Prostaglandins and Peptic Ulcer Therapy

References

• Konturek S J, Radecki T, Piastucki I, Drozdowicz D. Studies on the gastroprotective and ulcer healing effects of colloidal bismuth subcitrate. Digestion 1987; 37: 8–15, suppl 2
   PubMedGoogle Scholar
• Soil AH. Specific inhibition by prostaglandins E2 and I2 of histamine stimulated [14C]aminopyrine accumulation and cyclic adenosine monophosphate generation by isolated canine parietal cells. J Clin Invest 1980; 65: 1222–1229
   PubMed Web of Science ®Google Scholar
• Brand D L, Roufail W M, Thomson A BR, Tapper EJ. Misoprostol, a synthetic PGE] analog, in the treatment of duodenal ulcers. A multicentre double-blind study. Dig Dis Sci 1985; 30: 147S–158S, suppl 11
   Web of Science ®Google Scholar
• Sontag S J, Mazure P A, Pontes J F, Beker S G, Dajani EZ. Misoprostol in the treatment of Duodenal ulcer. A multicentre double blind placebo controlled study. Dig Dis Sci 1985; 30: 159S–163S, suppl 11
   Web of Science ®Google Scholar
• Bright-Asare P, Sontag S J, Gould R J, Brand D L, Roufail WM. Efficacy of misoprostol (twice daily dosage) in acute healing of duodenal ulcer: a multicentre double blind controlled trial. Dig Dis Sci 1986; 31: 63S–67S, suppl 2
   Web of Science ®Google Scholar
• Lam S K, Lau W Y, Choi T C, et al. Prostaglandin E, (misoprostol) overcomes the adverse effect of chronic cigarette smoking on duodenal ulcer healing. Dig Dis Sci 1986; 31: 68S–74S, suppl 2
   Web of Science ®Google Scholar
• Thomson A BR, Navert H, Halvorsen L, et al. Treatment of duodenal ulcer with enprostil, a prostaglandin E2 analogue. Am J Med 1986; 81: 59–63, suppl 2a
   PubMed Web of Science ®Google Scholar
• Bright-Asare P, Krejs G J, Santangelo W C, et al. Treatment of duodenal ulcer with enprostil, a prostaglandin E2 analogue. Am J Med 1986; 81: 64–68, suppl 2a
   PubMed Web of Science ®Google Scholar
• Nicholson PA. A multicenter international controlled comparison of two dosage regimens of misoprostol and cimetidine in the treatment of duodenal ulcer in outpatients. Dig Dis Sci 1985; 30: 171S–177S, suppl 11
   PubMed Web of Science ®Google Scholar
• Winters L, Wilcox R, Ligny G, et al. Comparison of enprostil and cimetidine in active duodenal ulcer disease. Summary of pooled European studies. Am J Med, 186(81)69–74, suppl 2a
   PubMedGoogle Scholar
• Lauritsen K, Laursen LS, Havelund T, Bytzer P, Svendsen LB, Rask-Madsen J. Enprostil and ranitidine in duodenal ulcer healing: double blind comparative trial. Br Med J 1986; 292: 864–866
   PubMed Web of Science ®Google Scholar
• Walt R P, Pounder R E, Hawkey C J, et al. Twenty-four hour intragastric acidity and clinical trial of bedtime enprostil 70 ug compared with ranitidine 300 mg in duodenal ulcer. Aliment Pharmacol Ther 1987; 1: 161–166
   PubMedGoogle Scholar
• Agrawal N M, Saffouri D M, Kruss D M, Callison D A, Dajani EZ. Healing of benign gastric ulcer: a placebo controlled comparison of two dosage regimens of misoprostol, a synthetic analogue of prostaglandin E1. Dig Dis Sci 1985; 30: 164S–170S, suppl 11
   PubMed Web of Science ®Google Scholar
• Navert H, Thomson A BR, Archambault A, et al. Treatment of gastric ulcer with enprostil. Am J Med 1986; 81: 75–79, suppl 2a
   PubMed Web of Science ®Google Scholar
• Rachmilewitz D, Chapman J W, Nicholson P A, et al. A multicentre international controlled comparison of two dosage regimens of misoprostol with cimetidine in treatment of gastric ulcer in outpatients. Dig Dis Sci 1986; 31: 75S–80S, suppl 2
   Web of Science ®Google Scholar
• Dammann H G, Huttemann W, Kalek H D, Rohner H G, Simon B. Comparative clinical trial of enprostil and ranitidine in the treatment of gastric ulcer. Am J Med 1986; 81: 80–84, suppl 2a
   PubMed Web of Science ®Google Scholar
• Shield MJ. Interim results of a multicentre international comparison of misoprostol and cimetidine in the treatment of outpatient gastric ulcers. Dig Dis Sci 1985; 30: 178S–184S, suppl 11
   Google Scholar
• Alquist D A, Dozois R R, Zinsmeister A R, Mala-Gelada J-R. Duodenal prostaglandin synthesis and acid load in health and in duodenal ulcer disease. Gastroenterology 1983; 85: 522–529
   PubMedGoogle Scholar
• Hawkey CJ. Synthesis of prostaglandin E2, thromboxane B2, and prostaglandin catabolism in gastritis and gastric ulcer. Gut 1986; 27: 1484–1492
   PubMedGoogle Scholar
• Schlegel W, Wenk K, Dollinger H C, Raptis S. Concentrations of prostaglandin A-, E-, and F- like substances in gastric mucosa of normal subjects and of patients with gastric diseases. Clin Sci Mol Med 1977; 52: 255–258
   PubMedGoogle Scholar
• Konturek SJ. Actions of nonsteroid anti-inflammatory compounds on gastric mucosal integrity and prostaglandin formation in healthy subjects and peptic ulcer patients. Adv Inflamm Res 1984; 6: 29–37
   Google Scholar
• Wright J P, Young G O, Klaff L J, Weerss L A, Price S K, Marks IN. Gastric mucosal prostaglandin E levels in patients with gastric ulcer disease and carcinoma. Gastroenterology 1982; 82: 263–267
   PubMed Web of Science ®Google Scholar
• Smith C L, Hillier K. Duodenal mucosa synthesis of prostaglandins in duodenal ulcer disease. Gut 1985; 26: 237–240
   PubMed Web of Science ®Google Scholar
• Hawkey C J, Simpson G, Somerville KW. Reduction by enprostil of aspirin induced blood loss from human gastric mucosa. Am J Med 1986; 81(2A)50–53
   PubMedGoogle Scholar
• Dajani E Z, Nissen CH. Gastrointestinal cyto-protective effects of misoprostol: clinical efficacy overview. Dig Dis Sci 1985; 30: 194S–200S, suppl 11
   Google Scholar
• Silverstein F E, Kinney M B, Saunders D R, Surawicz C M, Wilson R A, Silverman BA. Gastric protection by misoprostol against 1,300 mg of aspirin. An endoscopic dose response study. Am J Med 1987; 83(1A)32–36
   PubMedGoogle Scholar
• MacKerchner P A, Ivey K J, Baskin W N, Krause WJ. Protective effect of cimetidine on aspirin induced gastric mucosal damage. Ann Intern Med 1977; 87: 676–679
   PubMedGoogle Scholar
• Lanza FL. A double blind study of prophylactic effect of misoprostol on lesions of gastric and duodenal mucosa induced by oral administration of tolmetin in healthy subjects. Dig Dis Sci 1986; 31: 131S–136S, suppl 2
   PubMedGoogle Scholar
• Euler A R, Tytgat G, Berenguer T., et al. Failure of a cytoprotective dose of arbaprostit to heal acute duodenal ulcers. Gastroenterology 1987; 92: 604–607
   PubMed Web of Science ®Google Scholar
• Jones D B, Howden C W, Burget D W, Kerr G D, Hunt RH. Acid suppression in duodenal ulcer: a meta-analysis to define optimal dosing with antisecretory drugs. Gut 1987; 28: 1120–1127
   PubMed Web of Science ®Google Scholar
• Hawkey C J, Rampton DS. Prostaglandins and the gastrointestinal mucosa: are they important in its function, disease or treatment?. Gastroenterology 1985; 89: 1162–1188
   PubMed Web of Science ®Google Scholar
• Mahacai V, Walker K, Sevelius H, Thompson A BR. Antisecretory and serum gastrin lowering effect of enprostil in patients with duodenal ulcer disease. Gastroenterology 1985; 89: 555–561
   PubMedGoogle Scholar
• Deakin M, Ramage J, Paul A, Gray S P, Billings J, Williams JG. Effect of enprostil, a synthetic prostaglandin E2 on 24 hour intragastric acidity, nocturnal acid and pepsin secretion. Gut 1986; 27: 1054–1057
   PubMedGoogle Scholar
• Sontag S J, Graham D Y, Belsito A, et al. Cimetidine, cigarette smoking and recurrence of duodenal ulcer. N Engl J Med 1984; 311: 689–693
   PubMed Web of Science ®Google Scholar
• Korman M G, Hansky J, Eaves E R, Schmidt GT. Influence of cigarette smoking on healing and relapse in duodenal ulcer disease. Gastroenterology 1983; 85: 871–874
   PubMed Web of Science ®Google Scholar
• Massarrat S, Enschai F, Pittner PM. Increased gastric secretory capacity in smokers without gastrointestinal lesions. Gut 1986; 27: 433–439
   PubMedGoogle Scholar
• Muller-Lissner S A, Fraass C. Bile reflux is increased in cigarette smokers. Gastroenterology 1986; 90: 1295–1209
   Google Scholar
• Quimby G F, Bonnice C A, Burnstein S H, Eastwood GL. Active smoking depresses prostaglandin synthesis in human gastric mucosa. Ann Intern Med 1986; 104: 616–619
   PubMed Web of Science ®Google Scholar
• Lam SK. Prostaglandins smoking and duodenal ulcers [Letter]. Lancet 1987; 1: 212–213
   PubMedGoogle Scholar
• Vantrappen G, Jansens J, Popiela T, et al. Effect of 15(R)-15-methyl prostaglandin E2 (arbaprostil) on the healing of duodenal ulcer. A double-blind multi-center study. Gastroenterology 1982; 83: 357–363
   PubMed Web of Science ®Google Scholar
• Lam S K, Hui W M, Lau W Y, et al. Sucralfate overcomes adverse effect of cigarette smoking on duodenal ulcer healing and prolongs subsequent remission. Gastroenterology 1987; 92: 1193–1201
   PubMed Web of Science ®Google Scholar
• Konturek S J, Kwiecien N, Obtulowicz W, Kopp B, Oleksy J. Double blind controlled study of the effect of sucralfate on gastric prostaglandin formation and microbleeding in normal and aspirin treated man. Gut 1986; 27: 1450–1456
   PubMed Web of Science ®Google Scholar
• Shea-Donohue T, Steel L, Montcalm E, Dubois A. Gastric protection by sucralfate. Role of mucus and prostaglandins. Gastroenterology 1986; 91: 660–666
   PubMed Web of Science ®Google Scholar
• Somerville K W, Faulkner G, Langman M JS. Nonsteroidal anti-inflammatory drugs and bleeding peptic ulcer. Lancet 1986; 1: 462–464
   PubMed Web of Science ®Google Scholar
• Armstrong C P, Blower AL. Non-steroidal antiinflammatory drugs and life threatening complications of peptic ulceration. Gut 1987; 28: 527–532
   PubMed Web of Science ®Google Scholar
• Inman WHW. Non-steroidal anti-inflammatory drugs. PEM News 1984; 2: 4–10
   Google Scholar
• Jick S S, Perera D R, Walker A M, Jick H. Nonsteroidal anti-inflammatory drugs and hospital admissions for perforated peptic ulcer. Lancet 1987; 2: 380–382
   PubMed Web of Science ®Google Scholar
• Lanza F L, Aspinall R L, Swabb E A, Davis R E, Rack M F, Rubin A. A double blind placebo controlled endoscopic comparison of the cytoprotective effects of misoprostol and cimetidine on tolmetin induced gastric mucosal injury. Gastroenterology 1987; 92: 1491
   Google Scholar
• Agrawal N M, Tulane U, Roth S, et al. Misoprostol coadministration heals aspirin-induced gastric lesions in rheumatoid arthritis patients. Gastroenterology 1987; 92: 1290
   Google Scholar
• Redfern I S, Lee E, Feldman M. Effect of indo-methacin on gastric mucosal prostaglandins in humans. Gastroenterology 1987; 92: 969–977
   PubMed Web of Science ®Google Scholar
• Ehsanullah R SB, Page M C, Tildedley G, Wood JR. Prevention of gastroduodenal damage induced by non-steroidal anti-inflammatory drugs: controlled trial of ranitidine. Br Med J 1988; 297: 1017–1021
   PubMed Web of Science ®Google Scholar
• Graham D Y, Agrawal N M, Roth SH. Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double blind, placebo-controlled trial. Lancet 1988; 2: 1277–1280
   PubMed Web of Science ®Google Scholar
• Anonymous. Misoprostol: ulcer prophylaxis at what cost?. Lancet 1988; 2: 1293–1294
   PubMedGoogle Scholar