40
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Clinical Aspects of Lactose Intolerance in Children and Adults

, , &
Pages 73-80 | Published online: 08 Jul 2009

Reference

  • Henning SJ. Postnatal development: coordination of feeding, digestion, and metabolism. Am J Physiol 1981; 241: G199–G214
  • Semenza G. Anchoring and biosynthesis of stalked brush border membrane proteins: glycosidases and peptidases of enterocytes and renal tubili. Annu Rev Cell Biol 1986; 2: 255–313
  • Mobassaleh M, Montgomery R K, Biller J A, Grand RJ. Development of carbohydrate absorption in the fetus and neonate. Pediatrics 1985; 75: 160–166
  • Savilathi E, Launiala K, Kuitunen P. Congenital lactase deficiency: a clinical study on 16 patients. Arch Dis Child 1983; 58: 246–452
  • Flatz G. Genetics of lactose digestion in humans. In: Harris H, Hirschhorn K, eds. Advances in human genetics. Plenum Press, New York 1987; 1–77
  • Simoons FJ. The geographic hypothesis and lactose malabsorption. Dig Dis 1978; 23: 963–980
  • Davidson G P, Bishop R F, Townley R RW, Holmes I H, Ruck BJ. Importance of a new virus in acute sporadic enteritis in children. Lancet 1975; 1: 242–244
  • Davidson G P, Barnes GL. Structural and functional abnormalities of the small intestine in infants and young children with rotavirus enteritis. Acta Paediatr Scand 1979; 68: 181–186
  • Gudmand-Höyer E, Söeberg B. Disaccharidase activity in the small intestinal mucosa in cases with acute enteritis. Scand J Gastroenterol 1974; 9: 405–409
  • Montgomery R K, Jonas M M, Grand RJ. Intestinal disaccharidases: structure, function, and deficiency. In: Lifshitz, ed. Carbohydrate intolerance in infancy. Marcel Dekker Inc, New York 1982; 75–94
  • Palmiter RD. What regulates lactose content in milk. Nature 1969; 221: 912–914
  • Henning SJ. Functional development of the gastrointestinal tract. In: Johnson LR, ed. Physiology of the gastrointestinal tract. 2nd ed. Raven Press, New York 1987; 285–300
  • Boyle J T, Celano P, Koldovsky O. Demonstration of a difference in expression of maximal lactase and sucrase activity along the villus in the adult rat jejunum. Gastroenterology 1980; 79: 503–507
  • Dahlqvist A, Nordstrom C. The distribution of disaccharidase activities in the villi and crypts of the small intestinal mucosa. Biochim Biophys Acta 1966; 113: 624–626
  • Büller H A, Rings E HHM, Montgomery R K, Grand RJ. Suckling rat colon synthesizes and processes active lactase-phlorizin hydrolase immunologically identical to that from jejunum. Pediatr Res 1989; 26: 232–236
  • Danielsen E M, Skovbjerg H, Noren O, Sjöström H. Biosynthesis of intestinal microvillar proteins. Intracellular processing of lactase-phlorizin hydrolase. Biochem Biophys Res Commun 1984; 122: 82–90
  • Douwes A C, Oosterkamp R F, Fernandes J, Los T, Jongbloed AA. Sugar malabsorption in healthy neonates estimated by breath hydrogen. Arch Dis Child 1980; 55: 512–515
  • Phillips SF. Lactose malabsorption and gastrointestinal function; effect on gastrointestinal transit and the absorption of other nutrients. In: Paige DM, Bayless TM, eds. Lactose digestion: clinical and nutritional implications. The John Hopkins University Press, Baltimore 1982; 51–57
  • Welsh J D, Hall WH. Gastric emptying of lactose and milk in subjects with lactose malabsorption. Am J Dig 1977; 22: 1060–1063
  • Ladas S, Papanikos J, Arapakis G. Lactose malabsorption in Greek adults: correlation of small bowel transit time with the severity of lactose intolerance. Gut 1982; 23: 968–973
  • McNeil N I, Cummings J H, James W PT. Short chain fatty acid absorption by the human large intestine. Gut 1978; 19: 819–822
  • Read NW. Diarrhoea: the failure of colonic salvage. Lancet 1982; 2: 481–483
  • Solomons N W, Garcia-Ibanez R, Viteri FE. Reduced rate of breath hydrogen excretion with lactose tolerance test in young children using whole milk. Am J Clin Nutr 1979; 32: 783–786
  • Cummings JH. Fermentation in the human large intestine: evidence and implications for health. Lancet 1983; 1: 1206–1209
  • Scrimshaw N S, Behar M. Protein malnutrition in young children. Science 1961; 133: 2093–2047
  • Büller HA, Grand RJ. Lactose intolerance. Annu Rev Med 1990; 41: 141–148
  • Barr R G, Levine M D, Watkins JB. Recurrent abdominal pain of childhood due to lactose intolerance: a prospective study. N Engl J Med 1979; 300: 1449–1452
  • Barr R G, Perman J A, Schoeller D A, Watkins JB. Breath test in pediatric gastrointestinal disorders: new diagnostic opportunities. Pediatrics 1978; 62: 393–401
  • Douwes A C, Fernandes J, Degenhardt HJ. Improved accuracy of lactose tolerance test in children, using expired H2 measurement. Arch Dis Child 1978; 53: 939–942
  • Newcomer AD. Screening tests for carbohydrate malabsorption. J Pediatr Gastroenterol Nutr 1984; 3: 6–8
  • Newcomer A D, McGill D B, Thomas P J, Hofmann AF. Prospective comparison of indirect methods for detecting lactase deficiency. N Engl J Med 1975; 293: 1232–1236
  • Ostrander C R, Cohen R S, Hopper A O, Stevenson DK. Breath hydrogen analysis: a review of the methodologies and clinical applications. J Pediatr Gastroenterol Nutr 1983; 2: 525–533
  • Solomons NW. Diagnosis and screening techniques for lactose maldigestion. Advantages of the hydrogen breath test. In: Paige DM, Bayless TM, eds. Lactose digestion: clinical and nutritional implications. John Hopkins University Press, Baltimore 1981; 91–109
  • Dahlqvist A. Enzyme deficiency and malabsorption of carbohydrates. In: Sipple HL, McNutt, eds. Sugars in nutrition. Academic Press, New York 1974; 187–214
  • Bayless T M, Rosensweig NS. A racial difference in the incidence of lactase deficiency: a survey of milk intolerance and lactase deficiency in healthy males. JAMA 1966; 197: 968–972
  • Newcomer A D, McGill DB. Distribution of disaccharidase activity in the small bowel of normal and lactase-deficient subjects. Gastroenterology 1966; 51: 481–488
  • Barr RG. Limitations of the hydrogen breath test and other techniques for predicting incomplete lactose absorption. In: Paige DM, Bayless TM, eds. Lactose digestion: clinical and nutritional implications. John Hopkins University Press, Baltimore 1981; 110–114
  • Calloway D H, Murphy E L, Bauer D. Determination of lactose intolerance by breath analysis. Am J Dig Dis 1969; 14: 811–815
  • Barr R G, Watkins J B, Perman JA. Mucosal function and breath hydrogen excretion: comparative studies in the clinical evaluation of children with nonspecific abdominal complaints. Pediatrics 1981; 68: 526–533
  • Solomons N W, Barillas C. The cut-off criterion for a positive hydrogen breath test in children: a reappraisal. J Pediatr Gastroenterol Nutr 1986; 5: 920–925
  • Maffei H VL, Metz G, Bampoe V, Shiner M, Herman S, Brook C GD. Lactose intolerance, detected by the hydrogen breath test, in infants and children with chronic diarrhoea. Arch Dis Child 1979; 766–771
  • Metz G, Blendis L M, Jenkins D JA. Hydrogen breath test for lactase deficiency. N Engl J Med 1976; 294: 730
  • Arola H, Koivula T, Jokela H, et al. Comparison of indirect diagnostic methods for hypolactasia. Scand J Gastroenterol 1988; 23: 351–357
  • Lifschitz C H, Smith E O, Garza C. Delayed complete functional lactase sufficiency in breast-fed infants. J Pediatr Gastroenterol Nutr 1983; 2: 478–482
  • MacLean W C, Fink B B, Schoeller D A, Wong W, Klein PD. Lactose assimilation by full term infants: relation of [13C] and H2 breath tests with [13C] excretion. Pediatr Res 1983; 17: 629–633
  • Dahlqvist A. Assay of intestinal disaccharidases. Anal Biochem 1968; 22: 99–107
  • Dahlqvist A. Method for assay of intestinal disaccharidases. Anal Biochem 1964; 7: 18–25
  • Welsh J D, Poley J R, Bhatia M, Stevenson DE. Intestinal disaccharidase activities in relation to age, race, and mucosal damage. Gastroenterology 1978; 75: 847–855
  • Hyams J S, Stafford R J, Grand R J, Watkins JB. Correlation of lactose breath test, intestinal morphology, and lactase activity in young children. J Pediatr 1989; 97: 609–612
  • Scrimshaw N S, Murray EB. Milk and gastrointestinal symptoms. Am J Clin Nutr 1988; 48: 1099–1104, suppl
  • Kolars J C, Levitt M D, Aouji M, Savaiano DA. Yoghurt an autodigesting source of lactose. N Engl J Med 1984; 310: 1–3
  • Newcomer A D, Park H S, O'Brien P, McGill DB. Response of patients with irritable bowel syndrome and lactase deficiency using unfermented acid-ophilus milk. Am J Clin Nutr 1983; 38: 257–263
  • Grand R J, Sutphen J L, Dietz WH. Pediatric nutrition, theory and practice. Butterworths, Boston 1987; 341–349
  • Biller J A, King S, Rosenthal A, Grand RJ. Efficacy of lactase-treated milk for lactose-intolerant pediatric patients. J Pediatr 1987; 11: 91–94
  • Moskovitz M, Curtis C, Gavaler J. Does oral enzyme replacement therapy reverse intestinal lactose malabsorption?. Am J Gastroenterol 1987; 82: 632–635
  • Rand AG. Enzyme technology and the development of lactose-hydrolyzed milk. In: Paige DM, Bayless TM, eds. Lactose digestion: clinical and nutritional implications. John Hopkins University Press, Baltimore 1981; 219–230
  • Rosada J L, Solomons N W, Lisker R, Bourges H. Enzyme replacement therapy for primary adult lactase deficiency. Gastroenterology 1984; 87: 1072–1082
  • Barillas C, Solomons NW. Effective reduction of lactose maldigestion in preschool children by direct addition of beta-galactosidases to milk at mealtime. Pediatrics 1987; 79: 766–772

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.