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Original Article

High-Performance Liquid Chromatography of Bilirubin Conjugates in Bile: Effect of β-Glucuronidase on the Bile Pigments

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Pages 657-665 | Received 15 Dec 1988, Accepted 07 Feb 1989, Published online: 08 Jul 2009

References

  • Wosiewitz U, Schroebler S. On the chemistry of ‘black’ pigment stones from the gallbladder. Clin Chim Acta 1978; 89: 1–12
  • Suzuki N. On black pigment of gallstones, with special reference to comparison with bilirubin derivatives. Tohoku J Exp Med 1965; 85: 396–405
  • Malet P F, Takabayashi A, Trotman B W, Soloway R D, Weston N E. Black and brown pigment gallstones differ in microstructure and microcom-position. Hepatology 1984; 4: 227–234
  • Soloway R D, Trotman B W, Ostrow J D. Pigment gallstones. Gastroenterology 1977; 72: 167–182
  • Maki T. Pathogenesis of calcium bilirubinate gallstone: role of E. coli, beta-glucuronidase and coagulation by inorganic ions, polyelectrolytes and agitation. Ann Surg 1966; 164: 90–100
  • Tabata M, Nakayama F. Bacteria and gallstones. Etiological significance. Dig Dis Sci 1981; 26: 218–224
  • Skar V, Skar A G, Strømme J H. Beta-glucuronidase activity related to bacterial growth in common bile duct bile in gallstone patients. Scand J Gastro-enterol 1988; 23: 83–90
  • Skar V, Skar A G, Midtvedt T, Osnes M. Bacterial growth in the duodenum and in the bile of patients with gallstone disease treated with endoscopic papil-lotomy (EPT). Endoscopy 1986; 18: 10–13
  • Bergesen Ø, Schjønsby H, Schjerven L. Effect of bile fistulae on vitamin B12 absorption in rats. Scand J Gastroenterol 1985; 20: 589–594
  • Heirwegh K PM, Fevery J, Meuwissen J ATP, et al. Recent advances in the separation and analysis of diazo-positive bile pigments. Methods Biochem Anal 1974; 22: 205–250
  • Saxerholt H, Midtvedt T, Gustafsson B E. Methods for determination of conjugated bilirubin in rat faeces. Scand J Clin Lab Invest 1984; 44: 565–571
  • Heirwegh K PM, Fevery J, Michiels R, Van Hees G P, Compernolle F. Separation by thin-layer chromatography and structure elucidation of bilirubin conjugates isolated from dog bile. Biochem J 1975; 145: 185–199
  • Nosslin B. The direct diazo reaction on bile pigments in serum. Scand J Clin Lab Invest 1960; 12(suppl 49)1–176
  • Skar V, Skar A G, Midtvedt T, Løtveit T, Osnes M. Beta-glucuronidase producing bacteria in bile from the common bile duct in patients treated with endo-scopic papillotomy for gallstone disease. Scand J Gastroenterol 1986; 21: 253–256
  • Skar V, Skar A G, Bratlie J, Osnes M. Beta-glucuronidase activity in the bile of gallstone patients both with and without duodenal diverticula. Scand J Gastroenterol 1989; 24: 205–212
  • Rhoadcs H M, Overall J E. A sample size correction for Pearson chi-square in 2 × 2 contingency tables. Psycho1 Bull 1982; 91: 418–423
  • Gordon E R, Goresky C A. A rapid and quantitative high performance liquid chromatographic method for assaying bilirubin and its conjugates in bile. Can J Biochem 1982; 60: 1050–1057
  • Blanckaert N, Kabra P M, Farina F A, Stafford B E, Marton L J, Schmid R. Measurement of bilirubin and its monoconjugates and diconjugates in human serum by alkaline methanolysis and high-performance liquid chromatography. J Lab Clin Med 1980; 96: 198–212
  • Jansen P LM, Tangerman A. Separation and characterization of bilirubin conjugates by high-performance liquid chromatography. J Chromatogr 1980; 182: 100–104
  • Spivak W, Carey M C. Reverse-phase HPLC separation, quantification and preparation of bilirubin and its conjugates from native bile. Biochem J 1985; 225: 787–805
  • Onishi S, Ltoh S, Kawade N, Isobe K, Sugiyama S. An accurate and sensitive analysis by high pressure liquid chromatography of conjugated and uncon-jugated bilirubin IX-α in various biological fluids. Biochem J 1980; 185: 281–284
  • Heirwegh K PM, Blanckaert N. Analytical chemistry of rubins. Bilirubin, K PM Heirwegh, S B Brown. CRC Press, Boca Raton, Fla. 1982; Vol. 1: 125–151
  • Skar V, Schjøneberg A M, Saxerholt H, Midtvedt T, Osnes M. Quantification of bilirubin in bile with high performance liquid chromatography (HPLC) [Abstract]. Gastroenterol Int 1988; 1(suppl l)572
  • Fevery J, Vijver Van der, Michiels R, Heirwegh K PM. Comparison in different species of biliary bilirubin-IX α conjugates with the activities of hepatic and renal bilirubin-IX α-uridine diphosphate glycosyltransferases. Biochem J 1977; 164: 737–746
  • Boonyapisit S T, Trotman B W, Ostrow J D. Uncon-jugated bilirubin and the hydrolysis of conjugated bilirubin, in gallbladder bile of patients with cholelithiasis. Gastroenterology 1978; 74: 70–74
  • Brodersen R. Physical chemistry of bilirubin: binding to macromolecules and membranes. Bilirubin, K PM Heirwegh, S B Brown. CRC Press, Boca Raton, Fla. 1982; Vol. 1: 75–123
  • Oyabu H, Tabata M, Nakayama F. Nonbacterial transformation of bilirubin in bile. Dig Dis Sci 1987; 32: 809–816
  • Ho K-J, Hsu S-C, Chen J-S, Ho L-HC. Human biliary beta-glucuronidase: Correlation of its activity with deconjugation of bilirubin in the bile. Eur J Clin Invest 1986; 16: 361–367
  • Masuda H, Nakayama F. Composition of bile pigment in gallstones and bile and their etiological significance. J Lab Clin Med 1979; 93: 353–360
  • Trotman B W, Bernstein S E, Bove K E, Wirt G D. Studies on the pathogenesis of pigment gallstones in hemolytic anemia. Description and characteristics of a mouse model. J Clin Invest 1980; 65: 1301–1308
  • Skar V, Larsen S, Osnes M. The 1–g 14C-d-xylose breath test in gallstone patients with and without duodenal diverticula. Scand J Gastroenterol 1985; 20: 447–451
  • Skar V, Skar A G, Osnes M. The duodenal bacterial flora in the region of papilla of Vater in patients with and without duodenal diverticula. Scand J Gastroenterol 1989; 24: 649–656
  • Løtveit T, Osnes M, Aune S. Bacteriological studies of common duct bile in patients with gallstone disease and juxtapapillary duodenal diverticula. Scand J Gastroenterol 1978; 13: 93–95
  • Løtveit T, Osnes M, Aune S, Larsen S. Studies of the choledocho-duodenal sphincter in patients with and without juxtapapillary duodenal diverticula. Scand J Gastroenterol 1980; 15: 875–880
  • Viceconte G, Viceconte G W, Bogliolo G. Endo-scopic manometry of the sphincter of Oddi in patients with and without juxtapapillary duodenal diverticula. Scand J Gastroenterol 1984; 19: 329–333
  • Kubota K, Itoh T, Shibayama K, Shimada K, Nomura Y, Idezuki Y. Papillary function of patients with juxtapapillary duodenal diverticulum. Consideration of pathogenesis of common bile duct stones. Scand J Gastroenterol 1989; 24: 140–144
  • Løtveit T. The composition of biliary calculi in patients with juxtapapillary duodenal diverticula. Scand J Gastroenterol 1982; 17: 653–656
  • Beyler A L, Szego C M. Effect of normal and modified bovine serum albumin on β-glucuronidase activity. Fed Proc 1952; 11: 13
  • Marsh C A. Metabolism of D-glucuronolactone in mammalian systems. Biochem J 1963; 86: 77–86
  • Yamaguchi I, Sato T, Matsushiro T, Sato H. Quantitative determination of D-glucaric acid in bile in relation to inhibitory effect of bile on bacterial β-glucuronidase. Tohoku J Exp Med 1965; 87: 123–132
  • Gallinger S, Charvey P R, Petrunka C N, Strasberg S M. Effect of binding of ionised calcium on the in vitro nucleation of cholesterol and calcium bili-rubinate in human gall bladder bile. Gut 1986; 27: 1382–1386
  • Moore E W. The role of calcium in the Pathogenesis of gallstones: Ca+ + electrode studies of model bile salt solutions and other biological systems. Hepa-tology 1984; 4: 2228–2243
  • Moore E W, Celic L, Ostrow J D. Interactions between ionized calcium and sodium taurocholate: bile salts are important buffers for prevention of calcium-containing gallstones. Gastroenterology 1982; 83: 1079–1089

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