7
Views
3
CrossRef citations to date
0
Altmetric
Original Article

Interferon gamma production in whole peripheral blood culture in acute hepatitis B

, &
Pages 145-150 | Received 01 Feb 1995, Accepted 26 Oct 1995, Published online: 08 Jul 2009

References

  • Mieli-Vergani G, Vergani D, Portman B, White J, Lyon J, Murray-Lyon J, et al. Lymphocyte cytotoxicity to autologous hepatocytes in HBsAg-positive chronic liver disease. Gut 1982; 23: 1029–36
  • Mondelli M, Eddleston A. Lymphocyte cytotoxicity for autologous hepatocytes. Gut 1984; 25: 109–13
  • Arao M, Kakumu Sh, Tanara H, Yoshioka K. Interferon a- and g-positive mononuclear cells and HLA antigen expression in hepatocyte membrane in the liver in chronic type B and nod-nonB hepatitis. Gastroenterol Jpn 1989; 24: 255–61
  • Hu K.-Q, Yu C-H, Vierling JM. Up-regulation of intracellular adhesion molecule 1 transcription by hepatitis B virus X protein. Proc Natl Acad Sci USA 1992; 89: 11441–5
  • Dalton DK, Pitts-Meek SH, Keshav S, Figari IS, Bradley A, Stewart TA. Multiple defects of immune function in mice with disrupted interferon g-gene. Science 1993; 259: 1739–42
  • Ando K, Moriyama T, Guidotti LG, Wirth S, Scheiber RD, Schlicht HJ, et al. Mechanisms of class 1 restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J Exp Med 1993; 178: 1541–54
  • Hussain MJ, Mustafa A, Gallati H, Mowat AP, Mieli-Vergani G, Vergani D. Cellular expression of tumor necrosis factor-a and interferon-g in the liver biopsies of children with chronic liver disease. J Hepatol 1994; 21: 816–22
  • Kirchner H, Kleinicke C, Digel W. A whole blood technique for testing production of human interferon by leukocytes. J Immunol Meth 1982; 48: 213–19
  • De Groote D, Zangerle PF, Gevaert Y, Fassotte MF, Beguin Y, Noizat-Pienne F, et al. Direct stimulation of cytokines (IL-1B, TNFa, IL-6, IL-2, IFNg and CM-CSF) in whole blood. 1. Comparison with isolated PBMC stimulation. Cytokine 1992; 4: 239–48
  • Sandvig S, Laskay T, Anderson J, De Ley M, Anderson U. Gamma-interferon is produced by CD3+ and CD3– lymphocytes. Immunol Rev 1987; 97: 51–65
  • Wakita T, Kakumu S, Voshioka K, Ishikawa T, Ito V, Shhagawa T. Cellular immune responses of peripheral blood mononudears to HBV antigens during chronic and acute HBV infection. Digestion 1992; 52: 26–33
  • Gold KM, Weyland CM, Goronzy JF. Modulation of helper T1 cell function by prostaglaadios. Arthritis Rheum. 1994; 37: 925–33
  • Howard M O'Garra. Biological properties of IL-10. Immunol Today 1992; 13: 198–200
  • Ross C, Hanm MB, Schyberg T, Berg K. Autoantibodies to crude human leukocyte inter-feron (IFN), native human IFN, recombinant human IFN-alpha, recombinant buman IFN-alpha 2b and human IFN-gamma in healthy blood donors. Clin Exp Immunol 1990; 82: 56–7
  • Lau JY, Moms AG, Alexander GJ, Williams R. Interferon gamma receptor expression in chronic hepatitis B virus infection. J Hepatol 1992; 14: 294–9
  • Valente G, Omen L, Noveli F, Palestro G, Forni G, Garotta G. Distribution of IFNg receptors in human tissue. J Interfer Res 1991; 11: 209
  • Panonchi P, Carli MD, Manetti R, Simonelli C, Sampognaro S, Picchi M-P, et al. IL-4 and IFNa and -g exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human all clones. J Immunol 1992; 149: 2957–63
  • Alberti A. Pathobiology of hepatitis B virus infection and mechanism of action of interferon. Progress in Hepatology. European Association for the Study of the Liver, Paris 1993; 93
  • Foster GR, Goldin RD, Thomas HC, Stark GR. Expression of the hepatitis B virus polymerase is associated with failure to respond to interferon therapy. J Interfer Res 1991; 11: 124
  • Carreno V, Moreno A, Galiana F, Bartolome F. Alpha- and gamma-interferon versus alpha interferon alone in chronic hepatitis B. A randomized controlled study. J Hepatol 1993; 17: 321–5
  • Kakumu S, Ishikawa T, Wakita T, Yoshioka K, Takayanagi M, Tahara H, et al. Interferon-gamma production specific for hepatitis B virus antigen by intrahepatic T lymphocytes in patients with acute and chronic hepatitis B. Am J Gastroenterol 1994; 89: 92–6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.