Impairment of Antioxidants in Colonic Epithelial Cells Isolated from Trinitrobenzene Sulphonic Acid-Induced Colitis Rats Protective Effect of Rebamipide

References

• Halliwell B. Drug antioxidant effects, a basis for drug selection?. Drugs 1991; 42: 569–605
   PubMed Web of Science ®Google Scholar
• Granger D N, Grisham M B, Hernandez L A. Reactive oxygen metabolites: mediators of cell injury in the digestive system. Viewpoints Dig Dis 1986; 18: 13–6
   Google Scholar
• Batist G, Reynaud A, Katki A G, Travis E L, Shoemaker M C, Greene R F, et al. Enzymatic defense against radiation damage in mice, effect of selenium and vitamin E depletion. Biochem Pharmacol 1986; 35: 601–6
   PubMed Web of Science ®Google Scholar
• Kondo T, Yoshida K, Urata Y, Goto S, Gasa S, Taniguchi N. γ‐Glutamylcysteine synthetase and active transport of glutathione S‐conjugate are responsive to heat shock in K562 erythroid cells. J Biol Chem 1993; 268: 20366–72
   PubMed Web of Science ®Google Scholar
• Kondo T, Tagami S, Yoshioka A, Nishimura M, Kawakami Y. Current smoking of elderly men reduces antioxidants in alveolar macrophages. Am J Respir Crit Care Med 1994; 149: 178–82
   PubMed Web of Science ®Google Scholar
• Otamiri T, Sjädahl T. Oxygen radicals: their role in selected gastrointestinal disorders. Dig Dis 1991; 9: 133–41
   PubMed Web of Science ®Google Scholar
• Grisham M, Granger D N. Neutrophil‐mediated mucosal injury, role of reactive oxygen metabolites. Dig Dis Sci 1988; 33: 6–15, Suppl
   PubMed Web of Science ®Google Scholar
• Kitahora T, Suzuki K, Asakura H, Yoshida T, Suematsu M, Watanabe M, et al. Active oxygen species generated by monocytes and polymorphonuclear cells in Crohn's disease. Dig Dis Sci 1988; 33: 951–5, Suppl
   PubMed Web of Science ®Google Scholar
• Williams J G, Hughes L E, Hallett M B. Toxic oxygen metabolite production by circulating phagocytic cells in inflammatory bowel disease. Gut 1990; 31: 187–93
   PubMed Web of Science ®Google Scholar
• Dallegri F, Ottonello L, Ballestrero A, Bogliolo F, Ferrando F, Patrone F. Cytoprotection against neutrophil derived hypochlorous acid: a potential mechanism for the therapeutic action of 5‐aminosalicylic acid in ulcerative colitis. Gut 1990; 31: 184–6
   PubMed Web of Science ®Google Scholar
• Miyachi Y, Yoshioka A, Imamura S, Niwa Y. Effect of sulphasalazine and its metabolites on the generation of reactive oxygen species. Gut 1987; 28: 190–5
   PubMed Web of Science ®Google Scholar
• Shanahan F. Pathogenesis of ulcerative colitis. Lancet 1993; 342: 407–11
   PubMed Web of Science ®Google Scholar
• Morris G P, Beck P L, Herridge M S, Depew W T, Szewczuk M R, Wallace J L. Hapten‐induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 1989; 96: 795–803
   PubMed Web of Science ®Google Scholar
• Hoshino H, Sugiyama S, Ohara A, Goto H, Tsukamoto Y, Ozawa T. Mechanism and prevention of chronic colonic inflammation with trinitrobenzene sulfonic acid in rats. Clin Exp Pharmacol Physiol 1992; 19: 717–22
   PubMed Web of Science ®Google Scholar
• Zea‐Iriarte W L, Makiyama K, Itsuno M, Umene Y, Hara K. Experimental‐induced colitis in rats by ethanolic solution of trinitrobenzene sulfonic acid and ethanol alone: a comparative study. Acta Med Nagasaki 1994; 39: 1–10
   Google Scholar
• Grisham M B, Volkmer C, Tso P, Yamada T. Metabolism of trinitrobenzene sulfonic acid by the rat colon produces reactive oxygen species. Gastroenterology 1991; 101: 540–7
   PubMed Web of Science ®Google Scholar
• Siems W G, Grune T, Werner A, Gerber G, Buntrock P, Schneider W. Protective influence of oxypurinol on the trinitrobenzene sulfonic acid (TNB) model of inflammatory bowel disease in rats. Cell Mol Biol 1992; 38: 189–99
   PubMed Web of Science ®Google Scholar
• Miller M JS, Thompson J H, Zhang X J, Sadowska‐Krowicka H, Kakkis J L, Munshi U K, et al. Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis. Gastroenterology 1995; 109: 1475–83
   PubMed Web of Science ®Google Scholar
• Uchida M, Tabusa F, Komatsu M, Morita S, Kanbe T, Nakagawa K. Studies on 2(1H)‐qinolinone derivatives as gastric antiulcer active agents. Synthesis and antiulcer activity of the metabolites of 2‐(4‐chlorobenzoylamino)‐3‐[2(1H)‐quinolinon‐4‐yl]propionic acid. Chem Pharm Bull 1986; 34: 4821–4
   PubMed Web of Science ®Google Scholar
• Yoshikawa T, Naito Y, Tanigawa T, Kondo M. Free radical scavenging activity of the novel anti‐ulcer agent rebamipide studied by electron spin resonance. Arzneimittelforsch 1993; 43: 363–6
   PubMed Web of Science ®Google Scholar
• Ogino K, Hobara T, Ishiyama H, Yamasaki K, Kobayashi H, Izumi Y, et al. Antiulcer mechanism of action of rebamipide, a novel antiulcer compound, on diethyldithiocarbamate‐induced antral gastric ulcers in rats. Eur J Pharmacol 1992; 212: 9–13
   PubMed Web of Science ®Google Scholar
• Yoshikawa T, Naito Y, Nakamura S, Nishimura S, Kaneko T, Linuma S, et al. Effect of rebamipide on lipid peroxidation and gastric mucosal injury induced by indomethacin in rats. Arzneimittelforsch 1993; 43: 1327–30
   PubMed Web of Science ®Google Scholar
• Kishimoto S, Fujimura J, Machine H, Shimamoto T, Kobayashi H, Shimizu S, et al. Therapeutic effects of oral rebamipide and in combination with cimetidine on experimental gastritis in rats. Res Commun Chem Pathol Pharm 1992; 78: 259–77
   PubMedGoogle Scholar
• Oka S, Ogino K, Hobara T, Yoshimura S, Okazaki Y, Takemoto T, et al. Effects of various mucosal protective drugs on diethyldithiocarbamate‐induced antral ulcer in rats. Eur J Pharmacol 1991; 197: 99–102
   PubMed Web of Science ®Google Scholar
• Traber P G, Gumicio D L, Wang W. Isolation of intestinal epithelial cells for the study of differential gene expression along the crypt‐villus axis. Am J Physiol 1991; 260: 895–903
   PubMedGoogle Scholar
• Bade O E, Andre‐Ukena S S, Beeken W L. Comparative viabilities of rat intestinal epithelial cells prepared by mechanical, enzymatic and chelating methods. Digestion 1981; 21: 25–32
   PubMed Web of Science ®Google Scholar
• Bradley P P, Priebat D A, Christensen R D, Rothstein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 1982; 78: 206–9
   PubMed Web of Science ®Google Scholar
• Krawisz J E, Sharon P, Stenson W F. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity, assessment of inflammation in rat and hamster models. Gastroenterology 1984; 87: 1344–50
   PubMed Web of Science ®Google Scholar
• Christensen H, Flyvbjerg A, Ørskov H, Laurberg S. Effect of growth hormone on the inflammatory activity of experimental colitis in rats. Scand J Gastroenterol 1993; 28: 503–11
   PubMed Web of Science ®Google Scholar
• Savin M A, Cook J D. Iron transport by isolated rat intestinal mucosal cells. Gastroenterology 1978; 75: 688–94
   PubMed Web of Science ®Google Scholar
• Redinbaugh M G, Turley R B. Adaptation of the bicinchoninic acid protein assay for use with microtiter plates and sucrose gradient fractions. Anal Biochem 1986; 153: 267–71
   PubMed Web of Science ®Google Scholar
• Beutler E. Red cell hexose monophophate shunt and other enzymes, and intermediate compounds. Red cell metabolism. A manual of biochemical methods3rd ed., E Beutler. Grune & Stratton, Philadelphia 1984; 68–135
   Google Scholar
• Beauchamp C, Fridovich I. Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal Biochem 1971; 44: 276–87
   PubMed Web of Science ®Google Scholar
• Weiss S J. Tissue destruction by neutrophils. N Engl J Med 1989; 320: 365–76
   PubMed Web of Science ®Google Scholar
• Henson P M, Johnston R B. Tissue injury in inflammation, oxidants, proteinases, and cationic proteins. J Clin Invest 1987; 79: 669–74
   PubMed Web of Science ®Google Scholar
• Little J R, Einsen H N. Preparation and characterization of antibodies specific for the 2,4,6‐trinitrophenyl group. Biochemistry 1966; 5: 3385–95
   PubMed Web of Science ®Google Scholar
• Kunin S, Gallily R. Recognition and lysis of altered‐self cells by macrophages. Modification of target cells by 2,4,6‐trinitrobenzene sulfonic acid. Immunology 1983; 48: 265–72
   PubMed Web of Science ®Google Scholar
• Harada K, Toyonaga A, Mitsuyama K, Sasaki E, Tanikawa K. Role of cytokine‐induced neutrophil chemoattractant, a member of the interleukin‐8 family, in rat experimental colitis. Digestion 1944; 55: 179–84
   Google Scholar
• Boughton‐Smith N K, Wallace J L, Whittle B JR. Relationship between arachidonic acid metabolism, myeoloperoxidase activity and leukocyte infiltration in a rat model of inflammatory bowel disease. Agents Actions 1988; 25: 115–23
   PubMedGoogle Scholar
• Gurbindo C, Russo P, Sabbah S, Lohoues M J, Seidman E. Interleukin‐2 activity of colonic lamina propria mononuclear cells in a rat model of experimental colitis. Gastroenterology 1993; 104: 964–72
   PubMed Web of Science ®Google Scholar
• Vilaseca J, Salas A, Guarner F, Rodriguez R, Malagelada J R. Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitis. Gastroenterology 1990; 98: 269–77
   PubMed Web of Science ®Google Scholar
• Rachmilewitz D, Simon P L, Schwartz L W, Griswold D E, Fondacaro J D, Wasserman M A. Inflammatory mediators of experimental colitis in rats. Gastroenterology 1989; 97: 326–37
   PubMed Web of Science ®Google Scholar
• Seiichi T, Kondo T, Yoshida K, Hirokawa J, Ohtsuka Y, Kawakami Y. Effect of insulin on impaired antioxidant activities in aortic endothelial cells from diabetic rabbits. Metabolism 1992; 41: 1053–8
   PubMed Web of Science ®Google Scholar
• Trocino R A, Akazawa S, Ishibashi M, Matsumoto K, Matsuo H, Yamamoto H, et al. Significance of glutathione depletion and oxidative stress in early embryo‐genesis in glucose‐induced rat embryo culture. Diabetes 1995; 44: 1–7
   PubMed Web of Science ®Google Scholar
• Yoshida K, Hirokawa J, Tagami S, Kawakami Y, Urata Y, Kondo T. Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux. Diabetologia 1995; 38: 201–10
   PubMed Web of Science ®Google Scholar
• Yamasaki K, Ishiyama H, Imaizumi T, Kanbe T, Yabuuchi Y. Effect of OPC‐12759, a novel antiulcer agent, on chronic and acute experimental gastric ulcer, and gastric secretion in rats. Jpn J Pharmacol 1989; 49: 441–8
   PubMedGoogle Scholar