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Original Article

Sucralfate—Safety and Side Effects

Pages 36-42 | Published online: 08 Jul 2009

References

  • Potocnik F. Aluminium and Alzheimer's disease in perspective. Geriatrics 1990; 2: 14–18
  • Alfrey A C. Aluminium intoxication. N Engl J Med 1984; 310: 1113–1115
  • Lione A. Aluminium intake from non-prescription drugs and sucralfate. Gen Pharmacol 1985; 16: 223–229
  • Martin R B. The chemistry of aluminium as related to biology and medicine. Clin Chem 1986; 32: 1797–1806
  • Giesing D H, Lanman R C, Runsen D J. Absorption of sucralfate in man [Abstract]. Gastroenterology 1982; 82: 1066A
  • Haram E M, Weberg R, Berstad A. Urinary excretion of aluminium after ingestion of sucralfate and an aluminium-containing antacid in man. Scand J Gastroenterol 1987; 22: 615–618
  • Ungethum M. Study of the influence of 1 g sucralfate administered 4 daily for 4 weeks on the aluminium, phosphate, calcium and magnesium metabolism of healthy subjects. E. Merck, Darmstad 1983, Clinical Research Report
  • Allain P, Mauras Y, Krari N, Duchier J, Cournot A, Larcheveque J. Plasma and urine aluminium concentrations in healthy subjects after administration of sucralfate. Br J Clin Pharmacol 1990; 29: 391–395
  • Mistry P, Varghese Z, Pounder R E. Plasma aluminium concentration and 24-hour urinary excretion before, during and after six weeks of treatment with sucralfate 1 g qds [Abstract]. Gut 1990; 31: A1199
  • Bolin T D, Davis A E, Duncombe V M, Billington B. Role of maintenance sucralfate in prevention of duodenal ulcer recurrence. Am J Med 1987; 83(suppl 3B)91–94
  • Paakonen M, Aukee S, Janatuinen E, et al. Sucralfate as maintenance treatment for the prevention of duodenal ulcer recurrence. Am J Med 1989; 86(suppl 6A)133–135
  • Burnatowska-Hledin M A, Mayor G H. The effects of sucralfate ingestion on serum and specific tissue aluminium concentration in normal rats. Clin Toxicol 1984; 22: 87–93
  • Bannwarth B, Gaucher A, Burnel D, Aussedat R, Pere P, Netter P J. Blood. urine and bone aluminium concentrations in patients treated with sucralfate [Abstract]. Acta Pharmacol Toxicol 1986; 59: 205
  • Yokel R A, McNamara P J. Aluminium bioavailability and disposition in adult and immature rabbits. Toxicol Appl Pharmacol 1985; 77: 344–352
  • Yokel R A, McNamara P J. Influence of renal impairment, chemical form, and serum protein binding on intravenous and oral aluminium kinetics in the rabbit. Toxicol Appl Pharmacol 1988; 95: 32–43
  • Iwamoto N, Ono T, Yamazaki S, et al. Clinical features of aluminium-associated bone disease in long-term hemodialysis patients. Nephron 1986; 42: 204–209
  • Robertson J A, Salusky L B, Goodman W G, Norris K C, Coburn J W. Sucralfate, intestinal aluminium absorption, and aluminium toxicity in a patient on dialysis. Ann Intern Med 1989; 111: 179–181
  • Withers D J, Woolf A S, Kingswood J C, Tsang W N, Mansell M A. Encephalopathy in a patient taking aluminium-containing agents. sucralfate [Letter]. Lancet 1989; 2: 674
  • Campistol J M, Cases A, Botey A, Revert A. Acute aluminium encephalopathy in an uraemic patient. Nephron 1989; 51: 103–106
  • Lederer E D, Gillum D M. Accelerated development of hypercalcaemic aluminium associated bone disease in a patient with protracted acute renal failure [Abstract]. Kidney Int 1989; 35: 378
  • Short A IK, Winney R J, Robson J S. Reversible microcytic hypochromic anaemia in dialysis patients due to aluminium intoxication. Proc Eur Dial Transplant Assoc—Eur Ren Assoc 1980; 17: 226–233
  • Alfrey A C, Le Gendre G R, Kaehny W D. The dialysis encephalopathy syndrome: possible aluminium intoxication. N Engl J Med 1976; 294: 184–188
  • Parkinson I S, Ward M K, Kerr D NS. Dialysis encephalopathy. bone disease. and anaemia: the aluminium intoxication syndrome during regular haemodialysis. J Clin Pathol 1981; 34: 1285–1294
  • Alfrey A C. Dialysis encephalopathy syndrome. Ann Rev Med 1978; 29: 93–98
  • Arieff I. Dementia, renal failure and brain aluminium. Ann Intern Med 1979; 90: 741–747
  • Candy J M, Oakley A E, Klinowski J, et al. Aluminosalicylates and senile plaque formation in Alzheimer's disease. Lancet 1986; 1: 354–357
  • Caster W O. Dietary aluminium and Alzheimer's disease: a review. Sci Total Environ 1981; 17: 31–36
  • Hughes J T. Aluminium encephalopathy and Alzheimer's disease. Lancet 1989; 1: 490–491
  • Hanslip J I, Gidden D, Boyd E JS, Marks I N, Wormsley K G. The effect of mucosal protective and antisecretory drugs on assimilation of food bound vitamin B12 [Abstract). Gut 1987; 28: A1341–A1342
  • Marks I N, Wright J P, Girdwood A H, Gilinsky N H, Lucke W. Maintenance therapy with sucralfate reduces rate of gastric ulcer recurrence. Am J Med 1985; 79(suppl 2C)32–35
  • Marks I N, Girdwood A H, Wright J P, et al. Nocturnal regimen of sucralfate in maintenance treatment of gastric ulcer. Am J Med 1987; 83(suppl 2B)95–98
  • Marks I N, Girdwood A H, Newton K A, O'Keefe S JD, Marotta F, Lucke W. A maintenance regimen of sucralfate 2 g at night for reduced relapse rate in duodenal ulcer disease. Am J Med 1989; 86(suppl 6A)136–140
  • Marks I N, Wright J P, Denycr M, Garisch J AM, Lucke W. Comparison of sucralfate with cimetidine in short-term treatment of chronic peptic ulcer. S Afr Med J 1980; 57: 567–573
  • Chines A, Pacifici R. Antacid and sucralfateinduced hypophosphataemic osteomalacia: a case report and review of the literature. Calcif Tissue Int 1990; 47: 291–295
  • Sherman R A, Hwang E R, Walker J A, Eisinger R P. Reduction in serum phosphate due to sucralfate. Am J Gastroenterol 1983; 78: 210–211
  • Leung A CT, Henderson I S, Halls D J, Dobbie J W. Aluminium hydroxide versus sucralfate as a phosphate binder in uraemia. Br Med J 1983; 286: 1379–1381
  • Roxe D M, Mistovica M, Barch D H. Phosphate-binding effects of sucralfate in patients with chronic renal failure. Am J Kidney Dis 1989; 131: 194–199
  • Kozak E, Hudnik V, Drinovec J, . The influence of aluminium hydroxide and sucralfate on serum aluminium levels in chronic dialysis patients. Trace element—analytical chemistry in medicine and biology, P Brütter, P Schrumel, et al. Walter de Guyter, Berlin 1987; Vol. 4: 473–480
  • Vucelic B, Hadzic N, Gragas J, Puretic Z. Changes in serum phosphorus, calcium and alkaline phosphatase due to sucralfate. Int J Clin Pharmacol Ther Toxicol 1986; 24: 93–96
  • Chiverton S G, Hunt R N. Pharmacokinetics and pharmacodynamics of treatments for peptic ulcer disease in the elderly. Am J Gastroenterol 1988; 83: 211–215
  • Lacz J P, Groschang A C, Giesing D H, et al. The effect of sucralfate on drug absorption in dogs [Abstract]. Gastroenterology 1982; 82: 1108A
  • Smart H L, Somerville K W, Williams J, Richens A. Langman MJS. The effects of sucralfate upon phenytoin absorption in man. Br J Clin Pharmacol 1985; 20: 238–240
  • Nix D E, Watson W A, Hardy L, et al. The effect of sucralfate pre-treatment on the pharmacokinetics of ciprofloxacin. Pharmacotherapy 1989; 9: 377–380
  • Ryan R, Carlson J, Farris F. Effect of sucralfate in the absorption and disposition of amitriptyline in humans [Abstract 299]. Fed Proc 1986; 45: 205
  • Cantral K A, Schaaf L J, Jungnickel P W, Monsour H P. Effect of sucralfate on theophylline absorption in healthy volunteers. Clin Pharm 1988; 7: 58–61
  • Mungall D, Talbert R L, Phillips C, et al. Sucralfate and warfarin [Abstract]. Ann Intern Med 1983; 98: 557L
  • Talbert R L, Dalmady-Israel C, Bussey H I, et al. Effect of sucralfate on plasma warfarin concentration in patients requiring chronic warfarin therapy. Drug Intell Clin Pharm 1985; 19: 456–457
  • Lau A, Chang C W, Schlesinger P. Evaluation of a potential drug interaction between sucralfate and aspirin [Abstract]. Drug Intell Clin Pharm 1985; 19: 457A
  • Pugh M NC, Small R E, Garnett W R, et al. Effect of sucralfate on ibuprofen absorption in normal volunteers. Clin Pharmacokinet 1984; 3: 630–633
  • Gambertoglio J C, Romac D R, Yong C-L, Birnbaum J, Lizak P, Amend W JC. Lack of effect of sucralfate on prednisone bioavailability. Am J Gastroenterol 1987; 82: 42–45
  • Giesing D H, Lanman R C, Dimmitt D C, Runser D J. Lack of effect of sucralfate on digoxin pharmacokinetics [Abstract]. Gastroenterology 1983; 85: 116SA
  • Maconochie J G, Thomas M, Michael M F, Jenner W R, Tanner R JN. Ranitidine sucralfate interaction. Clin Pharmacol Ther 1987; 41(suppl 205)110–112A
  • Mullersman G, Gotz V P, Russell W L, Derendorf H. Lack of clinically significant in vitro and in vivo interactions between ranitidine and sucralfate. J Pharm Sci 1986; 75: 995–998
  • Ritschel W A, Banerjes P S, Koch H P, et al. Cimeti-dine-sucralfate drug interaction. Methods Find Exp Clin Pharmacol 1984; 6: 261–263
  • Lacz J, Drees D, Browne R. The effect of sucralfate on the absorption of cimetidine and other drugs in dogs [Abstract]. Am J Gastroenterol 1982; 77: 689A

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