Effects of Acute Pancreatitis on Hepatic Secretion of Lysosomal Enzymes into Bile and Hepatic Lysosomal Fragility: Protective Effects of a New Synthetic Protease Inhibitor, ONO 3307

References

• Kubota Y. Symptoms and signs in acute pancreatitis. Pancreatic disease [in Japanese], S Naito. Dobun Shoin, TokyoJapan 1983; 608–616
   Google Scholar
• Van Gossum A, Seferian V, Rodzynek J J, Wettcndorff P, Cremer M, Delcourt A. Early detection of biliary pancreatitis. Dig Dis Sci 1984; 29: 97–101
   PubMed Web of Science ®Google Scholar
• Levitt M D, Eckfeld J. I. Diagnosis of acute pancreatitis. The exocrine pancreas, V LW Go, J D Gardner, F P Brooks, E Lebenthal, E P DiMagno, G A Scheele. Raven Press, New York 1986; 481–502
   Google Scholar
• LaRusso N F, Kost L J, Garter J A, Barham S S. Triton WR-1339, a lysosomotropic compound, is excreted into bile and alters the biliarv excretion of lysosomal enzymes and lipids. Hepatology 1982; 2: 209–215
   PubMed Web of Science ®Google Scholar
• Kagawa K, Tomizawa S. Exocytotic excretion of dextran sulphate from liver to bile. Jpn J Pharmacol 1980; 30: 101–108
   PubMedGoogle Scholar
• Sewell R B, Barham S S, Zinsmeister A R, LaRusso N F. Microtubular modulation of the biliary excretion of endogenous and exogenous constitution of hepatic lysosomes. Am J Physiol 1984; 246: G8–G16
   Google Scholar
• DeDuve C, Wattiaux R. Functions of lysosomes. Ann Physiol 1966; 28: 435–492
   Google Scholar
• Glaumann H, Ericssoin J L, Marzclla L. Mechanisms of intralysosomal degradation with special reference to autophagocytosis and hctcrophagocytosis of cell organelles. Int Rev Cytol 1981; 73: 139–182
   Google Scholar
• DeDuve C. Lysosomes revisited. Eur J Biochem 1983; 137: 391–397
   PubMedGoogle Scholar
• Brown M S, Kovanen P T, Goldstein J L. Regulation of plasma cholesterol by lipoprotein receptors. Science 1981; 212: 628–635
   PubMed Web of Science ®Google Scholar
• Brown M S, Goldstein J L. Lipoprotein receptors in the liver. Control signals for plasma cholesterol traffic. J Clin Invest 1983; 72: 743–747
   PubMed Web of Science ®Google Scholar
• Rindcrkneeht H, Renner I G, Koyama H H. Lysosomal enzymes in pure pancreatic juice from normal healthy volunteers and chronic alcoholics. Dig Dis Sci 1979; 24: 180–186
   PubMed Web of Science ®Google Scholar
• LaDue J S, Wroblewski F, Karmen A. Serum glutamic oxaloacetic transaminase activity in human acute transmural myocardial infarction. Science 1954; 120: 497–499
   PubMed Web of Science ®Google Scholar
• Fleischer S, Kervina M. Subcellular fractionation of rat liver. Methods Enzymol 1974; 31: 6–41
   PubMedGoogle Scholar
• Saluja A, Hashimoto S, Saluja M, Powers R E, Meldolesi J, Steer M L. Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis. Am J Physiol 1987; 253: G508–516
   PubMed Web of Science ®Google Scholar
• Lampel M, Kern H F. Acute interstitial pancreatitis in the rat induced by excessial doses of pancreatic secretagogue. Virchows Arch 1977; 373: 97–117
   PubMed Web of Science ®Google Scholar
• Adler G, Rohr G, Kern H F. Alteration of membrane fusion as a cause of acute pancreatitis in the rat. Dig Dis Sci 1982; 27: 993–1002
   PubMed Web of Science ®Google Scholar
• Renner I G, Wisner J R, Rinderknecht H. Protective effect of exogenous secretin on ceruletide-induced acute pancreatitis in the rat. J Clin Invest 1983; 72: 1081–1092
   PubMed Web of Science ®Google Scholar
• Saluja A, Saito S, Saluja M, et al. In-vivo rat pancreatic acinar cell function during supramaximal stimulation with caerulein. Am J Physiol 1985; 249: G702–710
   PubMed Web of Science ®Google Scholar
• Scheele G, Adler G, Kern H F. Exocytosis occurs at the lateral membrane of pancreatic acinar cells during supramaximal secretagogue stimulation. Gastroenterology 1987; 92: 345–353
   PubMed Web of Science ®Google Scholar
• Hirano T, Manabe T, Tamura K, Nonaka A, Tobe T. Response of glucagon and secretin to glucose load after partial hepatectomy in dogs. Biomedical Res 1988; 9: 93–96, Suppl 3
   Google Scholar
• Hirano T, Manabe T, Tobe T. Change of portal levels of pancreatic glucagon, its responses to glucose load, and islet A cells after partial hepatectomy in dogs. Surg Res Commun 1989; 7: 61–64
   Google Scholar
• Hirano T, Manabe T, Ando K, Yoshimura T, Tobe T. Functional changes of endocrine pancreas after partial hepatectomy in rats [in Japanese]. Jpn J Gastroenterol 1990; 87: 1034–1039
   PubMedGoogle Scholar
• Hirano T, Manabe T, Tobe T. Changes in exocrine pancreas after partial hepatectomy in rats. Med Sci Res 1989; 17: 799–800
   Google Scholar
• Hirano T, Manabe T, Yamaki K, Tobe T. Endocrine and exocrine pancreas and gut hormones in partially hepatectomized dogs. Surg Res Commun 1990; 8: 1–6
   Google Scholar
• Beck J T, Pinter E, Solymar J, McKenna R D, Ritchie A C. The role of pancreatic enzymes in the pathogenesis of acute pancreatitis. II. The fate of pancreatic proteolytic enzymes in the course of acute pancreatitis. Gastroenterology 1962; 43: 60–70
   PubMed Web of Science ®Google Scholar
• Katz W, Silverstein M, Kobold E E, Thal A P. Trypsin release, kinin production, and shock. Relationship in experimental and human pancreatitis. Arch Surg 1964; 89: 322–337
   PubMedGoogle Scholar
• Schmidt T, Creutzfeld W. The possible role of phospholipase A in the pathogenesis of acute pancreatitis. Scand J Gastroenterol 1968; 4: 39–48
   Web of Science ®Google Scholar
• Geokas M C, Murphy D R, McKenna R D. The role of elastase in acute pancreatitis. Arch Pathol 1968; 86: 117–126
   PubMedGoogle Scholar
• Matsuoka S, Futagami M, Ohno H, Imaki K, Okegawa T, Kawasaki A. Inhibitory effects of ONO 3307 on various protease and tissue thromboplastin in vitro and on experimental thrombosis in vivo. Jpn J Pharmacol 1989; 51: 455–463
   PubMedGoogle Scholar