Effect of Chronic Ursocholic Acid Administration on Bile Lipid Composition and Bile Acid Pool Size in Gallstone Patients

References

• Thistle J L, Schoenfield L J. Induced alterations in composition of bile of persons having cholelithiasis. Gastroenterology 1971; 61: 488–496
   PubMed Web of Science ®Google Scholar
• Danziger R G, Hofmann A F, Schoenfield L J, Thistle J L. Dissolution of cholesterol gallstones by chenodeoxycholic acid. N Engl J Med 1972; 286: 1–8
   PubMed Web of Science ®Google Scholar
• Bell G D, Whitney B, Dowling R H. Gallstone dissolution in man using chenodeoxycholic acid. Lancet 1972; 2: 1213–1216
   PubMed Web of Science ®Google Scholar
• Schoenfield L J, Lachin J M, The Steering Committee, The National Cooperative Gallstone Study Group. Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: The National Cooperative Gallstone Study: a controlled trial of efficacy and safety. Ann Intern Med 1981; 95: 257–282
   PubMed Web of Science ®Google Scholar
• Makino I, Shinozaki K, Yoshino K, Nakagawa S. Dissolution of cholesterol gallstones by ursodeoxy-cholic acid. Jpn J Gastroenterol 1975; 72: 690–702
   PubMedGoogle Scholar
• Maton P N, Murphy G M, Dowling R H. Ursodeoxycholic acid treatment of gallstones. Dose-response study and possible mechanism of action. Lancet 1977; 2: 1297–1301
   PubMed Web of Science ®Google Scholar
• Tokyo Cooperative Gallstone Study Group. Efficacy and indications of ursodeoxycholic acid treatment for dissolving gallstones. A multicenter double-blind trial. Gastroenterology 1980; 78: 542–548
   PubMed Web of Science ®Google Scholar
• La Russo N F, Hoffman N E, Hofmann A F, North-field T C, Thistle J L. Effect of primary bile acid ingestion on bile metabolism and biliary lipid secretion in gallstone patients. Gastroenterology 1975; 69: 1301–1314
   PubMedGoogle Scholar
• La Russo N F, Szczepanik P A, Hofmann A F. Effect of deoxycholic acid ingestion on bile acid metabolism and biliary lipid secretion in normal subjects. Gastroenterology 1977; 72: 132–140
   PubMedGoogle Scholar
• Ahlberg J, Angelin B, Einarsson K, Hellstrom K, Leijd B. Influence of deoxycholic acid on biliary lipids in man. Clin Sci Mol Med 1977; 53: 249–256
   PubMedGoogle Scholar
• Carulli N, Ponz De Leon M, Zironi F, Iori R, Loria P. Bile acid feeding and hepatic sterol metabolism: effect of deoxycholic acid. Gastroenterology 1980; 79: 637–641
   PubMedGoogle Scholar
• Low-Beer T S, Pomare E W. Can colonic bacterial metabolites predispose to cholesterol gall stones. Br Med J 1975; 1: 438–448
   PubMedGoogle Scholar
• Di Donato P, Carubbi F, Ponz de Leon M, Carulli N. Effect of small doses of deoxycholic acid on bile cholesterol saturation in patients with liver cirrhosis. Gut 1986; 27: 23–28
   PubMedGoogle Scholar
• Lindblad L, Lundholm K, Schersten T. Influence of cholic and chenodeoxycholic acid on biliary cholesterol secretion in man. Eur J Clin Invest 1977; 7: 383–388
   PubMedGoogle Scholar
• Sama C, La Russo N F, Lopez del Pino V, Thistle J L. Effects of acute bile acid administration on biliary lipid secretion in healthy volunteers. Gastroenterology 1982; 82: 515–525
   PubMedGoogle Scholar
• Carulli N, Loria P, Bertolotti M, et al. Effects of acute changes of bile acid pool composition on biliary lipid secretion. J Clin Invest 1984; 74: 614–624
   PubMedGoogle Scholar
• Armstrong M J, Carey M C. The hydrophobic-hydrophilic balance of bile salts. Inverse correlation between reverse-phase high performance liquid chromatographic mobilities and micellar-solubilizing capacities. J Lipid Res 1982; 23: 70–80
   PubMed Web of Science ®Google Scholar
• Lanzini A, Northfield T C. Effect of ursodeoxycholic acid on biliary lipid coupling and on cholesterol absorption during fasting and eating in subjects with cholesterol gallstones. Gastroenterology 1988; 95: 408–416
   PubMed Web of Science ®Google Scholar
• Roda A, Hofmann A F, Mysels K J. The influence of bile acid structure on self-association in aqueous solutions. J Biol Chem 1983; 258: 6362–6370
   PubMed Web of Science ®Google Scholar
• Loria P, Carulli N, Medici G, et al. Effect of ursocholic acid on bile lipid secretion and composition. Gastroenterology 1986; 90: 865–874
   PubMedGoogle Scholar
• Gurantz D, Hofmann A F. Influence of bile acid structure on bile flow and biliary lipid secretion in the hamster. Am J Physiol 1984; 247: G736–G748
   PubMedGoogle Scholar
• Borgstrom B, Barrowman J, Krabisch L, Lindstrom M, Lillienau J. Effects of cholic acid, 7 beta-hydroxy- and 12 beta-hydroxy-isocholic acid on bile flow, lipid secretion and bile acid synthesis in the rat. Scand J Lab Invest 1986; 46: 167–175
   PubMed Web of Science ®Google Scholar
• Howard P J, Gleeson D, Murphy G M, Dowling R H. Ursocholic acid: bile acid and bile lipid dose response and clinical studies in patients with gall stones. Gut 1989; 30: 97–103
   PubMed Web of Science ®Google Scholar
• Lanzini A, Pigozzi G, Facchinetti D, et al. Ursocholic acid administration to gallstone patients: effect on biliary lipid composition, bile acid pattern and gallstone dissolution. Curr Ther Res 1986; 39: 8–18
   Google Scholar
• Zuin M, Podda M. Ursocholic acid: a new litholitic agent [Abstract]. Hepatology 1984; 4: 1060
   Google Scholar
• Duane W C, Adler R D, Bennion L J, Ginsberg R L. Determination of bile acid pool size in man: a simplified method with advantages of increased precision, shortened analysis time, and decreased isotope exposure. J Lipid Res 1975; 16: 155–158
   PubMed Web of Science ®Google Scholar
• Talalay P. Enzymic analysis of steroid hormones. Methods Biochem Anal 1960; 8: 119–143
   PubMedGoogle Scholar
• Haslewood G AD, Murphy G M, Richardson L M. A direct enzymatic assay for 7alpha-hydroxy bile acids and their conjugates. Clin Sci 1973; 44: 95–98
   PubMed Web of Science ®Google Scholar
• Roda A, Festi D, Sama C, et al. Enzymatic determination of cholesterol in bile. Chim Clin Acta 1975; 64: 337–341
   PubMed Web of Science ®Google Scholar
• Qureshi N Y, Murphy G M, Dowling R H. The enzymatic determination of total phospholipids in bile and in bile rich duodenal aspirate. Chim Clin Acta 1980; 105: 407–110
   PubMed Web of Science ®Google Scholar
• Hall C N, Lanzini A, Facchinetti D, Northfield T C. Application of simplified new methods of bile acid analysis to gastrointestinal fluids [Abstract]. Clin Sci 1983; 65: 57P
   Google Scholar
• Eneroth P. Thin-layer chromatography of bile acids. J Lipid Res 1963; 4: 11–16
   PubMed Web of Science ®Google Scholar
• Thomas P H, Hofmann A F. A simple calculation of the lithogenic index of bile: expressing biliary lipid composition on rectangular coordinates. Gastroenterology 1973; 65: 698–700
   PubMed Web of Science ®Google Scholar
• Hegardt F G, Dam H. The solubility of cholesterol in aqueous solutions of bile salts and lecithin. Z Ernahrungswiss 1971; 10: 223–233
   PubMedGoogle Scholar
• Holzbach R T, Narsh M, Olszewski M, Holan K. Cholesterol solubility in bile: evidence that supersaturated bile is frequent in healthy man. J Clin Invest 1973; 52: 1467–1479
   PubMed Web of Science ®Google Scholar
• Salvioli G, Lugli R, Pradelli J M, Frignani A, Boccalletti V. Urinary excretion of bile acids during acute administration in man. Eur J Clin Invest 1988; 18: 22–28
   PubMed Web of Science ®Google Scholar
• Borgstrom B, Krabisch L, Lindstrom M. Metabolism of cholate, 7beta-hydroxy- and 12beta-hydroxy-isocholates in the rat. Scand J Clin Lab Invest 1986; 46: 177–182
   PubMed Web of Science ®Google Scholar
• Heuman D M, Vlahcevic Z R, Bailey M L, Hylemon P B. Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat. Hepatology 1988; 8: 892–897
   PubMedGoogle Scholar
• Borgstrom B, Krabisch L, Lindstrom M, Lillienau J, Midtvedt T, Corrie M. Effect of feeding ursocholic acid to germ-free rats. Scand J Clin Lab Invest 1986; 46: 183–187
   PubMed Web of Science ®Google Scholar
• Leighton L S, Carey M C. Bile salt hydrophilicity determines whether the physical state of native hepatic bile is predominantly vesicular or micellar [Abstract]. Gastroenterology 1984; 86: 1157
   Google Scholar