Effect of bilirubin on erythrocyte shape and haemolysis, under hypotonic, aggregating or non-aggregating conditions, and correlation with cell age

References

• Kragh-Hansen U. Molecular aspects of ligand binding to serum albumin. Pharmacol Rev 1981; 33: 17–53
   PubMed Web of Science ®Google Scholar
• Brodersen R, Stern L. Deposition of bilirubin acid in the central nervous system—a hypothesis for the development of kernicterus. Acta Paediatr Scand 1990; 79: 12–19
   PubMedGoogle Scholar
• Wennberg R P, Hance A J. Experimental bilirubin encephalopathy: importance of total bilirubin, protein binding, and blood-brain barrier. Pediatr Res 1986; 20: 789–92
   PubMedGoogle Scholar
• Tiribelli C, Ostrow J D. New concepts in bilirubin chemistry, transport and metabolism. Report of the Second International Bilirubin Workshop, April 9–11, 1992, Trieste, Italy. Hepatology 1993; 17: 715–36
   PubMedGoogle Scholar
• Hansen T WR. Bilirubin entry into and clearance from rat brain during hypercabia and hyper-osmolality. Pediatr Res 1996; 39: 72–6
   PubMed Web of Science ®Google Scholar
• Leipe S. Bilirubin-induced cytomorphological changes in guinea-pig leucocytes. Biomed Biochim Acta 1983; 42: 503–10
   PubMedGoogle Scholar
• Knobloch E, Miler I. Interaction of bilirubin with human lymphocytes and granulocytes—the effect on bilirubin metabolism. Folia Microbiol 1986; 31: 387–93
   PubMedGoogle Scholar
• Notter M FD, Kendig J W. Differential sensitivity of neural cells to bilirubin toxicity. Exp Neurol 1986; 94: 670–82
   PubMed Web of Science ®Google Scholar
• Wennberg R P. The importance of free bilirubin acid salt in bilirubin uptake by erythrocytes and mitochondria. Pediatr Res 1988; 23: 443–7
   PubMedGoogle Scholar
• Amit Y, Cashore W, Schiff D. Studies of bilirubin toxicity at the synaptosome and cellular levels. Semin Perinatal 1992; 16: 186–90
   PubMedGoogle Scholar
• Amit Y, Boneh A. Bilirubin inhibits protein kinase C activity and protein kinase C-mediated phosphorylation of endogenous substrates in human skin fibroblasts. Clin Chim Acta 1993; 223: 103–11
   PubMed Web of Science ®Google Scholar
• Ochoa E LM, Wennberg R P, An Y, Tandon T, Takashima T, Nguyen T, Chui A. Interactions of bilirubin with isolated presynaptic nerve terminals: functional effects on the uptake and release of neurotransmitters. Cell Mol Neurobiol 1993; 13: 69–86
   PubMedGoogle Scholar
• Hayward D, Schiff D, Fedunec S, Chan G, Davis P J, Poznansky M J. Bilirubin diffusion through lipid membranes. Biochim Biophys Acta 1986; 8600: 149–53
   Google Scholar
• Ali S, Zakim D. The effects of bilirubin on the thermal properties of phosphatidylcholine bi-layers. Biophys J 1993; 65: 101–5
   PubMedGoogle Scholar
• Mustafa M G, King T E. Binding of bilirubin with lipid. A possible mechanism of its toxic reactions in mitochondria. J Biol Chem 1970; 245: 1084–9
   PubMed Web of Science ®Google Scholar
• Noy N, Leonard M, Zakim D. The kinetics of interactions of bilirubin with lipid bilayers and with serum albumin. Biophys Chem 1992; 42: 177–88
   PubMedGoogle Scholar
• Zucker S D, Goessling W, Zeidel M L, Gollan J L. Membrane lipid composition and vesicle size modulate bilirubin intermembrane transfer. J Biol Chem 1994; 269: 19262–70
   PubMedGoogle Scholar
• Eriksen E F, Danielsen H, Brodersen R. Bilirubin-liposome interaction. Binding of bilirubin dianion, protonization, and aggregation of bilirubin acid. J Biol Chem 1981; 256: 4269–74
   PubMedGoogle Scholar
• Vazquez J, Garcia-Calvo M, Valdivieso F, Mayor F, Mayor F, Jr. Interaction of bilirubin with the synaptosomal plasma membrane. J Biol Chem 1988; 263: 1255–65
   PubMed Web of Science ®Google Scholar
• Watson D. The absorption of bilirubin by erythrocytes. Clin Chim Acta 1962; 7: 733–4
   PubMed Web of Science ®Google Scholar
• Bratlid D. The effect of pH on bilirubin binding by human erythrocytes. Scand J Clin Lab Invest 1972; 29: 453–9
   PubMed Web of Science ®Google Scholar
• Bratlid D. Bilirubin binding by human erythrocytes. Scand J Clin Lab Invest 1972; 29: 91–7
   PubMed Web of Science ®Google Scholar
• Petrich C, Krieg W, Voss H V, Gobel U. Effects of bilirubin on red cell metabolism. J Clin Chem Clin Biochem 1977; 15: 77–80
   PubMedGoogle Scholar
• Sato H, Kashiwamata S. Interaction of bilirubin with human erythrocyte membranes. Biochem J 1983; 210: 489–96
   PubMedGoogle Scholar
• Silva R, Brites D, Correia L E. Interação da bilirrubina com a membrana eritrocitária. Resultados preliminares. Arq Port Cienc Biol 1989; 39: 34–9
   Google Scholar
• Brites D, Brito A, Silva R. Icterícia neonatal e toxicidade da bilirrubina. Novos aspectos. Rev Port Pediat 1993; 24: 325–30
   Google Scholar
• Hayer M, Piva M, Sieso V, Magnan de Bornier B. Experimental studies on unconjugated bilirubin binding by human erythrocytes. Clin Chim Acta 1989; 186: 345–50
   Google Scholar
• Chen L X, Lu J F, Wang K. The influence of bilirubin on fluidity and rotational correlation times of human erythrocyte membrane. Cell Biol Inter Rep 1992; 16: 567–73
   PubMedGoogle Scholar
• Sato H, Aono S, Semba R, Kashiwamata S. Interaction of bilirubin with human erythrocyte membranes. Bilirubin binding to neuraminidase-and phospholipase-treated membranes. Biochem J 1987; 248: 21–6
   PubMedGoogle Scholar
• Zucker S DJ, Storch J, Zeidel M L, Gollan J L. Mechanism of the spontaneous transfer of unconjugated bilirubin between small unilamellar phosphatidylcholine vesicles. Biochemistry 1992; 31: 3184–92
   PubMedGoogle Scholar
• Ostrow J D, Mukerjee P, Tiribelli C. Structure and binding of unconjugated bilirubin: relevance for physiological and pathophysiological function. J Lipid Res 1994; 35: 1715–37
   PubMed Web of Science ®Google Scholar
• Brodersen R, Stern L. Aggregation of bilirubin in injectates and incubation media: its significance in experimental studies of CNS toxicity. Neuropediatrics 1987; 18: 34–6
   PubMedGoogle Scholar
• Kaul R, Bajpai U K, Shipstone A C, Kaul A H, Murti C RK. Bilirubin-induced erythrocyte membrane cytotoxicity. Exp Mol Pathol 1981; 34: 290–8
   PubMed Web of Science ®Google Scholar
• Kirschner-Zilber I, Rabizadeh E, Shaklai N. The interaction of hemin and bilirubin with human red cell membrane. Biochim Biophys Acta 1982; 690: 20–30
   PubMed Web of Science ®Google Scholar
• Brito M A, Silva R M, Matos D C, Silva A T, Brites D T. Alterations of erythrocyte morphology and lipid composition by hyperbilirubinemia. Clin Chim Acta 1996; 249: 149–65
   PubMedGoogle Scholar
• Beutler E, West C. The removal of leukocytes and platelets from whole blood. J Lab Clin Med 1976; 88: 328–33
   PubMed Web of Science ®Google Scholar
• Vettore L, De Matteis M C, Zampini P. A new density gradient system for the separation of human red blood cells. Am J Hematol 1980; 8: 291–7
   PubMed Web of Science ®Google Scholar
• Carmagnol F, Sinet P-M, Rapin J, Jerome H. Glutathione-S-transferase of human red blood cells; assay values in normal subjects and in two pathological circumstances: hyperbilirubinemia and impaired renal function. Clin Chim Acta 1981; 117: 209–17
   PubMed Web of Science ®Google Scholar
• Brito M A. Quantifiçãgao da actividade enzimática da glutationa-S-transfeiase eritrocitária. Thesis for scientific and pedagogic evaluation. University of Lisbon, Lisbon 1990
   Google Scholar
• Yasuhara H, Tonooka M, Kamei K, Sakamoto K. Membrane effects of various drugs on isolated rat hepatocytes and erythrocvtes. Toxicol Appl Pharmacol 1985; 79: 453–60
   PubMedGoogle Scholar
• Jacobsen J, Wennberg R P. Determination of unbound bilirubin in the serum of newborns. Clin Chem 1974; 20: 783–9
   PubMed Web of Science ®Google Scholar
• Brodersen R, Cashore W, Wennberg R P, Ahlfors C E, Rasmussen L F, Shusterman D. Kinetics of bilirubin oxidation with peroxidase as applied to studies of bilirubin-albumin binding. Scand J Clin Lab Invest 1979; 39: 143–50
   PubMedGoogle Scholar
• Moreau-Clevede J, Pays M. Determination de la bilirubine érythrocytaire. Ann Biol Clin 1979; 37: 95–101
   PubMedGoogle Scholar
• Brites D, Silveira C, Pays M, Amaral J MV, Aparício O, Lobato M R. Bilirrubina eritrocitária no período neonatal precoce. Estudo do seu comportamento em recém-nascidos com e sem risco de iterfcia nuclear. Rev Port Pediat 1981; 12: 1–14
   Google Scholar
• Hsu R C, Kanofsky J R, Yachnin S. The formation of echinocytes by insertion of oxygenated sterol compounds into red cell membranes. Blood 1980; 56: 109–17
   PubMed Web of Science ®Google Scholar
• Todd J C, Sanford A H, Davidsohn I. Clinical diagnosis and management by laboratory methods, JB Henry. WB Saunders, Philadelphia 1979; 863–931
   Google Scholar
• Lovrien R, Tisel W, Pesheck P. Stoichiometry of compounds bound to human erythrocytes in relation to morphology. J Biol Chem 1975; 250: 3136–41
   PubMed Web of Science ®Google Scholar
• Fortes P AG. Ellory JC. Asymmetric membrane expansion and modification of active and passive cation permeability of human red cells by the fluorescent probe 1-anilino-8-naphthalene sulfonate. Biochim Biophys Acta 1975; 413: 65–78
   PubMedGoogle Scholar
• Eskelinen S, Saukko P. The hypotonic hemolysis and the protective action of lysophosphatidylcholine. Biorheology 1984; 21: 363–77
   PubMedGoogle Scholar
• Chi L, Wu W. Mechanism of hemolysis of red blood cell mediated by ethanol. Biochim Biophys Acta 1991; 1062: 46–50
   PubMedGoogle Scholar
• Sheetz M P, Singer S J. Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions. Proc Nat Acad Sci 1974; 71: 4457–61
   PubMed Web of Science ®Google Scholar
• Morimoto Y, Tanaka K, Lwakin Y, Tokuhiro S, Fukushima S, Takeuchi Y. Protective effects of some neutral amino acids against hypotonic hemolysis. Biol Pharm Bull 1995; 10: 1417–22
   Google Scholar
• Lange L G, Van Meer G, Op Den Kamp J AF, Van Deenen L LM. Hemolysis of rat erythrocytes by replacement of the natural phosphatidylcholine by various phosphatidylcholines. Eur J Bio-chem 1980; 110: 115–21
   Google Scholar
• Fujii T, Sato T, Tamura A, Wakatsuki M, Kanaho Y. Shape changes of human erythrocytes induced by various amphipathic drugs acting on the membrane of the intact cells. Biochem Pharmacol 1979; 28: 613–20
   PubMed Web of Science ®Google Scholar
• Nagaoka S, Cowger M L. Interaction of bilirubin with lipids studied by fluorescence quenching method. J Biol Chem 1978; 253: 2005–11
   PubMedGoogle Scholar
• Glushko V, Thaler M, Ross M. The fluorescence of bilirubin upon interaction with human erythrocyte ghosts. Biochim Biophys Acta 1982; 719: 65–73
   PubMedGoogle Scholar
• Marwaha N, Sarode R, Marwaha R K, Sharma S, Yachha S, Narang A. Bilirubin crystals in peripheral blood smears from neonates with unconjugated hyperbilirubinaemia. Med Lab Sci 1990; 47: 278–81
   PubMedGoogle Scholar
• Greenwalt T J, Dumaswala U J. Effect of red cell age on vesiculation in vitro. Br J Haematol 1988; 68: 465–7
   PubMedGoogle Scholar
• Bartosz G. Erythrocyte ageing: physical and chemical membrane changes. Gerontology 1991; 37: 33–67
   PubMed Web of Science ®Google Scholar
• Sutera S P, Gardner R A, Boylan C W, Carroll G L, Chang K C, Marvel J S. Age-related changes in deformability of human erythrocvtes. Blood 1985; 65: 275–82
   PubMedGoogle Scholar
• Shukla S D, Hanahan D J. Membrane alterations in cellular ageing: susceptibility of phospholipids in density (age)-separated human erythrocytes to phospholipase A2. Arch Biochem Biophys 1982; 214: 335–41
   PubMedGoogle Scholar
• Danon D, Marikovsky Y. The ageing of the red blood cell. A multifactor process. Blood Cells 1988; 14: 7–15
   PubMedGoogle Scholar
• Seaman G VF, Knox R J, Nordt F J, Regan D H. Red cell aging. I Surface charge density and sialic acid content of density-fractionated human erythrocytes. Blood 1977; 50: 1001–11
   PubMed Web of Science ®Google Scholar
• Brodersen R. Physical chemistry of bilirubin: binding to macromolecules and membranes. Bilirubin, K PM Heirwegh, S B Brown. CRC Press., Boca Raton, Florida 1982; 75–123
   Google Scholar
• Tayyab S, Ali M K. Binding of bilirubin to erythrocytes from different mammalian species. Comp Biochem Physiol 1995; 111 A: 507–9
   Google Scholar