1
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Clinical Aspects of Cholecystokinin Release and Gallbladder Contraction

, , &
Pages 19-26 | Published online: 08 Jul 2009

References

  • Ivy A C, Oldberg E. A hormone mechanism for gallbladder contraction and evacuation. Am J Physiol 1928; 86: 599–613
  • Byrnes D J, Henderson L, Borody T, Rehfeld J F. Radioimmunoassay of cholecystokinin in human plasma. Clin Chim Acta 1981; 111: 81–89
  • Schafmayer A, Werner M, Becker H D. Radioimmunological determination of cholecystokinin in tissue extracts. Digestion 1982; 24: 146–154
  • Jansen J BMJ, Lamers C BHW. Radioimmunoassay of cholecystokinin in human tissue and plasma. Clin Chim Acta 1983; 131: 305–316
  • Fried G M, Ogden W D, Swierczek J, et al. Release of cholecystokinin in concious dogs: correlation with simultaneous measurements of gallbladder pressure and pancreatic protein secretion. Gastroenterology 1983; 85: 1113–1119
  • Cantor P. Evaluation of radioimmunoassay for cholecystokinin in human plasma. Scand J Clin Lab Invest 1986; 46: 213–221
  • Yamamura T, Takahashi T, Kusonoki M, Kantoh M, Seino Y, Utsonomiya J. Gallbladder dynamics and plasma cholecystokinin responses after meals, oral water, or sham feeding in healthy subjects. Am J Med Sci 1988; 295: 102–107
  • Kramhoft J, Balslev I. Hindahl F, Backer OG. Vagotomy and function of the gallbladder. Scand J Gastroenterol 1972; 7: 102–112
  • Palframan A, Meire H B. Real time ultrasound. A new method for studying gallbladder kinetics. Br J Radiol 1979; 52: 801–803
  • Everson G T, Braverman D Z, Johnson M L, Kern F, Jr. A critical evaluation of real-time ultrasonography for the study of gallbladder volume and contraction. Gastroenterology 1980; 79: 40–46
  • Wiener J, Inoue K, Fagan C J, Lilja P, Watson L C, Thompson J C. Release of cholecystokinin in man: correlation of blood levels with gallbladder contraction. Ann Surg 1981; 194: 321–325
  • Hopman W PM, Brouwer W FM, Rosenbusch G, Jansen J BMJ, Lamers C BHW. A computerized method for rapid quantification of gallbladder volume from real-time ultrasounds. Radiology 1985; 154: 236–237
  • Dodds W J, Groh W J, Darweesh R MA, Lawson T L, Kishk M SA, Kern M K. Sonographic measurement of gallbladder volume. AJR 1985; 145: 1009–1011
  • Spellman S J, Shaffer E A, Rosenthall L. Gallbladder emptying in response to cholecystokinin. A cholescintigraphic study. Gastroenterology 1979; 77: 115–120
  • Krishnamurthy G T, Bobba V R, Kingston E. Radionuclide ejection fraction: a technique for quantitative analysis of motor function of the human gallbladder. Gastroenterology 1981; 80: 482–490
  • Sarva R P, Shreiner D P, van Thiel D, Yingvorapant N. Gallbladder function: methods for measuring filling and emptying. J Nucl Med 1985; 26: 140–144
  • Masclee A AM, Jansen J BMJ, Driessen W MM, Geuskens C M, Lamers C BHW. Gallbladder and cholecystokinin responses to intraduodenal fat in asymptomatic gallstone patients. Neth J Med 1986; 29: 254
  • Mackie C R, Baxter J N, Grime J S, Hulks G, Cusch-Ieri A. Gallbladder emptying in normale subjects–a data base for clinical cholescintigraphy. Gut 1987; 28: 137–141
  • Masclee A AM, Hopman W PM, Corstens F HM, et al. Simultaneous measurement of gallbladder emptying by cholescintigraphy and ultrasonography: comparison of two techniques. Neth J Med 1989, (in press)
  • Hansen W E, Maurer H, Haberland H. The effect of sham-feeding on gallbladder volume and circulation of bile acids. Hepatogastroenterology 1982; 29: 108–110
  • Fisher R S, Rock E, Malmud L S. Gallbladder emptying response to sham feeding in humans. Gastroenterology 1986; 90: 1854–1857
  • Hopman W PM, Jansen J BMJ, Rosenbusch G, Lamers C BHW. Cephalic stimulation of gallbladder contraction in humans: role of cholecystokinin and the cholinergic system. Digestion 1987; 38: 197–203
  • Baxter J N, Grime J S, Critchley M, Shields R. Relationship between gastric emptying of solids and gallbladder emptying in normal subjects. Gut 1985; 26: 342–351
  • Debas H T, Yamagishi T. Evidence of a pylo-rocholecystic reflex for gallbladder contraction. Ann Surg 1979; 170–176
  • Hopman W PM, Jansen J BMJ, Rosenbusch G, Lamers C BHW. Effect of equimolar amounts of long-chain triglycerides and medium-chain triglycerides on plasma CCK and gallbladder contraction. Am J Clin Nutr 1984; 39: 356–359
  • Liddle R A, Goldfine I D, Rosen M S, Taplitz R A, Williams J A. Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction. J Clin Invest 1985; 75: 1142–1152
  • Kerstens P JSM, Lamers C BHW, Jansen J BMJ, de Jong A JL, Hessels M, Hafkenscheid J CM. Physiological plasma concentrations of cholecystokinin stimulate pancreatic enzyme secretion and gallbladder contraction in man. Life Sci 1985; 36: 565–569
  • Lilja P, Fagan C J, Wiener I, et al. Infusion of pure CCK in humans: correlation between plasma concentrations of CCK and gallbladder size. Gastroenterology 1982; 83: 256–261
  • Maton P N, Selden A C, Fitzpatrick M L, Chadwick V S. Infusion of cholecystokinin octapeptide in man: relation between plasma cholecystokinin concentrations and gallbladder emptying rates. Eur J Clin Invest 1984; 14: 37–41
  • Hopman W PM, Kerstens P JSM, Jansen J BMJ, Rosenbusch G, Lamers C BHW. Effect of graded physiologic doses of cholecystokinin on gallbladder contraction measured by ultrasonography. Gastroenterology 1985; 89: 1242–1247
  • Fried G M, Ogden W D, Sakamoto T, Greeley G H, Jr., Thompson J C. Experimental evidence for a vagally mediated and cholecystokinin independent enteropancreatic reflex. Ann Surg 1985; 202: 69–74
  • Brugge W R, Burke C A, Izzo R S, Praissman M. Role of cholecystokinin in intestinal phase of human pancreatic secretion. Dig. Dis Sci 1987; 32: 155–163
  • Gullo L, Bolondi L, Priori P, Casanova P, Labo G. Inhibitory effect of atropine on cholecystokinin-induced gallbladder contraction in man. Digestion 1984; 29: 209–213
  • Marzio L, Digiammarco A M, Neri M, Cuccurollo F, Malfertheiner P. Atropine antagonizes cholecystokinin and caerulein induced gallbladder evacuation in man: a real-time ultrasonographic study. Am J Gastroenterol 1985; 80: 1–4
  • Hopman W PM, Jansen J BMJ, Rosenbusch G, Lamers C BHW. Role of cholecystokinin and the cholinergic system in the intestinal phase of gallbladder contraction in man. Gut 1986; 27: A603
  • Ihasz M, Griffith C A. Gallstones after vagotomy. Am J Surg 1981; 141: 141–150
  • Fisher R S, Rock E, Malmud L S. Cholinergic effects on gallbladder emptying in humans. Gastroenterology 1985; 89: 716–722
  • Inberg M V, Vuorio M. Human gallbladder function after selective gastric and total abdominal vagotomy. Acta Chir Scand 1969; 135: 625–633
  • Kramhoft J, Balslev I, Lindahl F, Bavker O G. Vagotomy and function of the gall-bladder. Scand J Gastroenterol 1972; 7: 109–112
  • Parkin G JS, Smith R B, Johnston D. Gallbladder volume and contractility after truncal, selective and highly selective (parietal-cell) vagotomy in man. Ann Surg 1973; 178: 581–586
  • Khalil T, Walker J P, Wiener I, et al. Effect of aging on gallbladder contraction and release of cholecystokinin 33 in humans. Surgery 1985; 98: 423–429
  • Becker H D, Werner M, Schafmayer A. Release of radioimmunologic cholecystokinin in human subjects. Am J Surg 1984; 147: 124–129
  • Masclee A AM, Geuskens L M, Driessen W MM, Jansen J BMJ, Lamers C BHW. Effect of aging on plasma cholecystokinin secretion and gallbladder emptying. Age 1988; 11: 136–140
  • Masclee A AM, Jansen J BMJ, Driessen W MM, Geuskens L M, Lamers C BHW. Plasma cholecystokinin and gallbladder responses to intra-duodenal fat in gallstone patients. Dig Dis Sci 1989; 34: 353–359
  • Fisher R S, Stelzer F, Rock E, Malmud L S. Abnormal gallbladder emptying in patients with gallstones. Dig Dis Sci 1982; 27: 1019–1024
  • Forgacs I C, Maisey M N, Murphy G M, Dowling R H. Influence of gallstones and ursodeoxycholic acid therapy on gallbladder emptying. Gastroenterology 1984; 87: 299–307
  • Bobba V R, Krishnamurthy G T, Kingston E, Turner F E, Brown P H, Langrell K. Gallbladder dynamics induced by a fatty meal in normal subjects and patients with gallstones: concise communication. J Nucl Med 1984; 25: 21–24
  • Kishk S MA, Darweesh R MA, Dodds W J, et al. Sonographic evaluation of resting gallbladder volume and postprandial emptying in patients with gallstones. AJR 1987; 148: 875–879
  • Thompson J C, Fried G M, Ogden W D, et al. Correlation between release of cholecystokinin and contraction of the gallbladder in patients with gallstones. Ann Surg 1982; 195: 670–675
  • Doty J E, Pitt H A, Kuchenbecker L, DenBesten L. Impaired gallbladder emptying before gallstone formation in the prairie dog. Gastroenterology 1983; 85: 168–174
  • Brugge W R, Brand D L, Atkins H L, Lane B L, Abel W G. Gallbladder dyskinesia in chronic acalculous cholecystitis. Dig Dis Sci 1986; 31: 461–467
  • Calam J, Ellis A, Dockray G J. Identification and measurement of molecular variants of cholecystokinin in duodenal mucosa and plasma. J Clin Invest 1982; 69: 218–225
  • Maton P N, Selden A C, Fitzpatrick M L, Chad-Wick V S. Defective gallbladder emptying and cholecystokinin release in celiac disease. Gastroenterology 1985; 88: 391–396
  • Jansen J BMJ, Hopman W PM, Lamers C BHW. Impaired cholecystokinin secretion and gallbladder contraction in response to intraduodenal fat in patients with coeliac disease. Digestion 1984; 30: 95
  • Brown A M, Bradshaw M J, Richardson R, Wheeler J G, Harvey R F. Pathogenesis of the impaired gallbladder contraction of coeliac disease. Gut 1987; 28: 1426–1432
  • Harvey R F, Dowsett L, Hartog M, Read A E. A radioimmunoassay for cholecystokinin-pancreo-zymin. Lancet 1973; 2: 826–828
  • Harvey R F, Rey J F, Howard J M, et al. Bioassay and radioimmunoassay of serum cholecystokinin in patients with pancreatic disease. Rend Gastroenterol 1977; 9: 15–16
  • Elderle A, Vantini J, Harvey R F, et al. Fasting serum cholecystokinin levels in chronic relapsing pancreatitis. Ir J Med Sci 1977; 146: 30
  • Slaff J I, Wolfe M M, Toskes P P. Elevated fasting cholecystokinin levels in pancreatic exocrine impairment: evidence to support feedback regulation. J Lab Clin Med 1985; 105: 282–285
  • Schafmayer A, Becker H D, Werner M, Folsch U R, Creutzfeldt W. Plasma cholecystokinin levels in patients with chronic pancreatitis. Digestion 1985; 32: 136–139
  • Bozkurt T, Adler G, Koop I, Koop H, Tiirmer W, Arnold R. Plasma CCK levels in patients with pancreatic insufficiency. Dig Dis Sci 1988; 33: 276–281
  • Cantor P, Petronijevic L, Worning H. Plasma cholecystokinin concentrations in patients with advanced chronic pancreatitis. Pancreas 1986; 1: 488–493
  • Jansen J BMJ, Hopman W PM, Lamers C BHW. Plasma cholecystokinin concentrations in patients with pancreatic insufficiency measured by sequence-specific radioimmunoassays. Dig Dis Sci 1984; 29: 1109–1117
  • Byrnes D J, Borody T, Henderson L. Plasma cholecystokinin. Regul Pept 1980; S15, (suppl 1)
  • Jansen J BMJ, Jebbink M CW, Lamers C BHW. Effect of pancreatic enzymes on postprandial plasma cholecystokinin secretion. Digestion 1987; 38: 26–27
  • Funakoshi A, Nakano I, Shinozaki H, Ibayashi H, Tateishi K, Hamaoka T. Low plasma cholecystokinin response after ingestion of a test meal in patients with chronic pancreatitis. Am J Gastroenterol 1985; 80: 937–940
  • Masclee A AM, Jansen J BMJ, Corsten F HM, Lamers C BHW. Reversible gallbladder dysfunction in pancreatic insufficiency. Gut 1989; 30: 866–872
  • Meyer J H, Jones R S. Canine pancreatic responses to intestinally perfused fat and products of fat digestion. Am J Physiol 1974; 226: 1178–1187
  • Malagelada J R, Dimagno E P, Summerskill W HJ, Go V LW. Regulation of pancreatic and gallbladder functions by intra-luminal fatty acids and bile acids in man. J Clin Invest 1976; 58: 493–499
  • Hopman W PM, Jansen J BMJ, Lamers C BHW. Plasma cholecystokinin response to oral fat in patients with Billroth I and II gastrectomy. Ann Surg 1984; 199: 276–280
  • Inoue K, Fuchigami A, Hosotani R, et al. Release of cholecystokinin and gallbladder contraction before and after gastrectomy. Ann Surg 1987; 205: 27–32
  • Masclee A AM, Jansen J BMJ, Driessen W MM, Geuskens L M, Lamers C BHW. Delayed plasma cholecystokinin and gallbladder responses to intestinal fat in patients with Billroth I and II gastrectomy. Surgery 1989, (in press)
  • Singer M V, Solomon T E, Wood J, Grossman M I. Latency of pancreatic enzyme response to intraduodenal stimulants. Am J Physiol 1980; 238: G23–G29
  • Lamers C BHW, Diemel C M, Jansen J BMJ. Serum pancreatic polypeptide responses to food and secretin in patients with Billroth I and Billroth II gastrectomies and in normal subjects. Surgery 1982; 91: 288–292
  • Hopman W PM, Jansen J BMJ, Lamers C BHW. Plasma cholecystokinin response to a liquid fat meal in vagotomized patients. Ann Surg 1984; 200: 693–697
  • Fried G M, Ogden W D, Fagan C J, Inoue K, Greeley G, Thompson J C. Plasma concentrations of chole cystokinin in patients with duodenal ulcer disease. Surgery 1984; 95: 27–33
  • Masclee A AM, Jansen J BMJ, Driessen W MM, Geuskens L M, Lamers C BHW. Effect of truncal vagotomy on cholecystokinin release, gallbladder contraction and gallbladder sensitivity to cholecystokinin in humans. Neth J Med 1989, in press
  • Tinker J, Cox A G. Gallbladder function after vagotomy. Br J Surg 1969; 56: 779–782
  • Malagelada J W, Go V LW, Summerskill W HJ. Altered pancreatic and biliary function after vagotomy and pyloroplasty. Gastroenterology 1974; 66: 22–27
  • Villanova M G, Meneghelli U G, Dantas R O. Gallbladder motor function in Chagasic patients with megacolon and/or megaesophagus. Digestion 1987; 36: 189–194
  • Stone B G, Gavaler J S, Belle S H, et al. Impairment of gallbladder emptying in diabetes mellitus. Gastroenterology 1988; 95: 170–176
  • Braverman D Z. The lack of effect of meto-clopramide on gallbladder volume and contraction in diabetic cholecystoparesis. Am J Gastroenterol 1986; 81: 960–962

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.