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Original Article

Fermentation to Short-Chain Fatty Acids and Lactate in Human Faecal Batch Cultures Intra- and Inter-Individual Variations versus Variations Caused by Changes in Fermented Saccharides

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Pages 1285-1294 | Received 24 Apr 1991, Accepted 10 Jul 1991, Published online: 08 Jul 2009

References

  • Salyers A A, Kuritza A P, McCarthy R E. Influence of dietary fiber on the intestinal environment. Proc Soc Exp Biol Med 1985; 180: 415–421
  • Sahota S S, Bramley P M, Menzies I S. The fermentation of lactulose by colonic bacteria. J Gen Microbiol 1982; 128: 319–325
  • Meijer-Severs G J, van Santen E. Short-chain fatty acids and succinate in feces of healthy human volunteers and their correlation with anaerobe cultural counts. Scand J Gastroenterol 1987; 22: 672–676
  • Wolin M J, Miller T L. Carbohydrate fermentation. Human intestinal microflora in health and disease, D J Hentges. Academic Press, New York 1983; 147–165
  • Salyers A A, Leedle J Z. Carbohydrate metabolism in the human colon. Human intestinal microflora in health and disease, D J Hentges. Academic Press, New York 1983; 129–146
  • Anderson I H, Levine A S, Levitt M D. Incomplete absorption of the carbohydrate in all-purpose wheat flour. N Engl J Med 1981; 304: 891–892
  • Stephen A M, Haddad A C, Phillips S F. Passage of carbohydrate into the colon. Direct measurements in humans. Gastroenterology 1983; 85: 589–595
  • Englyst H N, Cummings J H. Digestion of the polysaccharides of some cereal foods in the human small intestine. Am J Clin Nutr 1985; 42: 778–787
  • Thornton J R, Dryden A, Kelleher J, Losowsky M S. Superefficient starch absorption. A risk factor for colonic neoplasia. Dig Dis Sci 1987; 32: 1088–1091
  • Bond J H, Levitt M D. Quantitative measurement of lactose malabsorption. Gastroenterology 1976; 70: 1058–1062
  • MacFarlane G T, Cummings J H, Allison C. Protein degradation by human intestinal bacteria. J Gen Microbiol 1986; 132: 1647–1656
  • Rasmussen H S, Holtug K, Mortensen P B. Degradation of amino acids to short-chain fatty acids in humans. Scand J Gastroenterol 1988; 23: 178–182
  • Mortensen P B, Holtug K, Bonnén H, Clausen M R. The degradation of amino acids, proteins and blood to short-chain fatty acids is prevented by lactulose. Gastroenterology 1990; 98: 353–360
  • Cummings J H, Southgate D AT, Branch W, Houston H, Jenkins D JA, James W PT. Colonic response to dietary fibre from carrot, cabbage, apple, bran, and guar gum. Lancet 1978; 1: 5–9
  • Fleming S E, Rodriquez M A. Influence of dietary fiber on fecal excretion of volatile fatty acids by human adults. J Nutr 1983; 113: 1613–1625
  • Rasmussen H S, Holtug K, Andersen J R, Krag E, Mortensen P B. The influence of ispagula husk and lactulose on the in vivo and the in vitro production capacity of short chain fatty acids in humans. Scand J Gastroenterol 1987; 22: 406–410
  • Fleming S E, Marthinsen D, Kuhnlein N. Colonic function and fermentation in men consuming high fiber diets. J Nutr 1984; 113: 2535–2544
  • Weaver G A, Krause J A, Miller T L, Wolin M J. Constancy of glucose and starch fermentations by two different human faecal microbial communities. Gut 1989; 30: 19–25
  • McBurney M I, Thompson L U. Effect of human faecal donor on in vitro fermentation variables. Scand J Gastroenterol 1989; 24: 359–367
  • Zijlstra J B, Beukema J, Wolthers B G, Byrne B M, Groen A, Donkert L. Pretreatment methods prior to gas chromatographic analysis of volatile fatty acids from faecal samples. Clin Chim Acta 1977; 78: 243–250
  • Gutmann I, Wahlefeld A W. Lactate determination with lactate dehydrogenase and NAD. Methods of enzymatic analysis, H U Bergmeyer. Academic Press, New York 1974; 1464–1468
  • Gips C H, Reitsema A, Wibbens-Albersts M. Preservation of urine for ammonia determination with a direct method. Clin Chim Acta 1970; 29: 501–505
  • Armitage P. Statistical methods in medical research. Blackwell Scientific Publications, London 1977; 4: 189–268
  • Bergman E N. Production and utilization of metabolites by the alimentary tract as measured in portal and hepatic blood. Digestion and metabolism in the ruminant, I W McDonald, A CI Warner. University of New England Publishing Unit, Bid-deford, Maine 1975; 292–319
  • Marty J F, Vernay M Y, Abravanel G M. Acetate absorption and metabolism in the rabbit hindgut. Gut 1985; 26: 562–569
  • Roediger W EW. Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut 1980; 21: 793–798
  • Cummings J H, Pomare E W, Branch W J, Nay-Lor C PE, Macfarlane G T. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 1987; 28: 1221–1227
  • Vernia P, Caprilli R, Latella G, Barbetti F, Magliocca F M, Cittadini M. Fecal lactate and ulcerative colitis. Gastroenterology 1988; 95: 1564–1568
  • Oh M S, Phelps K R, Traube M, Barbosa-Saldivar J L, Boxhill C, Carroll H J. D-Lactic acidosis in a man with the short-bowel syndrome. N Engl J Med 1979; 301: 249–252
  • Vince A, Killingley M, Wrong O M. Effect of lactulose on ammonia production in a fecal incubation system. Gastroenterology 1978; 74: 544–549
  • Salyers A A. Diet and the colonic environment: measuring the response of human colonic bacteria to changes in the host's diet. Dietary fiber: basic and clinical aspects, G V Vahouny, D Kritchevsky. Plenum Press, New York 1986; 119–130
  • Kotarski S F, Salyers A A. Effect of long generation times on growth of Bacteriodes thetaiotaomicron in carbohydrate-limited continuous culture. J Bac-teriol 1981; 146: 853–860
  • McCarthy R, Salyers A A. Isolation and characterization of outer membranes from Bacteroides thetaiotaomicron grown on different carbohydrates. J Bacterid 1984; 158: 102–109
  • Bjørneklett A, Jenssen E. Relationships between hydrogen (H2) and methane (CH4) production in man. Scand J Gastroenterol 1982; 17: 985–992
  • Bond J H, Levitt M D. Use of pulmonary hydrogen (H2) measurements to quantitate carbohydrate absorption. J Clin Invest 1972; 51: 219–225

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