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Original Article

Evaluation and quality control of a monoclonal antibody based enzyme antigen immunoassay of acetylcholinesterase in amniotic fluid

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Pages 503-511 | Received 24 Aug 1988, Accepted 25 Jan 1989, Published online: 08 Jul 2009

References

  • Report of the Collaborative Acetylcholinesterase Study. Amniotic fluid acetylcholinesterase electrophoresis as a secondary test in the diagnosis of anencephaly and open spina bifida in early pregnancy. Lancet 1981; ii: 321–4
  • Smith A D, Wald N J, Cuckle H S, Stirrat G M, Bobrow M, Lagercrantz H. Amniotic-fluid acetylcholinesterase as a possible diagnostic test for neural-tube defects in early pregnancy. Lancet 1979; i: 685–8
  • Norgaard-Pedersen B, Hangaard J, Bjerrum O J. Quantitative enzyme antigen immunoassay of acetylcholinesterase in amniotic fluid. Clin Chem 1983; 29: 1061–4
  • Brock D JH, Barron L, van Heyningen V. Prenatal diagnosis of neural-tube defects with a monoclonal antibody specific for acetylcholinesterase. Lancet 1985; i: 5–8
  • Bonham J R, Atack J R. A neural tube defect specific form of acetylcholinesterase in amniotic fluid. Clin Chim Acta 1983; 135: 233–7
  • Rasmussen A G, Sorensen K, Selmer J, et al. Immunochemical determination of acetylcholinesterase in amniotic fluid–An evaluation of eleven monoclonal antibodies. Clin Chim Acta 1987; 166: 17–25
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  • Chubb I W, Pilowsky P M, Springell H J, Pollard A C. Acetylcholinesterase in human amniotic fluid: An index of fetal neural development?. Lancet 1979; i: 688–90
  • Brock D JH, Barlow R D, Wald N J, et al. Fetal calf serum as cause of false positive amniotic fluid acetylcholinesterase gel tests. Lancet 1982; ii: 1044
  • Barlow R D, Cuckle H S, Wald N J. The identification of false-positive amniotic fluid acetylcholinesterase results due to fetal calf serum contamination. Brit J Obstet Gynaecol 1984; 91: 986–8
  • Wald N J, Cuckle H S, Barlow R D, et al. Early antenatal diagnosis of exomphalos. Lancet 1980; i: 1368–9
  • Appleyard M E, Smith A D, Wilcock G K, Esiri M M. Decreased CSF acetylcholinesterase activity in Alzheimer's disease. Lancet 1983; ii: 452
  • Appleyard M E, Smith A D. In vitro release of acetylcholinesterase from Auerbach's plexus of guinea-pig ileum. Br J Pharmacol 1987; 92: 530P

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