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Original Article

Phospholipid molecular species with eicosapentaenoic acid (20:5(n-3)) are less stable than species with arachidonic acid (20:4(n-6)) in isolated rat liver cells

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Pages 513-522 | Received 18 May 1994, Accepted 03 Apr 1995, Published online: 08 Jul 2009

References

  • Dyerberg J, Jorgensen K A. Marine oils and thrombogenesis. Prog Lipid Res 1982; 21: 255–69
  • Leaf A, Weber P C. Cardiovascular effects of n-3 fatty acids. N Engl J Med 1988; 318: 549–57
  • Harris W S. Fish oil and plasma lipid and lipoprotein metabolism in humans: a critical review. J Lipid Res 1989; 30: 785–807
  • Herold P M, Kinsella J E. Fish oil consumption and decreased risk of cardiovascular disease: a comparison of findings from animal and human feeding trials. Am J Clin Nutr 1986; 43: 566–98
  • Fischer S, Weber P C. Thromboxane A3 (TXA3) is formed in human platelets after dietary eicosapentaenoic acid (20:5w3). Biochem Biophys Res Commun 1983; 116: 1091–9
  • Fischer S, Weber P C. Prostaglandin I3 is formed in vivo in man after dietary eicosapentaenoic acid. Nature 1984; 307: 165–8
  • Dyerberg J, Bang H O. Haemostatic function and platelet polyunsaturated fatty acids in Eskimos. Lancet 1979; 2: 433–5
  • Needleman P, Raz A, Minkes M S, Ferrendeli J A, Sprecher H. Triene prostaglandins: prostacyclin and thromboxane biosynthesis and unique biological properties. Proc Natl Acad Sci USA 1979; 76: 944–8
  • Fischer S, Weber P C, Dyerberg J. The prostacyclin/thromboxane balance is favourable shifted in Greenland Eskimos. Prostaglandins 1986; 32: 235–41
  • White D A. The phospholipid composition of mammalian tissues. Form and function of phospholipids, Dawson Hawthorne Ansell. Elsevier. 1973; 441–78
  • Iritani N, Narita R. Changes of arachidonic and n-3 polyunsaturated fatty acids of phospholipid classes in liver, plasma and platelets during dietary fat manipulation. Biochim Biophys Acta 1984; 793: 441–7
  • Grønn M, Gørbitz C, Christensen E, Levorsen A, Ose L, Hagve T A, Christophersen B O. Dietary n-6 fatty acids inhibit the incorporation of dietary n-3 fatty acids in thrombocyte and serum phospholipids in humans: a controlled dietetic study. Scand J Clin Lab Invest 1991; 51: 255–63
  • Sundler R, Åkesson B, Nilsson å. Effect of different fatty acids on glycerolipid synthesis in isolated rat hepatocytes. J Biol Chem 1974; 249: 5102–7
  • Sundler R, Åkesson B. Regulation of phospholipid biosynthesis in isolated rat hepatocytes. Effect of different substrates. J Biol Chem 1975; 250: 3359–67
  • Åkesson B, Sundler R, Nilsson å. Biosynthesis of molecular species of glycerolipids in isolated rat hepatocytes. Lipids 1976; 1: 49–58
  • Kanoh H, Åkesson B. Phospholipid degradation in isolated rat hepatocytes. Metabolism of intracellularly formed dilinoleoyl-dipalmitoyl- and dimyristoylglycerophosphocholine. Biochim Biophys Acta 1977; 486: 511–23
  • Hagve T A, Christophersen B O. Linolenic acid desaturation and chain elongation and rapid turnover of phospholipid n-3 fatty acids in isolated rat liver cells. Biochim Biophys Acta 1983; 753: 339–49
  • Seglen P O. Preparation of rat liver cells. Exp Cell Res 1973; 82: 391–8
  • Nordby G, Berg T, Nilsson M, Norum K R. Secretion of lecithin: cholesterol acyltransferase from isolated rat hepatocytes. Biochim Biophys Acta 1976; 450: 69–77
  • Christiansen R, Borrebaek B, Bremer J. The effect of (-) carnitine on the metabolism of palmitate in liver cells isolated from fasted and refed rats. FEBS Lett 1976; 62: 313–17
  • Folch J, Lees M, Sloane-Stanley G H. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957; 226: 497–509
  • Grønn M, Christensen E, Hagve T A, Christophersen B O. Peroxisomal retroconversion of docosahexaenoic acid (22:6(n-3)) to eicosapen-taenoic acid (20:5(n-3)) studied in isolated rat liver cells. Biochim Biophys Acta 1991; 1081: 85–91
  • Arvidson G AE. Structural and metabolic heterogeneity of rat liver glycerophosphatides. Eur J Biochem 1968; 4: 478–86
  • Renkonen O. Mono- and dimethyl phosphatidates from different subtypes of choline and ethanolamine glycerophosphatides. Biochim Biophys Acta 1968; 152: 114–35
  • Holmsen H, Glomseth J A. Compartmentalisation. Acyl specificity and diacylglycerol recycling in fibroblast phospholipid metabolism stimulated with platelet-derived growth factor (PDGF). The 16th Scandinavian Symposium on Lipids, HardangerNorway, 1991, 285–90
  • Nakagawa Y, Waku K. Improved procedure for the separation of the molecular species of dimethyl-phosphatidate by high-performance liquid chromatography. J Chromatogr 1986; 381: 225–31
  • Patton G M, Fasulo J M, Robin S J. Separation of phospholipids and individual molecular species of phospholipids by high-performance liquid chromatography. J Lipid Res 1982; 23: 190–6
  • Lowry O H, Rosebrough N J, Farr A L, Randall R J. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265–75
  • Raclot T, Groscolas R. Individual fish-oil n-3 polyunsaturated fatty acid deposition and mobilization rates for adipose tissue of rats in a nutritional steady state. Am J Clin Nutr 1994; 60: 72–80

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