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Scandinavian Journal of Gastroenterology Volume 24, 1989 - Issue sup164
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Original Article

Rioprostil, a New Prostaglandin E1, Prevents Cyclosporin A-Induced Damage to Endocrine and Exocrine Pancreas

M. Müller Division of Gastroenterology, Department of Medicine, Department of Surgery, University of Essen and Department of Pathology, University of Hamburg, FRG
,
H. Degenhardt Division of Gastroenterology, Department of Medicine, Department of Surgery, University of Essen and Department of Pathology, University of Hamburg, FRG
,
K. Bergmann Division of Gastroenterology, Department of Medicine, Department of Surgery, University of Essen and Department of Pathology, University of Hamburg, FRG
,
H. Coone Division of Gastroenterology, Department of Medicine, Department of Surgery, University of Essen and Department of Pathology, University of Hamburg, FRG
,
M. Löhr Division of Gastroenterology, Department of Medicine, Department of Surgery, University of Essen and Department of Pathology, University of Hamburg, FRG
,
G. Klöppel Division of Gastroenterology, Department of Medicine, Department of Surgery, University of Essen and Department of Pathology, University of Hamburg, FRG
&
H. Goebell Division of Gastroenterology, Department of Medicine, Department of Surgery, University of Essen and Department of Pathology, University of Hamburg, FRG
 show all
Pages 35-41 | Published online: 08 Jul 2009

References

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  • Coelle E F, Adham N, Elashoff J, Lewin K, Taylor I L. Effects of prostaglandin and indomethacin on diet-induced acute pancreatitis in mice. Gastroenterology 1983; 85: 1307–1312
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  • Shriver D A, Rosenthale M E, Kluender H C, Schut R N, McGuire J L, Hong E. Pharmacology of rio-prostil, a new gastric cytoprotective/antisecretory agent. Arzneim Forsch/Drug Res 1985; 35(I)5, 839–843
  • Demol P, Wingender W, Weihrauch T R, Graefe K H. Inhibition of gastric secretion in man by rio-prostil, a new synthetic methyl prostaglandin E. Arzneim Forsch/Drug Res 1985; 35(I)5, 861–863
  • Müller M K, Demol P, Fladrich G, Goebell H, Pederson R A. Glucose-dependent insulinotropic action of cholecystokinin octapeptide in the isolated perfused rat pancreas. Digestion 1983; 27: 245–251
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  • Helmchen U, Schmidt W E, Siegel E G, Creutzfeldt W. Morphological and functional changes of pancreatic B cells in cyclosporin A-treated rats. Dia-betologia 1984; 27: 416–418
  • Hahn H J, Laube F, Lucke S, Klöting I, Kohnert K D, Warzock R. Toxic effects of cyclosporin on the endocrine pancreas of Wistar rats. Transplantation 1986; 41: 44–47
  • Yale J F, Roy R D, Grose M, Seemayer T A, Murphy G F, Marliss E B. Effects of cyclosporin on glucose tolerance in the rat. Diabetes 1985; 34: 1309–1313
  • Homan W P, Fabre J W, Williams K A, Millard P R, Morris P J. Studies on the immunosuppressive properties of cyclosporin A in rats receiving renal allografts. Transplantation 1980; 29: 361–366
  • Himal H S, Mowat C. Prostaglandin cytoprotection and lysosomal stability in acute canine gastric erosions. Can J Surg 1983; 26: 142–143
  • Taylor I L, Coelle E F, Adham N F. Factors that modify the effects of prostaglandin on diet-induced acute pancreatitis in mice. Scand J Gastroenterol 1985; 20(Suppl 112)101–105
  • Stiller C R, Dupre J, Gent M, et al. Effects of cyclosporin immunosuppression in insulin-dependent diabetes mellitus of recent onset. Science 1984; 223: 1362–1367
  • Beveridge T. Clinical transplantation–overview. Prog Allergy 1986; 38: 269–292

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