References
- Powell-Tuck J, MacRae K D, Healy M JR, Lennard-Jones J E, Parkins R A. A defence of the small clinical trial: evaluation of three gastroenterological studies. Br Med J 1986; 292: 599–602
- Olaison G, Sjödahl R, Tagesson C. Glucocorticoid treatment in ileal Crohn's disease: relief of symptoms but not of endo-scopically viewed inflammation. Gut 1990; 31: 325–8
- Frazer A C, Hood C, Davies A G, et al. J Carbohydrate intolerance in ulcerative colitis. Lancet 1966; 1: 503–5
- Burke D A, Godwin P GR, Axon T R. Faecal short chain fatty acids (SFA) in ulcerative colitis (UC) and controls. Gut. 1987; 28: A1387
- Rutgeerts P, Geboes K, Peeters M, et al. Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum. Lancet 1991; 338: 771–4
- Davies P S, Rhodes J. Maintenance of remission in ulcerative colitis with sulphasalazine or a high-fibre diet: a clinical trial. Br Med J 1978; 1: 1524–5
- Ritchie J K, Wadsworth J, Lennard-Jones J E, Rogers E. Controlled multicentre therapeutic trial of an unrefined carbohydrate, fibre rich diet in Crohn's disease. Br Med J 1987; 295: 517–20
- Levenstein S, Prantera C, Luzi C, D'Ubaldi A. Low residue or normal diet in Crohn's disease: a prospective controlled study in Italian patients. Gut 1985; 26: 989–93
- Lochs H, Steinhardt H J, Klaus-Wentz B, et al. Comparison of enteral nutrition and drug treatment in active Crohn's disease: results of the European cooperative Crohn's disease study. IV. Gastroenterology 1991; 101: 881–8
- O'Morain C, Segal A W, Levi A J. Elemental diet as primary treatment of acute Crohn's disease; a controlled trial. Br Med J 1984; 288: 1859–62
- Hunt J B, Payne-James J J, Palmer K R, et al. A randomised controlled trial of elemental diet and prednisolone as primary therapy in acute exacerbations of Crohn's disease. Gastroenterology 1989; 96: A224
- Dickinson R J, Ashton M G, Axon A TR, Smith R C, Yeung C K, Hill G L. Controlled trial of intravenous hyperalimentation and total bowel rest as an adjunct to the routine therapy of acute colitis. Gastroenterology 1980; 79: 1199–204
- McLntyre P B, Powell-Tuck J, Wood S R, et al. Controlled trial of bowel rest in the treatment of severe acute colitis. Gut 1986; 27: 481–5
- Lochs H, Meryn S, Marosi L, Ferenci P, Hortnagl H. Has total bowel rest a beneficial effect in the treatment of Crohn's disease?. Clin Nutr 1983; 2: 61–4
- Greenberg G R, Fleming C R, Jeejeebhoy K N, Rosenberg I H, Sales D, Tremaine W J. Controlled trial of bowel rest and nutritional support in the management of Crohn's disease. Gut 1988; 29: 1309–15
- Rigaud D, Cerf M, Melchior J C, Sautier C, René E, Mignon M. Nutritional assistance (NA) and acute attacks of Crohn's disease (CD): efficacy of total parenteral nutrition (TPN), as compared with elemental (EEN) and polymeric (PEN) enteral nutrition. Gastroenterology 1989; 96: A416
- Giaffer M H, North G, Holdsworth C D. Controlled trial of polymeric versus elemental diet in treatment of active Crohn's disease. Lancet 1990; 1: 816–8
- Rigaud D, Cosnes J, Le Quintrec Y, René E, Gendre J P, Mignon M. Controlled trial comparing two types of enteral nutrition in treatment of active Crohn's disease: elemental v polymeric diet. Gut 1991; 32: 1492–7
- Jones V A, Dickinson R J, Workman E, Wilson A J, Freeman A H, Hunter J O. Crohn's disease: maintenance of remission by diet. Lancet 1985; 2: 177–80
- Hudson M J, Hill M J, Elliott P R, Berghouse L M, Burnham W R, Lennard-Jones J E. The microbial flora of the rectal mucosa and faeces of patients with Crohn's disease before and during antimicrobial chemotherapy. J Med Microbiol 1984; 18: 335–45
- Ursing B, Aim T, Barany F, Bergelin I, et al. A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the Cooperative Crohn's Disease Study in Sweden. Gastroenterology 1982; 83: 550–62
- Brandt L J, Bernstein L H, Boley S J, Frank M S. Metronidazole therapy for perineal Crohn's disease: a follow-up study. Gastroenterology 1982; 83: 383–7
- Chapman R W, Selby W S, Jewell D P. Controlled trial of intravenous metronidazole as an adjunct to corticosteroids in severe ulcerative colitis. Gut 1986; 27: 1210–2
- Burke D A, Axon A TR, Clayden S A, Dixon M F, Johnston D, Lacey R W. The efficacy of tobramycin in the treatment of ulcerative colitis. Aliment Pharmacol Ther 1990; 4: 123–9
- Baron J H, Connell A M, Kanaghinis T G, Lennard-Jones J E, Jones Avery F. Out-patient treatment of ulcerative colitis: comparison between three doses of oral prednisone. Br Med J 1962; 2: 441–3
- Ireland A, Rosenberg W, Jewell D P. High dose methyl-prednisolone in the treatment of active ulcerative colitis. Gut. 1988; 29: A1466
- Shaffer J A, Williams S E, Turnberg L A, Houston J B, Rowland M. Absorption of prednisolone in patients with Crohn's disease. Gut 1983; 24: 182–6
- Bello C, Goldstein F, Thornton J J. Alternate-day prednisone treatment and treatment maintenance in Crohn's disease. Am J Gastroenterol 1991; 86: 460–6
- Malchow H, Ewe K, Brandes J W, et al. European Cooperative Crohn's Disease Study (ECCDS): results of drug treatment. Gastroenterology 1984; 86: 249–66
- Brignola C, Campieri M, Farruggia P, et al. The possible utility of steroids in the prevention of relapses of Crohn's disease in remission. J Clin Gastroenterol 1988; 10: 631–4
- International Mesalazine Study Group. Coated oral 5-amino-salacylic acid versus placebo in maintaining remission of inactive Crohn's disease. Aliment Pharmacol Ther 1990; 4: 55–64
- Prantera C, Pallone F, Brunetti G, et al. Oral 5-ASA in the maintenance treatment of Crohn's disease. Results of a randomized placebo controlled trial with Asacol. Gastroenterology 1992, In press
- Hawthorne A B, Logan R FA, Hawkey C J, et al. Randomized controlled trial of azathioprine withdrawal in ulcerative colitis. Br Med J 1992; 305: 20–2
- Bukhave K, Laursen L S, Lauritsen K, et al. 5-lipoxygenase inhibition in double-blind trial with zileuton: how much is sufficient in active ulcerative colitis?. Gastroenterology 1991; 100: A200
- Stenson W F, Lauritsen K, Laursen L S, et al. A clinical trial of zileuton, a specific inhibitor of 5-lipoxygenase, in ulcerative colitis. Gastroenterology 1991; 100: A253
- Forbes A, Britton T C, House I M, Gazzard B G. Safety and efficacy of acetarsol suppositories in unresponsive proctitis. Aliment Pharmacol Ther 1989; 3: 553–6
- Ryder S D, Walker R J, Jones H, Rhodes J M. Rectal bismuth subsalicylate as therapy for ulcerative colitis. Aliment Pharmacol Ther 1990; 4: 333–8
- Björck S, Dahlstrom A, Ahlman H. Topical treatment of ulcerative proctitis with lidocaine. Scand J Gastroenterol 1989; 24: 1061–72
- Campieri M, Gionchetti P, Belluzzi A, et al. 5-aminosalicylic acid, sucralphate and placebo enemas in the treatment of distal ulcerative colitis. Gastroenterology 1988; 94: A58
- Riley S A, Gupta I, Mani V. A comparison of sucralfate and prednisolone enemas in the treatment of active distal ulcerative colitis. Scand J Gastroenterol 1989; 24: 1014–8
- Mayer L, Sachar D B. Efficacy of chloroquine in the treatment of inflammatory bowel disease. Gastroenterology 1988; 94: A293
- Grace R H, Gent A E, Hellier M D. Comparative trial of sodium cromoglycate enemas with prednisolone enemas in the treatment of ulcerative colitis. Gut 1987; 28: 88–92