Protective Effect of S-Adenosyl-L-Methionine in Hepatic Uroporphyria: Evaluation in an Experimental Model

References

• Hexachlorobenzene. Proceedings of an international symposium. 1986, C R Morris, J RP Cabral. IARC Scientific Publications, Lyon 1986, no. 77
   Google Scholar
• Elder G H. Porphyria caused by hexachlorobenzene and other polyhalogenated aromatic hydrocarbons. Handbook of experimental pharmacology. Vol 44. Heme and hemoproteins, F De Matteis, W N Aldridge. Springer-Verlag, Berlin 1978; 157–200
   Google Scholar
• Di Padova C, Marchesi L, Cainelli T, et al. Effects of phlebotomy on urinary porphyrin pattern and liver histology in patients with porphyria cutanea tarda. Am J Med Sci 1983; 285: 2–12
   PubMed Web of Science ®Google Scholar
• Marchesi L, Di Padova C, Cainelli T, et al. A comparative trial of desferrioxamine and hydroxychloroquine for treatment of porphyria cutanea tarda in alcoholic patients. Photodermatology 1984; 1: 286–292
   PubMedGoogle Scholar
• Cainelli T, Di Padova C, Marchesi L, et al. Hyd-roxychloroquine versus phlebotomy in the treatment of porphyria cutanea tarda. Br J Dermatol 1983; 108: 593–600
   PubMed Web of Science ®Google Scholar
• Del C, Battle A M, Stella A M, De Kaminsky A R, Kaminsky C, Mariano H G. Two cases of infantile porphyria cutanea tarda: Successful treatment with oral S-adenosyl-L-meihionine and low-dose oral chloroquine. Br J Dermatol 1987; 116: 407–415
   PubMed Web of Science ®Google Scholar
• Giulidori P, Galli-Kienle M, Catto E, Stramentinoli G. Transmethylation, transsulfuration, and amino-propylation reactions of S-adenosyl-L-methionine in vivo. J Biol Chem 1984; 259: 4205–4211
   PubMed Web of Science ®Google Scholar
• Frezza M, Pozzato G, Chiesa L, Stramentinoli G, Di Padova C. Reversal of intrahepatic cholestasis of pregnancy in women after high dose S-adenosyl-L-methionine administration. Hepatology 1984; 4: 274–278
   PubMed Web of Science ®Google Scholar
• Frezza M, Di Fadova C. Italian study group for SAMe in liver disease. Multicenter placebo controlled clinical trial of intravenous and oral s-adeno-sylmethionine (SAMe) in cholestatic patients with liver disease. Hepatology 1987; 7: 1105
   Web of Science ®Google Scholar
• Smith A G, Francis J E, Kay S JE, Greig J B, Stewart F P. Mechanistic studies of the inhibition of hepatic uroporphyrinogen decarboxylase in C57BL/10 mice by iron-hexachlorobenzene synergism. Biochem J 1986; 238: 871–878
   PubMed Web of Science ®Google Scholar
• Rizzardini M, Graziani A, Carugo C, Cantoni L. Investigations on the role of free radical processes in hexachlorobenzene-induced porphyria in mice. J Biochem Toxicol 1988; 3: 33–46
   PubMedGoogle Scholar
• Kato R, Takayanaghi M. Differences among the action of phenobarbital, methylcholanthrene and male sex hormone of microsomal drug-metabolizing enzyme systems of rat liver. Jpn J Pharmacol 1966; 16: 380–390
   PubMedGoogle Scholar
• Abbritti G, De Matteis F. Decreased levels of cyto-chrome P-450 and catalase in hepatic porphyria caused by substituted acetamides and barbiturates. Importance of the allyl group in the molecule of the active drugs. Chem-Biol Interact 1972; 4: 281–286
   PubMed Web of Science ®Google Scholar
• Omura T, Sato R. The carbonmonoxide-binding pigment of liver microsomes. II. Solubilization, purification, and properties. J Biol Chem 1964; 239: 2379–2385
   PubMed Web of Science ®Google Scholar
• Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351–358
   PubMed Web of Science ®Google Scholar
• Paglia D E, Valentine W N. Studies on the quantitative and qualitative characterization of eryth-rocyte glutathione peroxidase. J Lab Clin Med 1967; 70: 158–169
   PubMed Web of Science ®Google Scholar
• Lawrence R A, Burk R F. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 1976; 71: 952–958
   PubMed Web of Science ®Google Scholar
• McCord J M, Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969; 244: 6049–6055
   PubMed Web of Science ®Google Scholar
• Burke M D, Mayer R T. Differential effects of phenobarbitone and 3-methylcholanthrene induction on the hepatic microsomal metabolism and cytochrome P-450-binding of phenoxazone and a hemologous series of its n-alkyl ethers (alkoxy-resorufins). Chem-Biol Interact 1983; 45: 243–258
   PubMed Web of Science ®Google Scholar
• Francis J E, Smith A G. Assay of mouse liver uroporphyrinogen decarboxylase by reverse-phase high-performance liquid chromatography. Anal Biochem 1984; 138: 404–410
   PubMed Web of Science ®Google Scholar
• Lowry O H, Rosebrough N J, Farr A L, Randall R J. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265–275
   PubMed Web of Science ®Google Scholar
• Smith A G, De Matteis F. Drugs and the hepatic porphyrias. Clin Haematol 1980; 9: 399–425
   PubMedGoogle Scholar
• Vizethum W, Bolsen K, Simon K, Weber K, Goerz G. Influence of chloroquine on the hexachlorobenzene-induced porphyria. Investigations in the skin, liver, and urine. Arch Dermatol Res 1980; 267: 123–130
   PubMed Web of Science ®Google Scholar
• Ferioli A, Harvey C, De Matteis F. Drug-induced accumulation of uroporphyrin in chicken hepato-cyte cultures. Structural requirements for the effect and role of exogenous iron. Biochem J 1984; 224: 769–777
   PubMed Web of Science ®Google Scholar
• Elder G H, Urquhart A J, De Salamanca R E, Munoz J J, Bonkovsky H L. Immunoreactive uroporphyrinogen decarboxylase in the liver in porphyria cutanea tarda. Lancet 1985; 2: 229–233
   PubMed Web of Science ®Google Scholar
• Debets F, Reinders J-H, Koss G, Scidel J, Strik A. Effects of dietary antioxidants on the biotransform-ation and porphyrinogenic action of hexachloro-benzene in two strains of rats. Chem-Biol Interact 1981; 37: 77–94
   PubMed Web of Science ®Google Scholar
• Cantoni L, Rizzardini M, Graziani A, Carugo C, Garattini S. Effects of chlorinated organics on intermediates in the heme pathway and on uroporphyrinogen decarboxylase. Ann NY Acad Sci 1987; 514: 128–140
   PubMed Web of Science ®Google Scholar
• Stramentinoli G, Pezzoli C, Galli-Kienle M. Protective role of S-adenosyl-L-methionine against acetaminophen induced mortality and hepato-toxicityinmice. Biochem Pharmacol 1979; 28: 3567–3571
   PubMed Web of Science ®Google Scholar
• Lieber C S, DeCarli L M, Kim C, Lowe N, Sanaki B, Leo M A. S-Adenosyl-L-methionine (SAMe) attenuates alcohol-induced mitochondrial injury in the baboon. Hepatology 1988; 8: 1412
   Web of Science ®Google Scholar
• Cantoni L, Dal Fiume D, Ruggieri R. Decarb-oxylation of uroporphyrinogen I and III in 2,3,7,8-tetrachlorodibenzo-p-dioxin induced porphyria in mice. Int J Biochem 1984; 16: 561–565
   PubMedGoogle Scholar
• Koss G, Seubert S, Seubert A, Seidel J, Koransky W, Ippen H. Studies on the toxicology of hexa-chlorobenzene. V. Different phases of porphyria during and after treatment. Arch Toxicol 1983; 52: 13–22
   PubMed Web of Science ®Google Scholar
• Smith A G, Francis J E. Investigations of rat liver uroporphyrinogen decarboxylase. Comparisons of porphyrinogens I and III as substrates and the inhibition by porphyrins. Biochem J 1981; 195: 241–250
   PubMed Web of Science ®Google Scholar
• Bonkowsky H L, Collins A, Doherty J M, Tschudy D P. The glucose effect in rat liver: Studies of delta-aminolevulinate synthase and tyrosine aminotrans-ferase. Biochim Biophys Acta 1973; 320: 561–576
   PubMedGoogle Scholar
• Gajdos A, Gajdos-Torok M. The quantitative regulation of the biosynthesis of porphyrins by intra-cellular ATP concentration. Biochem Med 1969; 2: 372–388
   Google Scholar
• Masini A, Ceccarelli-Stanzani D, Trenti T, Rocchi E, Ventura E. Structural and functional properties of rat liver mitochondria in hexachlorobenzene induced experimental porphyria. Biochem Biophys Res Commun 1984; 118: 356–363
   PubMed Web of Science ®Google Scholar
• Holmsen H, Robkin L. Hydrogen peroxide lowers ATP levels in platelets without altering adenylate energy charge and platelet function. J Biol Chem 1977; 252: 1752–1757
   PubMed Web of Science ®Google Scholar
• Sies H, Gerstenecker C, Menzel H, Flohé L. Oxidation in the NADP system and release of GSSG from hemoglobin-free perfused rat liver during peroxidatic oxidation of glutathione by hydro-peroxides. FEBS Lett 1972; 27: 171–175
   PubMed Web of Science ®Google Scholar
• Maeda N, Kon K, Sekiya M, Shiga T. Increase of ATP level in human erythrocytes induced by S-adenosyl-L-methionine. Biochem Pharmacol 1986; 35: 625–629
   PubMed Web of Science ®Google Scholar