Influence of preformed donor-specific antibodies and C4d on early liver allograft function

References

• Andres GA, Ansell ID, Halgrimson CG, Hsu KC, Porter KA, Starzl TE, et al. Immunopathological studies of orthotopic human liver allografts. Lancet 1972;1:275–80.
   PubMed Web of Science ®Google Scholar
• Starzl TE, Ishikawa M, Putnam CW, Porter KA, Picache R, Husberg BS, et al. Progress in and deterrents to orthotopic liver transplantation, with special reference to survival, resistance to hyperacute rejection, and biliary duct reconstruction. Transplant Proc 1974;6:129–39.
   PubMed Web of Science ®Google Scholar
• Rowshani AT, Bemelman FJ, Lardy NM, Ten Berge IJ. Humoral immunity in renal transplantation: clinical significance and therapeutic approach. Clin Transplant 2008;22:689–99.
   PubMed Web of Science ®Google Scholar
• Masson E, Stern M, Chabod J, Thevenin C, Gonin F, Rebibou JM, et al. Hyperacute rejection after lung transplantation caused by undetected low-titer anti-HLA antibodies. J Heart Lung Transplant 2007;26:642–5.
   PubMed Web of Science ®Google Scholar
• Demetris AJ, Jaffe R, Tzakis A, Ramsey G, Todo S, Belle S, et al. Antibody-mediated rejection of human orthotopic liver allografts. A study of liver transplantation across ABO blood group barriers. Am J Pathol 1988;132:489–502.
   PubMed Web of Science ®Google Scholar
• Demetris AJ, Jaffe R, Tzakis A, Ramsey G, Todo S, Belle S, et al. Antibody mediated rejection of human liver allografts: transplantation across ABO blood group barriers. Transplant Proc 1989;21:2217–20.
   PubMed Web of Science ®Google Scholar
• Demetris AJ, Nakamura K, Yagihashi A, Iwaki Y, Takaya S, Hartman GG, et al. A clinicopathological study of human liver allograft recipients harboring preformed IgG lymphocytotoxic antibodies. Hepatology 1992;16:671–81.
   PubMed Web of Science ®Google Scholar
• Terasaki PI. Humoral theory of transplantation. Am J Transplant 2003;3:665–73.
   PubMed Web of Science ®Google Scholar
• Colvin RB, Smith RN. Antibody-mediated organ-allograft rejection. Nat Rev Immunol 2005;5:807–17.
   PubMed Web of Science ®Google Scholar
• Colvin RB. Pathology of chronic humoral rejection. Contrib Nephrol 2009;162:75–86.
   PubMed Web of Science ®Google Scholar
• Colvin RB. Antibody-mediated renal allograft rejection: diagnosis and pathogenesis. J Am Soc Nephrol 2007;18:1046–56.
   PubMed Web of Science ®Google Scholar
• Rostron A, Carter V, Mutunga M, Cavanagh G, O'Suilleabhain C, Burt A, et al. A case of acute humoral rejection in liver transplantation: successful treatment with plasmapheresis and mycophenolate mofetil. Transpl Int 2005;18:1298–301.
   PubMed Web of Science ®Google Scholar
• Watson R, Kozlowski T, Nickeleit V, Woosley JT, Schmitz JL, Zacks SL, et al. Isolated donor specific alloantibody-mediated rejection after ABO compatible liver transplantation. Am J Transplant 2006;6:3022–9.
   PubMed Web of Science ®Google Scholar
• Hadaya K, Ferrari-Lacraz S, Giostra E, Majno P, Moll S, Rubbia-Brandt L, et al. Humoral and cellular rejection after combined liver-kidney transplantation in low immunologic risk recipients. Transpl Int 2009;22:242–6.
   PubMed Web of Science ®Google Scholar
• Wilson CH, Agarwal K, Carter V, Burt AD, Hubscher S, Talbot D, et al. Late humoral rejection in a compliant ABO-compatible liver transplant recipient. Transplantation 2006;82:988–9.
   PubMed Web of Science ®Google Scholar
• Ratner LE, Phelan D, Brunt EM, Mohanakumar T, Hanto DW. Probable antibody-mediated failure of two sequential ABO-compatible hepatic allografts in a single recipient. Transplantation 1993;55:814–19.
   PubMed Web of Science ®Google Scholar
• Troxell ML, Weintraub LA, Higgins JP, Kambham N. Comparison of C4d immunostaining methods in renal allograft biopsies. Clin J Am Soc Nephrol 2006;1:583–91.
   PubMed Web of Science ®Google Scholar
• Troxell ML, Higgins JP, Kambham N. Evaluation of C4d staining in liver and small intestine allografts. Arch Pathol Lab Med 2006;130:1489–96.
   PubMed Web of Science ®Google Scholar
• Haas M, Ratner LE, Montgomery RA. C4d staining of perioperative renal transplant biopsies. Transplantation 2002;74:711–17.
   PubMed Web of Science ®Google Scholar
• Haas M, Mirocha J. Early ultrastructural changes in renal allografts: correlation with antibody-mediated rejection and transplant glomerulopathy. Am J Transplant 2011;11:2123–31.
   PubMed Web of Science ®Google Scholar
• Silva MA, Mirza DF, Murphy N, Richards DA, Reynolds GM, Wigmore SJ, et al. Intrahepatic complement activation, sinusoidal endothelial injury, and lactic acidosis are associated with initial poor function of the liver after transplantation. Transplantation 2008;85:718–25.
   PubMed Web of Science ®Google Scholar
• Neil DA, Hubscher SG. Current views on rejection pathology in liver transplantation. Transpl Int 2010;23:971–83.
   PubMed Web of Science ®Google Scholar
• Bellamy CO. Complement C4d immunohistochemistry in the assessment of liver allograft biopsy samples: applications and pitfalls. Liver Transpl 2011;17:747–50.
   PubMed Web of Science ®Google Scholar
• Bellamy CO, Herriot MM, Harrison DJ, Bathgate AJ. C4d immunopositivity is uncommon in ABO-compatible liver allografts, but correlates partially with lymphocytotoxic antibody status. Histopathology 2007;50:739–49.
   PubMed Web of Science ®Google Scholar
• Taner T, Gandhi MJ, Sanderson SO, Poterucha CR, De Goey SR, Stegall MD, et al. Prevalence, course and impact of HLA donor-specific antibodies in liver transplantation in the first year. Am J Transplant 2012;12:1504–10.
   PubMed Web of Science ®Google Scholar
• Hathaway M, Gunson BK, Keogh AC, Briggs D, McMaster P, Neuberger JM. A positive crossmatch in liver transplantation–no effect or inappropriate analysis? A prospective study. Transplantation 1997;64:54–9.
   PubMed Web of Science ®Google Scholar
• Lobo PI, Spencer C, Douglas MT, Stevenson WC, Pruett TL. The lack of long-term detrimental effects on liver allografts caused by donor-specific anti-HLA antibodies. Transplantation 1993;55:1063–6.
   PubMed Web of Science ®Google Scholar
• Neumann UP, Lang M, Moldenhauer A, Langrehr JM, Glanemann M, Kahl A, et al. Significance of a T-lymphocytotoxic crossmatch in liver and combined liver-kidney transplantation. Transplantation 2001;71:1163–8.
   PubMed Web of Science ®Google Scholar
• Takaya S, Bronsther O, Iwaki Y, Nakamura K, Abu-Elmagd K, Yagihashi A, et al. The adverse impact on liver transplantation of using positive cytotoxic crossmatch donors. Transplantation 1992;53:400–6.
   PubMed Web of Science ®Google Scholar
• Castillo-Rama M, Castro MJ, Bernardo I, Meneu-Diaz JC, Elola-Olaso AM, Calleja-Antolin SM, et al. Preformed antibodies detected by cytotoxic assay or multibead array decrease liver allograft survival: role of human leukocyte antigen compatibility. Liver Transpl 2008;14:554–62.
   PubMed Web of Science ®Google Scholar
• Kozlowski T, Rubinas T, Nickeleit V, Woosley J, Schmitz J, Collins D, et al. Liver allograft antibody-mediated rejection with demonstration of sinusoidal C4d staining and circulating donor-specific antibodies. Liver Transpl 2011;17:357–68.
   PubMed Web of Science ®Google Scholar
• O'Leary JG, Kaneku H, Jennings LW, Banuelos N, Susskind BM, Terasaki PI, et al. Preformed class II donor-specific antibodies are associated with an increased risk of early rejection after liver transplantation. Liver Transpl 2013;19:973–80.
   PubMed Web of Science ®Google Scholar
• Batts KP, Moore SB, Perkins JD, Wiesner RH, Grambsch PM, Krom RA. Influence of positive lymphocyte crossmatch and HLA mismatching on vanishing bile duct syndrome in human liver allografts. Transplantation 1988;45:376–9.
   PubMed Web of Science ®Google Scholar
• Kozlowski T, Andreoni K, Schmitz J, Hayashi PH, Nickeleit V. Sinusoidal C4d deposits in liver allografts indicate an antibody-mediated response: diagnostic considerations in the evaluation of liver allografts. Liver Transpl 2012;18:641–58.
   PubMed Web of Science ®Google Scholar