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Original Article

Conjugation, metabolism and excretion of [24-14 C] chenodeoxycholic acid in patients with extrahepatic cholestasis before and after biliary drainage-analysis of conjugated bile acids by HPLC

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Pages 157-164 | Received 04 Jun 1984, Accepted 21 Sep 1984, Published online: 08 Jul 2009

References

  • Eklund A, Norlander A, Norman A. Bile acid synthesis and excretion following release of total extrahepatic cholestasis by percutaneous transhepatic drainage. Eur J Clin Invest 1980; 10: 349–55
  • Hedcnborg G, Norlander A, Norman A. Bile acid excretion during drainage of extrahepatic cholestasis with rcfeeding of bile. Scand J Clin Lab Invest 1982; 42: 551–6
  • Hedenborg Norman G. A. The nature of urinary bile acid conjugates in patients with extrahepatic cholestasis. Scand J Clin Lab Invest 1984; 44: 725–33
  • Raedsch R, Lauterburg B H, Hofmann A F. Altered bile acid metabolism in primary biliary cirrhosis. Dig Dis Sci 1981; 26: 394–401
  • Stiehl A, Raedsch R, Rudolph G, Czygan P, Walker S. Analysis of bile acid glucuronides in urine: group separation on a lipophilic anion exchanger. Clin Chim Acta 1982; 123: 275–83
  • Parmentier G, Eyssen H. Synthesis and characteristics of the specific monosulfates of chenodeox-ycholatc, dcoxycholate and their taurine and glycine conjugates. Steroids. 1977; 30: 583–90
  • Hedenborg G, Norman A. Fasting and postprandial serum bile acid concentration with special reference to variations in the conjugate profile. Scand J Clin Lab Invest 1985; 45, (In press)
  • Hedenborg G, Norlander A, Norman A, Sund-blad R. Conjugation and excretion of l4C chenodeoxycholic acid during total extrahepatic cholestasis. Scand J Clin Lab Invest 1982; 42: 557–61
  • Goto J, Saito M, Chikai T, Goto N, Nambara T. Determination of serum bile acids by high-performance liquid chromatography with fluorescence labelling. J Chromatogr 1983; 276: 289–300
  • Hasegawa S, Uenoyama R, Takeda I, et al. A highly sensitive determination of individual serum bile acids using high-performance liquid chromatography with immobilized enzyme. J Chromatogr 1983; 278: 25–34
  • Goto J, Kato H, Kaneko K, Nambara T. High-performance liquid chromatographic behaviour of sulfated bile acids. J Liquid Chromatogr 1981; 4: 1351–9
  • Goto J, Kato H, Nambara T. Separation of monosulfated bile acids by high-performance liquid chromatography. J Liquid Chromatogr 1980; 3: 645–55
  • Goto J, Kato H, Saruta Y, Nambara T. Separation and determination of bile acid 3-sulfates in human bile by high-performance liquid chromatography. J Chromatogr 1981; 226: 13–24
  • Mingrone G, Greco A V, Boniforti L, Passi S. Analysis of conjugated bile acids by high performance liquid chromatographv and mass spectrometry. Lipids 1983; 18: 90–5
  • Fromm H, Farivar S, Carlson G L, Hofmann A F, Amin P. Hepatic formation of ursodeoxycholic acid and chenodeoxycholic acid from 7-kctolithocholic acid in man. Gastroenterology 1977; 73: 1221–4
  • Bremmclgaard A, Sjovall J. Hydroxylation of cholic, chenodeoxycholic and deoxycholic acids in patients with intrahepatic cholestasis. J Lipid Res 1980; 21: 1072–81
  • Summerficld J A, Billing B H., Stackleton C HL. Identification of bile acid in serum and urine in cholestasis. Biochem J 1976; 154: 507–16
  • Alme B, Sjovall J. Analysis of bile acid glucuronides in urine. Identification of 3α, 6α, 12α-trihydroxy-5β-cholamc acid. J Steroid Biochem 1980; 13: 907–16
  • Takikawa H, Otsuka H, Beppu T, Seyama Y, Yamaa T. Serum concentrations of bile acid glucuronides in hepatobiliary diseases. Digestion 1983; 27: 189–195
  • van Berge Hencgouwen G P, Brandt K H, Eyssen H, Parmentier G. Sulphated and unsulphated bile acids in serum, bile and urine of patients with cholestasis. Gut 1976; 17: 861–9
  • Corbett C L, Bartholomew T C, Billing B H, Sum-mcrfield J A. Urinary excretion of bile acids in cholestasis: Evidence for renal tubular secretion in man. Clin Sci 1981; 61: 773–80

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