Reactive Oxygen Metabolites and Colitis; A Disturbed Balance between Damage and Protection: A Selective Review

Reference

• Elson C O, Kagnoff M F, Fiocchi C, Befus A D, Targan S. Intestinal immunity and inflammation: recent progress. Gastroenterology 1986; 91: 746–768
   PubMed Web of Science ®Google Scholar
• Fiocchi C. Immune events associated with inflammatory bowel disease. Scand J Gastroenterol 1990; 25: 4–12, Suppl 172
   Web of Science ®Google Scholar
• McCord JM. Oxygen-derived free radicals in post-ischemic tissue injury. NEngl J Med 1985; 312: 159–163
   PubMed Web of Science ®Google Scholar
• Bulkley GB. Free radical-mediated reperfusion injury: a selective review. Br J Cancer 1987; 55: 66–73
   Google Scholar
• Flaherty J T, Weisfeldt ML. Reperfusion injury. Free Radical Biol Med 1988; 5: 409–419
   PubMed Web of Science ®Google Scholar
• Singal P K, Petkau A, Gerrard J M, Hrushovetz S, Foerster J. Free radicals in health and disease. Mol Cell Biochem 1988; 84: 121–122
   PubMed Web of Science ®Google Scholar
• Ward P A, Warren J S, Johnson KJ. Oxygen radicals, inflammation, and tissue injury. Free Radical Biol Med 1988; 5: 403–408
   PubMed Web of Science ®Google Scholar
• Farber J L, Kyle M E, Coleman JB. Biology of disease. Mechanisms of cell injury by activated oxygen species. Lab Invest 1990; 62: 670–679
   PubMed Web of Science ®Google Scholar
• Weber GF. The measurement of oxygen-derived free radicals and related substances in medicine. J Clin Chem Clin Biochem 1990; 28: 569–603
   PubMedGoogle Scholar
• Sangeetha P, Das U N, Korotkar R, Suryaprabha P. Increase in free radical generation and lipid peroxidation following chemotherapy in patients with cancer. Free Radical Biol Med 1990; 8: 15–19
   PubMed Web of Science ®Google Scholar
• Parks D A, Bulkley G B, Granger DN. Role of oxygen-derived free radicals in digestive tract diseases. Surgery 1983; 94: 415–422
   PubMed Web of Science ®Google Scholar
• Parks D A, Granger DN. Contributions of ischemia and reperfusion to mucosal lesion formation. Am J Physiol 1986; 250: G749–G753
   PubMed Web of Science ®Google Scholar
• Grisham M B, Granger DN. Neutrophil-mediated mucosal injury. Role of reactive oxygen metabolites. Dig Dis Sci 1988; 33: S–15S; 6
   Web of Science ®Google Scholar
• Koningsberger J C, Marx J JM, van Hattum J. Free radicals in gastroenterology. Scand J Gastroenterol 1988; 23: 30–40, Suppl 154
   Web of Science ®Google Scholar
• Sava P, Blondeau C, Cubertafond P, Magnin P. Radicaux libres et pathologie digestive. Gastroenterol Clin Biol 1988; 12: 214–221
   PubMedGoogle Scholar
• Douglas D M, Russel J C, Goren D, Dempsey S, Das DK. Evidence of free radical (FR) involvement in ischemic colitis. Agents Actions 1989; 27: 435–437
   PubMedGoogle Scholar
• Parks DA. Oxygen radicals: mediators of gastrointestinal pathophysiology. Gut 1989; 30: 293–298
   PubMed Web of Science ®Google Scholar
• Parks D A, Bulkley G B, Granger D N, Hamilton S R, McCord JM. Ischemic injury in the cat small intestine: role of superoxide radicals. Gastroenterology 1982; 82: 9–15
   PubMed Web of Science ®Google Scholar
• Parks D A, Granger DN. Ischemia-induced vascular changes: role of xanthine oxidase and hydroxyl radicals. Am J Physiol 1983; 245: G285–G289
   PubMed Web of Science ®Google Scholar
• Grisham M B, Hernandez L A, Granger DN. Xanthine oxidase and neutrophil infiltration in intestinal ischemia. Am J Physiol 1986; 251: G567–G574
   PubMed Web of Science ®Google Scholar
• Shandall A AW, Illiams GT, Hallett M B, Young HL. Colonic healing: a role for polymorphonuclear leucocytes and oxygen radical production. Br J Surg 1986; 73: 225–228
   PubMed Web of Science ®Google Scholar
• Clark D A, Fornabaio D M, McNeill H, Mullane K M, Caravella S J, Miller JS. Contribution of oxygen-derived free radicals to experimental necrotizing enterocolitis. Am J Pathol 1988; 130: 537–542
   PubMed Web of Science ®Google Scholar
• Miller M JS, McNeil H, Mullane K M, Caravella S J, Clark DA. SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis. Am J Physiol 1988; 255: G556–G565
   Google Scholar
• Cueva J P, Hsueh W. Role of oxygen derived free radicals in platelet activating factor induced bowel necrosis. Gut 1988; 29: 1207–1212
   PubMed Web of Science ®Google Scholar
• von Ritter C, Grisham M B, Hollwarth M, Inauen W, Granger DN. Neutrophil-derived oxidants mediate formyl-methionyl-leucyl-phenylalanine-induced increases in mucosal permeability in rats. Gastroenterology 1989; 97: 778–780
   PubMed Web of Science ®Google Scholar
• Keshavarzian A, Morgan G, Sedghi S, Gordon J H, Doria M. Role of reactive oxygen metabolites in experimental colitis. Gut 1990; 31: 786–790
   PubMed Web of Science ®Google Scholar
• Granger D N, McCord J M, Parks D A, Hollwarth ME. Xanthine oxidase inhibitors attenuate ischemia-induced vascular permeability changes in the cat intestine. Gastroenterology 1986; 90: 80–84
   PubMed Web of Science ®Google Scholar
• von Ritter C, Grisham M B, Granger DN. Sulfasalazine metabolites and dapsone attenuate formylmethionyl-leucyl-phenylalanine-induced mucosal injury in rat ileum. Gastroenterology 1989; 96: 811–816
   PubMed Web of Science ®Google Scholar
• Axelsson L G, Ahlstedt S. Characteristics of immune-complex-induced chronic experimental colitis in rats with a therapeutic effect of sulphasalazine. Scand J Gastroenterol 1990; 25: 203–209
   PubMed Web of Science ®Google Scholar
• Fitzpatrick L R, Bostwick J S, Renzetti M, Pendleton R G, Decktor DL. Antiinflammatory effects of various drugs on acetic acid induced colitis in the rat. Agents Actions 1990; 30: 393–402
   PubMedGoogle Scholar
• Craven P A, Pfanstiel J, Satto R, DeRubertis FR. Actions of sulfasalazine and 5-aminosalicylic acid as reactive oxygen scavengers in the suppression of bile acid-induced increases in colonic epithelial cell loss and proliferative activity. Gastroenterology 1987; 92: 1998–2008
   PubMed Web of Science ®Google Scholar
• Tanner A R, Arthur M JP, Wright R. Macrophage activation, chronic inflammation and gastrointestinal disease. Gut 1984; 25: 760–783
   PubMed Web of Science ®Google Scholar
• Hermanowicz A, Gibson P R, Jewell DP. The role of phagocytes in inflammatory bowel disease. Clin Sci 1985; 69: 241–249
   PubMed Web of Science ®Google Scholar
• Haagen Nielsen O. In vitro studies on the significance of arachidonate metabolism and other oxidative processes in the inflammatory response of human neutrophils and macrophages. With special reference to chronic inflammatory bowel disease. Scand J Gastroenterol 1988; 23: 1–22, Suppl 150
   PubMed Web of Science ®Google Scholar
• Verspaget H W, Mieremet-Ooms M AC, Weterman I T, Pea AS. Partial defect of neutrophil oxidative metabolism in Crohn's disease. Gut 1984; 25: 849–853
   PubMed Web of Science ®Google Scholar
• Faden H, Rossi TM. Chemiluminescent response of neutrophils from patients with inflammatory bowel disease. Dig Dis Sci 1985; 30: 139–142
   PubMed Web of Science ®Google Scholar
• Okabe N, Kuroiwa A, Fujita K, Shibuya T, Yao T, Okumura M. Immunological studies on Crohn's disease. VI. Increased chemüuminescent response of peripheral blood monocytes. J Clin Lab Immunol 1986; 21: 11–15
   PubMedGoogle Scholar
• Verspaget H W, Elmgreen J, Weterman I T, Pea A S, Riis P, Lamers C BHW. Impaired activation of the neutrophil oxidative metabolism in chronic inflammatory bowel disease. Scand J Gastroenterol 1986; 21: 1124–1130
   PubMed Web of Science ®Google Scholar
• Suematsu M, Suzuki M, Kitahora T, et al. Increased respiratory burst of leukocytes in inflammatory bowel diseases—the analysis of free radical generation by using chemiluminescence probe. J Clin Lab Immunol 1987; 24: 125–128
   PubMedGoogle Scholar
• Kitahora T, Suzuki K, Asakura H, et al. Active oxygen species generated by monocytes and polymorphonuclear cells in Crohn's disease. Dig Dis Sci 1988; 33: 951–955
   PubMed Web of Science ®Google Scholar
• Shiratora Y, Aoki S, Takada H, et al. Oxygen-derived free radical generating capacity of polymorphonuclear cells in patients with ulcerative colitis. Digestion 1989; 44: 163–171
   PubMed Web of Science ®Google Scholar
• Kelleher D, Feighery C, Weir DG. Chemiluminescence by polymorphonuclear leucocyte sub-populations in chronic inflammatory bowel disease. Digestion 1990; 45: 158–165
   PubMed Web of Science ®Google Scholar
• Williams J G, Hughes L E, Hallett MB. Toxic oxygen metabolite production by circulating phagocytic cells in inflammatory bowel disease. Gut 1990; 31: 187–193
   PubMed Web of Science ®Google Scholar
• Molin L, Stendahl O. The effect of sulfasalazine and its active components on human polymorphonuclear leukocyte function in relation to ulcerative colitis. Acta Med Scand 1979; 206: 451–457
   PubMedGoogle Scholar
• Stenson W F, Mehta J, Spilberg I. Sulfasalazine inhibition of binding of n-formyl-methionyl-leucylphenylalanine (FMLP) to its receptor on human neutrophils. Biochem Pharmacol 1984; 33: 407–412
   PubMed Web of Science ®Google Scholar
• Betts W H, Whitehouse M W, Cleland L G, Vernon-Roberts B. In vitro antioxidant properties of potential biotransformation products of salicylate, sulphasalazine and amidopyrine. Free Radical Biol Med 1985; 1: 273–280
   Google Scholar
• Ahnfelt-Rønne I, Haagen Nielsen O. The antiinflammatory moiety of sulfasalazine, 5-aminosalicylic acid, is a radical scavenger. Agents Actions 1987; 21: 191–194
   PubMedGoogle Scholar
• Ol Aruoma, Wasil M, Halliwell B, Hoey B, Butler J. The scavenging of oxidants by sulphasalazine and its metabolites. A possible contribution to their antiinflammatory effects? Biochem Pharmacol 1987; 36: 3739–3742
   Google Scholar
• Dull B J, Salata K, van Langenhove A, Goldman P. 5-Aminosalicylate: oxidation by activated leukocytes and protection of cultured cells from oxidative damage. Biochem Pharmacol 1987; 36: 2467–2472
   PubMed Web of Science ®Google Scholar
• Miyachi Y, Yoshioka A, Imamura S, Y Niwa. Effect of sulphasalazine and its metabolites on the generation of reactive oxygen species. Gut 1987; 28: 190–195
   PubMed Web of Science ®Google Scholar
• Neal T M, Winterbourn C C, Vissers M CM. Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine en olsalazine. Biochem Pharmacol 1987; 36: 2765–2768
   PubMed Web of Science ®Google Scholar
• Suematsu M, Suzuki M, Miura S, et al. Sulfasalazine and its metabolites attenuate respiratory burst of leukocytes—a possible mechanism of antiinflammatory effects. J Clin Lab Immunol 1987; 23: 31–33
   PubMedGoogle Scholar
• Carlin G, Djursäter R, Smedegård G. Inhibitory effects of sulfasalazine and related compounds on superoxide production by human polymorphonuclear leukocytes. Pharmacol Toxicol 1989; 65: 121–127
   PubMedGoogle Scholar
• Williams J G, Hallett MB. The reaction of 5-aminosalicylic acid with hypochlorite. Implication for its mode of action in inflammatory bowel disease. Biochem Pharmacol 1989; 38: 149–154
   PubMed Web of Science ®Google Scholar
• Williams J G, Hallett MB. Effect of sulphasalazine and its active metabolite, 5-amino-salicylic acid, on toxic oxygen metabolite production by neutrophils. Gut 1989; 30: 1581–1587
   PubMed Web of Science ®Google Scholar
• Wu F CW, Aitken R J, Ferguson A. Inflammatory bowel disease and male infertility: effects of sulfasalazine and 5-aminosalicylic acid on sperm-fertilizing capacity and reactive oxygen species generation. Fertil Steril 1989; 52: 842–845
   PubMedGoogle Scholar
• Ahnfelt-Rønne I, Haagen Nielsen O, Christensen A, Langholz E, Binder V, Riis P. Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid. Gastroenterology 1990; 98: 1162–1169
   PubMed Web of Science ®Google Scholar
• Dallegri F, Ottonello L, Ballestrero A, Bogliolo F, Ferrando F, Patrone F. Cytoprotection against neutrophil derived hypochlorous acid: a potential mechanism for the therapeutic action of 5-amino-salicylic acid in ulcerative colitis. Gut 1990; 31: 184–186
   PubMed Web of Science ®Google Scholar
• Gionchetti P, Guarnieri C, Campieri M, et al. Scavenger effect of sulfasalazine, 5-aminosalicylic acid, and olsalazine on superoxide radical generation. Dig Dis Sci 1991; 36: 174–178
   PubMed Web of Science ®Google Scholar
• Verspaget H W, Aparicio-Pagés M N, Verver S, et al. Influence of sulphasalazine and mesalazine on cellular and biochemical oxygen metabolite production. Effect of in vivo administration and an in vitro analysis. Scand J Gastroenterol 1991; 26: 779–786
   PubMed Web of Science ®Google Scholar
• Verspaget H, Beeken W. Mononuclear phagocytes in the gastrointestinal tract. Acta Chir Scand 1985; 113–126, Suppl 525
   Google Scholar
• Mahida Y R, Wu K C, Jewell DP. Respiratory burst activity of intestinal macrophages in normal and inflammatory bowel disease. Gut 1989; 30: 1362–1370
   PubMed Web of Science ®Google Scholar
• Simmonds N J, Allen R E, Stevens T RJ, van Someren R NM, Blake D R, Ramptom DS. Colorectal mucosa in inflammatory bowel disease produces reactive oxygen metabolites, principally hypochlorite. Gut 1991; 32: A589
   Web of Science ®Google Scholar
• Wakefield A J, Dhillon A P, Rowles P M, et al. Pathogenesis of Crohn's disease: multifocal gastrointestinal infarction. Lancet 1989; 2: 1057–1062
   PubMed Web of Science ®Google Scholar
• Wakefield A J, Sankey E A, Dhillon A P, et al. Granulomatous vasculitis in Crohn's disease. Gastroenterology 1991; 100: 1279–1287
   PubMed Web of Science ®Google Scholar
• Sawyerr A M, Wakefield A J, Rowles P, et al. Microvascular changes in Crohn's disease and ulcerative colitis: examination by vascular and scanning electron microscopy. Gut 1990; 31: A623
   Web of Science ®Google Scholar
• Verspaget H W, Pea A S, Weterman I T, Lamers C BHW. Diminished neutrophil function in Crohn's disease and ulcerative colitis identified by decreased oxidative metabolism and low superoxide dismutase content. Gut 1988; 29: 223–228
   PubMed Web of Science ®Google Scholar
• Mulder T PJ, Verspaget H W, Janssens A R, de Bruin P AF, Pea A S, Lamers C BHW. Decrease in two intestinal copper/zinc containing proteins with anti-oxidant function in inflammatory bowel disease. Gut 1991, In press
   PubMed Web of Science ®Google Scholar
• Thornalley P J, Vasák M. Possible role of metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals. Biochim Biophys Acta 1985; 827: 36–44
   PubMed Web of Science ®Google Scholar
• Pippenger C E, Meng X, Stolfi V, McGonagle B, Fazio VW. Free radical scavenging enzyme activities and trace element concentrations in erythrocytes and plasma of adult patients with inflammatory bowel disease. Falk Symposium 56 1990; 33
   Google Scholar
• Niwa Y, Somiya K, Michelson A M, Puget K. Effect of liposomal-encapsulated superoxide dismutase on active oxygen-related human disorders. A preliminary study. Free Rad Res Commun 1985; 1: 137–153
   PubMedGoogle Scholar
• Emerit J, Pelletier S, Tosoni-Verlignue D, Mollet M. Phase II trial of copper zinc superoxide dismutase (CuZnSOD) in treatment of Crohn's disease. Free Radical Biol Med 1989; 76: 145–149
   Google Scholar
• Petkau A. Scientific basis for the clinical use of superoxide dismutase. Cancer Treat Rev 1986; 13: 17–44
   PubMed Web of Science ®Google Scholar
• Flohé L. Superoxide dismutase for therapeutic use: clinical experience, dead ends and hopes. Mol Cell Biochem 1988; 84: 123–131
   PubMed Web of Science ®Google Scholar
• Yim M B, Chock P B, Stadtman ER. Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide. Proc Natl Acad Sci 1990; 87: 5006–5010
   PubMed Web of Science ®Google Scholar
• Greenwald RA. Superoxide dismutase and catalase as therapeutic agents for human diseases. A critical review. Free Radical Biol Med 1990; 8: 201–209
   PubMed Web of Science ®Google Scholar