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Original Article

Time-Specific Development of Pancreatic Hypersecretory Capacity during Chronic Caerulein Treatment in Rats

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Pages 565-570 | Received 25 Oct 1988, Accepted 07 Feb 1989, Published online: 08 Jul 2009

References

  • Anastasi A, Erspamer V, Endean R. Isolation and amino acid sequence of caerulein, the active deca-peptide, from skin of Hyla caerulea. Arch Biochem Biophys 1968; 125: 57–68
  • Solomon TE. Regulation of exocrine pancreatic cell proliferation and enzyme synthesis. Physiology of the gastrointestinal tract, L R Johnson. Raven Press, New York 1981; 873–892
  • Fölsch UR. Regulation of pancreatic growth. Clin Gastroenterol 1983; 13: 679–699
  • Solomon T E, Vanier M, Morisset J. Cell site and time course of DNA synthesis in pancreas after caerulein and secretin. Am J Physiol 1983; 245: G99–G105
  • Delhaye M, Taton G, Poirier G, Larose L, St-James S, Morisset J. Modulation of rat pancreatic mucarinic cholinergic receptors by caerulein. Biochem Pharmacol 1985; 34: 1057–1063
  • Petersen H, Solomon T, Grossman MI. Effect of chronic pentagastrin, cholecystokinin, and secretin on pancreas of rats. Am J Physiol 1978; 234: E286–E293
  • Petersen H, Solomon T E, Grossman MI. Pancreatic secretion in rats after chronic treatment with secretin plus caerulein. Gastroenterology 1979; 76: 790–794
  • Otsuki M, Williams JA. Amylase secretion by isolated pancreatic acini after chronic cholecystokinin treatment in vivo. Am J Physiol 1983; 244: G683–G688
  • Varga G, Scarpignato C, Papp M. Inhibition of pancreatic secretory and trophic response to caerulein by a H2-receptor antagonist ranitidine in the rat. Digestion 1985; 31: 177–182
  • Varga G, Papp M, Solomon T E, Scarpignato C, Toth I E, Szabo D. Caerulein in supramaximal doses fails to stimulate pancreatic growth, but it forces secretory granulopoiesis. Acta Physiol Hung 1988; 71: 99–106
  • Lowry O H, Rosenbergh N J, Farr A L, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265–275
  • Hummel BC. A modified spectrophotometric method for determination of chymotrypsin, trypsin and thrombin. Can J Biochem Phvsiol 1959; 37: 1393–1399
  • Solomon T E, Petersen H, Elashoff J, Grossman MI. Interaction of caerulein and secretin on pancreatic size and composition in rat. Am J Physiol 1978; 235: E714–E719
  • Munro H N, Fleck A. Recent development in the measurement of nucleic acids in biological materials. Analyst 1966; 91: 78–88
  • Burton K. A study of the conditions and mechanisms of the diphenylamine reaction for the color-imetric estimation of deoxyribonucleic acid. Biochem J 1956; 62: 315–323
  • Dunnett CW. A multiple comparison procedure for comparing several treatments with a control. J Am Statist Assoc 1955; 50: 1096–1121
  • Harper S L, Granger D N, Barrowman J A, Kvietys P R, Ulrich MG. Relation between pancreatic growth and blood flow. Am J Physiol 1985; 248: G61–G67
  • De Caro G, Importa G. Disappearance of caerulein from circulating blood and its inactivation in vitro by tissue homogenates and blood of dogs and rats. Arch Int Pharmacodyn Ther 1972; 197: 166–174
  • Tokiwa T, Uemura I, Murakami H, et al. Studies on caerulein (FI6934). Absorption, distribution, metabolism and excretion of caerulein. Jpn J Pharmacol 1975; 747–762
  • Morisset J A, Webster PD. In vitro and in vivo effects of pancreozymin, urecholine, and cyclic AMP on rat pancreas. Am J Physiol 1971; 230: 201–208
  • Varga G, Papp M, Folly G, Dobronyi I. Development of pancreatic hypersecretory state for chronic caerulein treatment in rats. Digestion 1988; 40: 133–134

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