Development of molecular genetic methods for monitoring myeloid malignancies

References

• Borrow J, Goddard A D, Sheer D, Solomon E. Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17. Science 1990; 249: 1577–80
   PubMed Web of Science ®Google Scholar
• vonLindern M, Poustka A, Lerach H, Grosveld G. The (6;9) chromosome translocation, associated with a specific subtype of acute non-lymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34. Mol Cell Biol 1990; 10: 4016–26
   Google Scholar
• vonLindern M, Fornerod M, van Baal S, Jaegle M, de Wit T, Buijs A, Grosveld G. The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. Mol Cell Biol 1992; 12: 1687–97
   Google Scholar
• Baylin S B, Makos M, Wu J, Chiu Yen R-W, de Bustros A, Vertino P, Nelkin B D. Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression. Cancer Cells 1991; 3: 383–90
   PubMed Web of Science ®Google Scholar
• deBustros A, Nelkin B D, Silverman A, Erlich G, Poiesz B, Baylin S B. The short arm of chromosome 11 is a “hot spot” for hypermethylation in human neoplasia. Proc Natl Acad Sci USA 1988; 85: 5693–7
   PubMed Web of Science ®Google Scholar
• Baylin S B, Fearon E R, Vogelstein B, de Bustros A, Sharkis S J, Burke P J, Staal S P, Nelkin B. D. Hypermethylation of the 5′ region of the calcitonin gene is a property of human lymphoid and acute Myeloid malignancies. Blood 1987; 70: 412–7
   PubMed Web of Science ®Google Scholar
• Baylin S B, Hoppener J WM, de Bustros A, Steenberg P H, Lips C JM, Nelkin B D. DNA methylation patterns of the calcitonin gene in human cancers and lymphomas. Cancer Res 1986; 46: 2917–22
   PubMed Web of Science ®Google Scholar
• Broad P M, Symes A J, Thakker R V, Craig R K. Structure and methylation of human calcitonin/ α-CGRP gene. Nucleic Acids Res 1989; 17: 6999–7011
   PubMedGoogle Scholar
• Malinen T, Palotie A, Pakkala S, Peltonen L, Ruutu T, Jansson S-E. Acceleration of chronic myeloid leukemia correlates with calcitonin geze hypermethylation. Blood 1991; 77: 2435–40
   PubMed Web of Science ®Google Scholar
• Nelkin B D, Przepiorka D, Burke P J, Thomas E D, Baylin S B. Abnormal methylation of the calcitonin gene marks progression of chronic myelogenous leukemia. Blood 1991; 77: 2431–4
   PubMed Web of Science ®Google Scholar
• Ihalainen J, Pakkala S, Savolainen E R, Jansson S-E, Palotie A. The myelodysplastic syndromes are characterized by calcitonin hypermethylation. Leukemia, in press
   Google Scholar
• Adams R LP. DNA methylation. The effect of minor bases on DNA-protein interactions. Biochem J 1990; 265: 309–20
   PubMed Web of Science ®Google Scholar
• Bestor T H. DNA methylation: evolution of a bacterial immune function into a regulator of gene expression and genome structure in higher eukaryotes. Philos Trans R Soc Lond Biol Sci 1990; 326: 179–87
   PubMed Web of Science ®Google Scholar
• Burdon R H, Qureshi M, Adams R LP. Nuclear matrix-associated DNA methylase. Biochem Biophys Acta 1985; 825: 70–9
   Google Scholar
• Singer-Sam J, Grant M, Lebon J M, Okuyama K, Chapman V, Monk M, Riggs A D. Use of a HpaII-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG Island of mouse embryos at the time of X-chromosome inactivation. Mol Cell Biol 1990; 10: 4987–89
   PubMed Web of Science ®Google Scholar
• Singer-Sam J, LeBon J M, Tanguay R L, Riggs A D. A quantitative Hpall-PCR assay to measure methylation of DNA from a small number of cells. Nucleic Acids Res 1990; 18: 687
   PubMed Web of Science ®Google Scholar
• Bos J L, Verlaan-De Vries M, van der Eb A J, Janssen J WG, Delwel R, Löwenberg B, Colly L P. Mutations in N-ras predominate in acute myeloid leukemia. Blood 1987; 69: 1237–41
   PubMed Web of Science ®Google Scholar
• Bar-Eli M, Ahuja H, Gonzales-Cadavid N, Foti A, Cline M J. Analysis of N-ras exon-1 mutations in myelodysplastic syndromes by polymerase chain reaction and direct sequencing. Blood 1989; 73: 281–3
   PubMed Web of Science ®Google Scholar
• Ahuja H G, Foti A, Bar-Eli M, Cline M J. The pattern of mutational involvement of ras genes in human hematologic malignancies determined by DNA amplification and direct sequencing. Blood 1990; 75: 1684–90
   PubMed Web of Science ®Google Scholar
• Farr C J, Saiki R K, Erlich H A, McCormick F, Marshall C J. Analysis of ras gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes. Proc Natl Acad Sci (Wash) 1988; 85: 1629–33
   PubMed Web of Science ®Google Scholar
• Hirai H, Kobayashi Y, Mano H, Hagiwara K, Maru Y, Omine M, Mizoguchi H, Nishida J, Takaku F. A point mutation at codon 13 of the N-ras oncogene in myelodysplastic syndrome. Nature (Lond) 1987; 327: 430–2
   PubMed Web of Science ®Google Scholar
• Needleman S W, Kraus M H, Srivastava S K, Levine P H, Aaronson S A. High frequency of N-ras activation in acute myelogeneous leukemia. Blood 1986; 67: 753–7
   PubMed Web of Science ®Google Scholar
• Lyons J, Janssen J WG, Bartram C, Lay ton M, Mufti G J. Mutation of Ki-ras and N-ras oncogenes in myelodysplastic syndromes. Blood 1988; 71: 1707–12
   PubMed Web of Science ®Google Scholar
• Radich J P, Kopecky K J, Willman C L, Weick J, Head D, Appelbaum F, Collins S J. N-ras mutations in adult de novo acute myelogenous leukemia: prevalence and clinical significance. Blood 1990; 76: 801–7
   PubMed Web of Science ®Google Scholar
• Syvänen A-C, Aalto-Setälä K, Harju L, Kontula K, Söderlund H. A primer-guided nucleotide incorporation assay in the genotyping of apolipo-protein E. Genomics 1990; 8: 684–92
   PubMed Web of Science ®Google Scholar
• Syvänen A-C, Söderlund H, Laaksonen E, Bengtström M, Turunen M, Palotie A. N-ras gene mutations in acute myeloid leukemia: accurate detection by solid-phase minisequencing. Int J Cancer 1992; 50: 713–8
   Google Scholar
• Lübbert M, Mirro J, Jr, Miller C W, Kahan J, Isaac G, Kitchingman G, Mertelsman R, Herrmann F, McCormick F, Koeffher H P. N-ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis. Blood 1990; 75: 1163–9
   PubMed Web of Science ®Google Scholar