Review: Hepatocyte Transplantation: A Potential Treatment for Acute Liver Failure

References

• Stieber A C, Iwatsuki S, Starzl T E. Orthotopic liver transplantation for fulminant and subacute hepatic failure. ASAIO Transplant 1988; 34: 959–64
   PubMedGoogle Scholar
• Starzl T E, Demetris A J, Van Thiel D. Liver transplantation. N Engl J Med 1989; 321: 1014–22
   PubMed Web of Science ®Google Scholar
• Pichlmayer R. Liver transplantation in primary hepatocellular carcinoma. J Hepatol 1993; 18: 151–3
   PubMedGoogle Scholar
• Krom R AF, Wiesner R H, Rettke S R, et al. The first 100 liver transplantations at the Mayo Clinic. Mayo Clin Proc 1989; 64: 84–94
   PubMed Web of Science ®Google Scholar
• Maddrey W C, Van Thiel D H. Liver transplantation: an overview. Hepatology 1988; 8: 948–59
   PubMed Web of Science ®Google Scholar
• Todo S, Nery J, Yanaga K, Podesta L, Gordon R D, Starzl T E. Extended preservation of liver grafts with UW solution. JAMA 1989; 261: 711–4
   PubMed Web of Science ®Google Scholar
• Shaw B W, Jr, Gordon R D, Iwatsuki S, Starzl T E. Hepatic retransplantation. Transplant Proc 1985; 17: 264–71
   PubMedGoogle Scholar
• Dummer J S, Hardy A, Poorsattar A, Ho M. Early infections in kidney, heart and liver transplant recipients on cyclosporine. Transplantation 1983; 36: 259–67
   PubMed Web of Science ®Google Scholar
• Kusne S, Dummer J S, Singh N, et al. Infections after liver transplantation. An analysis of 101 consecutive cases. Medicine (Baltimore) 1988; 67: 132–43
   PubMed Web of Science ®Google Scholar
• Paya C V, Wiesner R H, Hermans P E, et al. Risk factors for cytomegalovirus and severe bacterial infections following transplantation: a prospective multivariate time-dependent analysis. J Hepatol 1993; 18: 185–95
   PubMedGoogle Scholar
• Terpstra O T, Schalm S W, Weimar W, et al. Auxiliary partial liver transplantation for end-stage chronic liver disease. N Engl J Med 1988; 319: 1507–11
   PubMed Web of Science ®Google Scholar
• Asonuma K, Gibert J C, Stein J E, Takeda T, Vacanti J P. Quantitation of transplanted hepatic mass necessary to care the Gunn rat model of hyperbilirubinemia. J Pediatr Surg 1992; 27: 298–301
   PubMed Web of Science ®Google Scholar
• Busuttil R W, Colonna J O, II, Hiatt J R, et al. The first 100 liver transplants at UCLA. Ann Surg 1987; 206: 387–402
   PubMed Web of Science ®Google Scholar
• Van de Vyver F L, Giuliano R A, Paulus G J, et al. Hemo-perfusion-hemodialysis ineffective for paraquat removal in life-threatening poisoning?. Clin Toxicol 1985; 23: 117–31
   Web of Science ®Google Scholar
• Hughes R, Williams R. Clinical experience with charcoal and resin hemoperfusion. Semin Liver Dis 1986; 6: 164–73
   PubMed Web of Science ®Google Scholar
• O'Grady J G, Gimson A E, O'Brein C J, et al. Controlled trials of charcoal hemoperfusion and prognostic factors in fulminant hepatic failure. Gastroenterology 1988; 94: 1186–92
   PubMed Web of Science ®Google Scholar
• Hume D M, Gayle W E, Jr, Williams G M. Cro circulation of patients in hepatic coma with baboon partners having human blood. Surg Gynecol Obstet 1969; 125: 495–517
   Google Scholar
• Takahashi T, Malchesky P S, Nose Y. Artificial liver: state of the art. Dig Dis Sci 1991; 36: 1327–40
   PubMedGoogle Scholar
• Rozga J, Williams F, Ro M S, et al. Development of a bioartificial liver: properties and function of a hollow-fiber module inoculated with liver cells. Hepatology 1993; 17: 258–65
   PubMed Web of Science ®Google Scholar
• Rozga J, Holzman M D, Ro M S, et al. Development of a hybrid bioartificial liver. Ann Surg 1993; 217: 502–11
   PubMed Web of Science ®Google Scholar
• Nyberg S L, Shatford R A, Hu W S, Payne W D, Cerra F B. Hepatocyte culture systems for artificial liver support: implications for critical care medicine (bioartificial liver support). Crit Care Med 1992; 20: 1157–68
   PubMedGoogle Scholar
• Uchino J, Matsue H, Takahashi M, et al. A hybrid artificial liver system: function of cultured monolayer pig hepatocytes in plasma from hepatic failure patients. ASAIO Transplant 1991; 37: M337–8
   Google Scholar
• Chang T MS. Artificial liver support based on artificial cells with emphasis on encapsulated hepatocytes. Artif Organs 1992; 16: 71–4
   PubMedGoogle Scholar
• Kawamura K, Takahashi T, Kusumoto K, et al. The development of a new hybrid hepatic support system using frozen liver pieces (FLP). Jpn J Artif Organs 1985; 14: 253–7
   Google Scholar
• Demetriou A A, Felcher A, Moscioni A D. Hepatocyte transplantation: a potential treatment for liver disease. Dig Dis Sci 1991; 36: 1320–6
   PubMed Web of Science ®Google Scholar
• Gupta S. Hepatocyte-directed somatic gene therapy: a molecular approach for treating genetic disorders. Clinical hepatology, G L Gitnick. Mosby Year Book, Inc, Chicago 1991; Vol. 10: 61–87
   Google Scholar
• Gupta S, Chowdhury J R. Hepatocyte transplantation: back to the future. Hepatology 1992; 15: 156–62
   PubMedGoogle Scholar
• Berry M N, Friend D S. High yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study. J Cell Biol 1969; 43: 506–20
   PubMed Web of Science ®Google Scholar
• Rugstad H E, Robinson S H, Yamoni C, Tashjian A H, Jr. Transfer of bilirubin uridine-diphosphate-gucuronyltransferase to enzyme deficient rats. Science 1970; 170: 553–5
   PubMedGoogle Scholar
• Sutherland D ER, Numata M, Matas A J, Simmons R L, Najarian J S. Hepatocellular transplantation in acute liver failure. Surgery 1977; 82: 124–32
   PubMed Web of Science ®Google Scholar
• Sommer B G, Sutherland D ER, Matas A J, Simmons R, Najarian J S. Hepatocellular transplantation for the treatment of D-galactosamine-induced acute liver failure in rats. Transplant Proc 1979; 11: 578–84
   PubMed Web of Science ®Google Scholar
• Makowka L, Rotstein L E, Falk R E, Falk J A, Langer B, Nossal N A, et al. Reversal of toxic and anoxic induced hepatic failure by syngeneic, allogeneic, and xenogeneic hepatocyte transplantation. Surgery 1980; 88: 244–53
   PubMedGoogle Scholar
• Makowka L, Falk R E, Rotstein L E, Nossal N A, Langer B, Blendis L M, et al. Reversal of experimental acute liver failure. Presented at 13th Annual Scientific Meeting, Association for Academic Surgery. November, 121979
   Google Scholar
• Demetriou A A, Reisner A, Sanchez J, Levenson S M, Moscioni A D, Chowdhury J R. Transplantation of microcarrier-attached hepatocytes into 90% partially hepatectomized rats. Hepatology 1988; 8: 1006–9
   PubMed Web of Science ®Google Scholar
• Emond J, Capron-Laudereau M, Meriggi F, Bernuau J, Reynes M, Houssin R D. Extent of hepatectomy in the rat: evaluation of basal conditions and effect of therapy. Eur Surg Res 1989; 21: 251–9
   PubMedGoogle Scholar
• Wang X D, Ar'Rajab A, Ahrén B, Andersson R, Bengmark S. Improvement of the effects of intrasplenic transplantation of hepatocytes after 90% hepatectomy in the rat by cotrans-plantation with pancreatic islets. Transplantation 1991; 52: 462–6
   PubMed Web of Science ®Google Scholar
• Sandbichler P, Then P, Vogel W, et al. Hepatocellular transplantation into the lung for temporary support acute liver failure in the rat. Gastroenterology 1992; 102: 605–9
   PubMedGoogle Scholar
• te Velde A A, Bosman D K, Oldenburg J, Sala M, Maas M AW, Chamuleau R AFM. Three different hepatocyte transplantation techniques for enzyme deficiency disease and acute hepatic failure. Artif Organs 1992; 16: 522–6
   PubMedGoogle Scholar
• Takeshita K, Ishibashi H, Kodama M. Hepatocellular transplantation for metabolic support in experimental acute ischemic liver failure in rats. Transplant Proc 1992; 24: 3022
   PubMedGoogle Scholar
• Ribeiro J, Nordlinger B, Ballet F, et al. Intrasplenic hepatocellular transplantation corrects hepatic encephalopathy in portacaval-shunted rats. Hepatology 1992; 15: 12–8
   PubMedGoogle Scholar
• Hirai S, Kaai S, Mito M. Encapsulated hepatocyte transplantation for the treatment of D-galactosamine-induced acute hepatic failure in rats. Eur Surg Res 1993; 25: 193–202
   PubMed Web of Science ®Google Scholar
• Baumgartner D, LaPlante-O'Neil P M, Sutherland D ER, Najarian J S. Effects of intrasplenic injection of hepatocytes, hepatocyte fragments and hepatocyte culture supernatants on D-galactosamine-induced liver failure in rats. Eur Surg Res 1983; 15: 129–35
   PubMedGoogle Scholar
• ten Berg R GM, Ernst P, van Maldegem-Dronkers C, Westbroek M DL. Effect of viable isolated hepatocytes or hepatocyte fractions on survival rate following galactosamine-induced acute liver failure. Eur Surg Res 1985; 17: 109–18
   PubMedGoogle Scholar
• Hillan K J, Burt A D, George W D, Macsween R NM, Griffiths M R, Bradley J A. Intrasplenic hepatocyte transplantation in rats with experimental liver injury: morphological and morpho-metric studies. J Pathol 1989; 159: 67–73
   PubMedGoogle Scholar
• Wang X D, Andersson R, Soltesz V, Bengmark S. Bacterial translocation after major hepatectomy in patients and rats. Arch Surg 1992; 127: 1101–6
   PubMedGoogle Scholar
• Wang X D, Soltesz V, Andersson R, Bengmark S. Bacterial translocation in acute liver failure induced by ninety percent hepatectomy in the rat. Br J Surg 1993; 80: 66–71
   PubMed Web of Science ®Google Scholar
• Wang X D, Andersson R, Ding J W, Norgan L, Bengmark S. Reticuloendothelial system function following acute liver failure induced by 90% hepatectomy in the rat. HPB-Surgery 1993; 6: 151–62
   PubMedGoogle Scholar
• Wang X D, Ar'Rajab A, Andersson R, Soltesz V, Wang V, Bengmark S. The influence of experimental acute liver failure on intestinal structure in the rat. Scand J Gastroenterol 1993; 28: 31–40
   PubMed Web of Science ®Google Scholar
• Wang X D, Andersson R, Soltesz V, Wang L, Bengmark S. The effect of portal hypertension on bacterial translocation induced by major liver resection in rats. Eur J Surg 1993; 159: 173–81
   Google Scholar
• Wang X D, Andersson R, Soltesz V, Guo W, Bengmark S. Water-soluble ethylhydroxyethyl cellulose prevents bacterial translocation induced by major liver resection in the rat. Ann Surg 1993; 217: 155–67
   PubMed Web of Science ®Google Scholar
• Demetriou A A, Whiting J, Levenson S M, et al. New method of hepatocyte transplantation and extracorporeal liver support. Ann Surg 1986; 204: 259–62
   PubMed Web of Science ®Google Scholar
• Demetriou A A, Felcher A, Moscioni A D. Hepatocyte transplantation: a potential treatment for liver disease. Dig Dis Sci 1991; 36: 1320–6
   PubMed Web of Science ®Google Scholar
• Zhang H, Miescher-Clemens E, Drugas G, Lee M, Colombani P. Intrahepatic hepatocyte transplantation following subtotal hepatectomy in the recipient: a possible model in the treatment of hepatic enzyme deficiency. J Pediatric Surg 1992; 27: 312–6
   PubMedGoogle Scholar
• Groth C G, Arborgh B, Bjorken C, Sundberg B, Lundgren G. Correction of hyperbilirubinemia in the glucuronyltransferase-deficient rats by intraportal hepatocyte transplantation. Transplant Proc 1977; 9: 313–6
   PubMedGoogle Scholar
• Kirsch R E, Terblanche J. Liver injury and regeneration. Arias, Frenkei, Wilson The liver: a series of critical surveys of the international literature. Excepta Medica, Amsterdam 1982
   Google Scholar
• Starzl T E, Porter K A, Francavilla J A, Benichou J, Putnam C W. A hundred years of the hepatotrophic factors. Elsevier/Excerpta Medica/North-Holland, Amsterdam 1978
   Google Scholar
• Vroemen J PAM, Buurman W A, van der C J, Visser R, Heirwegh K PM, Kootstra G. Transplantation of isolated hepatocytes into the pancreas. Eur Surg Res 1988; 20: 1–11
   PubMedGoogle Scholar
• Printz H, Göke B, Fehmann H C, et al. Partial hepatectomy affects pancreatic size and function in rats. Pancreas 1993; 8: 233–9
   PubMedGoogle Scholar
• Wang X D, Ar'Rajab A, Ahrén B, Andersson R, Bengmark S. The effect of pancreatic islets on transplanted hepatocytes in the treatment of acute liver failure in rats. Res Exp Med 1991; 191: 429–35
   PubMedGoogle Scholar
• Then P, Sandbichler P, Erhart R, et al. Hepatocyte transplantation into the lung for treatment of acute hepatic failure in the rat. Transplant Proc 1991; 23: 892–3
   PubMedGoogle Scholar
• Selden A C, Gupta S, Johnstone R, Hodgson H F. The pulmonary vascular bed as a site for implantation of isolated liver cells in inbred rats. Transplantation 1984; 38: 81–3
   PubMedGoogle Scholar
• Wang X D, Wang Q, Soltesz V, Andersson R. Pulmonary infections of gut origin after major liver resection in rats. Eur J Surg 1993; 159: 399–404
   PubMedGoogle Scholar
• Mito M, Kusano M, Ohnishi T, Saito T, Ebata H. Hepatocellular transplantation: morphological study on hepatocytes transplanted into rat spleen. Gastroenterol Jpn 1978; 13: 480–90
   PubMedGoogle Scholar
• Mito M, Ebata H, Kusano M, Onishi T, Saito T, Sakamoto S. Morphology and function of isolated hepatocytes transplanted into rat spleen. Transplantation 1979; 28: 499–505
   PubMedGoogle Scholar
• Mito M, Ebata H, Kusano M, Onishi T, Hiratsuko M, Saito T. Studies on ectopic liver utilizing hepatocytes after transplantation into rat spleen. Transplant Proc 1979; 11: 585
   PubMedGoogle Scholar
• Ebata H, Kusano M, Ohnishi T, Saito T, Mito M. Liver regeneration utilizing isolated hepatocytes transplanted into the rat spleen. Surg Form 1978; 29: 338–40
   PubMedGoogle Scholar
• Kusano M, Mito M. Observations on the fine structure of long-survived isolated hepatocytes inoculated into rat spleen. Gastroenterology 1982; 82: 616–28
   PubMedGoogle Scholar
• Kusano M, Ebata H, Mito M. Morphological characteristics of recomposed liver sinusoids in hepatized rat spleens. Sinusoid Liver Cells 1982; 33: 117–26
   Google Scholar
• Woods R J, Fuller B J, Attenburrow V D, Nutt L H, Hobbs K EF. Functional assessment of hepatocytes after transplantation into rat spleen. Transplantation 1982; 33: 123–6
   PubMedGoogle Scholar
• Cuervas-Mons V, Cienfuegos J A, Maganto P, et al. Long-term evaluation of isolated syngeneic hepatocytes transplanted into the normal rat spleen by TC-99M-HIDA scintigraphy. Transplantation 1985; 39: 87–90
   PubMedGoogle Scholar
• Panis Y, Puts J P, Ballet F, et al. The isolated perfused spleen: an original method for studying the function of hepatocytes transplanted into the spleen. Transplantation 1990; 49: 756–9
   PubMedGoogle Scholar
• Maganto P, Traber P G, Rusnell C, Dobbins W O, III, Keren D, Gumucio J J. Long-term maintenance of the adult pattern of liver-specific expression for P-450b, P-450e, albumin and a-fetoprotein genes in intrasplenically transplanted hepatocytes. Hepatology 1990; 11: 585–92
   PubMed Web of Science ®Google Scholar
• Nordlinger B, Wang S R, Bouma M E, Verthier N, Hillan K, Delelo R, et al. Can hepatocytes proliferate when transplanted into the spleen?. Eur Surg Res 1987; 19: 381–7
   PubMed Web of Science ®Google Scholar
• Ponder K P, Gupta S, Leland F, et al. Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation. Proc Natl Acad Sci USA 1991; 88: 1217–21
   PubMed Web of Science ®Google Scholar
• Kawai Y, Price J B, Hardy M A. Reversal of liver failure in rats by ultraviolet-irradiated hepatocyte transplantation. Transplant Proc 1987; 19: 989–91
   PubMedGoogle Scholar
• Cuervas-Mons V, Cienfuegos J A, Maganto P, et al. Time-related efficacy of liver cell isografts in fulminant hepatic failure. Transplantation 1984; 38: 23–5
   PubMedGoogle Scholar
• Flye M W, Lu X S, Yu S. Reversal of ischemic liver failure by intrasplenic liver cell transplantation. J Pediatric Surg 1987; 22: 1212–5
   PubMedGoogle Scholar
• Ricordi C, Lacy P E, Callery M P, Park P W, Flye M W. Trophic factors from pancreatic islets in combined hepatocyte-islet allografts enhance hepatocellular survival. Surgery 1989; 105: 218–23
   PubMedGoogle Scholar
• Soriano H E, Gest A, Bair D, et al. Hepatocellular transplantation via the umbilical vein in fetal and newborn. Transplant Proc 1992; 24: 2964–5
   PubMedGoogle Scholar
• Silvio M D, Murase N, Rilo H L, Nussler A K, Ildstad S T, Nalesnik M A, et al. Intrathymic transplantation of hepatocytes is facilitated by the addition of pancreatic islets. Transplant Proc 1992; 24: 2987
   PubMedGoogle Scholar
• Demetriou A A, Whiting J F, Feldman D, et al. Replacement of liver function in rat by transplantation of microcarrier-attached hepatocytes. Science 1986; 233: 1190–2
   PubMed Web of Science ®Google Scholar
• Gupta S, Aragona E, Vemuru R P, Bhargava K K, Burk R D, Chowdhury J R. Permanent engraftment and function of hepatocytes delivered to the liver: implications for gene therapy and liver repopulation. Hepatology 1991; 14: 144–9
   PubMedGoogle Scholar
• Makowka L, Rotstein L E, Falk R E, et al. Allogeneic and xenogeneic hepatocyte transplantation. Transplant Proc 1981; 13: 855–9
   PubMed Web of Science ®Google Scholar
• Wang X D, Zhao X D, Andersson R. The effects of transplantation of hepatocytes cultured with insulin on acute liver failure induced by 90% hepatectomy in the rat. Eur J Surg 1994, In press
   Google Scholar
• Miura Y, Akimoto T, Kanazawa H, Yagi K. Synthesis and secretion of protein by hepatocytes entrapped within calcium alginate. Artif Organs 1986; 10: 460–5
   PubMed Web of Science ®Google Scholar
• Suchiya M T, Yoshikawa H, Itakura M, Yamashita K. Increased de novo purine synthesis by insulin through selective enzyme induction in primary cultured rat hepatocytes. Am J Physiol 1990; 258: C841–8
   Google Scholar
• Francavilla A, Starzl T E, Porter K, et al. Screening for candidate hepatic growth factors by selective portal infusion after canine Eck's fistula. Hepatology 1991; 14: 665–70
   PubMed Web of Science ®Google Scholar
• Dixit V, Darvasi R, Arthur M, Brezina M, Lewin K, Gitnick G. Restoration of liver function in Gunn rats without immunosuppression using transplanted microencapsulated hepatocytes. Hepatology 1990; 12: 1342–9
   PubMed Web of Science ®Google Scholar
• Ricordi C, Callery M P, Lacy P E, Flye M W. Pancreatic islets enhance hepatocellular survival in combined hepatocyte-islet-cell transplantation. Transplant Proc 1989; 21: 2689
   PubMedGoogle Scholar
• Ebata H, Oikawa I, Mito M. Rejection of allogeneic hepatocytes and fetal hepatic tissue transplanted into the rat spleen. Transplantation 1985; 39: 211–23
   Google Scholar
• Cuervas-Mons V, Escandon C J, Ramos J NJ, Ortiz M J, Castillo-Olivares J L, Segovia J M. Monitoring of the rejection of intra-splenic hepatocyte allografts and xenografts in the rat using Technetium 99m-imidoacetic acid scanning. Transplant Proc 1987; 19: 3850–1
   PubMedGoogle Scholar
• Brent L, Bain A G, Butler R, Horurgh T, Opera S C, Wood P J. The antigenicity of purified liver parenchyma cells. Transplant Proc 1981; 13: 860
   PubMedGoogle Scholar
• Volpes R, van den Ord J J, Desmet V J. Can hepatocytes serve as ‘activated’ immunomodulating cells in the immune response?. J Hepatol 1992; 16: 228–440
   PubMedGoogle Scholar
• Margulis M S, Erukhimov E A, Andreiman L A, et al. Hemo-perfusion through suspension of cryopreserved hepatocytes in the treatment of patients with acute liver failure. Surg Res 1990; 2: 99–102
   Google Scholar
• Mito M, Kusano M, Kawaura Y. Hepatocyte transplantation in man. Transplant Proc 1992; 24: 3052–3
   PubMed Web of Science ®Google Scholar