27
Views
9
CrossRef citations to date
0
Altmetric
Original Article

Colonic Fermentation of Complex Dietary Carbohydrates in Short-Bowel Patients: No Association with Hydrogen Excretion and Fecal and Plasma Short-Chain Fatty Acids

, &
Pages 897-904 | Received 13 Dec 1994, Accepted 11 Jan 1995, Published online: 08 Jul 2009

References

  • McNeil N I, Cummings J H, James W PT. Short-chain fatty acid absorption by the human large intestine. Gut 1978; 19: 819–22
  • Ruppin H, Bar-Meir S, Soergel K H, Wood C M, Schmidt MG. Absorption of short-chain fatty acids by the colon. Gastroenterology 1980; 78: 1500–7
  • McNeil NI. The contribution of the large intestine to energy supplies in man. Am J Clin Nutr 1984; 39: 338–42
  • Stephen A M, Haddad A C, Philips SF. Passage of carbohydrate into the colon. Direct measurement in humans. Gastroenterology 1983; 85: 589–95
  • Woolf G M, Miller C, Kurian R, Jeejeebhoy KN. Nutritional absorption in short bowel syndrome. Evaluation of fluid, calorie and divalent cation requirements. Dig Dis Sci 1987; 32: 8–15
  • Lindberg W, Natvig H, Rygh A, Svendsen K. Høyde- og vektundersøgelser hos voksne menn og kvinner. Tiddskr Nor Laegeforen 1956; 76: 361–8
  • Hylander E, Jarnum S, Keldsbo I L, Thale M. Standardized ('trifixed') diet in the study of chronic malabsorption syndromes. Scand J Gastroenterol 1978; 13: 423–31
  • Englyst H N, Cummings JH. Non-starch polysaccharides (dietary fiber) and resistant starch. Adv Exp Med Biol 1990; 270: 205–25
  • Van de Kamer J H, Huinink H TB, Weyers HA. Rapid method for determination of fat in feces. J Biol Chem 1949; 177: 347–55
  • AOAC official methods of analysis.14th ed., S Williams. AOAC Inc., Arlington (VA) 1984
  • Mortensen P B, Hove H, Clausen M R, Holtug K. Fermentation to short-chain fatty acids and lactate in human faecal batch cultures. Intra- and inter-individual variations versus variations caused by changes in fermented saccharides. Scand J Gastroenterol 1991; 26: 1285–94
  • Gips C H, Reitsema A, Wibbens-Alberts M. Preservation of urine for ammonia determination with a direct method. Clin Chem Acta 1970; 25: 501–5
  • McArthur B, Sarnaik AP. Quantification of short-chain fatty acids in plasma. 1982; 28: 1983–4
  • Clausen M R, Mortensen P B, Bendtsen F. Serum levels of short-chain fatty acids in cirrhosis and hepatic coma. Hepatology 1991; 14: 1040–5
  • Rumessen J J, Kokholm G, Gudmand-Høyer E. Methodological aspects of breath hydrogen (H2) analysis. Evaluation of a H2 monitor and interpretation of the breath H2 test. Scand J Gastroenterol 1987; 47: 555–60
  • Rumessen J J, Hamberg O, Gudman-Høyer E. Interval sampling of end-expiratory hydrogen (H2) concentration to quantify carbohydrate malabsorption by means of lactulose standards. Gut 1990; 31: 37–42
  • Bond J J, Levitt MD. Investigation of small bowel transit time in man utilising pulmonary hydrogen (H2) measurements. J Lab Clin Med 1975; 85: 546–55
  • Nordgaard I, Hansen B S, Mortensen PB. Colon as a digestive organ in short bowel patients. Lancet 1994; 343: 373–6
  • Bergman EN. Energy contribution of volatile fatty acids from the gastrointestinal tract in various species. Physiol Rev 1990; 70: 567–90
  • Nordgaard-Andersen I, Clausen M R, Mortensen PB. Short-chain fatty acids, lactate, and ammonia in ileorectal and ileal pouch contents: a model of cecal fermentation. JPEN 1993; 17: 324–31
  • Bond J H, Levitt MD. Use of pulmonary hydrogen measurements to quantify carbohydrate absorption. J Clin Invest 1972; 51: 1219–25
  • Woolf G M, Miller C, Kurian R, Jeejeebhoy KN. Diet for patients with a short bowel: high fat or high carbohydrate?. Gastroenterology 1983; 84: 823–8
  • Levitt MD. Production and excretion of hydrogen gas in man. N Engl JMed 1969; 281: 122–7
  • Bond J H, Engel R R, Levitt MD. Factors influencing pulmonary methane excretion in man. J Exp Med 1971; 133: 572–88
  • Levitt M D, Hirsch P, Fetzer S A, Sheahan M, Levine AS. H2 excretion after ingestion of complex carbohydrates. Gastroenterology 1987; 92: 383–9
  • Chapman R W, Sillary J K, Graham M M, Saunders DR. Absorption of starch by healthy ileostomates: effect of transit time and of carbohydrate load. Am J Clin Nutr 1985; 41: 1244–8
  • Hammer HF. Colonic hydrogen absorption: quantification of its effect on hydrogen accumulation caused by bacterial fermentation of carbohydrates. Gut 1993; 34: 818–22
  • Gibson G R, Cummings J H, Macfarlane G T, Allison C, Segal I, Vorster H H, et al. Alternative pathways for hydrogen disposal during fermentation in the human colon. Gut 1990; 31: 679–83
  • Bjømeklett A, Jenssen E. Relationships between hydrogen (H2) and methane (CH4) production in man. Scand J Gastroenterol 1982; 17: 985–92
  • Cloarec D, Bornet F, Gouilloud S, Barry J-L, Salim B, Galmiche JP. Breath hydrogen response to lactulose in healthy subjects: relationship to methane producing status. Gut 1990; 31: 300–4
  • Rosado J L, Lopez P, Morales M, Allen LH. Fiber digestibility and breath-hydrogen excretion in subjects consuming rural and urban mexican diets. Am J Clin Nutr 1991; 53: 55–60
  • Flourié B, Leblond A, Ch Florent, Rautureau M, Bisalli A, Rambaud J-C. Starch malabsorption and breath gas excretion in healthy humans consuming low- and high-starch diets. Gastroenterology 1988; 95: 356–63
  • Argenzio R A, Miller N, von Engelhardt W. Effect of volatile fatty acids on water and ion absorption from the goat colon. Am J Physiol 1975; 229: 997–1002
  • Roediger W EW. Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut 1980; 21: 793–8
  • Cummings J H, Pomare E W, Branch W J, Naylor C PE, Macfarlane GT. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 1987; 28: 1221–7
  • McBurney M I, Cuff D J, Thompson LU. Rates of fermentation and short chain fatty acid and gas production of six starches by human faecal microbiota. J Sci Food Agric 1990; 50: 79–88
  • Royall D, Wolever T MS, Jeejeebhoy KN. Evidence for colonic conservation of malabsorbed carbohydrate in short bowel syndrome. Am J Gastroenterol 1992; 87: 751–6
  • Pomare E W, Branch W J, Cummings JH. Carbohydrate fermentation in the human colon and its relation to acetate concentrations in venous blood. J Clin Invest 1985; 75: 1448–54
  • Kashtan H, Stem H S, Jenkins D JA, Jenkins A L, Thompson L U, Hay K, et al. Colonic fermentation and markers of colorectal-cancer risk. Am J Clin Nutr 1992; 55: 723–8
  • Sugawara M, Sato Y, Yokoyama S, Mitsuoka T. Effect of corn fiber residue supplementation on fecal properties, flora, ammonia, and bacterial enzyme activities in healthy humans. J Nutr Sci Vitaminol Tokyo 1991; 37: 109–16
  • Flick J A, Perman JA. Nonabsorbed carbohydrate: effect on fecal pH in methane-excreting and non-excreting individuals. Am J Clin Nutr 1989; 49: 1252–7
  • Flourie B, Florent C, Jouany J P, Thivent P, Etanchaud F, Rambaud J-C. Colonic metabolism of wheat starch in healthy subjects. Effects on fecal outputs and clinical symptoms. Gastroenterology 1986; 90: 111–19
  • Hove H, Mortensen PB. Colonic lactate metabolism and D-lactic acidosis. Dig Dis Sci., In press
  • Vince A, Killingley M, Wrong OM. Effect of lactulose on ammonia production in a fecal incubation system. Gastroenterology 1978; 74: 544–9
  • Vince A J, McNeil N I, Wager J D, Wrong OM. The effect of lactulose, pectin, arabinogalactan and cellulose on the production of organic acids and metabolism of ammonia by intestinal bacteria in a faecal incubation system. Br J Nutr 1990; 63: 17–26
  • Mortensen PB. The effect of oral-administered lactulose on colonic nitrogen metabolism and excretion. Hepatology 1992; 16: 1350–6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.