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Original Article

Role of Cholecystokinin in the Regulation of Pancreatic Enzyme Secretion in the Rat

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Pages 99-105 | Published online: 08 Jul 2009

References

  • Bayliss W M, Starling EH. On the causation of the so called 'peripheral reflex secretion' of the pancreas. Proc Roy Soc London 1902; 69: 352–353
  • Pavlov IP. The work of the digestive glands. Griffin, London 1902
  • Byrnes D J, Henderson L, Borody T, Rehfeld JF. Radioimmunoassay of cholecystokinin in human plasma. Clin Chim Acta 1981; 111: 81–89
  • Schafmayer A, Werner M, Becker HD. Radio-immunological determination of cholecystokinin in tissue extracts. Digestion 1982; 24: 146–154
  • Jansen J BMJ, Lamers C BHW. Radioimmunoassay of cholecystokinin in human tissue and plasma. Clin Chim Acta 1983; 131: 305–316
  • Fried G M, Ogden W D, Swierczek J, et al. Release of cholecystokinin in conscious dogs: correlation with simultaneous measurements of gallbladder pressure and pancreatic protein secretion. Gastroenterology 1983; 85: 1113–1119
  • Cantor P. Evaluation of radioimmunoassay for cholecystokinin in human plasma. Scand J Clin Lab Invest 1986; 46: 213–221
  • Yamamura T, Takahashi T, Kusonoki M, Kantoh M, Seino Y, Utsonomiya J. Gallbladder dynamics and plasma cholecystokinin responses after meals, oral water, or sham feeding in healthy subjects. Am J Med Sci 1988; 295: 102–107
  • Makovec F, Bani M, Cereda R, et al. Pharmacological properties of lorglumide as a member of a new class of cholecystokinin antagonists. Drug Res 1987; 37: 1265–1268
  • Makovec F, Chiste R, Bani M, Pacini M A, Setnikar I, Rovati LA. New glutamaric acid derivatives with potent competitive and specific cholecysto-kinin-antagonistic activity. Drug Res 1985; 35: 1048–1051
  • Grossman MI. Pancreatic secretion in the rat. Am J Physiol 1958; 194: 535–539
  • Hotz J, Zwicker M., Minne H., Ziegler R. Pancreatic enzyme secretion in the conscious rat. Pfluegers Arch 1975; 353: 171–189
  • Petersen H, Grossman MI. Pancreatic exocrine secretion in anesthetized and conscious rats. Am J Physiol 1977; 233: E530–E536
  • De Smul A, de Waele B, Wissocq P, Kiekens R. Exogenous and endogenous secretin stimulation in the conscious rat. Digestion 1974; 11: 39–50
  • Shaw H M, Heat T. The significance of hormones, bile salts and feeding in the regulation of bile and other digestive secretions in the rat. Aust J Biol Sci 1972; 25: 147–154
  • Shaw H M, Heat T J, Stark AE. Basal and postprandial secretion in rats. Q J Exp Physiol 1973; 58: 335–343
  • Booth A N, Robbins D J, Ribelin WE, Deeds F. Effect of raw soybean meal and amino acids on pancreatic hypertrophy in rats. Proc Soc Exp Biol Med 1960; 104: 681–683
  • Lyman RL. The effect of raw soybean meal and trypsin inhibitor diets on the intestinal and pancreatic nitrogen in the rat. J Nutr 1957; 62: 285–294
  • Lyman R L, Lepkovsky S. The effect of raw soybean meal and trypsin inhibitor diets on pancreatic enzyme secretion in the rat. J Nutr 1957; 62: 265–284
  • Green G M, Lyman RL. Feedback regulation of pancreatic enzyme secretion as a mechanism for trypsin inhibitor-induced hypersecretion in rats. Proc Soc Exp Biol Med 1972; 140: 6–12
  • Miyasaka K, Green GM. Effect of partial exclusion of pancreatic juice on rat basal pancreatic secretion. Gastroenterology 1984; 86: 114–119
  • Chernick S S, Lepkovsky S, Chaikoff IL. A dietary factor regulating the enzyme content of the pancreas: changes induced in size and proteolytic activity of the chick pancreas by ingestion of raw soybean meal. Am J Physiol 1948; 155: 33–41
  • Corring T. Mechanisme de la secretion pan-creatique exocrine chez le pore: regulation par retro inhibition. Ann Biol Anim Biochem Biophys 1973; 13: 755–756
  • Slaff J, Jacobson D, Tillman C R, Currington C, Taskes P. Protease-specific suppression of pancreatic exocrine secretion. Gastroenterology 1984; 87: 44–52
  • Owyang C, Louie D S, Tatum D. Feedback regulation of pancreatic enzyme secretion: suppression of cholecystokinin release by trypsin. J Clin Invest 1986; 77: 2042–2047
  • Heatley NG. The assay of pancreozymin and of secretin and pancreozymin simultaneously in the rat. J Endocrinol 1968; 42: 549–557
  • Dockray GJ. The action of secretin, cholecysto-kinin-pancreozymin and caerulein on pancreatic secretion in the rat. J Physiol 1972; 225: 679–692
  • Shiratori K, Chen Y F, Chey W Y, Lee K Y, Chang TM. Mechanism of increased exocrine pancreatic secretion in pancreatic juice-diverted rats. Gastroenterology 1986; 91: 1171–1178
  • Louie D S, Miller D MP, Owyang C. Cholecystokinin mediates feedback regulation of pancreatic enzyme secretion in rats. Am J Physiol 1986; 250: G252–G259
  • Fölsch U R, Cantor P, Wilms H M, Schafmayer, Becker HD, Creutzfeldt W. Role of cholecystokinin in the negative feedback control of pancreatic enzyme secretion in conscious rats. Gastroenterology 1987; 92: 449–458
  • Fôzzo R S, Stark H A, Pellechia C, Praissman M, Rosenblatt M. Effects of acute and chronic diversion of pancreatic duct secretions on plasma cholecystokinin levels in rat. Biochem Arch 1989; 5: 177–184
  • Louie DS., Liang JP, Owyang C. Characterization of a new CCK antagonist L364,718 in vitro and in vivo studies. Am J Physiol 1988; 255: G261–G266
  • Jensen R T, Zhou Z C, Murphy R B, et al. Structural features of various proglumide-related cholecystokinin receptor antagonists. Am J Physiol 1986; 251: G839–G845
  • Pap A, Lechene P, Sarles H. Exogenous and endogenous stimulations during different phases of pancreatic secretion in conscious rats. Pfluegers Arch 1979; 383: 19–27
  • Jansen J BMJ, de Jong A JL, Lamers C BHW. The cholecystokinin receptor antagonist CR1409 increases plasma cholecystokinin in rats. Regul peptides 1989; 24: 209–213
  • Niederau C, Niederau M, Strohmeyer G, Grendell JH. In vivo effects of a new potent CCK receptor antagonist on pancreatic secretion in the rat. Dig Dis Sci 1986; 31: 1144
  • Lu L, Louie D, Owyang C. A cholecystokinin releasing peptide mediates feedback regulation of pancreatic secretion. Am J Physiol 1989; 256: G430–G435
  • Miyasaka K, Guan D, Liddle RA, Green GM. Feedback regulation by trypsin: evidence for intraluminal CCK-reieasing peptide. Am J Physiol 1989; 257: G175–G181
  • Sun G, Lee K Y, Chang T M, Chey WY. Effect of pancreatic juice diversion on secretin release in rats. Gastroenterology 1989; 96: 1173–1179
  • Hadorn B, Hess J, Troesch V, Verhaage W, Gotze H, Bender SW. Role of bile acids in the activation of trypsinogen by enterokinase: disturbance of trypsinogen activation in patients with intrahepatic biliary atresia. Gastroenterology 1974; 66: 548–555
  • Elmslie R. The effect of bile on the activation of trypsinogen and the activity of trypsin in pancreatic juice. Br J Surg 1965; 52: 465–470
  • Green G M, Nasset ES. Effect of bile duct obstruction on pancreatic enzyme secretion and intestinal proteolytic enzyme activity in the rat. Am J Dig Dis 1977; 22: 437–434
  • Green GM, Nasset ES. Importance of bile in regulation of intraluminal enzyme activities in the rat. Gastroenterology 1980; 79: 695–702
  • Miyasaka K, Kitani K. A difference in stimulatory effects on pancreatic exocrine secretion between ursodeoxycholate and trypsin inhibitor in the rat. DigDisSci 1986; 31: 978–986
  • Baba N, Suzuki T, Tobe T, et al. Influence of obstructive jaundice on pancreatic growth and on basal levels of cholecystokinin and gastrin in rats. DigDisSci 1986; 31: 1233–1241
  • Meyer JH. Control of pancreatic exocrine secretion. Physiology of the gastrointestinal tract, LR Johnson. Raven Press, New York 1981; 43–55
  • de Jong A JL, Jansen J BMJ, Hafkenscheid J CM, Lamers C BHW. Role of cholecystokinin in bombesin-stimulated pancreatic enzyme secretion in conscious rats. Pancreas 1990; 5: 194–199
  • Green G M, Olds B A, Matthews G, Lyman RL. Protein as a regulator of pancreatic enzyme secretion in the rat. Proc Soc Exp Biol Med 1973; 142: 1162–1167
  • Green G M, Nasset ES. Role of dietary protein in rat pancreatic enzyme secretory response to a meal. J Nutr 1983; 113: 2245–2252
  • Laugier R, Sarles H. Action of oleic acid on the exocrine pancreatic secretion of the conscious rat: evidence for an anti-cholecystokinin-pancreozymin factor. J. Physiol 1977; 271: 81–92
  • Demol P, Sarles H. Action of fatty acids on the exocrine secretion of the conscious rat: further evidence for a protein pancreatic inhibitory factor. J Physiol. 1978; 275: 27–37
  • Liddle R A, Green G M, Conrad C K, Williams JA. Proteins but not amino acids, carbohydrates, or fats stimulate cholecystokinin secretion in the rat. Am J Physiol 1986; 251: G243–G248
  • Liddle R A, Goldfine JD, Williams JA. Bioassay of plasma cholecystokinin in rats: effects of food, trypsin inhibitor, and alcohol. Gastroenterologv 1984; 87: 542–549
  • Green G M, Miyasaka K. Rat pancreatic response to intestinal infusion of intact and hydrolyzed protein. Am J Physiol 1983; 245: G394–G398
  • Douglas B R, Woutersen R A, Jansen J BMJ, de Jong A JL, Lamers C BHW. The influence of different nutrients on plasma cholecystokinin levels in the rat. Experientia 1988; 44: 21–23
  • Brown M R, Allen R, Villareal J, Rivier J, Vale W. Bombesin-like activity: radioimmunologic assessment in biological tissues. Life Sci 1978; 23: 2721–2728
  • Moody T W, Pert CB. Bombesin-like peptides in rat brain: quantitation and biological characterization. Biochem Biophys Res Commun 1979; 90: 7–14
  • Dockray G J, Vaillant C, Walsh JH. The neuronal origin of bombesin-like immunoreactivity in the rat gastrointestinal tract. Science NY 1979; 4: 1561–1568
  • Yanaihara N, Yanaihara C, Mochizuki T, Inwa K, Fujita T, Iwanaga T. Immunoreactive GRP. Peptides 1981; 2: 185–192, suppl 2
  • Knuthsen S, Hoist J J, Baldissera F GA, et al. Gastrin-releasing peptide in the porcine pancreas. Gastroenterology 1987; 92: 1153–1158
  • Moghimzadeh E, Ekman R, Hakanson R, Yanaihara N, Sundler F. Neuronal gastrin-releasing peptide in the mammalian gut and pancreas. Neuro-science 1983; 10: 553–563
  • Ghatei M A, George S K, Major JH, Carlei F, Polak JM, Bloom SR. Bombesin-like immunoreactivity in the pancreas of man and other mammalian species. Experientia 1984; 40: 884–886
  • Erspamer V, Improta G, Melchiorri P, Sopranzi N. Evidence of cholecystokinin release by bombesin in the dog. Br J Pharmacol 1974; 52: 227–232
  • De Jong A JL, Klamer M, Jansen J BMJ, Lamers C BHW. Effect of atropine and somatostatin on bombesin-stimulated plasma gastrin, cholecystokinin and pancreatic polypeptide in man. Regul Peptides 1987; 17: 285–293
  • Basso N, Giri S, Improta G, et al. External pancreatic secretion after bombesin in man. Gut 1975; 16: 994–998
  • Anderson L, Dockray GJ. The cholecystokinin antagonist L-364,718 inhibits the action of cholecystokinin but not bombesin on rat pancreatic secretion in vivo. Eur J Pharmacol 1988; 146: 307–311
  • Gardner J D, Jensen RT. Characterization of receptors for gastrointestinal peptides. Scand J Gastroenterol 1983; 18: 7–18, suppl 82
  • Damge C, Hajri A, Aprahamian M. Effects of a new potent CCK receptor antagonist on the trophic action of CCK, caerulein. bombesin and GRP on the rat exocrine pancreas. Digestion 1987; 38: 12
  • Wisner JR, Ozawa S, Renner IG. Evidence against cholecystokinin mediation of basal and bombesin-stimulated pancreatic secretion in the rat. Gastroenterology 1988; 95: 151–155
  • Herzig K H, Louie D S, Owyang C. In vivo action of bombesin on exocrine pancreatic secretion in the rat: independent of cholecystokinin and cholinergic mediation. Pancreas 1988; 3: 292–296
  • Konturek S J, Anderson PS. Effects of nonpeptidal CCK receptor antagonist (L-364,718) on exocrine pancreatic and plasma hormonal response to CCK, gastrin, bombesin, vagal-cholinergic and meal stimulation. Gastroenterology 1988; 94: A235
  • Lamers C BHW, de Jong A JL, Singer M V, Niebel W, Jansen J BMJ. Role of cholecystokinin in bombesin-stimulated gastric acid and pancreatic enzyme secretion in dogs. Gastroenterology 1988; 94: A249

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