7
Views
13
CrossRef citations to date
0
Altmetric
Original Article

Cyclic Adenosine Monophosphate Is the Second Messenger of Prostaglandin E2- and Vasoactive Intestinal Polypeptide-Stimulated Active Bicarbonate Secretion by Guinea-Pig Duodenum

, , , , &
Pages 153-159 | Received 11 Mar 1993, Accepted 27 Jul 1993, Published online: 08 Jul 2009

References

  • Flemström G. Gastric and duodenal mucosal bicarbonate secretion. Physiology of the gastrointestinal tract, L R. Johnson, et al. Raven Press, New York 1987
  • Isenberg J I., Selling J A., Hogan D L., Koss M A. Impaired proximal duodenal bicarbonate secretion in patients with duodenal ulcer. N Engl J Med 1987; 316: 374–9
  • Simson J NL, Merhav A, Silen W. Alkaline secretion by amphibian duodenum. III. Effects of dBcAMP, theophylline, and prostaglandins. Am J Physiol 1981; 241: G528–36
  • Flemström G, Garner A. Gastroduodenal HCO3 transport: characteristics and proposed role in acidity regulation and mucosal protection. Am J Physiol 1982; 242: G183–93
  • Flemström G, Garner A, Nylander O, Hurst B C., Heylings J R. Surface epithelial HCOf transport by mammalian duodenum in vivo. Am J Physiol 1982; 243: G348–58
  • Flemstrom G, Kivilaakso E, Briden S, Nylander O, Jestedt G. Gastroduodenal bicarbonate secretion in mucosal protection. Dig Dis Sci 1985; 30: 63–8
  • Garner A, Heylings J R., Hampson S E., Stanier A M. Identification of agonists of duodenal alkaline secretion. J Intern Med 1990; 228: 97–101, Suppl 1
  • Flemström G, Heylings J R., Garner A. Gastric and duodenal HCO3 transport in vitro: effects of hormones and local transmitters. Am J Physiol 1982; 242: G100–10
  • Odes H A., Hogan D L., Ballesteros M A., Wolosin J D., Koss M A., Isenberg J I. Human duodenal mucosal bicarbonate secretion: evidence suggesting active transport under basal and stimulated conditions. Gastroenterology 1990; 98: 867–72
  • Weiser M M. Intestinal epithelial cell surface membrane glycoprotein synthesis. J Biol Chem 1973; 248: 2536–41
  • Smith P K., Krohn R I., Hermanson G T., Mallia A K., Gartner F H., Provenzano M D., et al. Measurement of protein using bicinchoninic acid. Anal Biochem 1985; 150: 76–85
  • Schwabe R U., Ebert R, Schönhöfer P S. Sensitive determination for adenylate cyclase activity by cyclic adenosine 3′,5′-mono-phosphate protein binding assay. Arch Pharmacol 1974; 286: 83–96
  • Smedfors B, Theodorsson E, Aly A, Johansson C. Role of VIP in local control of secretion. J Intern Med 1990; 228: 133–6, Suppl 1
  • Larsson L I., Fahrenkrug J, Schaffalitzky de Muckadell O, Sund-ler F, Håkanson R, Rehfeld J F. Localization of vasoactive intestinal polypeptide (VIP) to central and peripheral neurones. Proc Natl Acad Sci USA 1976; 73: 3197–200
  • Smith G S., Warhurst G, Turnberg L A. Synthesis and degradation of prostaglandin E2 in the epithelial and subepithelial layers of the rat intestine. Biochim Biophys Acta 1987; 713: 684–7
  • Sutherland E W., Robison G A., Butcher R W. Some aspects of the biological role of adenosine 3′5′monophosphate. Circulation 1968; 37: 279–306
  • Knutson L, Knutson T W., Hogan D L., Koss M A., Isenberg J I. Acetazolamide inhibits basal as well as PGE2 and H+-stimulated human duodenal mucosal bicarbonate secretion. Gastroenterology 1992; 102: A99
  • Binder H J., Lemp G F., Gardner J D. Receptors for vasoactive intestinal peptide and secretin on small intestinal epithelial cells. Am J Physiol 1980; 238: G190–6
  • Wu-Wang C-Y, Wang S-L, Stevens B, Neu J. Localization and characterization of prostaglandin Ei receptors in rat small intestine. Prostaglandins Leukot Essent Fatty Acids 1989; 36: 129–34
  • Smith G, Warhurst G, Lees M, Turnberg L. Evidence that PGE2 stimulates intestinal epithelial cell adenylate cyclase by a receptor-mediated mechanism. Dig Dis Sci 1987; 32: 71–5
  • Reimer R, Heim H K., Muallem R, Odes H S., Sewing K-F. Effects of EP-receptor subtype specific agonists and other prostanoids on adenylate cyclase activity of duodenal epithelial cells. Prostaglandins 1992; 44: 485–93
  • Coleman R A., Kennedy I, Humphrey P PA, Bunce K, Lumley P. Prostanoids and their receptors. Comprehensive medical chemistry, C Hansch, et al. Pergamon Press, Oxford 1990; Vol. 3
  • Nakaki T, Nakadate T, Yamamoto S, Kato R. Alpha2-adre-nergic receptor in intestinal epithelial cells. Mol Pharmacol 1983; 23: 228–34
  • Dharmsathaphorn K, Harms V, Yamashiro D J., Hughes R J., Binder H J., Wright E M. Preferential binding of VIP to baso-lateral membrane of rat and rabbit enterocytes. J Clin Invest 1983; 71: 27–35
  • Murer H, Amman E, Biber J, Hopfer U. The surface membrane of the small intestinal epithelial cell. I. Localization of adenyl cyclase. Biochim Biophys Acta 1976; 433: 509–19
  • Gettys T W., Corbin J D. The protein kinase family of enzymes. Receptor phosphorylation, V K. Moudgil. CRC Press, Boca Raton, FL 1989
  • de Jonge H R. Cyclic nucleotide dependent phosphorylation of intestinal epithelium proteins. Nature 1976; 262: 590–3
  • Shaltz L J., Kimberg D V., Cattieu K A. Cyclic nucleotide-depen-dent phosphorylation of rat intestinal microvillus and baso-lateral membrane proteins by an endogenous protein kinase. Gastroenterology 1978; 75: 838–46
  • Dunk C R., Brown C DA, Turnberg L A. Simulation of C1/HCO3 exchange in rat duodenal brush border membrane vesicles by cAMP. Eur J Pharmacol 1989; 414: 701–5
  • Ong S H., Whitley T H., Stowe N W., Steiner A L. Immu-nohistochemical localization of 3′:5′-cyclic AMP and3′:5′-cyclic GMP in rat liver, intestine, and testis. Proc Natl Acad Sci USA 1975; 72: 2022–6
  • Kinne R, Shaltz L J., Kinne-Safran E. Distribution of membrane-bound cyclic AMP-dependent protein kinase in plasma membranes of the kidney cortex. J Membr Biol 1975; 24: 145–59

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.