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Original Article

Islet Amyloid Polypeptide-Producing Pancreatic Islet Cell Tumor a Clinical and Biochemical Characterization

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Pages 381-387 | Received 10 Sep 1991, Accepted 16 Dec 1991, Published online: 08 Jul 2009

References

  • Westermark P, Wernstedt C, Wilander E, Sletten K. A novel peptide in the calcitonin gene-related peptide as an amyloid fibril protein in the endocrine pancreas. Biochem Biophys Res Coramun 1986; 140: 827–31
  • Westermark P, Wernstedt C, Wilander E, Hayden D W, O'Brien T D, Johnson K H. Amyloid fibrils in human insulinoma and islet of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in hormonal islet cells. Proc Natl Acad Sci USA 1987; 84: 3881–5
  • Cooper G J, Willis A C, Clark A, Turner R C, Sim R B, Reid K B. Purification and characterization of a peptide from amyloid-rich pancreas of type 2 diabetic patients. Proc Natl Acad Sci USA 1987; 84: 8628–32
  • Lukinius A, Wilander E, Westermark G T, Engström U, Westermark P. Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets. Diabetologia 1989; 32: 240–4
  • Sanke T, Bell G I, Sample C, Rubenstein Steiner A H. An islet amyloid polypeptide is derived from an 89-amino acid precursor by proteolytic processing. J Biol Chem 1988; 263: 17243–6
  • Leighton B, Cooper G J. Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro. Nature 1988; 335: 632–5
  • Kanatsuaka A, Makino H, Ohsawa H, et al. Secretion of islet amvloid polypeptide in response to glucose. FEBS Lett 1989; 259: 199–201
  • Van Jaarsveld B C, Hackeng W HL, Nieuwenhus M G, Erkelens D W, Geerdink R A, Lips C JM. Islet-amyloid polypeptide in human plasma. Lancet 1990; 1: 60
  • MacIntyre I. Amylinamide, bone conservation and pancreatic B cells. Lancet 1989; 2: 1026–7
  • Brain S D, Wimalwansa S, Maclntyre I, Williams T J. The demonstration of vasodilator activity of pancreatic amylin amide in the rabbit. Am J Pathol 1990; 136: 487–90
  • Hunter W H, Greenwood F C. Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature 1962; 194: 495–6
  • Skogseid B, Öberg K, Benson L, et al. A standardized meal stimulation test of the endocrine pancreas for early detection of pancreatic endocrine tumors in the multiple endocrine neoplasia type 1: five years experience. J Clin Endocrinol Metab 1987; 64: 1233–40
  • Norheim I, Öberg K, Theodorsson Norheim E, et al. Malignant carcinoid tumors; an analysis of 103 patients with regard to tumor localization, hormone production and survival. Ann Surg 1987; 206: 115–25
  • Eriksson B, Arnberg H, Lindgren P G, et al. Neuroendocrine pancreatic tumours: clinical presentation, biochemical and histopathological findings in 84 patients. J Intern Med 1990; 228: 103–13
  • Lindgren P G. Ultrasonically guided punctures. A modified technique. Acta Radiol Diagn 1982; 23: 653–6
  • Puchtler H, Sweat F, Levine M. On the binding of Congo red by amyloid. J Histochem Cytochem 1962; 10: 355
  • Grimelius L, Wilander E. Silver stains in the study of endocrine cell of the gut and pancreas. Invest Cell Pathol 1980; 3: 3–12
  • Singh I. A modification of the Masson-Hamperl method for staining of argentaffin cells. Anat Anz 1964; 115: 81–2
  • Eriksson B, Arnberg H, Öberg K, et al. A polyclonal antiserum against chromogranin A and B—a new sensitive marker for neuroendocrine tumours. Acta Endocrinol (Copenh) 1990; 122: 145–55
  • Westermark P, Wilander E, Westermark G T, Johnson K H. Islet amyloid polypeptide-like immunoreactivity in the B cells of type 2 (non-insulin-dependent) diabetic and non-diabetic individuals. Diabetologia 1987; 30: 887–92
  • Nakazato M, Asai J, Kangawa K, Matsukwa S, Matsuo H. Establishment of radioimmunoassay for human islet amyloid polypeptide and its tissue content and plasma concentration. Biochem Biophys Res Commun 1989; 164: 394–9
  • Butler P C, Chou J, Carter W B, et al. Effects of meal ingestion on plasma amylin concentration in NIDDM and nondiabetic humans. Diabetes 1990; 39: 752–6
  • Hartter E, Svoboda T, Lell B, et al. Reduced islet-amyloid polypeptide in insulin-dependent diabetes mellitus. Lancet 1990; 335: 854
  • Molina J M, Cooper G JS, Leighton B, Olefsky J M. Induction of insulin resistance in vivo by amylin and calcitonin gene-related peptide. Diabetes 1990; 39: 260–4
  • Ohsawa H, Kanatsuka A, Yamaguchi T, Makimo H, Yoshida S. Islet amyloid polypeptide inhibits glucose stimulated insulin secretion from isolated pancreatic islets. Biochem Biophys Res Commun 1989; 160: 961–7
  • Cooper G JS, Dag A J, Willis A C, Roberts A N, Reid K BM, Leighton B. Amylin and the amylin gene: structure, function and relationship to islet amyloid and to diabetes mellitus. Biochem Biophys Acta 1989; 1014: 247–58
  • Johnson K H, O'Brien T D, Betsholtz C, Westermark P. Islet amyloid polypeptide and diabetes mellitus. N Engl J Med 1989; 321: 513–8
  • Nakazato M, Miyazato M, Asai J, et al. Islet amyloid polypeptide, a novel pancreatic peptide, is a circulating hormone secreted under glucose stimulation. Biochem Biophys Res Commun 1990; 169: 713–8
  • Hartter E, Svoboda T, Ludvik B, et al. Basal and stimulated plasma levels of pancreatic amylin indicate its co-secretion with insulin in humans. Diabetologia 1991; 34: 52–4
  • Eriksson B, Skogseid B, Lundvist G, Wide L, Wilander E, Öberg K. Medical treatment and longterm survival in a prospective study of 84 patients with endocrine pancreatic tumors. Cancer 1990; 9: 1883–90

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