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Original Article

L-Carnitine and haemodialysis

Double blind study on muscle function and metabolism and peripheral nerve function

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Pages 169-178 | Received 13 Jun 1984, Accepted 02 Oct 1984, Published online: 08 Jul 2009

References

  • Battistella P A, Angelini C, Vergani L, Bertoli M, Lorenzi S. Carnitine deficiency induced during haemodialysis. Lancet 1978; i: 939
  • Böhmer T, Bergrem H, Eiklid K. Carnitine deficiency induced during intermittent haemodialysis for renal failure. Lancet 1978; i: 126–8
  • Mingardi G, Bizzi A, Cini M, Licini R, Mecca G, Garattini S. Carnitine balance in hemodialysed patients. Clin Nephrology 1980; 6: 269–70
  • Moorthy A V, Rosenblum M, Rajaram R, Shug A L. A comparison of plasma and muscle carnitine levels in patients on peritoneal or hemodialysis for chronic renal failure. Am J Nephrol 1983; 3: 205–8
  • Albertazzi A, Spisni C, Del Rosso G, Palmieri P F, Rossini P M. Electromyographic changes induced by oral carnitine treatment in dialysis patients. Proc Clin Dialysis Transpl Forum 1980; 10: 1–6
  • Bertoli M, Battistella P A, Vergani L, et al. Carnitine deficiency induced during hemodialysis and hyperlipidemia: effect of replacement therapy. Am J Clin Nutr 1981; 8: 1496–1500
  • Guarnieri G F, Ranieri F, Toigo G, et al. Lipid-lowering effect of carnitine in chronically uremic patients treated with maintenance hemodialysis. Am J Clin Nutr 1980; 33: 1489–92
  • Penn D, Schmidt-Sommerfeld E. Carnitine and carnitine esters in plasma and adipose tissue of chronic uremic patients undergoing hemodialysis. Metabolism 1983; 8: 806–9
  • Bellinghieri G, Savica V, Mallamace A, et al. Correlation between increased serum and tissue I-carnitine levels and improved muscle symptoms in hemodialyzed patients. Am J Clin Nutr 1983; 38: 523–31
  • Fagher B, Thysell H, Nilsson-Ehle P, et al. The effect of D, L-carnitine supplementation on muscle metabolism, neuropathy, cardiac and hepatic function in hemodialysis patients. A pilot study. Acta Med Scand 1982; 212: 115–20
  • Bergström J. Percutaneous needle biopsy of skeletal muscle in physiological and clinical research. Scand J Clin Lab Invest 1975; 35: 609–16
  • Cederblad G, Lindstedt S. A method for the determination of carnitine in the picomole range. Clin Chim Acta 1972; 37: 235–43
  • Cederblad G, Finnström O, Mårtensson J. Urinary excretion of carnitine and its derivatives in newborns. Biochem Med 1982; 27: 260–5
  • Harris R C, Hultman E, Nordesjo L-O. Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values. Scand J Clin Lab Invest 1974; 33: 109–20
  • Hislop H J, Perrine J J. The isokinetic concept of exercise. Physical Therapy 1967; 47: 114–7
  • Thorstensson A, Karlsson J. Fatiguability and fibre composition of human skeletal muscle. Acta Physiol Scand 1976; 98: 318–22
  • Spink C, Wadsö I. Calorimetry as an analytical tool in biochemistry and biology. Methods in biochemical analysis, D Glick. Wiley-Interscience, New York 1976; 23: 1–159
  • Wadsö I. A microcalorimeter for biological analysis. Science Tools 1974; 21: 18–21
  • Wadso I. Some problems in calorimetric measurements on cellular systems. Biological microcalorimetry, A E Beezer. Academic Press, London, New York 1980; 247–74
  • Lundholm K, Bylund A-C, Holm J, Smeds S, Schersten T. Metabolic studies in human skeletal muscle tissue. Evaluation of an in vitro preparation intended for clinical metabolic studies. Eur Surg Res 1975; 7: 65–82
  • Goldberg J M, Lindblom U. Standardised method of determining vibratory perception thresholds for diagnosis and screening in neurological investigation. J Neurol Neurosurg Psychiatry 1979; 42: 793–803
  • Fruhstorfer H, Lindblom U, Schmidt W G. Method for quantitative estimation of thermal thresholds in patients. J Neurol Neurosurg Psychiatry 1976; 39: 1071–5
  • Borges O, Ericsson M, Essen B, Nordesjo L O, Nordgren B, Stalberg E M. vastus lat.-physiology, morphology, histochemistry. Changes with age. IRMA Congress, Puerto Rico. 1982
  • Larsson L. Morphological and functional characteristics of the ageing skeletal muscle in man. A cross-sectional study. Acta Physiol Scand 1978; 457(Suppl)1–36
  • Savica V, Bellinghieri G, Di Stefano C, et al. Plasma and muscle carnitine levels in haemodialysis patients with morphological-ultrastructural examination of muscle samples. Nephron 1983; 35: 232–6
  • Genuth S M, Hoppel C L. Plasma and urine carnitine in diabetic ketosis. Diabetes 1979; 28: 1083–7
  • Frohlich J, Seccombe D W, Hahn P, Dodek P, Hynie I. Effect of fasting on free and esterified carnitine levels in human serum and urine: correlation with serum levels of free fatty acids and β-hydroxybutyrate. Metabolism 1978; 27: 555–61
  • Cederblad G, Hermansson G, Ludvigsson J. Plasma and urine carnitine in children with diabetes mellitus. Clin Chim Acta 1982; 125: 207–17
  • Vacha G M, Giorcelli G, Siliprandi N, Corsi M. Favorable effects of 1-carnitine treatment on hypertriglyceridemia in hemodialysis patients: decisive role of low levels of high-density lipoprotein-cholesterol. Am J Clin Nutr 1983; 38: 532–40
  • Cederblad G, Lindstedt S, Lundholm K. Concentration of carnitine in human muscle tissue. Clin Chim Acta 1974; 53: 311–21
  • Chinet A, Clausen T, Girardier L. Microcalori-metric determination of energy expenditure due to active sodium-potassium transport in the soleus muscle and brown adipose tissue of the rat. J Physiol 1977; 265: 43–61
  • Ponce-Hornos J E, Ricchiuti N V, Langer G A. On-line calorimetry in the arterially perfused rabbit interventricular septum. Am J Physiol 1982; 243: H289–95
  • Biological microcalorimetry, A E Beezer. Academic Press, London, New York 1980
  • Biochemical thermodynamics, M N Jones. Elsevier, Amsterdam 1979
  • Tyler H R. Neurological aspects of dialysis patients. Replacement of renal function by dialysis, W Drukker, F M Parsons, J F Maher. Nijhoff Publishers, The Hague 1979; 601–12

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