstein E. H., Jr, Piez K. A. Identification of three genetically distinct collagens by cyanogen bromide cleavage of insoluble human skin and cartilage collagen. Biochem. Biophys. Res. Comm. 1971; 42: 1024–1029
  • Miller E. J., Matukas V. J. Biosynthesis of collagen, the biochemist's view. Fed. Proc. 1974; 33: 1197–1204
  • Mohr W., Beneke G. Synovial cell cultures for the study of the pathogenesis of rheumatoid arthritis. Beitr. Pathol. 1974; 153: 225–243
  • Monson J. M., Bornstein P. Identification of a disulfide-linked procollagen as the biosynthetic precursor of chick-bone collagen. Proc. Nat. Acad. Sci. USA. 1973; 70: 3521–3525
  • Muirden K. D. Lysosomal enzymes in synovial membrane in rheumatoid arthritis. Relationship to joint damage. Ann. rheum. Dis. 1972; 31: 265–271
  • Munthe E., Natvig J. B. Complement-fixing intracellular complexes of IgG rheumatoid factor in rheumatoid plasma cells. Scand. J. Rheumatol. 1972; 1: 217–229
  • Näntö V. Electrophoretic analysis of acidic glycosaminoglycans and its application to the developing chick embryo. Ann. Acad. Sci. Fenn. A. 1969; 144: 72
  • Nelson-Rees W. A., Flandermeyer R. R. HeLa cultures defined. Science 1976; 191: 96–98
  • Norton W. L., Ziff M. Electron microscopic observations on the rheumatoid synovial membrane. Arthritis Rheum. 1966; 9: 589–610
  • Ogston A. G. The biological functions of the glycosaminoglycans. Chemistry and Molecular Biology of the Intercellular Matrix, E. A. Balazs. Acad. Press, London and New York 1970; Vol. 3: 1231–1240
  • Palmer D. G. Dispersed cell cultures of rheumatoid synovial membrane. Acta rheum. Scand. 1970; 16: 261–270
  • Pardee A. B. The cell surface and fibroblast proliferation. Some current research trends. Biochim. Biophys. Acta 1975; 417: 153–172
  • Partridge S. M. Elastin biosynthesis and the influence of some extracellular factors of macromolecular organization. Biology of Fibroblast, E. Kulonen, J. Pikkarainen. Acad. Press, London and New York 1973; 13–39
  • Penttinen R. P., Lichtenstein J. R., Martin G. R., McKusick V. A. Abnormal collagen metabolism in cultured cells in osteogenesis imperfecta. Proc. Nat. Acad. Sci. USA. 1975; 72: 586–589
  • Perdue J. F., Sneider J. The isolation and characterization of the plasma membrane from chick embryo fibroblasts. Biochim. Biophys. Acta 1970; 196: 125–140
  • Perez-Tamayo R. Collagen dagradation and resorption: physiology and pathology. Molecular Pathology of Connective Tissue, R. Pérez-Tamayo, M. Rojkind. Marcel Dekker, New York 1973; 229–322
  • Perper R. J. Mechanisms of tissue injury with reference to rheumatoid arthritis. Ann. N. Y. Acad. Sci. 1975; 256: 450
  • Peterkofsky B., Diegelman. Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins. Biochemistry 1971; 10: 988–994
  • Piez K. A. Primary structure. Biochemistry of Collagen, G. N. Ramachandran, A. H. Reddi. Plenum Press, New York 1976; 1–44
  • Piez K. A., Eigner E. A., Lewis M. S. The chromatographic separation and amino acid composition of the subunits of several collagens. Biochemistry 1963; 2: 58–66
  • Pope F. M., Martin G. R., Lichtenstein J. R., Penttinen R., Gerson B., Rowe D. W., McKusick V. A. Patients with Ehlers-Danlos syndrome type IV lack type III collagen. Proc. Nat. Acad. Sci. USA. 1975; 72: 1314–1316
  • Remachandran G. N., Ramakrishnan C. Molecular structure. Biochemistry of Collagen, G. N. Ramachandran, A. H. Reddi. Plenum Press, New York 1976; 45–84
  • Reid K. B. M. A collagen-like amino acid sequence in a polypeptide chain of human C1q (a subcomponent of the first component of complement). Biochem. J. 1974; 141: 189–203
  • Reid K. B. M., Porter R. R. Subunit composition and structure of subcomponent C1q of the first component of human complement. Biochem. J. 1976; 155: 19–23
  • Remberger K., Gay S., Adelmann B. C., Timpl R. Immunohistochemical demonstration of different collagen-types in synovial membranes and synovial fluids of rheumatoid arthritis. Scand. J. Rheumatol. 1975; 4(Suppl. 8), Abstract 36–02
  • Roberts J. E., McLees B. D., Kerby G. P. Pathways of glucose metabolism in rheumatoid and nonrheumatoid synovial membrane. J. Lab. clin. Med. 1967; 70: 503–511
  • Primer on the rheumatic diseases. JAMA 1973; 224: 661–812, Rodnan, G. P. (ed.)
  • Rogers H. J. The structure and function of hyaluronate. Biochem. Soc. Symp. (Cambridge) 1961; 20: 51–59
  • Ropes M. W., Bennett G. A., Bauer W. The origin and nature of normal synovial fluid. J. clin. Invest. 1939; 18: 351–372
  • Ruoslahti E., Vaheri A. Novel human serum protein from fibroblast plasma membrane. Nature 1974; 248: 789–791
  • Scher I., Barland P. Studies of surface membranes of two mouse fibroblast cell lines. Biochim. Biphys. Acta 1972; 255: 580–588
  • Scher I., Hamerman P. Isolation of human synovial fluid hyaluronate by density-gradient ultracentrifugation and evaluation of its protein content. Biochem. J. 1972; 126: 1073–1080
  • Scott J. E. Composition and structure of the pericellular environment. Phil. Trans. R. Soc. Lond. B. 1975; 271: 235–242
  • Seppälä P. Synovial fluid in rheumatoid arthritis. Scand. J. Clin. Lab. Invest. 1964; 16(Suppl. 79)107
  • Seppälä P., Lehtonen A., Kärkkäinen J., Näntö V. The presence of chondroitin sulfate in the synovial fluid in rheumatoid arthritis. Clin. Chim. Acta 1967; 16: 115–119
  • Silbert J. E. Biosynthesis of mucopolysaccharides and protein-polysaccharides. Molecular Pathology of Connective Tissues, R. Perez-Tamayo, M. Rojkind. Marcel Dekker, New York 1973; 323–353
  • Smith B. D., Byers P. H., Martin G. R. Production of procollagen by human fibroblasts in culture. Proc. Nat. Acad. Sci. USA. 1972; 69: 3260–3266
  • Smith C. A. Properties of synovial cells in culture. J. exp. Med. 1971; 134: 306s–312s
  • Smith C. A., Hamerman D. Partial inhibition by cycloheximide of hyaluronate synthesis in cell culture. Proc. Soc. exp. biol. Med. 1968; 127: 988–991
  • Smith C. A., Hamerman D. Significance of persistent differences between normal and rheumatoid synovial membrane cells in culture. Arthritis Rheum. 1969; 12: 639–645
  • Smith E. J., Crittenden L. B. Proteins and glycoproteins in plasma membrane fractions of avian leucosis-sarcoma virus susceptible and resistent embryo fibroblasts. Biochim. Biophys. Acta 1973; 298: 608–619
  • Stanfield A. B., Stephens C. A. L., Jr. Studies of cells cultured from synovial tissues. Texas Rep. Biol. Med. 1963; 21: 400–411
  • Steck T. L., Wallach D. F. H. The isolation of plasma membranes. Methods in Cancer Research, H. Busch. Acad. Press, London and New York 1970; Vol. V: 93–153
  • Steffen C. Consideration of pathogenesis of rheumatoid arthritis as collagen autoimmunity. Z. Immun.-forsch. 1970; 139: 219–227
  • Stephens R. W., Ghosh P., Taylor T. K. F. The characterization and function of the polysaccharidases of human synovial fluid in rheumatoid and osteoarthritis. Biochim. Biophys. Acta 1975; 399: 101–112
  • Steven F. S. Evidence for the chemical modification of collagen in rheumatoid arthritis. Ann. rheum. Dis. 1965; 24: 473–476
  • Steven F. S. Evidence for a deficiency in inter-molecular cross-linking in collagen fibrils isolated from rheumatoid joints. Ann. rheum. Dis. 1966; 25: 536–566
  • Stoolmiller A. C., Dorfman A. The metabolism of glycosaminoglycans. Comprehensive Biochemistry, M. Florkin, E. H. Stotz. Elsevier, Amsterdam 1969; Vol. XVII: 241–275
  • Sundblad L. Glycosaminoglycans and glycoproteins in synovial fluid. The Amino Sugars, E. A. Balazs, R. W. Jeanloz. Acad. Press, London and New York 1965; Vol. II A: 229–250
  • Swann D. A., Radin E. L., Nazimec M., Weisser P. A., Curran N., Lewinrek G. Role of hyaluronic acid in joint lubrication. Ann. rheum. Dis. 1974; 33: 318–326
  • Swanson P. D., Bradford H. F., McIlwain H. Stimulation and solubilization of the sodium ion-activated adenosine triphosphatase of cerebral microsomes by surface-active agents, especially polyoxyethylene ethers: actions of phospholipases and a neuraminidase. Biochem. J. 1964; 92: 235–247
  • Takala I., Mäkisara P., Kulonen E. The activities of plasma-membrane marker enzymes in rheumatoid synovial tissues and fluids. Scand. J. Rheumatol
  • Thunell S., Antonopoulos C. A., Gardell S. Analysis of aortic glycosaminoglycans from various animal species by CPC-cellulose column procedures. J. Arterioscler. Res. 1967; 7: 283–294
  • Timpl R. Immunological studies on collagen. Biochemistry of Collagen, G. N. Ramachandran, A. H. Reddi. Plenum Press, New York 1976; 319–375
  • Uitto J. Collagen biosynthesis in human skin. A review with emphasis on scleroderma. Ann. Clin. Res. 1971; 3: 250–258
  • Uitto J., Lindy S., Rokkanen P., Vainio K. Increased protocollagen proline hydroxylase activity in synovial tissue in rheumatoid arthritis. Clin. Chim. Acta 1970; 30: 741–744
  • Uitto J., Lindy S., Turto H., Vainio K. Collagen biosynthesis in rheumatoid synovial tissue. J. Lab. din. Med. 1972; 79: 960–971
  • Vainio U. A histochemical study on leucinoaminopeptidase activity in the synovial membrane of patients with rheumatoid arthritis. Ann. rheum. Dis. 1966; 25: 253–258
  • Vainio U. Non-specific esterases in rheumatoid arthritis. Academic dissertation, Helsinki, Painoseppä KY 1976; 78
  • Vaubel E. The form and fuction of synovial cells in tissue culture I. Morphology of the cells under varying conditions. J. exp. Med. 1933a; 58: 63–83
  • Vaubel E. The form and function of synovial cells in tissue culture II. The production of mucin. J. exp. Med. 1933b; 58: 85–95
  • Wager O. Immunopathogenic mechanisms in rheumatoid diseases with special reference to IgM rheumatoid factor. Scand. J. Rheumatol. 1976; 5(Suppl. 12)67–76
  • Wallach D. F. H., Liu P. S. A critical evaluation of plasma membrane fractionation. Biochim. Biophys. Acta 1973; 300: 211–254
  • Wallach D. F. H., Winzler R. J. Evolving Strategies and Tactics in Membrane Research. Springer-Verlag, New York 1974
  • Warren L., Glick M.-C., Nass M. K. Membranes of animal cells. 1. Methods of isolation of the surface membranes. J. Cell Physiol. 1966; 68: 269–287
  • Waxman B. A., Sledge C. G. Correlation of histochemical, histologic and biochemical evaluations of human synovium with clinical activity. Arthritis Rheum. 1973; 16: 376–382
  • Wegelius O., Klockars M., Vainio U. Acid phosphatase activity in rheumatoid synovia. Acta med. Scand. 1968; 183: 549–551
  • Wegelius O., Rasekhy E., Toropainen L. VIII European Rheumatology Congress. Scand. J. Rheumatol. 1976; 5(Suppl. 12)155
  • Weiss J., Leibovich S. J., Hunter J. A., Cawley M. I. Abnormalities in rheumatoid synovial collagen: studies on synovial polymeric collagens (PC) from normal individuals and patients with rheumatoid and other arthropathies. Ann. rheum. Dis. 1974; 33: 404
  • Weiss J., Shuttleworth C. A., Brown R., Hunter J. A. A. Polymeric type-III collagen in inflamed human synovia. Lancet 1975a; i: 85
  • Weiss J., Shuttleworth C. A., Brown R., Sedowfia K., Baildan A., Hunter J. Occurrence of type III collagen in inflamed synovial membranes: a comparison between non-rheumatoid, rheumatoid and normal synovial collagens. Biochem. Biophys. Res. Comm. 1975b; 65: 907–912
  • Weissmann G. Lysosomes and joint disease. Arthritis Rheum. 1966; 9: 834–840
  • Werb Z., Burleigh M. C. A specific collagenase from rabbit fibroblasts in monolayer culture. Biochem. J. 1974; 337: 373–385
  • Wiebkin O. W., Muir H. The inhibition of sulfate incorporation in isolated adult chondrocytes by hyaluronic acid. FEBS Letters 1973; 37: 42–46
  • Williamson N., James K., Ling N. A., Halt L. P. Synovial cells. A study of the morphology and an examination of protein synthesis of synovial cells. Ann. rheum. Dis. 1966; 25: 534–546
  • Wynne-Roberts C. R., Castor C. W. Ultrastructural comparison of rheumatoid and nonrheumatoid synovial fibroblasts grown in tissue culture. Arthritis Rheum. 1972; 15: 65–83
  • Yehia S. R., Duncan H. Synovial fluid analysis. Clin. Orthop. 1975; 107: 11–25
  • Yielding K. L., Tomkins G. M., Bunim J. J. Synthesis of hyaluronic acid in human synovial tissue slices. Science 1957; 125: 1300
  • Zvaifler N. J. Further speculation on the pathogenesis of joint inflammation in rheumatoid arthritis. Arthritis Rheum. 1970; 13: 895–901

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