Serum Pre-Sl and Pre-S2 Antigens as Prognostic Markers in Interferon Therapy for Chronic Hepatitis B

References

• Hoofnagle JH, Peters M, Mullen KD, et al. Randomized, controlled trial of recombinant human alpha-interferon in patients with chronic hepatitis B. Gastroenterology 1988; 95: 1318–25
   PubMed Web of Science ®Google Scholar
• Lok ASF, Lai CL, Wu PC, Leung EKY. Long-term follow-up in a randomized controlled trial of recombinant alpha-2-interferon in Chinese patients with chronic hepatitis B infection. Lancet 1988; 2: 298–302
   PubMed Web of Science ®Google Scholar
• Nishiguchi S., Kuroki T, Otani S, et al. Relationship of the effects of interferon on chronic hepatitis B and the induction of 2′,5′-oligoadenylate synthetase. Hepatology 1989; 10: 29–33
   PubMedGoogle Scholar
• Dusheiko G., Dibisceglie A, Bowyer S., et al. Recombinant leukocyte interferon treatment of chronic hepatitis B. Hepatology 1985; 5: 556–60
   PubMedGoogle Scholar
• Thung SN, Gerber MA. Hepatitis B virus and polyalbumin receptors. Progress in liver diseases, H Popper, F Schalfner. Grune and Stratton, New York 1986; Vol. VIII: 335–45
   Google Scholar
• Imai M, Yanase Y, Nojiri T, Miyakawa Y, Mayumi M. A receptor for polymerized human and chimpanzee albumins on hepatitis B virus particles co-occurring with HBeAg. Gastroenterology 1979; 76: 242–7
   PubMedGoogle Scholar
• Pontisso P, Alberti A, Bortolotti F., Realdi G. Virus-associated receptors for polymerized human serum albumin in acute and in chronic hepatitis B virus infection. Gastroenterology 1983; 84: 220–6
   PubMedGoogle Scholar
• Theilmann L, Klinkert MQ, Gmelin K, Salfelt J, Schaller H, Pfaff E. Detection of pre-Sl proteins in serum and liver of HBsAg-positive patients: a new marker for hepatitis B virus infection. Hepatology 1986; 6: 186–90
   PubMedGoogle Scholar
• Pfaff E, Klinkert M, Theilmann L, Schaller H. Characterization of large surface proteins of hepatitis B virus by antibodies to pre-S-S encoded amino acids. Virology 1986; 148: 15–22
   PubMedGoogle Scholar
• Kurai K, Lino S, Koike K, Mitamura K, Endo Y, Oka H. Serum titers of pre-S(2) antigen in patients with acute and chronic type B hepatitis: relation to serum aminotransferase activity and other hepatitis B virus markers. Hepatology 1989; 9: 175–9
   PubMed Web of Science ®Google Scholar
• Tiollais P, Pourcel C, Dejean A. The hepatitis B virus. Nature 1985; 317: 489–95
   PubMed Web of Science ®Google Scholar
• Takahashi K, Kishimoto S, Ohnuma H, et al. Polypeptides coded for by the region pre-S and gene S of hepatitis B virus DNA with the receptor for polymerized human serum albumin: expression on hepatitis B particles produced in the HBe antigen or anti-HBe phase of hepatitis B virus infection. J Immunol 1986; 136: 3467–72
   PubMedGoogle Scholar
• Okamoto H, Imai M, Usuda S, et al. Hemagglutination assay of polypeptide coded by the pre-S region of hepatitis B virus DNA with monoclonal antibody: correlation of pre-S polypeptide with the receptor for polymerized human serum albumin in serums containing hepatitis B antigens. J Immunol 1985; 134: 1212–6
   PubMedGoogle Scholar
• Hermann KH, Goldmann U, Schwaltz W, Seyffarth T, Baumgarten H, Gerlich W. Large surface proteins of hepatitis B virus containing the pre-S sequence. J Virol 1984; 52: 396–402
   PubMedGoogle Scholar
• Thung SN, Gerber MA. HBsAg-associated albumin receptors and anti-albumin antibodies in sera of patients with liver disease. Gastroenterology 1981; 80: 260–4
   PubMedGoogle Scholar
• Neurath AR, Kent SBH, Strick N, et al. Identification and chemical synthesis of a host cell receptor binding site on hepatitis B virus. Cell 1986; 46: 429–36
   PubMed Web of Science ®Google Scholar
• Haruna Y, Hayashi N, Katayama K, et al. Expression of X protein and hepatitis B virus replication in chronic hepatitis. Hepatology 1991; 13: 417–21
   PubMedGoogle Scholar
• Yuki N, Hayashi N, Katayama K, et al. Quantitative analysis of pre-Sl and pre-S2 in relation to HBsAg expression. Hepatology 1990; 11: 38–43
   PubMedGoogle Scholar
• Takai E, Machida A, Ohnuma H, et al. A solid-phase enzyme immunoassay for the determination of IgM and IgG antibodies against translation products of pre-Sl and pre-S2 regions of hepatitis B virus. J Immunol Methods 1986; 95: 23–30
   PubMedGoogle Scholar
• Machida A, Ohnuma H, Takai E, et al. A synthetic peptide coded for by the pre-S2 region of hepatitis B virus for adding immunogenicity to small spherical particles made of the product of the S gene. Mol Immunol 1987; 24: 523–9
   PubMedGoogle Scholar
• Kaplan PM, Greenman RL, Gerin JL, Purcell RH, Robinson WS. DNA polymerase associated with human hepatitis B antigen. J Virol 1973; 12: 995–1005
   PubMed Web of Science ®Google Scholar
• Hess G, Gerlich W, Gerken G, Manns M., Huetteroth TH, Meyer KH. The effect of recombinant alpha-interferon treatment on serum levels of hepatitis B virus-encoded proteins in man. Hepatology 1987; 7: 704–8
   PubMedGoogle Scholar
• Gerken G, Manns M, Hess G, Meyer KH. Virus-associated receptors for polymerized human serum albumin (RpHSA) in patients with chronic active hepatitis B treated with recombinant leukocyte A interferon. Digestion 1987; 37: 96–102
   PubMedGoogle Scholar
• Brahm J, Alexander GJM, Fagan EA, et al. Clearance of pre-S2 antigen: a marker of successful interferon therapy in hepatitis B virus infection. J Med Virol 1988; 24: 453–9
   PubMedGoogle Scholar
• Lengyel P. Mechanisms of interferon action: the 2′5′A syn-thetase-RNase L pathway. Interferon, I Gresser. Academic Press, New York 1981; Vol. 3: 77–99
   Google Scholar
• Sen GC. Biochemical pathways in interferon action. Pharmacol Ther 1984; 24: 235–57
   PubMedGoogle Scholar
• Sen GC, Herz R, Davatelis V, Pestka S. Antiviral and protein-inducing activities of recombinant human leukocyte interferons and their hybrids. J Virol 1984; 50: 445–50
   PubMedGoogle Scholar
• Yokosuka O, Omata M., Imazeki F, Okuda K, Summers J. Changes of hepatitis B virus DNA in liver and serum caused by recombinant leukocyte interferon treatment: analysis intrahepatic replicative hepatitis B virus DNA. Hepatology 1985; 5: 728–34
   PubMedGoogle Scholar
• Heron I, Hokland M, Berg K. Enhanced expression of beta-2 microglobulin and HLA antigens on human lymphoid cells by interferon. Proc Natl Acad Sci USA 1978; 75: 6215–19
   PubMed Web of Science ®Google Scholar
• Alberti A, Pontisso P, Schiavon E, et al. An antibody which precipitates Dane particles in acute hepatitis type B: relation to receptor sites which bind polymerized human serum albumin on virus particles. Hepatology 1984; 4: 220–6
   PubMedGoogle Scholar
• Budkowska A, Dubreuil P, Capel H, et al. Hepatitis B virus pre-S gene encoded antigenic specificity and anti-pre-S antibody: relationship between anti-pre-S response and recovery. Hepatology 1986; 6: 360–8
   PubMedGoogle Scholar
• Vent S, Rondanelli EG, Ranieri S, O'Brien CJ, Williams R, Eddleston AL. Prospective study of cellular immunity to hepa-titis-B-virus antigens from the early incubation phase of acute hepatitis B. Lancet 1987; 18: 119–22
   Google Scholar