Advanced search
Publication Cover
Scandinavian Journal of Gastroenterology Volume 27, 1992 - Issue 3
Submit an article Journal homepage
17
Views
11
CrossRef citations to date
0
Altmetric
Original Article

Double-Blind Randomized Trial of Bismuth Subsalicylate and Clindamycin for Treatment of Helicobacter pylori Infection

T. U. Westblom Dept. of Medicine, Division of Infectious Diseases, St. Louis University School of Medicine, St. Louis, Missouri, and Dept. of Pathology and Dept. of Medicine, Sections of Gastroenterology and of Infectious Diseases, Marshall University School of Medicine, Huntington, West Virginia, USA
,
E. Madan Dept. of Medicine, Division of Infectious Diseases, St. Louis University School of Medicine, St. Louis, Missouri, and Dept. of Pathology and Dept. of Medicine, Sections of Gastroenterology and of Infectious Diseases, Marshall University School of Medicine, Huntington, West Virginia, USA
,
M. A. Subik Dept. of Medicine, Division of Infectious Diseases, St. Louis University School of Medicine, St. Louis, Missouri, and Dept. of Pathology and Dept. of Medicine, Sections of Gastroenterology and of Infectious Diseases, Marshall University School of Medicine, Huntington, West Virginia, USA
,
D. E. Duriex & Dept. of Medicine, Division of Infectious Diseases, St. Louis University School of Medicine, St. Louis, Missouri, and Dept. of Pathology and Dept. of Medicine, Sections of Gastroenterology and of Infectious Diseases, Marshall University School of Medicine, Huntington, West Virginia, USA
&
B. R. Midkiff Dept. of Medicine, Division of Infectious Diseases, St. Louis University School of Medicine, St. Louis, Missouri, and Dept. of Pathology and Dept. of Medicine, Sections of Gastroenterology and of Infectious Diseases, Marshall University School of Medicine, Huntington, West Virginia, USA
Pages 249-252 | Received 12 Aug 1991, Accepted 23 Oct 1991, Published online: 08 Jul 2009

References

  • Goodwin C S, Armstrong J A, Chilvers T, et al. Transfer of Campylobacter pylori and Campylobacter mustetae to Helicobacter gen. nov. as Helicobacter pylori comb. nov. and Helicobacter mustelae comb, nov., respectively. Int J Syst Bacteriol 1989; 39: 397–405
  • Wyatt J I, Dixon M F. Chronic gastritis—a pathogenetic approach. J Pathol 1988; 154: 113–124
  • Wyatt J I, Rathbone B J, Dixon M F, Heatley R V. Campylobacter pyloridis and acid induced gastric metaplasia in the pathogenesis of duodenitis. J Clin Pathol 1987; 40: 841–848
  • Goodwin C S. Duodenal ulcer, Campylobacter pylori, and the leaking roof concept. Lancet 1988; 2: 1467–1469
  • Goodwin C S, Blake P, Blincow E. The minimum inhibitory and bactericidal concentrations of antibiotics and anti-ulcer agents against Campylobacter pyloridis. J Antimicrob Chemother 1986; 17: 309–314
  • Lambert T, Megraud F, Gerbaud G, Courvalin P. Susceptibility of Campylobacter pyloridis to 20 antimicrobial agents. Antimicrob Agents Chemother 1986; 30: 510–511
  • Westblom T U, Gudipati S, Midkiff B R. In vitro susceptibility of Helicobacter pylori to the new oral cephalosporins cefpodoxime, ceftibuten and cefixime. Eur J Clin Microbiol Infect Dis 1990; 9: 691–693
  • Axon A TR. Campylobacter pylori—therapy review. Scand J Gastroenterol 1989; 24: 35–38, Suppl 160
  • Borody T I, Cole P, Noonan S, et al. Recurrence of duodenal ulcer and Campylobacter pylori infection after eradication. Med J Aust 1989; 151: 431–435
  • Westblom T U, Duriex D E, Madan E, Belshe R B. Guinea pig model for antibiotic transport across gastric mucosa: inhibitory tissue concentrations of clindamycin against Helicobacter pylon (Campylobacter pylori) following two separate dose regimens. Antimicrob Agents Chemother 1990; 34: 25–28
  • Klempner M S, Styrt B. Alkalinization of the intralysosomal pH by clindamycin and its effect on neutrophil function. J Antimicrob Chemother 1983; 12: 39–50, Suppl C
  • Westblom T U, Midkiff B R, Madan E, Subik M A. Transportation of gastric biopsies in a triphasic Campylobacter pylori media. J Clin Gastroenterol 1989; 11: 483–484
  • Madan E, Kemp J, Westblom T U, Subik M, Sexton S, Cook J. Evaluation of staining methodologies for identifying Campylobacter pylori. Am J Clin Pathol 1988; 90: 450–453
  • Aabakken L, Larsen S, Osnes M. Visual analogue scales for endoscopic evaluation of nonsteroidal anti-inflammatory drug-induced mucosal damage in the stomach and duodenum. Scand. I Gastroenterol 1990; 25: 443–448
  • Czinn S J, Bertram T A, Murray P D, Yang P. Relationship between gastric inflammatory response and symptoms in patients infected with Helicobacter pylori. Scand J Gastroenterol 1991; 26: 33–37, Suppl 181
  • Casagrande J T, Pike M C, Smith P G. An improved approximate formula for calculating sample sizes for comparing two binomial distributions. Biometrics 1978; 34: 483–486
  • Vogt K, Hahn H. Synergism between clindamycin and colloidal bismuth subcitrate against Helicobacter (Campylobacter) pylori in vitro. Zentralbl Bakteriol 1990; 274: 246–249
  • McNulty C A, Gearty J C, Crump B, et al. Campylobacter pyloridis and associated gastritis: investigator blind, placebo controlled trial of bismuth salicylate and erythromycin ethylsuccinate. Br Med J 1986; 293: 645–649
  • Stanescu A, Malfertheiner P, Mayer D, Baczako K, Ditschuneit H. Bismuth aluminate in gastroenterology. Therapeutic effects in chronic erosive Campylobacter pylori-associated gastritis. Fortschr Med 1989; 107: 623–626
  • Dobronte Z, Lakatos F, Brittig F, et al. Has Campylobacter pylori infection any clinical relevance? Methodologic, epidemiologic and clinical studies. Orv Hetil 1989; 130: 2563–2568
  • Malfertheiner P, Stanescu A, Baczako K, Mayer D, Ditschuneit H. Efficacy of a bismuth combination preparation. Efficacy in the treatment of chronic active gastritis and non-ulcerous dyspepsia. Fortschr Med 1990; 108: 402–406
  • Glupczynski Y, Nyst J F, Burette A, Vanderlinden M P, Dcltcnrc M. Lack of antibiotic compliance in patients treated for Campylobacter pylori-associated gastritis [Abstract 76]. The Vth International Workshop on Campylobacter Infections, Mexico, 1989. Puerto Vallarta
  • Westblom T U, Duriex D E. Enhancement of antibiotic concentrations in gastric mucosa by H2 receptor antagonist: implications for treatment of Helicobacter pylori infections. Dig Dis Sci 1991; 36: 25–28
  • Axon A TR. Helicobacter pylori therapy: effect on peptic ulcer disease. J Gastroenterol Hepatol 1991; 6: 131–137
  • Unge P, Gad A, Gnarpe H, Olsson J. Does omeprazole improve antimicrobial therapy directed towards gastric Campylobacter pylori in patients with antral gastritis?. Scand J Gastroenterol 1989; 24: 49–54, Suppl 167

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.