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Original Article

Prevention of trypsin-induced shock in rats by the pancreatic secretory trypsin inhibitor

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Pages 595-599 | Received 08 Apr 1994, Accepted 25 Jun 1994, Published online: 08 Jul 2009

References

  • Greene L J., Rigbi, Fackre D S. Trypsin inhibitor from bovine pancreatic juice. J Biol Chem 1966; 241: 5610–18
  • Eddeland A, Wehlin L. Secretin-cholecystokinin-stimulated secretion of trypsin and trypsin inhibitor in pure human pancreatic juice collected by endoscopic retrograd catheterization. Hoppe-Seyler's Z Physiol Chem 1978; 359: 1653–8
  • Ohisson K. Acute pancreatitis. Biochemical, pathophysiological and therapeutics aspects. Acta Gastroenterol Belg 1988; 51: 3–12
  • Ohisson K, Olsson R, Björk P, et al. Local administration of human pancreatic secretory trypsin inhibitor prevents the development of experimental acute pancreatitis in rats and dogs. Scand J Gastroenterol 1989; 24: 693–704
  • Ohisson K, Ganrot P-O, Laurell C-B. In vivo interaction between trypsin and some plasma proteins in relation to tolerance to intravenous infusion of trypsin in dog. Acta Chir Scand 1971; 137: 113–21
  • Ohisson K. Influence of the human pancreatic secretory trypsin inhibitor on trypsin-induced C3 and kininogen cleavage: an in vitro study. Scand J Gastroenterol 1986; 21(suppl 126)18–20
  • Trapnell J E., Rigby C C., Talbot C H., Duncan E HL. A controlled trial of Trasylol in the treatment of acute pancreatitis. Br J Surg 1974; 61: 177–82
  • MRC Multicentre Trial. Death from acute pancreatitis. Lancet 1977; 2: 632–5
  • Büchler M, Malfertheiner P, Uhl W, et al. The german multicenter doubleblind randomized study of gabex-ate-mesilate (4g/day i.v.) in acute pancreatitis. 1990; 98, part 2, 214 Abstract. Gastroenterology
  • Harada H, Miyake H, Ochi K, Tanaka J, Kimura I. Clinical trial with a protease inhibitor gabexate mesilate in acute pancreatitis. Int J Pancreatol 1991; 9: 75–9
  • Taenaka N, Shimada Y, Hirata T, et al. Gabexate mesilate (FOY) therapy of disseminated intravascular coagulation due to sepsis. Crit Care Med 1983; 11: 735–8
  • Akashi K, Ischimaru T, Shibuya T, Harada M, Niho Y. Human urinary proteinase inhibitor in the treatment of P carinii pneumonia. Chest 1991; 99: 1055–6
  • Wakayama S, Suzuki T, Sakai T, Matsuki A. Effect of nafamostat mesilate on serum activities of pancreatic enzymes and plasma hormone levels. Masui 1990; 39: 734–40
  • Erlanger B F., Kokowsky N, Cohen W. The preparation and properties of two new chromogenic substrates of trypsin. Arch Biochem Biophys 1961; 95: 271–8
  • Mancini G, Carbonara A O., Heremans J F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 1965; 2: 235–54
  • Eddeland A, Ohisson K. Purification and immunochemical quantitation of human pancreatic secretory trypsin inhibitor. Scand J Clin Lab Invest 1978; 38: 261–7
  • Laurell C-B. Electroimmuno assay. Scand J Clin Lab Invest 1972; 29(Suppl 124)21–37
  • Ganrot P O. Crossed immunoelectrophoresis. Scand J Clin Lab Invest (Suppl 124) 1972; 29: 39–41
  • Gauthier F, Genell S, Mouray H, Ohisson K. Interactions in vitro, in vivo between rat serum protease inhibitors and anodal and cathodal rat trypsin and chymotrypsin. Biochim Biophys Acta 1979; 566: 200–10
  • Sottrup-Jensen L. α-Macroglobulins: structure, shape, and mechanism of proteinase complex formation. J Biol Chem 1989; 264: 11539–42
  • Lasson Å, Ohisson K. An in vitro study of the influence of plasma protease inhibitors and aprotinin on trypsin-induced C3 cleavage in human serum. Biochim Biophys Acta 1982; 709: 227–33
  • Koj A, Magielska-Zero D, Kurdowska A, Bereta J. Proteinase inhibitors as acute phase reactants: Regulation of synthesis and turnover. Adv Exp Med Biol 1988; 240: 171–81
  • Schweitz H, Vincent J P., Lazdunski M. Trypsin-pancreatic secretory inhibitor (Kazal inhibitor) interaction. Kinetic and thermodynamic properties. Biochemistry 1973; 12: 2841–6
  • Balldin G, Gustafsson E-L, Ohisson K. Influence of plasma protease inhibitors and Trasylol on trypsin-induced bradykinin-release in vitro, in vivo. Eur Surg Res 1980; 12: 260–9
  • Williams J C., Falcone R C., Do M LT, Lindstrom D D., Howe B B. Acute blood pressure effects of selected serine proteases in normotensive rats and dogs. Pharmacology 1991; 43: 199–209
  • Bieth J G. Pathophysiological interpretation of kinetic constants of protease inhibitors. Bull Eur Physiopath Resp 1980; 16(suppl.)183–95
  • Vincent J-P, Lazdunski M. Trypsin-pancreatic trypsin inhibitor association. Dynamics of the interaction and role of disulfide bridges. Biochemistry 1972; 11: 2967–77
  • Eddeland A, Ohisson K. Purification of canine pancreatic secretory trypsin inhibitor and interaction in vitro with complexes of trypsin-a-macroglobulin. Scand J Clin Lab Invest 1976; 36: 815–20
  • Balldin G, Borgström A, Marks W H., Ohisson K. On the role of the pancreatic secretory trypsin inhibitor as an inactivator of trypsin-α2-macroglobulin complexes in acute pancreatitis. Hoppe-Seyler's Z Physiol Chem 1984; 365: 751–6
  • Davidsen O, Christiansen E L., Gliemann J. The plasma clearance of human (macog'obulin-trypsin complex in the rat is mainly accounted for by uptake into hepatocytes. Biochim Biophys Acta 1985; 846: 85–92
  • Chen H-Q, Yan L-N, Li L, Zhong G-H, Wu H-G. Alteration in viscoelasticity of whole blood from dogs with experimental acute necrotizing pancreatitis. Clin Hemorheol 1991; 11: 25–33

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