The relation between carbohydrate extraction by the forearm and arterial free fatty acid concentration in man: I. Forearm work with nicotinic acid infusion

References

• Ahlborg G., Felig P., Hagenfeldt L., Hendler R., Wahren J. Substrate turnover during prolonged exercise in man: Splanchnic and leg metabolism of glucose, free fatty acids and amino acids. J. clin. Invest. 1974; 53: 1080
   PubMed Web of Science ®Google Scholar
• Beatty C. H., Bocek R. M. Interrelation of carbohydrate and palmitate metabolism in skeletal muscle. Amer. J. Physiol. 1971; 220: 1928
   PubMedGoogle Scholar
• BergStröm J., Hermansen L., Hultman E., Saltin B. Diet, muscle glycogen and physical performance. Acta physiol. scand. 1967; 71: 140
   PubMedGoogle Scholar
• BergStröm J., Hultman E., Jorfeldt L., Pernow B., Wahren J. Effect of nicotinic acid on physical working capacity and on metabolism of muscle glycogen in man. J. appl. Physiol. 1967; 26: 170
   Web of Science ®Google Scholar
• Bücher T., Czok R., Lamprecht W., Pyruvat E., Latzko P. Methoden der Enzymatischen Analyse., H. U. Bergmeyer. Verlag Chemie, Wein-heim/Bergstr. 1962; 253
   Google Scholar
• Carlson L. A. Studies on the effect of nicotinic acid on catecholamine stimulated lipolysis in adipose tissue in vitro. Acta med. scand. 1963; 173: 719
   PubMed Web of Science ®Google Scholar
• Carlson L. A., Fröberg S. O., Nye E. R. Acute effects of nicotinic acid on plasma, liver, heart and muscle lipids. II. Nicotinic acid in the rat. Acta med. scand. 1966; 180: 571
   PubMed Web of Science ®Google Scholar
• Cassens R. G., Bocek R. M., Beatty C. H. Effect of octanoate on carbohydrate metabolism in red and white muscle of the rhesus monkey. Amer. J. Physiol. 1969; 217: 715
   PubMedGoogle Scholar
• Christensen E. H., Hansen O. Untersuchungen über die Verbrennungsvorgänge bei langdauernder, schwerer Muskelarbeit. Skand. Arch. Physiol. 1939; 81: 152
   Google Scholar
• Coles D. R., Cooper K. E., Mottram R. F., Occleshaw J. V. The source of blood samples withdrawn from deep forearm veins via catheters passed upstream from the median cubital vein. J. Physiol. 1958; 142: 323
   PubMed Web of Science ®Google Scholar
• Dohn K. Plethysmographs usable during functional states recording volume changes in ml per 100 ml of extremity. Rep. Steno. Hasp. 1956; 6: 147
   Google Scholar
• Dole V. P. A relation between non-esterified fatty acids in plasma and the metabolism of glucose. J. clin. Invest. 1956; 35: 150
   PubMed Web of Science ®Google Scholar
• Essén B., Hagenfeldt L., Kaijser L. Skeletal muscle utilization of intramuscular and bloodborne substrates in continuous and intermittent exercise. J. Physiol. 1977; 265: 489
   PubMed Web of Science ®Google Scholar
• Essên B., Jansson E., Henriksson J., Taylor A. W., Saltin B. Metabolic characteristics of fibre types in human skeletal muscle. Acta physiol. scand. 1975; 95: 153
   PubMedGoogle Scholar
• Garland P. B., Randle P. J. Control of pyruvate dehydrogenase in the perfused rat heart by the intracellular concentration of acetylcoenzyme A. Biochem. J. 1964; 91: 6
   PubMed Web of Science ®Google Scholar
• Goodale W. T., Hackel D. B. Myocardial carbohydrate metabolism in normal dogs with effects of hyperglycemia and starvation. Circulat. Res. 1953; 1: 509
   PubMed Web of Science ®Google Scholar
• Graf K., Westersten A. Untersuchungen über Eigenschaften und Verwendungsmöglichkeiten eines flexiblen Extremitätenplethysmografen. Acta physiol. scand. 1959; 46: 1
   Google Scholar
• Hagenfeldt L., Wahren J. Human forearm muscle metabolism during exercise. II. Uptake, release and oxidation of individual FFA and glycerol. Scand. J. clin. Lab. Invest. 1968; 21: 263
   PubMed Web of Science ®Google Scholar
• Hagenfeldt L., Wahren J. Human forearm muscle metabolism during exercise. VII. FFA uptake and oxidation at different work intensities. Scand. J. clin. Lab. Invest. 1972; 30: 429
   PubMed Web of Science ®Google Scholar
• Hjelm M. Enzymatic determination of hexoses in blood and urine. Scand. J. clin. Lab. Invest. 1966; 18: 85, Suppl. 192
   Web of Science ®Google Scholar
• Ho R. J. Radiochemical assay of longchain fatty acids using 63Ni as tracer. Analyt. Biochem. 1970; 36: 105
   PubMed Web of Science ®Google Scholar
• Holmgren A., Pernow B. Spectrophotometric measurements of oxygen saturation of blood in the determination of cardiac output. A comparison with the van Slyke method. Scand. J. clin. Lab. Invest. 1959; 11: 143
   Web of Science ®Google Scholar
• Jorfeldt L., Wahren J. Human forearm muscle metabolism during exercise. V. Quantitative aspects of glucose uptake and lactate production during prolonged exercise. Scand. J. clin. Lab. Invest. 1970; 26: 73
   PubMed Web of Science ®Google Scholar
• Kaijser L. Limiting factors for aerobic work performance. Acta physiol. scand. 1970; 89, Suppl. 346.
   Google Scholar
• Kaijser L., Lassers B. W., Wahlqvist MX., Carlson L. A. Myocardial lipid and carbohydrate metabolism in fasting men during prolonged exercise. J. appl. Physiol. 1972; 32: 847
   PubMed Web of Science ®Google Scholar
• Lassers B. W., Carlson L. A., Kaijser L., Wahlqvist M. L. The nature and control of myocardial substrate metabolism in healthy man. Effects of acute ischaemia on myocardial function., M. F. Oliver, D.-G. Julian, K. W. Donald. Churchill Livingstone, Edinburgh 1972; 200
   Google Scholar
• Lassers B. W., Kaijser L., Wahlqvist M. L., Carlson L. A. Relationship in man between plasma free fatty acids and myocardial metabolism of carbohydrate substrates. Lancet 1971; ii: 448
   Google Scholar
• Lassers B. W., Wahlqvist M. L., Kaijser L., Carlson L. A. Effect of nicotinic acid on myocardial metabolism in man at rest and during exercise. J. appl. Physiol. 1972; 33: 72
   PubMed Web of Science ®Google Scholar
• Lundholm L., Mohme-Lundholm E., Vamos N. Lactic acid assay with L(+)lactic acid dehydrogenase from rabbit muscle. Acta physiol. scand. 1963; 58: 243
   PubMedGoogle Scholar
• Morgan H. E., Henderson M. J., Regen D. M., Park C. R. Regulation of glucose uptake in muscle. J. biol. Chem. 1961; 236: 253
   PubMed Web of Science ®Google Scholar
• Newsholme E. A., Randle P. J., Manchester K. L. Inhibition of the phosphofructokinase reaction in perfused rat heart by respiration of ketone bodies, fatty acids and pyruvate. Nature 1962; 193: 270
   PubMed Web of Science ®Google Scholar
• Opie H. L., Shipp J. D., Evans J. R., Le Boeuf B. Metabolism of glucose-U-C14 in perfused rat heart. Amer. J. Physiol. 1962; 203: 839
   PubMed Web of Science ®Google Scholar
• Pernow B., Saltin B. Availability of substrates and capacity for prolonged heavy exercise in man. J. appl. Physiol. 1971; 31: 416
   PubMed Web of Science ®Google Scholar
• Randle P. J., Newsholme E. A., Garland P. B. Regulation of glucose uptake by muscle. 8. Effect of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation on the uptake and metabolic fate of glucose in heart and diaphragm muscle. Biochem. J. 1964; 93: 652
   PubMed Web of Science ®Google Scholar
• Ruderman N. B., Toews C. J., Shafrir E. Role of free fatty acids in glucose homeostasis. Arch. int. Med. 1969; 123: 299
   PubMed Web of Science ®Google Scholar
• Schonfield G., Kipnis D. M. Effects of fatty acids on carbohydrate and fatty acid metabolism of rat diaphragm. Amer. J. Physiol. 1968; 215: 513
   PubMedGoogle Scholar
• Scott J. C., Finkelstein L. J., Spitzer J. J. Myocardial removal of free fatty acids under normal and pathological conditions. Amer. J. Physiol. 1962; 203: 482
   PubMed Web of Science ®Google Scholar
• Shipp J. C., Opie L. H., Challoner D. R. Fatty acid and glucose metabolism in the perfused rat heart. Nature 1961; 189: 1018
   Web of Science ®Google Scholar
• Svedmyr N., Harthon L., Lundholm L. The relationship between the plasma concentration of free nicotinic acid and some of its pharmacological effects in man. Clin. Pharmacol. Ther. 1969; 10: 559
   PubMed Web of Science ®Google Scholar
• Trout D. L., Estes E. H., Friedberg S. J. Titration of free fatty acids of plasma: a study of current methods and a new modification. J. Lipid Res. 1960; 1: 199
   PubMed Web of Science ®Google Scholar
• Wahlqvist M. L., Kaijser L., Lassers B. W., Löw H., Carlson L. A. The role of fatty acids and of hormones in the determination of myocardial carbohydrate metabolism in healthy fasting man. Europ. J. clin. Invest. 1973; 3: 57
   PubMed Web of Science ®Google Scholar