5
Views
25
CrossRef citations to date
0
Altmetric
Original Article

Investigations on the Effect of an Oral Contraceptive and its Components on Liver Function, Serum Proteins, Copper, Coeruloplasmin and γ -Glutamyl Peptidase in Postmenopausal Women

, , , , &
Pages 273-284 | Received 01 Feb 1968, Accepted 02 Mar 1968, Published online: 25 Feb 2010

REFERENCES

  • Adlercreutz, E. (1959) Kliniska symptom på endokrina rubbningar vid leverskador. Nord. Med. 61, 427–430.
  • Adlercreutz, H. (1964) Steroidbetingad ikterus. Nord. Med. 72, 1004–1005.
  • Adlercreutz, H. & Ikonen, E. (1964) Oral contraceptives and liver damage. Brit. med. J. II, 1133.
  • Adlercreutz, H., Svanborg, A. & Ånberg, Å. (1967) Recurrent jaundice in pregnancy. II. A study of the estrogens and their conjugation in late pregnancy. Amer. J. Med. 42, 341–347.
  • Aronsen, K. F., Nosslin, B. & Pihl, B. (1967) The value of glutamyl transpeptidase in detection of liver metastases in patients with abdominal cancer. Scand. J. clin. Lab. Invest. 19, Suppl. 100, 107.
  • Bearn, A. G., Kunkel, H. G. & Slater, R. J. (1956) The problem of chronic liver disease in young women. Amer. J. Med. 21, 3–15.
  • Bessey, D. A., Lowry, O. H. & Brock, M. J. (1946) A method for the rapid determination of alkaline phosphatase with five cubic millimeters of serum. J. biol. Chem. 164, 321–329.
  • Boake, W. C. (1967) Effects of natural and synthetic oestrogens and progestogens on hepatic function. Acta endocr. (Kbh.) Suppl. 119, 169.
  • BONGIOVANNI, A. M. & EISENMENGER, W. J. (1951) Adrenal cortical metabolism in chronic liver disease. J. clin. Endocrin. 11, 152–172.
  • Borglin, N. E. (1965) Oral contraceptives and liver damage. Brit. med. J. II, 1289–1290.
  • Carruthers, M. E., Hobbs, C. B. & Warren, R. L. (1966) Raised serum copper and caeruloplasmin levels in subjects taking oral contraceptives. J. clin. Path. 19, 498–500.
  • Drill, V. A. (1966) Oral Contraceptives, McGraw-Hill, New York.
  • Eisalo, A., Järvinen, P. A. & Luukkainen, T. (1964) Hepatic impairment during the intake of contraceptive pills: clinical trial with postmenopausal women. Brit. med. J. II, 426–427.
  • Eisalo, A., Järvinen, P. A. & Luukkainen, T. (1965) Liver-function tests during intake of contraceptive tablets in pre-menopausal women. Brit. med. J. I, 1416–1417.
  • Eisalo, A., Luukkainen, T. & Jårvinen, P. A. (1966) Importance of the type of the progestogen in oral contraceptives. Acta obstet. gynec. scand. 45, Suppl. 9, 47–51.
  • Elsner, P. & Hornykiewicz, O. (1954) Die Beeinflussbarkeit der p-Polyphenoloxydaseaktivität des menschlichen Blutserums durch Sexualhormone. Arch. Gynäk. 185, 251–257.
  • Fawcett, J. W. & Pedersen, D. L. (1964) Oral contraceptives and liver damage. Brit. med. J. II, 755.
  • Gallagher, T. F., Jr., Mueller, M. N. & Kappas, A. (1966) Estrogen pharmacology IV. Studies on the structural basis for estrogen-induced impairment of liver function. Medicine 45, 471–479.
  • Gault, M. H., Stein, J. & Aronoff, A. (1966) Serum ceruloplasmin in hepatobiliary and other disorders: significance of abnormal values. Gastroenterology 50, 8–18.
  • German, J. L. & Bearn, A. G. (1961) Effect of estrogens on copper metabolism in liver disease. J. clin. Invest. 40, 445–453.
  • Holmberg, C. G. & Laurell, C. B. (1948) Investigation in serum copper. II. Isolation of the copper containing protein, and a description of some of its properties. Acta chem. scand. 2, 550–556.
  • Ikonen, E. (1964) Jaundice in late pregnancy. Acta obstet. gynec. scand. 43, Suppl. 5.
  • Kappas, A. (1967) Estrogens and the liver. Gastroenterology. 52, 113–116.
  • Karmen, A. (1955) A note on the spectrophotometric assay of glutamic-oxalacetic transaminase in human blood serum. J. clin. Invest. 34, 131–133.
  • Kingsley, G. R., Getchell, G. & Schaffert, R. R. (1953) p. 11 in Standard Methods of Clinical Chemistry, vol. I, Academic Press, New York.
  • Kleiner, G. J., Kresch, L. & Arias, I. M. (1965) Studies of hepatic excretory function. II. The effect of norethynodrel and mestranol on bromsulfalein sodium metabolism in women of childbearing age. New Engl. J. Med. 273, 420–423.
  • Kreek, M. J., Peterson, R. E., Sleisenger, M. H. & Jeffries, G. H. (1967a) Influence of ethinyl estradiolinduced cholestasis in bile flow and biliary excretion of estradiol and bromsulfophthalein by the rat. J. clin. Invest. 46, 1080.
  • Kreek, M. J., Sleisenger, M. H. & Jeffries, G. H. (1967b) Recurrent cholestatic jaundice of pregnancy with demonstrated estrogen sensitivity. Amer. J. Med. 43, 795–803.
  • Larsson-Cohn, U. & Stenram, U. (1967) Liver ultra-structure and function in icteric and non-icteric women using oral contraceptive agents. Acta med. scand. 181, 257–264.
  • Levonen, E. (1967) Partially automated determination of transaminases and lactic dehydrogenase using automatic spectrophotometer. Scand. J. clin. Lab. Invest. 19, Suppl. 100, 142.
  • Mueller, M. N. & Kappas, A. (1964) Estrogen pharmacology. I. The influence of estradiol and estriol on hepatic disposal of sulfobromophthalein (BSP) in man. J. clin. Invest. 43, 1905-1914.
  • Ockner, R. K. & Davidson, C. S. (1967) Hepatic effects of oral contraceptives. New Engl. J. Med. 276, 331–334.
  • Orellana-Alcade, J. M. & Dominguez, J. P. (1966) Jaundice and oral contraceptive drugs. Lancet II, 1278–1280.
  • Orlowski, M. & Szewczuk, A. (1961) Colorimetric determination of γ-glutamyl transpeptidase activity in human serum and tissues with synthetic substrates. Acta biochim. pol. 8, 189–200.
  • Owen, J. A. (1958) p. 237 in Advances in Clinical Chemistry, vol. I, Academic Press, New York.
  • Palva, I. P. & Mustala, O. O. (1964) Oral contraceptives and liver damage. Brit. med. J. II, 688–689.
  • Pilgeram, L. O. & Pickart, L. R. (1963) Depression of plasma albumin by steroid therapy. Proc. Soc. exp. Biol. (N.Y.) 112, 758–760.
  • Ravin, H. A. (1961) An improved colorimetric enzymatic assay of ceruloplasmin. J. lab. clin. Med. 58, 161–168.
  • Robertson, G. S. (1967) Serum protein and cholinesterase changes in association with contraceptive pills. Lancet I, 232–235.
  • Russ, E. M. & Raymunt, J. (1956) Influence of estrogens on total serum copper and caeruloplasmin. Proc. Soc. exp. Biol. (N.Y.) 92, 465–466.
  • Schaffner, F. (1966) The effects of oral contraceptives on the liver. J. Amer. med. Ass. 198, 1019–1021.
  • Seligson, D. & Marino, J. (1958) p. 186 in Standard Methods of Clinical Chemistry, vol. II, Academic Press, New York.
  • Sotaniemi, E., Kreus, K. E. & Scheinin, T. M. (1964) Oral contraceptives and liver damage. Brit. med. J. II, 1264.
  • Stoll, B. A., Andrews, J. T. & Motteram, R. (1966) Liver damage from oral contraceptives. Brit. med. J. I, 960–961.
  • Wroblewski, F. & LaDue, J. S. (1955) Serum glutamic oxalacetic transaminase activity as an index of liver cell injury: a preliminary report. Ann. int. Med. 43, 345–360.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.