1,714
Views
37
CrossRef citations to date
0
Altmetric
Inflammitary Bowel Disease

Activation of REG family proteins in colitis

, , , , , , & show all
Pages 1316-1323 | Received 22 Dec 2010, Accepted 04 Jul 2011, Published online: 13 Oct 2011

References

  • Yonemura Y, Takashima T, Miwa K, Miyazaki I, Yamamoto H, Okamoto H. Amelioration of diabetes mellitus in partially depancreatized rats by poly(ADP-ribose) synthetase inhibitors. Evidence of islet B-cell regeneration. Diabetes 1984;33:401–4.
  • Zhang YW, Ding LS, Lai MD. Reg gene family and human diseases. World J Gastroenterol 2003;9:2635–41.
  • Fukui H, Kinoshita Y, Maekawa T, Okada A, Waki S, Hassan S, Regenerating gene protein may mediate gastric mucosal proliferation induced by hypergastrinemia in rats. Gastroenterology 1998;115:1483–93.
  • Watanabe T, Yonekura H, Terazono K, Yamamoto H, Okamoto H. Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene. J Biol Chem 1990;265:7432–9.
  • Bernard-Perrone FR, Renaud WP, Guy-Crotte OM, Bernard P, Figarella CG, Okamoto H, Expression of REG protein during cell growth and differentiation of two human colon carcinoma cell lines. J Histochem Cytochem 1999;47:863–70.
  • Lawrance IC, Fiocchi C, Chakravarti S. Ulcerative colitis and Crohn's disease: distinctive gene expression profiles and novel susceptibility candidate genes. Hum Mol Genet 2001;10:445–56.
  • Wu F, Dassopoulos T, Cope L, Maitra A, Brant SR, Harris ML, Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis. Inflamm Bowel Dis 2007;13:807–21.
  • Dieckgraefe BK, Crimmins DL, Landt V, Houchen C, Anant S, Porche-Sorbet R, Expression of the regenerating gene family in inflammatory bowel disease mucosa: Reg Ialpha upregulation, processing, and antiapoptotic activity. J Investig Med 2002;50:421–34.
  • Csillag C, Nielsen OH, Vainer B, Olsen J, Dieckgraefe BK, Hendel J, Expression of the genes dual oxidase 2, lipocalin 2 and regenerating islet-derived 1 alpha in Crohn's disease. Scand J Gastroenterol 2007;42:454–63.
  • Sekikawa A, Fukui H, Fujii S, Nanakin A, Kanda N, Uenoyama Y, Possible role of REG Ialpha protein in ulcerative colitis and colitic cancer. Gut 2005;54:1437–44.
  • Tanaka H, Fukui H, Fujii S, Sekikawa A, Yamagishi H, Ichikawa K, Immunohistochemical Analysis of REG IÎ ± Expression in Ulcerative Colitis-Associated Neoplastic Lesions. Digestion 2011;83:204–9.
  • Sekikawa A, Fukui H, Suzuki K, Karibe T, Fujii S, Ichikawa K, Involvement of the IL-22/REG I[alpha] axis in ulcerative colitis. Lab Invest 2010;90:496–505.
  • Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004;5:R80.
  • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004;3: Article3.
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402–8.
  • Kamarainen M, Heiskala K, Knuutila S, Heiskala M, Winqvist O, Andersson LC. RELP, a novel human REG-like protein with up-regulated expression in inflammatory and metaplastic gastrointestinal mucosa. Am J Pathol 2003;163:11–20.
  • Heiskala K, Giles-Komar J, Heiskala M, Andersson LC. High expression of RELP (Reg IV) in neoplastic goblet cells of appendiceal mucinous cystadenoma and pseudomyxoma peritonei. Virchows Arch 2006;448:295–300.
  • Spiller R. Serotonin and GI clinical disorders. Neuropharmacology 2008;55:1072–80.
  • Cash HL, Whitham CV, Behrendt CL, Hooper LV. Symbiotic Bacteria Direct Expression of an Intestinal Bactericidal Lectin. Science 2006;313:1126–30.