Docosahexaenoic acid induces lipid accumulation in myocardial cells of rats

References

• Phillipson B E., Rothrock D W., Connon W E., Harris W S., Illingworth D R. Reduction of plasma lipids, lipoproteins and apoproteins by dietary fish oils in patients with hypertriglyceridemia. N Eng J Med 1985; 312: 1210–16
   PubMed Web of Science ®Google Scholar
• Harris W S., Connor W E., Murphy M P. The comparative reductions of the plasma lipids and lipoproteins by dietary polyunsaturated lipids and lipoproteins by dietary polyunsaturated fats: salmon oil versus vegetable oils. Metabolism 1983; 32: 179–84
   PubMed Web of Science ®Google Scholar
• Nossen J Ø, Rustan A C., Gloppestad S H., Malbak-ken S, Drevon C A. Eicosapentaenoic acid inhibits synthesis and secretion of triacylglycerols by cultured rat hepatocytes. Biochim Biophys Acta 1986; 879: 56–65
   PubMed Web of Science ®Google Scholar
• Sanders T AB, Sullivan D R., Reeve J, Thompson G R. Triglyceride-lowering effect of marine polyunsaturates in patients with hypertriglyceridemia. Arteriosclerosis 1985; 5: 459–65
   PubMedGoogle Scholar
• Nestel P J., Connor W E., Reardon M G., Connor S, Boston R. Suppression by diets rich in fish oil of very low density lipoprotein production in man. J Clin Invest 1984; 74: 82–9
   PubMed Web of Science ®Google Scholar
• Gudbjarnason S, Oskarsdottir G. Modification of fatty acid composition of rat heart lipids by feeding cod liver oil. Biochim Biophys Acta 1976; 487: 10–15
   Google Scholar
• Swanson J E., Kinsella J E. Dietary n-3 polyunsaturated fatty acids: Modification of rat cardiac lipids and fatty acid composition. J Nutr 1986; 116: 514–23
   PubMed Web of Science ®Google Scholar
• Nalbone G, Termine E, Leonardi J, Portugal H, Lechene P, Calaf R, Lafont R, Lafont H. Effect of dietary salmon oil feeding on rat heart lipid status. J Nutr 1988; 118: 809–17
   PubMed Web of Science ®Google Scholar
• Charnock J S., Turner J, McIntosh G H. The occurrence of cardiac lipidosis and necrotic lesions in the hearts of rats following long-term feeding of different lipid supplemented diet. J Nutr Sc Vitami-nol 1987; 33: 75–87
   PubMed Web of Science ®Google Scholar
• Christiansen E N., Flatmark T, Kryvi H. Effects of marine oil diet on peroxisomes and mitochondria of rat liver. A combined biochemical and morpho-metric study. Eur J Cell Biol 1981; 26: 11–20
   PubMed Web of Science ®Google Scholar
• Berge R K., Nilsson A, Husoy A M. Rapid stimulation of liver palmitoyl-CoA synthetase, carnitine palmitoyltransferase and glycerophosphate acyl-transferase compared to peroxisomal β-oxidation and palmitoyl-CoA hydrolase in rats fed high-fat diets. Biochim Biophys Acta 1988; 960: 417–26
   PubMed Web of Science ®Google Scholar
• Hexeberg S, Willumsen N, Rotevatn S, Hexeberg E, Berge R K. Cholesterol induced lipid accumulation in myocardial cells of rats. Cardiovasc Res 1993; 27: 442–46
   PubMed Web of Science ®Google Scholar
• Small G M., Burdett K, Kannock M J. A sensitive spectrophotometry assay for peroxisomal acyl-CoA oxidase. Biochem J 1985; 227: 205–10
   PubMed Web of Science ®Google Scholar
• Berge R K., Farstad M. Dual localization of long-chain acyl-CoA hydrolase in rat liver: one in the microsomes and one in the mitochondrial matrix. Eur J Biochem 1979; 95: 89–97
   PubMedGoogle Scholar
• Kramer J KG, Hulan H W. A comparison of procedures to determine free fatty acids in rat heart. J Lipid Res 1978; 19: 103–6
   PubMed Web of Science ®Google Scholar
• Abdelatíf A M., Vies R O. Pathological effects of dietary rapeseed oil in rats. Nutr Metabol 1970; 12: 285–95
   PubMedGoogle Scholar
• Beare-Rogers J L., Nera E A., Heggtveit H A. Cardiac lipid changes in rats fed oils containing long-chain fatty acids. Can Inst Food Technol J 1971; 4: 120–4
   Web of Science ®Google Scholar
• Roquelin G, Sergiel J P., Martin B, Lecler J, Cluzon R. The nutritive value of refined rapeseed oils: A review. J Am Oil Chem Soc 1971; 48: 728–32
   Web of Science ®Google Scholar
• Borg K. Physiopathological effects of rapeseed oil: A review. Acta Med Scand (Suppl) 1975; 585: 5
   PubMedGoogle Scholar
• Willumsen N, Skorve J, Hexeberg S, Rustan A, Berge R. The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis. Lipids 1993; 28: 683–90
   PubMed Web of Science ®Google Scholar
• Willumsen N, Hexeberg S, Skorve S, Lundquist M, Berge R K. Docosahexaenoic acid shows no triglyceride lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats. J Lipid Res 1993; 34: 13–22
   PubMed Web of Science ®Google Scholar
• Maunsbach A B., Wirsen C U. Ultrastructural changes in kidney, myocardium and skeletal muscle of the dog during excessive mobilization of free fatty acids. J Ultrastruct Res 1966; 16: 35–54
   PubMedGoogle Scholar
• Crass M F., III. Myocardial triacylglycerol metabolism in ischemia. Tex Rep Biol 1979; 39: 439–52
   PubMedGoogle Scholar
• Stein O, Stein Y. Lipid synthesis, intracellular transport, and storage III. Electron microscopic radioautographic study of the rat heart perfused with triated oleic acid. J Cell Biol 1968; 36: 63–77
   Web of Science ®Google Scholar
• Ward B J., Gloster J A., Harris P. The incorporation and distribution of 3H oleic acid in the isolated perfused guinea-pig heart: a biochemical and EM autoradiographic study. Tissue Cell 1979; 11: 793–801
   PubMed Web of Science ®Google Scholar
• Jodalen H, Stangeland L, Grong K, Vik-Mo H, Lekven J. Lipid accumulation in the myocardium during acute regional ischaemia in cats. J Mol Cell Cardiol 1985; 19: 973–80
   Google Scholar
• Mackezie C G., Mackenzie J B., Reiss O K., Philott D E. Regulation of cell lipid metabolism and accumulation. IV. The isolation and composition of cytoplasmic lipid-rich particles. Biochem 1966; 5: 1454–61
   PubMed Web of Science ®Google Scholar
• Opie L H. Metabolism of the heart in health and disease. Am Heart J 1968–1969; 76: 685–98, 77: 100–22; 77: 383–410
   PubMed Web of Science ®Google Scholar
• Brownsey E W., Brunt R V. The effect of adrenaline-induced endogenous lipolysis upon the mechanical and metabolic performance of ischaemically perfused rat hearts. Clin Sc Mol Med 1977; 53: 513–21
   PubMedGoogle Scholar
• Kjekshus J K., Mjøs O D. Effect of free fatty acids on myocardial function and metabolism in the ischaemic dog heart. J Clin Invest 1972; 51: 1767–76
   PubMed Web of Science ®Google Scholar
• Liedtke A J., Nellis S, Neely J R. Effects of excess free fatty acids on mechanical and metabolic function in normal and ischaemic myocardium in the swine. Circ Res 1978; 43: 652–61
   PubMed Web of Science ®Google Scholar
• Oliver M F. The influence of myocardial metabolism on ischemic damage. Circulation 1976; 54(Suppl. I)168–70
   Google Scholar
• Gudbjarnason S, Oskarsdottir G. Changes in fatty acid composition of cardiac lipids accompanying myocardial necrosis. Recent Adv Stud Card Struct Metab 1975; 6: 192–203
   Google Scholar
• Gudbjarnason S, Oskarsdottir G, Doell B, Hallgrimsson J. Myocardial membrane lipids in relation to cardiovascular disease. Adv Cardiol 1978; 25: 130–44
   PubMedGoogle Scholar
• Mead J F. Membrane lipid peroxidation and its prevention. J Am Oil Chem Soc 1980; 57: 393–7
   Web of Science ®Google Scholar