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Scandinavian Journal of Gastroenterology Volume 26, 1991 - Issue 10
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Original Article

Effect of the Prostaglandin E1 Analogue Misoprostol on the Carbon Tetrachloride-Induced Injury of Rat Liver Cells in Culture

S. Bang Depts. of Pathology and Medicine, Ullevål Hospital, Oslo, Norway
,
J. Myren Depts. of Pathology and Medicine, Ullevål Hospital, Oslo, Norway
,
K. Beraki Depts. of Pathology and Medicine, Ullevål Hospital, Oslo, Norway
&
O. Næss Depts. of Pathology and Medicine, Ullevål Hospital, Oslo, Norway
Pages 1066-1068 | Received 03 Jun 1991, Accepted 17 Jun 1991, Published online: 08 Jul 2009

References

  • Silverstein F E, Kimmey M B, Saunders D R, et al. Gastric protection by misoprostol against 1300 mg of aspirin. An endoscopic study. Dig Dis Sci 1986; 31: 1375–1415
  • Myren J. Injury of liver tissue in mice after single injection of carbon tetrachloride. Acta Pathol Microbiol Scand 1956, suppl 116: 1–64
  • Ruwart M J, Rush B D, Friedle N M, Piper R C, Kolaja G J. Protective effect of 16, 16‐dimethyl PGE2 on liver and kidney. Prostaglandins 1981; 21: 97–102
  • Stachura J, Tarnawski A, Ivey K J, et al. Prosta glandin protection of carbon tetrachloride induced liver cell necrosis in rats. Gastroenterology 1981; 81: 211–217
  • Rush B, Meritt M V, Kaluzny M, van Schoick T, Brunden M N, Ruwart M. Studies on the mechanism of the protective action of 16,16‐dimethyl PGE2 in carbon tetrachloride induced acute hepatic injury in the rat. Prostaglandins 1986; 32: 439–455
  • Guarner F, Fremont‐Smith M, Corzo J, Ouiroga J, Rodriguez J L, Prieto J. In vivo and in vitro effects of arachidonic acid products on liver cell integrity following carbon tetrachloride poisoning. Adv Prostaglandin Thromboxane Leucotriene Res 1983; 12: 75–83
  • Ujhelyi E, Divald A, Vajta G, Jeney A, Lapis K. Effect of PGI2 in carbon tetrachloride induced liver injury. Acta Physiol Hung 1984; 64: 425–430
  • Divald A, Ujhelyi E, Jeney A, Lapis K, Institoris L. Hepatoprotective effects of prostacyclins on CC14‐induced liver injury in rats. Exp Mol Pathol 1985; 42: 163–166
  • Mourelle M, Amezcua J L, Hong E. Effect of rio prostil and colchine on CCl4‐acute liver damage in rats. Relationship with plasma membrane lipids. Prostaglandins 1987; 33: 859–877
  • Bang S, Myren J, Naess O, Beraki K, Serck‐Hanssen A, Arnesen K. Prostaglandins and CCl4‐induced liver cell mortality. The effect of the prostaglandin E2 analogue enprostil. Scand J Gastroenterol 1988; 23: 931–934
  • Seglen P O. Preparation of isolated rat liver cells. Methods Cell Biol 1976; 13: 29–83

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