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Scandinavian Journal of Gastroenterology Volume 6, 1971 - Issue 5
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Original Article

Pig-Liver Perfusion

Extracorporeal Pig-Liver Perfusion in a Patient with Acute Hepatic Failure

M. Lempinen The Second and Third Depts. of Surgery, University Central Hospital, Helsinki, and the Second Dept. of Pathology, University of Helsinki, Helsinki, Finland
,
Y. Collan The Second and Third Depts. of Surgery, University Central Hospital, Helsinki, and the Second Dept. of Pathology, University of Helsinki, Helsinki, Finland
,
A. Sivula The Second and Third Depts. of Surgery, University Central Hospital, Helsinki, and the Second Dept. of Pathology, University of Helsinki, Helsinki, Finland
,
E. Merikallio The Second and Third Depts. of Surgery, University Central Hospital, Helsinki, and the Second Dept. of Pathology, University of Helsinki, Helsinki, Finland
,
K. Salmenkivi The Second and Third Depts. of Surgery, University Central Hospital, Helsinki, and the Second Dept. of Pathology, University of Helsinki, Helsinki, Finland
,
M. Paloheimo The Second and Third Depts. of Surgery, University Central Hospital, Helsinki, and the Second Dept. of Pathology, University of Helsinki, Helsinki, Finland
,
M. T. Turunen The Second and Third Depts. of Surgery, University Central Hospital, Helsinki, and the Second Dept. of Pathology, University of Helsinki, Helsinki, Finland
,
E. J. Jokinen The Second and Third Depts. of Surgery, University Central Hospital, Helsinki, and the Second Dept. of Pathology, University of Helsinki, Helsinki, Finland
&
J. Ahlqvist The Second and Third Depts. of Surgery, University Central Hospital, Helsinki, and the Second Dept. of Pathology, University of Helsinki, Helsinki, Finland
 show all
Pages 377-383 | Received 02 Feb 1971, Accepted 05 Apr 1971, Published online: 25 Feb 2010

REFERENCES

  • Abouna, R., Kirkley, J. & Walder, D. N. 1969. Hepatic coma due to fulminating hepatitis treated with extracorporeal pig-liver perfusion. Brit. J. Surg. 56, 223–225.
  • Bert, J. M., Romieu, Cl., Pujol, H. Solassol, 1968. Épuration par perfusion de foie hétérogue pour agiocholite urémigène gravissime. gue pour angiocholite urémigène gravissime. Rev. méd.-chir. Mal. Foie 43, 153–164.
  • Condon, R. E., Bombeck, C. T. & Steihmann, F. 1970. Heterologous bovine liver perfusion therapy of acute hepatic failure. Amer. J. Surg. 119, 147–153.
  • Drapanas, T., Zemel, R. & Vang, J. 1966. Hemodynamics of the isolated perfused pig liver. Metabolism according to routes of perfusion and rates of flow. Ann. Surg. 164, 522–537.
  • Eiseman, B. 1966. Treatment of hepatic coma by extracorporeal liver perfusion. Ann. roy. Coll. Surg. Engl. 38, 329–348.
  • Eiseman, B., Knipe, P., McColl, H. A. & Orloff, M. J. 1961. Isolated liver perfusion for reducing blood ammonia. Arch. Surg. 83, 356–363.
  • Eiseman, B., Liem, D. S. & Raffucci, F. 1965. Heterologous liver perfusion in treatment of hepatic failure. Ann. Surg. 162, 329–344.
  • Eiseman, B., van Wyk, J. & Griffen, W. O. 1966. Methods for extracorporeal hepatic assist. Surg. Gynec. Obstet. 123, 522–530.
  • Kammerell, B. 1969. Möglichkeiten und Grenzen der modernen Leberkoma-Therapic. Dtsch. med. Wschr. 94, 2235–2240.
  • Lempinen, M., Salmenkivi, K. & Sivula, A. 1971. Orthotopic liver transplantation in the pig. Acta chir. scand. 137, 265–270.
  • Liem, D. S., Waltuch, T. I. & Eiseman, B. 1964. Function of the ex-vivo pig liver perfused with human blood. Surg. Forum 15, 90–91.
  • Norman, J. C., Saravis, C. A., Brown, M. E. & McDermott, W. V., Jr. 1966. Immunochemical observations in clinical heterologous (xeno geneic) liver perfusions. Surgery 60, 179–190.
  • Parbhoo, S. 1970. Personal communication.
  • Trey, C., Lipworth, L., Chalmers, T. C., Davidson, C. S., Gottlieb, L. S., Popper, H. & Saunders, S. J. 1968. Fulminant hepatic failure, presumable contribution of halothane. New Engl. J. Med. 279, 798–801.
  • Trump, B. F., Goldblatt, P. J. & Stowell, R. E. 1965. Studies on necrosis of mouse liver in vitro. Ultrastructural alterations in the mitochondria of hepatic parenchymal cells. Lab. Invest. 14, 343–371.
  • Trump, B. F., Goldblatt, P. J. & Stowell, R. E. 1965. Studies of necrosis in vitro of mouse hepatic parenchymal cells. Ultrastructural and cytochemical alterations of cytosomes, cyto-segresomes, multivascular bodies, microbodies and their relation to the lysosome concept. Lab. Invest. 14, 1946–1968.
  • Trump, B. F., Goldblatt, P. J. & Stowell, R. E. 1965. Studies of necrosis in vitro of mouse hepatic parenchymal cells. Ultrastructural alterations in endoplasmis reticulum, Golgi apparatus, plasma membranes and lipid droplets. Lab. Invest. 14, 2000–2028.
  • Watts, J. McK., Douglas, M. C., Dudley, H. A. F., Curr, F. W. & Owen, J. A. 1967. Heterologous liver perfusion in acute hepatic failure. Brit. med. J. 2, 341–345.

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