Minor Role of Hepatitis B and C Virus Infection in the Etiology of Hepatocellular Carcinoma in a Low-Endemic Area

References

• Cook G C. Hepatocellular carcinoma: one of the world's most common malignancies [editorial]. Q J Med 1985; 233: 705–8
   Google Scholar
• Vitale G C, Heuser L S, Polk H C. Malignant tumors of the liver. Surg Clin North Am 1986; 66: 723–41
   PubMedGoogle Scholar
• The Cancer Registry. Cancer incidence in Sweden 1958–1979. National Board of Health and Welfare, Stockholm 1960-1982
   Google Scholar
• Beasley R P. Hepatitis B virus. The major etiology of hepatocellular carcinoma. Cancer 1988; 61: 1942–56
   PubMed Web of Science ®Google Scholar
• Kaczynski J, Hansson G, Norkrans G, Wallerstedt S. Lack of correlation between hepatitis B virus infection and the increasing incidence of primary liver cancer in Sweden. Acta Oncol 1991; 30: 811–3
   PubMed Web of Science ®Google Scholar
• de Franchis R, Meucci G, Vecchi M, Tatarella M, Colombo M, Del Ninno E, et al. The natural history of asymptomatic hepatitis B surface antigen carriers. Ann Intern Med 1993; 118: 191–4
   PubMed Web of Science ®Google Scholar
• Choo Q L, Kuo G, Weiner A J, Overby L R, Bradley D W, Houghton M. Isolation of a cDNA clone derived from a blood‐borne non‐A, non‐B viral hepatitis genome. Science 1989; 244: 359–62
   PubMed Web of Science ®Google Scholar
• Kiyosawa K, Sodeyama T, Tanaka E, Gibo Y, Yoshizawa K, Nakano Y, et al. Interrelationship of blood transfusion, non‐A, non‐B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology 1990; 12: 641–75
   Google Scholar
• Yuki N, Hayashi N, Kasahara A, Hagiwara H, Katayama K, Fusamoto H, et al. Hepatitis B virus markers and antibodies to hepatitis C virus in Japanese patients with hepatocellular carcinoma. Dig Dis Sci 1992; 37: 65–72
   PubMed Web of Science ®Google Scholar
• Tomimatsu M, Ishiguro N, Taniai M, Okuda M, Saito A, Obata H, et al. Hepatitis C virus antibody in patients with primary liver cancer (hepatocellular carcinoma, cholangiocar‐cinoma, and combined hepatocellular‐cholangiocarcinoma) in Japan. Cancer 1993; 72: 683–8
   PubMed Web of Science ®Google Scholar
• Simonetti R G, Cottone M, Craxi A, Pagliaro L, Rapicetta M, Chionne P, et al. Prevalence of antibodies to hepatitis C virus in hepatocellular carcinoma. Lancet 1989; 2: 1338
   PubMedGoogle Scholar
• Kaklamani E, Trichopoulos D, Tzonou Zavitsanos X, Kollmantaki Y, Hatzakis A, et al. Hepatitis B and C viruses and their interaction in the origin of hepatocellular carcinoma. JAMA 1991; 265: 1974–6
   PubMed Web of Science ®Google Scholar
• Stroffolini T, Chiaramonte M, Tiribelli C, Villa E, Simonetti R G, Rapicetta M, et al. Hepatitis C virus infection, HBsAg carrier state and hepatocellular carcinoma: relative risk and population attributable risk from a case—control study in Italy. J Hepatol 1992; 16: 360–3
   PubMedGoogle Scholar
• Coltorti M, Caporaso N, Persico M, de Sio I, Marmo R, Morisco F, et al. HCV infection and hepatocellular carcinoma in cirrhotics: what is the linkage?. Dig Dis Sci 1994; 39: 1596–7
   PubMedGoogle Scholar
• Lindberg J, Lindholm A. HBsAg‐positive Swedish blood donors: natural history and origin of infection. Scand J Infect Dis 1988; 20: 377–82
   PubMed Web of Science ®Google Scholar
• Reichard O. Treatment of chronic hepatitis C [dissertation]. Karolinska Institute, Stockholm 1994
   Google Scholar
• van der Poel C L, Cuypers H T, Reesink H W. Hepatitis C virus six years on. Lancet 1994; 344: 1475–9
   PubMed Web of Science ®Google Scholar
• Anthony P P. Tumours and tumour‐like lesions of the liver and biliary tract. Pathology of the liver2nd ed., R N.M MacSween, P P Anthony, P J Scheuer. Churchill Livingstone, Edinburgh 1987; 574–645
   Google Scholar
• Regan L S. Screening for hepatocellular carcinoma in high‐risk individuals. Arch Intern Med 1989; 149: 1741–4
   PubMedGoogle Scholar
• Beasley R P, Hwang L Y, Lin C C, Chien C S. Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22,707 men in Taiwan. Lancet 1981; 2: 1129–33
   PubMed Web of Science ®Google Scholar
• Yu M W, You S L, Chang A S, Lu S N, Liaw Y F, Chen C J. Association between hepatitis C virus antibodies and hepatocellular carcinoma in Taiwan. Cancer Res 1991; 51: 5621–5
   PubMedGoogle Scholar
• Okuda K, Fujimoto I, Hanai A, Urano Y. Changing incidence of heptocellular carcinoma in Japan. Cancer Res 1987; 47: 4967–72
   PubMed Web of Science ®Google Scholar
• Johnson P J, Williams R. Hepatitis C antibodies and hepatocellular carcinoma: new clues or a false trail?. J Natl Cancer Inst 1990; 82: 986–7
   PubMedGoogle Scholar
• Sallie R, Di Bisceglie A M. Viral hepatitis and hepatocellular carcinoma. Gastroneterol Clin North Am 1994; 23: 567–79
   PubMedGoogle Scholar
• Zavitsanos X, Hatzakis A, Kaklamani E, Tzonou R, Toupadaki N, Brocksma C, et al. Association between hepatitis C virus and hepatocellular carcinoma using assays based on structural and nonstructural hepatitis C virus peptides. Cancer Res 1992; 52: 5364–7
   PubMedGoogle Scholar
• Di Bisceglie A M, Order S E, Klein J L, Waggoner J G, Sjögren M H, Kuo G, et al. The role of chronic viral hepatitis in hepatocellular carcinoma in the United States. Am J Gastroenterol 1991; 86: 335–8
   PubMed Web of Science ®Google Scholar
• Liang T J, Jeffers L J, Reddy K R, De Medina M, Parker I T, Cheinquer H, et al. Viral pathogenesis of hepatocellular carcinoma in the United States. Hepatology 1993; 18: 1326–33
   PubMed Web of Science ®Google Scholar
• Chuang W L, Chang W Y, Lu S N, Su W P, Lin Z Y, Chen S C, et al. The role of hepatitis B and C viruses in hepatocellular carcinoma in a hepatitis B endemic area. Cancer 1992; 69: 2052–4
   PubMedGoogle Scholar
• Kew M C, Houghton M, Choo Q L, Kuo G. Hepatitis C virus antibodies in southern African blacks with hepatocellular carcinoma. Lancet 1990; 1: 873–4
   Google Scholar
• Mets T, Smitz J, Ngendahayo P, Sabbe L, Bigilimana I, Ngirabatware B. Hepatitis C virus infection in African patients with liver cirrhosis or primary hepatocellular carcinoma. Scand J Gastroenterol 1993; 28: 331–4
   PubMed Web of Science ®Google Scholar
• Okuno H, Xie Z C, Lu B Y, Qin X, Takasu M, Kano H, et al. A low prevalence of anti‐hepatitis C virus antibody in patients with hepatocellular carcinoma in Guangxi province, southern China. Cancer 1994; 73: 58–62
   PubMedGoogle Scholar
• De Bac C, Stroffolini T, Gaeta G B, Taliani G, Giusti G. Pathogenic factors in cirrhosis with and without hepatocellular carcinoma: a multicenter Italian study. Hepatology 1994; 20: 1225–30
   PubMedGoogle Scholar
• Gerber M A. Relation of hepatitis C virus to hepatocellular carcinoma. J Hepatol 1993; 17: S108–11
   PubMedGoogle Scholar
• Resnick R H, Koff R. Hepatitis C‐related hepatocellular carcinoma. Arch Intern Med 1993; 153: 1672–7
   PubMed Web of Science ®Google Scholar
• Tremolada F, Benvegnù L, Casarin C, Tagger A, Alberti A. Antibody to hepatitis C virus in hepatocellular carcinoma. Lancet 1990; 1: 300–1
   Google Scholar
• Seeff L B, Buskell‐Bales Z, Wright E C, Durako S J, Alter H J, Iber F L, et al. Long‐term mortality after transfusion‐associated non‐A, non‐B hepatitis. N Engl J Med 1992; 327: 1906–11
   PubMed Web of Science ®Google Scholar
• Verbaan H, Andersson K, Eriksson S. Intravenous drug abuse—the major route of hepatitis C virus transmission among alcohol‐dependent individuals?. Scand J Gastroenterol 1993; 28: 714–8
   PubMed Web of Science ®Google Scholar
• Tsukuma H, Hiyama T, Tanaka S, Nakao S J, Yabuuchi T, Kitamura T, et al. Risk factors for hepatocellular carcinoma among patients with chronic liver disease. N Engl J Med 1993; 328: 1797–801
   PubMed Web of Science ®Google Scholar
• Sherlock S. Viruses and hepatocellular carcinoma. Gut 1994; 35: 828–32
   PubMedGoogle Scholar
• Tamburro C H, Lee H ‐M. Primary hepatic cancer in alcoholics. Clin Gastroenterol 1981; 10: 457–77
   PubMedGoogle Scholar