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Original Article

Effects of nicotinic acid treatment on fatty acid composition of plasma lipids and adipose tissue in hyperlipidaemia

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Pages 547-553 | Received 12 Jul 1991, Accepted 25 Feb 1992, Published online: 08 Jul 2009

References

  • Carlson L A. Nicotinic acid: its metabolism and its effects on plasma free fatty acids. Metabolic effects of nicotinic acid and its derivatives, KF Gey, LA Carlson. Hans Huber, Berns 1971; 157–65
  • Walldius G. Fatty acid incorporation into human adipose tissue (FIAT) in hypertrigleridemia. Methodological, clinical and experimental studies. Acta Med Seand 1976, Suppl 591
  • Solyom A, Puglisi L. Effect in vitro in nicotinic acid on triglyccridcs synthesis in rat adipose tissue. Biochem Pharmacol 1966; 15: 41–8
  • Keys A, Anderson J T, Grande F. Scrum cholesterol response to changes in the diet. IV. Particular saturated fatty acids in the diet. Metabolism 1965; 14: 776–87
  • Vesshy B, Gustafsson I-B, Bobcrg J, Karlström B, Lithell H, Werner I. Substituting polyunsaturated for saturated fat as a single change in a Swedish diet: effects on serum lipoprotein metabolism and glucose tolerance in patients with hyperlipo-proteinemia. Eur J Clin Invest 1980; 120: 193–202
  • Weisweller P, Janetschek P, Schwandt P. Influence of polyunsaturated fats and fat restriction on serum lipoproteins in humans. Metabolism 1985; 34: 83–7
  • Gustafsson I B, Vessby B, Karlström B, Boberg J, Boberg M, Lithell H. Effects on the serum lipoprotein concentrations by lipid-lowering diets with different fatty acid compositions. J Am Coll Nutr 1985; 4: 241–8
  • Leaf A, Weber P C. Medical Progress. Cardiovascular effects of n-3 fatty acids. N Engl J Med 1988; 318: 549–57
  • Schrade W, Biegler R, Böhle E. Fatty-acid distribution in the lipid fractions of healthy persons of different age patients with atheroslcerosis and patients with idiopathic hyperlipidaemia. J Atheroscler Res 1961; 1: 47–61
  • Logan R L, Riemersma R A, Thomson M, Oliver M F, Olsson A G, Walldius G, Rössner S, Kaijser L, Callmer E, Carlson L A, Lockerbie L, Lutz W. Risk factors for ischaemic heart-disease in normal men aged 40. Lancet 1978; i: 949–55
  • Jurand J, Oliver M F. The effects of ethyl chloro-phenoxyisobutyrate on serum cholesteryl triglycerie and phospholipid fatty acids. J Atheroscler Res 1963; 3: 547–53
  • Vessby B, Lithell H, Gustafsson I-B, Boberg J. Changes in the fatty acid composition of the plasma lipid esters during lipid-lowering treatment with diet clofibrate and niceritrol. Atherosclerosis 1980; 35: 51–65
  • Vessby B, Lithell H, Hellsing K, Östlund-Lindqvist A-M, Gustafsson I-B, Boberg J, Ledermann H. Effects of bezafibrate on the serum lipoprotein lipid and apoliprotein composition lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis 1980; 37: 257–69
  • Fletcher M J. A calorimetric method for estimating serum triglycerides. Clin Chim Acta 1968; 22: 393–7
  • Zlatkis A, Zak B, Boyle J. A new method for direct determination of serum cholesterol. J Lab Clin Med 1953; 41: 486–92
  • Carlson K. Lipoprotein fractionation. J Clin Path 1973; 26: 32–7, (Suppl 5)
  • Folch J, Lees M, Stanley G HS. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957; 226: 497–509
  • Carlson L A. Determination of scrum triglycerides. J Atheroscler Res 1963; 3: 334–6
  • Olsson A G, Walldius G, Rössner S, Callmer E, Kaijser L. Studies on serum lipoproteins and lipid metabolism. Analysis of a random sample of 40-year-old men. Acta Med Scand 1980, Suppl 637
  • Snedecor G, Cochran WG. Statistical Methods. 7th Edition. The Iowa State University Press, Ames, IowaUSA 1980
  • Hirsch J, Farquhar J W, Ahrens EH, Jr, Peterson M L, Stoffel W. Studies of adipose tissue in man. A microtcchnic for sampling and analysis. Am J Clin Nutr 1960; 8: 499–511
  • Beynen A C, Hermus R JJ, Hautvast J GAJ. A mathematical relationship between the fatty acid composition of the diet and that of the adipose tissue in man. Am J Clin Nutr 1980; 33: 81–5
  • Kudchotkar B J, Sodhi H S, Horlick L, Mason D T. Mechanisms of hypolipidemic action of nicotinic acid. Clin Pharmacol Ther 1978; 24: 354–73
  • Grundy S M, Mok H YI, Zech L, Berman M. Influence of nicotinic acid on metabolism of cholesterol and triglyceride in man. J Lipid Res 1981; 24–36
  • Walldius G, Rössner S. Effects of nicotinic acid on the intravenous fat tolerance test (IVFTT) and fatty acid incorporation into adipose tissue (FIAT) in hypertriglerceridemia (HTG). Fifth international symposium on drugs affecting lipid metabolism, D Kritchewsky, R Paoletti, WL Holmes. Plenum Press, New York 1975; 491, (Abstract)
  • Kaijser L, Eklund B, Olsson A G, Carlson L A. Dissociation of the effects of nicotinic acid on vasodilatation and lipolysis by a prostaglandin synthesis inhibitor indomethacin in man. Med Biol 1979; 57: 114–7
  • Olsson A G, Carlson L A, Änggård ER, Ciabattoni G. Prostacyclin production augmented in the short term by nicotinicacid. Lancet 1983; ii: 565–6
  • Carlson L A. The effect of nicotinic acid treatment on the chemical composition of plasma lipoprotein classes in man. Drugs affecting lipid metabolism. Advances in Experimental Medicine and Biology 1969; 4: 327–38
  • Beaumont J-L, Carlson L A, Cooper G R, Pfciffer Z, Fredrickson D S, Strasser T. Classification of hyperlipidaemias and hypcrlipoproteinaemias. Bull Wld Hit Org 1970; 43: 891–915

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