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Original Article

The Effect of Vasoactive Intestinal Peptide, Secretin, and Glucagon on Human Duodenal Bicarbonate Secretion

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Pages 151-157 | Received 01 Aug 1988, Accepted 10 Oct 1988, Published online: 08 Jul 2009

References

  • Flemstrom G. Gastric and duodenal mucosal bicarbonate secretion. Phvsioloev of the gastrointestinal tract, L R Johnson. Raven Press, New York 1987; 1011–30
  • Isenberg J I, Hogan D L, Koss M A, Selling J A. Human duodenal mucosal bicarbonate secretion Evidence for basal secretion and stimulation by hydrochloric acid and a synthetic prostaglandin E, analogue. Gastroenterology 1986; 91: 370–378
  • Isenberg J I, Selling J A, Hogan D L, Koss M A. Impaired proximal duodenal mucosal bicarbonate secretion in patients with duodenal ulcer. N Engl J Med 1987; 316: 374–379
  • Flemstrom G, Jedstedt G, Nylander O. Effects of some Opiates and vasoactive intestinal peptide on duodenal surface epithelial bicarbonate secretion in the rat. Scand J Gastroenterol 1985; 20(suppl 110)49–53
  • Flemstrom G, Heylings J R, Garner A. Gastric and duodenal HCO3-transport in vitro: effects on hormones and local transmitters. Am J Physiol 1982; 242: G100–G110
  • Flemstrom G, Kivilaakso E, Briden S, Nylander O, Jedstedt G. Gastroduodenal bicarbonate secretion in mucosal protection. Possible role of vasoactive intestinal peptide and opiates. Dig Dis Sci 1985; 30(suppl)63S–68S
  • Isenberg J I, Wallin B, Johansson C, Smedfors B, Mutt V, Tatemoto K, Emas S. Secretin, VIP and PHI stimulate rat proximal duodenal surface epithelial bicarbonate secretion in vivo. Regul Pept 1984; 8: 315–320
  • Kirkegaard P, Olsen P S, Nexo E, Holst J J, Poulsen S S. Effect of vasoactive intestinal peptide and somatostatin on secretion on epidermal growth factor and bicarbonate from Brunner's glands. Gut 1984; 25: 1225–1229
  • Kirkegaard P, Lundberg J M, Poulsen S S, Olsen P S, Fahrenkrug J, Hokfelt T, Christiansen J. Vasoactive intestinal polypeptidergic nerves and Brunner's gland secretion in the rat. Gastroenterology 1981; 81: 872–878
  • Polak J, Colling I, Bloom S, Pearse A. Immuno-fluorescent localization of secretin and entero-glucagon in human intestinal mucosa. Scand J Gastroenterol 1971; 6: 739–744
  • Petersen H. The effect of pure natural secretion on the bicarbonate secretion into the duodenum in man. Scand J Gastroenterol 1970; 5: 105–111
  • Konturek S J, Bilski J J, Tasler J, Laskiewicz J. Gut hormones in the stimulation of gastroduodenal alkaline secretion in conscious dogs. Am J Physiol 1985; 248: G687–G691
  • Flemstrom G, Garner A, Nylander O, Hurst B C, Heylings J R. Surface epithelial HCO3-transport by mammalian duodenum in vivo. Am J Physiol 1982; 243: G348–G358
  • Dockray G J. Physiology of enteric neuropeptides. Physiology of the gastrointestinal tract. 2nd ed, L R Johnson. Raven Press, New York 1987; 41–66
  • Preshaw R M, Grossman M I. Comparison of subcutaneous and intravenous administration of pancreatic stimulants. Am J Physiol 1965; 209: 803–810
  • George J D. New clinical method for measuring the rate of gastric emptying: the double sampling test meal. Gut 1968; 9: 237–242
  • Knutson L, Flemstrom G, Gustavsson S, Jedstedt G, Lonnerholm G. HCO3-secretion in rat duodenum after treatment with omeprazole and ranitidine. Scand J Gastroenterol 1987; 22: 87–90
  • Gaginella T S, Mekhjian H S, O'Dorisio T M. Vasoactive intestinal peptide: quantification by radioimmunoassay in isolated cells, mucosa, and muscle of the hamster intestine. Gastroenterology 1978; 74: 718–721
  • Glucagon kit brochure. Radioassay System Laboratories, Inc., Carson, Calif 1982
  • Armitage P. Statistical methods in medical research. Blackwell Scientific, Boston, Mass. 1980
  • Holst J. Gut glucagon, enteroglucagon, gut glu-cagonlike immunoreactivity, glicentin—current status. Gastroenterology 1983; 84: 1602–1613
  • Walsh J H. Gastrointestinal hormones. Physiology of the gastrointestinal tract. 2nd ed, L R Johnson. Raven Press, New York 1987; 181–253
  • Camilleri M, Cooper B T, Adrian T E, Bloom S R, Chadwick V S. Effects of vasoactive intestinal peptide and pancreatic polypeptide in rabbit intestine. Gut 1981; 22: 14–18
  • Krejs G J, Fordtran J S, Bloom S R, Fahrenkrug J, Schaffalitzky de Muckadell O B, Fisher J E, Humphrey C S, et al. Effect of VIP infusion on water and ion transport in the human jejunum. Gastroenterology 1980; 78: 722–727
  • Schaffalitzky de Muckadell O B, Fahrenkrug J, Holst J J, Lauritsen K B. Release of vasoactive intestinal polypeptide (VIP) by intraduodenal stimuli. Scand J Gastroenterol 1977; 12: 793–799
  • Shinomura Y, Himino S, Takahashi S, Kuroshima T, Okumo M, Kamayama S, Tsuji K, et al. Release of vasoactive intestinal peptide by intraduodenal infusion of HCl or fat and intramuscular neo-stigmine in man. Hepatogastroenterology 1985; 32: 129–132
  • Algazi M C, Pandol S J, Rivier J, Isenberg J I. Vasoactive intestinal peptide is a mediator of H+-induced duodenal bicarbonate secretion (abstract). Gastroenterology 1987; 92: 1796
  • Smedfors B, Theodorsson-Norheim E, Panja A, Johansson C. Vasoactive intestinal peptide participates in regulating H+ stimulated HCO3−secretion in the proximal duodenum of the conscious rat (abstract). Gastroenterology 1987; 92: 1645
  • You C H, Rominger J M, Chey W Y. Potentiation effect of cholecystokinin-octapeptide on pancreatic bicarbonate secretion stimulated by a physiologic dose of secretin in humans. Gastroenterology 1983; 85: 4045
  • Petersen H, Berstad A. Comparison of response to intravenous injection and infusion of secretin in man. Scand J Gastroenterol 1972; 7: 463–469
  • Case R M, Garner A, Uddin K K. Simultaneous determination of duodenal and pancreatic bicarbonate transport: differential effects of secretin and prostaglandin E2 in the cat in vivo. J Physiol 1983; 340: 36P–37P
  • Christiansen J, Holst J J, Kalaja E. Inhibition of gastric acid secretion in man by exogenous and endogenous pancreatic glucagon. Gastroenterology 1976; 70: 688–692
  • Domschke S, Domschke W, Rosch W, Konturek S J, Wunsch E, Demling L. Bicarbonate and cyclic AMP content of pure human pancreatic juice in response to graded doses of synthetic secretin. Gastroenterology 1976; 70: 533–536

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