Food intake and meal pattern in IAPP knockout mice with and without infusion of exogenous IAPP

References

• Lukinius A, Wilander E, Westermark GT, Engström U, Westermark P. Co-localization of islet amyloid polypeptide and insulin and the B cell secretory granules of the human pancreatic islets. Diabetologia 1989;32:240–4.
   PubMed Web of Science ®Google Scholar
• Westermark P, Wernstedt C, Wiklander E, Hayden DW, O´Brien TD, Johnson KH. Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells. Proc Natl Acad Sci USA 1987;84:3881–5.
   PubMed Web of Science ®Google Scholar
• Beaumont K, Kenney MA, Young AA, Rank TJ. High affinity amylin binding sites in rat brain. Mol Pharmacol 1993;44:493–7.
   PubMed Web of Science ®Google Scholar
• Bhogal R, Smith DM, Bloom SR. Investigation and characterization of binding sites for islet amyloid polypeptide in rat membranes. Endocrinology 1992;130:906–13.
   PubMedGoogle Scholar
• Bhogal R, Smith DM, Purkiss P, Bloom SR. Molecular identification of binding sites for calcitonin gene-related peptide (CGRP) and islet amyloid polypeptide (IAPP) in mammalian lung: species variation and binding of truncated CGRP and IAPP. Endocrinology 1993;133:2351–61.
   PubMedGoogle Scholar
• Sexton PM, Paxinos G, Kenney MA, Wookey PJ, Beaumont K. In vitro autoradiographic localization of amylin binding sites in rat brain. Neuroscience 1994;62:553–67.
   PubMed Web of Science ®Google Scholar
• Arnelo U, Permert J, Adrian TE, Larsson J, Westermark P, Reidelberger RD. Chronic infusion of islet amyloid polypeptide causes anorexia in rats. Am J Physiol Regul Integr Comp Physiol 1996;271:R1654–9.
   Google Scholar
• Arnelo U, Reidelberger RD, Adrian TE, Larsson J, Permert J. Suffiency of postprandial plasma levels of islet amyloid polypeptide for suppression of feeding in rats. Am J Physiol Regul Integr Comp Physiol 1998;275:R1537–42.
   Google Scholar
• Clementi G, Caruso A, Cutuli VM, de Bernardis E, Prato A, Amico-Roxas M. Amylin given by central or peripheral routes decreases gastric emptying and intestinal transit in the rat. Experientia 1996;52:677–9.
   PubMedGoogle Scholar
• Isaksson B, Wang F, Permert J, Olsson M, Fruin B, Herrington MK, Chronically administered islet amyloid polypeptide in rats serves as an adiposity inhibitor and regulates energy homeostasis. Pancreatology 2005;5:29–36.
   PubMedGoogle Scholar
• Reidelberger RD, Arnelo U, Granqvist L, Permert J. Comparative effects of amylin and cholecystokinin on food intake and gastric emptying in rats. Am J Physiol Regul Integr Comp Physiol 2001;280:R605–11.
   PubMed Web of Science ®Google Scholar
• Rushing PA, Hagan MM, Seeley RJ, Lutz TA, Woods SC. Amylin: a novel action in the brain to reduce body weight. Endocrinology 2000;142:850–3.
   Google Scholar
• Rushing PA, Hagan MM, Seeley RJ, Lutz TA, D´Alessio DA, Air EL, Inhibition of central amylin signaling increases food intake and body adiposity in rats. Endocrinology 2001;142:5035–8.
   PubMedGoogle Scholar
• Young AA, Gedulin BR, Rink TJ. Dose-response for the slowing of gastric emptying in a rodent model by glucagon-like-peptide (7-36)NH2, amylin, cholecystokinin, and other possible regulators of nutrient uptake. Metabolism 1996;45:1–3.
   PubMed Web of Science ®Google Scholar
• Aronne L, Fujioka K, Aroda V, Chen K, Halseth A, Kesty NC, Progressive reduction in body weight after treatment with the amylin analog pramlintide in obese subjects: A phase 2, randomized, placebo-controlled, dose-escalation study. J Clin Endocrinol Metab 2007;92:2977–83.
   PubMed Web of Science ®Google Scholar
• Chapman I, Parker B, Doran S, Feinle-Bisset C, Wishart J, Lush CW, Low-dose pramlintide reduced food intake and meal duration in healthy, normal-weight subjects. Obesity 2007;15:1179–86.
   PubMedGoogle Scholar
• Smith SR, Blundell JE, Burns C, Ellero C, Schroeder BE, Kesty NC, Pramlintide treatment reduces 24-h caloric intake and meal sizes and improves control of eating in obese subjects: a 6-wk translational research study. Am J Physiol Endocrinol Metab 2007;293:E620–7.
   PubMed Web of Science ®Google Scholar
• Edelman SV. Optimizing diabetes treatment using an amylin analogue. Diabetes Educ 2008;34(Suppl 1):4S–10S.
   Google Scholar
• Hollander PA, Levy P, Fineman MS, Maggs DG, Shen LZ, Strobel SA, Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trial. Diabetes Care 2003;26:784–90.
   PubMed Web of Science ®Google Scholar
• Muff R, Buhlmann N, Fischer JA, Born W. An amylin receptor is revealed following cotransfection of a calcitonin receptor with receptor activity modifying proteins-1 or -3. Endocrinology 1999;140:2924–7.
   PubMed Web of Science ®Google Scholar
• Poyner DR, Sexton PM, Marshall I, Smith DM, Quirion R, Born W, International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacol Rev 2002;54:233–46.
   PubMed Web of Science ®Google Scholar
• Zumpe ET, Tilakaratne N, Fraser NJ, Christopoulos G, Foord SM, Sexton PM. Multiple ramp domains required for generation of amylin receptor phenotype from the calcitonin receptor gene product. Biochem Biophys Res Commun 2000;267:368–72.
   PubMed Web of Science ®Google Scholar
• Reidelberger RD, Haver AC, Arnelo U, Smith DD, Schaffert CS, Permert J. Amylin receptor blockade stimulates food intake in rats. Am J Physiol Regul Integr Comp Physiol 2004;287:R568–74.
   Google Scholar
• Dacquin R, Davey RA, Laplace C, Levasseur R, Morris HA, Goldring SR, Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo. J Cell Biol 2004;164:509–14.
   PubMedGoogle Scholar
• Gebre-Medhin S, Mulder H, Pekny M, Westermark G, Törnell J, Westermark P, Increased insulin secretion and glucose tolerance in mice lacking islet amyloid polypeptide (amylin). Biochem Biophys Res Commun 1998;250:271–7.
   PubMed Web of Science ®Google Scholar
• Lutz TA. Pancreatic amylin as a centrally acting satiating hormone. Curr Drug Targets 2005;6:181–9.
   PubMed Web of Science ®Google Scholar
• Olsson M, Herrington MK, Reidelberger RD, Permert J, Arnelo U. Comparison of the effects of chronic central administration and chronic peripheral administration of islet amyloid polypeptide on food intake and meal pattern in the rat. Peptides 2007;28:1416–23.
   PubMedGoogle Scholar
• Arnelo U, Herrington MK, Theodorsson E, Adrian TE, Reidelberger R, Larsson J, Effects of long-term infusion of anorexic concentrations of islet amyloid polypeptide on neurotransmitters and neuropeptides in rat brain. Brain Res 2000;887:391–8.
   PubMedGoogle Scholar
• Kirk RE. Experimental design: Procedures for the behavioral sciences. Pacific Grove, USA: Brooks/Cole Publishing Company; 1995.
   Google Scholar
• Littell RC, Milliken GA, Stroup WW, Wolfinger RD, Schabenberger O. SAS System for Mixed Models. 2nd ed. Cary, NC: SAS Institute, Inc; 2006.
   Google Scholar
• Turek VF, Trevaskis JL, Levin BE, Dunn-Meynell AA, Irani B, Gu G, Mechanisms of amylin/leptin synergy in rodent models. Endocrinology 2010;151:143–52.
   PubMed Web of Science ®Google Scholar
• Mollet A, Meier S, Grabler V, Gilg S, Scharrer E, Lutz TA. Endogenous amylin contributes to the anorectic effects of cholecystokinin and bombesin. Peptides 2003;24:91–8.
   PubMedGoogle Scholar
• Lutz TA, Geary N, Szabady MM, Del Prete E, Scharrer E. Amylin decreases meal size in rats. Physiol Behav 1995;58:1197–202.
   PubMedGoogle Scholar
• Petersen S, McCarthy JC. Correlated changes in feeding behavior on selection for large and small body size in mice. Behav Genet 1981;11:57–64.
   PubMedGoogle Scholar
• Strohmayer AJ, Smith GP. A sex difference in the effect of CCK-8 on food and water intake in obese (ob/ob) and lean (+/+) mice. Peptides 1987;8:845–8.
   PubMedGoogle Scholar